JPWO2023095801A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2023095801A5 JPWO2023095801A5 JP2023528269A JP2023528269A JPWO2023095801A5 JP WO2023095801 A5 JPWO2023095801 A5 JP WO2023095801A5 JP 2023528269 A JP2023528269 A JP 2023528269A JP 2023528269 A JP2023528269 A JP 2023528269A JP WO2023095801 A5 JPWO2023095801 A5 JP WO2023095801A5
- Authority
- JP
- Japan
- Prior art keywords
- positive
- cell population
- cell
- inducible regulatory
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 18
- 210000001744 T-lymphocyte Anatomy 0.000 claims 17
- 230000001939 inductive effect Effects 0.000 claims 14
- 230000001105 regulatory effect Effects 0.000 claims 14
- 102100025012 Dipeptidyl peptidase 4 Human genes 0.000 claims 6
- 101000908391 Homo sapiens Dipeptidyl peptidase 4 Proteins 0.000 claims 6
- 101000835928 Homo sapiens Signal-regulatory protein gamma Proteins 0.000 claims 6
- 102100025795 Signal-regulatory protein gamma Human genes 0.000 claims 6
- 102100039498 Cytotoxic T-lymphocyte protein 4 Human genes 0.000 claims 3
- 101000889276 Homo sapiens Cytotoxic T-lymphocyte protein 4 Proteins 0.000 claims 3
- 102100022464 5'-nucleotidase Human genes 0.000 claims 2
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims 2
- 101001046687 Homo sapiens Integrin alpha-E Proteins 0.000 claims 2
- 102100022341 Integrin alpha-E Human genes 0.000 claims 2
- 101150027879 FOXP3 gene Proteins 0.000 claims 1
- 239000012567 medical material Substances 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024175273A JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2025167219A JP2026009980A (ja) | 2021-11-24 | 2025-10-03 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021190127 | 2021-11-24 | ||
| JP2021190127 | 2021-11-24 | ||
| PCT/JP2022/043220 WO2023095801A1 (ja) | 2021-11-24 | 2022-11-22 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024175273A Division JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023095801A1 JPWO2023095801A1 (https=) | 2023-06-01 |
| JPWO2023095801A5 true JPWO2023095801A5 (https=) | 2023-10-27 |
| JP7572755B2 JP7572755B2 (ja) | 2024-10-24 |
Family
ID=86539488
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023528269A Active JP7572755B2 (ja) | 2021-11-24 | 2022-11-22 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2024175273A Active JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2025167219A Pending JP2026009980A (ja) | 2021-11-24 | 2025-10-03 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024175273A Active JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2025167219A Pending JP2026009980A (ja) | 2021-11-24 | 2025-10-03 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250018033A1 (https=) |
| EP (1) | EP4438722A4 (https=) |
| JP (3) | JP7572755B2 (https=) |
| KR (1) | KR20240116751A (https=) |
| CN (1) | CN118591619A (https=) |
| CA (1) | CA3239019A1 (https=) |
| MX (1) | MX2024006360A (https=) |
| TW (1) | TW202330911A (https=) |
| WO (1) | WO2023095801A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250352578A1 (en) * | 2021-11-24 | 2025-11-20 | Regcell Co., Ltd. | Pharmaceutical composition for treating or preventing t cell-related disorders |
| EP4663195A1 (en) * | 2023-02-08 | 2025-12-17 | Regcell Co., Ltd. | Pharmaceutical composition for treating or preventing pemphigus |
| WO2024204553A1 (ja) * | 2023-03-29 | 2024-10-03 | レグセル株式会社 | ヒト誘導性制御性ｔ細胞およびその作製方法、およびｔ細胞関連疾患を治療または予防するための医薬組成物 |
| CN116640728B (zh) * | 2023-07-24 | 2023-10-20 | 呈诺再生医学科技(北京)有限公司 | RO8191和AS2863619在诱导产生表达成人型β珠蛋白的脱核红细胞中的应用 |
| JP2025064863A (ja) * | 2023-10-06 | 2025-04-17 | 株式会社マイオリッジ | Ｔ細胞の培養方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8598344B2 (en) | 2009-11-30 | 2013-12-03 | Senex Biotechnology | CDKI pathway inhibitors and uses thereof |
| WO2013001310A1 (en) | 2011-06-30 | 2013-01-03 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Macrocyclic compounds and their use as cdk8 inhibitors |
| US20140309224A1 (en) | 2011-09-13 | 2014-10-16 | Roninson Igor B | TREATMENT OF DISEASES OR DISORDERS CAUSED BY INDUCED NFkB TRANSCRIPTIONAL ACTIVITY |
| UA117342C2 (uk) | 2012-02-02 | 2018-07-25 | Сенекс Біотекнолоджи Інк. | Селективні інгібітори cdk8/cdk19 та їх застосування як протиметастатичних та хіміопрофілактичних засобів у способах лікування раку |
| EP2888232A1 (en) | 2012-08-23 | 2015-07-01 | F. Hoffmann-La Roche AG | Novel phenyl-pyridine/pyrazine amides for the treatment of cancer |
| ES2698960T3 (es) | 2012-10-08 | 2019-02-06 | Merck Patent Gmbh | Compuestos de 2-aminopiridina |
| GB201220157D0 (en) | 2012-11-08 | 2012-12-26 | Selvita Sa | Substitute tricyclic benzimidazoles as kinase inhibitors |
| JP2016501251A (ja) | 2012-12-10 | 2016-01-18 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | がんの治療のための新規二環フェニル−ピリジン／ピラジン |
| WO2014106606A1 (en) | 2013-01-05 | 2014-07-10 | F. Hoffmann-La Roche Ag | Nove phenyl/pyridine series substitued by hydroxyethylamino for the treatment of cancer |
| WO2014123900A1 (en) | 2013-02-05 | 2014-08-14 | Sirenas Marine Discovery | Anti-cancer and anti-hiv compounds |
| WO2014154723A1 (en) | 2013-03-29 | 2014-10-02 | F. Hoffmann-La Roche Ag | Novel pyrrole derivatives for the treatment of cancer |
| WO2014194245A2 (en) | 2013-05-31 | 2014-12-04 | Nimbus Iris, Inc. | Cdk8 inhibitors and uses thereof |
| TW201605857A (zh) | 2013-10-03 | 2016-02-16 | 赫孚孟拉羅股份公司 | Ｃｄｋ８之醫療性抑制劑及其用途 |
| SG11201605178WA (en) | 2013-12-24 | 2016-07-28 | Harvard College | Cortistatin analogues and syntheses and uses thereof |
| JP6434989B2 (ja) | 2014-03-27 | 2018-12-05 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | ピリジルピペリジン |
| JP6521387B2 (ja) | 2014-04-18 | 2019-05-29 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| EP3205645B1 (en) | 2014-04-18 | 2019-10-23 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| WO2016009076A1 (en) | 2014-07-17 | 2016-01-21 | Merck Patent Gmbh | Novel naphthryidines and isoquinolines and their use as cdk8/19 inhibitors |
| JP6987338B2 (ja) * | 2016-08-05 | 2021-12-22 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | ＭＨＣＩＩ拘束性ＣＤ４＋ＦＯＸＰ３＋制御性Ｔ細胞のｅｘ ｖｉｖｏ生成及びその治療的使用 |
| CA3051469A1 (en) * | 2017-01-27 | 2018-08-02 | Abraham J And Phyllis Katz Cord Blood Foundation | T cells derived from umbilical cord blood |
| US11578067B2 (en) | 2017-01-30 | 2023-02-14 | Kyoto University | Compound, and method for producing regulatory T cells |
| US20210238551A1 (en) * | 2018-08-22 | 2021-08-05 | Osaka University | Method for Generating Regulatory T Cells |
| EP3880213A4 (en) * | 2018-11-13 | 2022-11-23 | Abraham J and Phyllis Katz Cord Blood Foundation | T CELLS WITH IMPROVED MITOCHONDRIAL FUNCTION |
| US20220018835A1 (en) * | 2018-12-07 | 2022-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale | Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes |
| CA3140904A1 (en) * | 2019-06-24 | 2020-12-30 | Amgen Inc. | Inhibition of sirp-gamma for cancer treatment |
| AU2020380072B2 (en) * | 2019-11-08 | 2025-11-27 | Good T Cells, Inc. | Epitope of regulatory T cell surface antigen, and antibody specifically binding thereto |
| WO2021226591A1 (en) * | 2020-05-08 | 2021-11-11 | Electra Therapeutics, Inc. | Sirp alpha, sirp beta 1, and sirp gamma antibodies and uses thereof |
| US20210374678A1 (en) | 2020-05-29 | 2021-12-02 | Delta Pds Co., Ltd. | Kanban-based work processing device and work processing method |
| CN115768870A (zh) * | 2020-06-01 | 2023-03-07 | 促进军事医学的亨利·M·杰克逊基金会公司 | 诱导型调节性t细胞，其生产方法及其用途 |
| US20250352578A1 (en) * | 2021-11-24 | 2025-11-20 | Regcell Co., Ltd. | Pharmaceutical composition for treating or preventing t cell-related disorders |
| EP4532697A2 (en) * | 2022-06-03 | 2025-04-09 | Beam Therapeutics Inc. | Modified regulatory t cells and methods of using the same |
| EP4596684A1 (en) * | 2022-09-26 | 2025-08-06 | Regcell Co., Ltd. | Induced regulatory t cells containing chimeric antigen receptor (car) |
-
2022
- 2022-11-22 CN CN202280078081.XA patent/CN118591619A/zh active Pending
- 2022-11-22 JP JP2023528269A patent/JP7572755B2/ja active Active
- 2022-11-22 MX MX2024006360A patent/MX2024006360A/es unknown
- 2022-11-22 KR KR1020247020228A patent/KR20240116751A/ko active Pending
- 2022-11-22 WO PCT/JP2022/043220 patent/WO2023095801A1/ja not_active Ceased
- 2022-11-22 US US18/713,026 patent/US20250018033A1/en active Pending
- 2022-11-22 TW TW111144627A patent/TW202330911A/zh unknown
- 2022-11-22 EP EP22898584.2A patent/EP4438722A4/en active Pending
- 2022-11-22 CA CA3239019A patent/CA3239019A1/en active Pending
-
2024
- 2024-10-04 JP JP2024175273A patent/JP7759136B2/ja active Active
-
2025
- 2025-10-03 JP JP2025167219A patent/JP2026009980A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2023095801A5 (https=) | ||
| US20250250562A1 (en) | Tat-induced crispr/endonuclease-based gene editing | |
| Ferrari et al. | Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers | |
| Percequillo et al. | A new genus and species of rodent from the Brazilian Atlantic Forest (Rodentia: Cricetidae: Sigmodontinae: Oryzomyini), with comments on oryzomyine biogeography | |
| Gea-Banacloche et al. | Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors | |
| Flores-Villanueva et al. | Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity | |
| Sung et al. | Expanded cytotoxic T-cell lymphocytes target the latent HIV reservoir | |
| McCutchan et al. | Subtype G and multiple forms of A/G intersubtype recombinant human immunodeficiency virus type 1 in Nigeria | |
| Keely et al. | Gene arrays at Pneumocystis carinii telomeres | |
| Cao et al. | Cellular immunity to human immunodeficiency virus type 1 (HIV-1) clades: relevance to HIV-1 vaccine trials in Uganda | |
| Haslett et al. | Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy | |
| Young | Competence in Bacillus subtilis transformation system | |
| Alexander et al. | Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys | |
| Martos et al. | A molecular phylogeny reveals paraphyly of the large genus Eulophia (Orchidaceae): a case for the reinstatement of Orthochilus | |
| Ochoa-Lugo et al. | Genetic affiliation of pre-Hispanic and contemporary Mayas through maternal linage | |
| Patiny et al. | Phylogenetic relationships and host‐plant evolution within the basal clade of Halictidae (Hymenoptera, Apoidea) | |
| CN115348870A (zh) | 通用型嵌合抗原受体t细胞及其应用 | |
| Tehranchinia et al. | Monkeypox disease with a focus on the 2022 outbreak; a narrative review | |
| Ploquin et al. | Distinct expression profiles of TGF-β1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections | |
| Patterson et al. | Systematics of the Rhinolophus landeri complex, with evidence for 3 additional Afrotropical bat species | |
| Hu et al. | Amino acid residues in the carboxy-terminal region of cottontail rabbit papillomavirus E6 influence spontaneous regression of cutaneous papillomas | |
| Valley-Omar et al. | CAPRISA 004 tenofovir microbicide trial: no impact of tenofovir gel on the HIV transmission bottleneck | |
| Chavadar et al. | Constrictifilum karadense gen. et sp. nov., a new Nostocalean genus from Maharashtra, India | |
| Sardi et al. | Adhesion and invasion of Candida albicans from periodontal pockets of patients with chronic periodontitis and diabetes to gingival human fibroblasts | |
| Chougule et al. | Roxburgh was right: Aponogeton microphyllus and Aponogeton undulatus are distinct species: RN Chougule et al. |