JPWO2023095801A5 - - Google Patents
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- JPWO2023095801A5 JPWO2023095801A5 JP2023528269A JP2023528269A JPWO2023095801A5 JP WO2023095801 A5 JPWO2023095801 A5 JP WO2023095801A5 JP 2023528269 A JP2023528269 A JP 2023528269A JP 2023528269 A JP2023528269 A JP 2023528269A JP WO2023095801 A5 JPWO2023095801 A5 JP WO2023095801A5
- Authority
- JP
- Japan
- Prior art keywords
- positive
- cell population
- cell
- inducible regulatory
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000004027 cell Anatomy 0.000 claims 18
- 210000001744 T-lymphocyte Anatomy 0.000 claims 17
- 230000001939 inductive effect Effects 0.000 claims 14
- 230000001105 regulatory effect Effects 0.000 claims 14
- 102100025012 Dipeptidyl peptidase 4 Human genes 0.000 claims 6
- 101000908391 Homo sapiens Dipeptidyl peptidase 4 Proteins 0.000 claims 6
- 101000835928 Homo sapiens Signal-regulatory protein gamma Proteins 0.000 claims 6
- 102100025795 Signal-regulatory protein gamma Human genes 0.000 claims 6
- 102100039498 Cytotoxic T-lymphocyte protein 4 Human genes 0.000 claims 3
- 101000889276 Homo sapiens Cytotoxic T-lymphocyte protein 4 Proteins 0.000 claims 3
- 102100022464 5'-nucleotidase Human genes 0.000 claims 2
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims 2
- 101001046687 Homo sapiens Integrin alpha-E Proteins 0.000 claims 2
- 102100022341 Integrin alpha-E Human genes 0.000 claims 2
- 101150027879 FOXP3 gene Proteins 0.000 claims 1
- 239000012567 medical material Substances 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024175273A JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2025167219A JP2026009980A (ja) | 2021-11-24 | 2025-10-03 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021190127 | 2021-11-24 | ||
| JP2021190127 | 2021-11-24 | ||
| PCT/JP2022/043220 WO2023095801A1 (ja) | 2021-11-24 | 2022-11-22 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024175273A Division JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023095801A1 JPWO2023095801A1 (https=) | 2023-06-01 |
| JPWO2023095801A5 true JPWO2023095801A5 (https=) | 2023-10-27 |
| JP7572755B2 JP7572755B2 (ja) | 2024-10-24 |
Family
ID=86539488
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023528269A Active JP7572755B2 (ja) | 2021-11-24 | 2022-11-22 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2024175273A Active JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2025167219A Pending JP2026009980A (ja) | 2021-11-24 | 2025-10-03 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024175273A Active JP7759136B2 (ja) | 2021-11-24 | 2024-10-04 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
| JP2025167219A Pending JP2026009980A (ja) | 2021-11-24 | 2025-10-03 | ヒト誘導性制御性ｔ細胞およびその作製方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250018033A1 (https=) |
| EP (1) | EP4438722A4 (https=) |
| JP (3) | JP7572755B2 (https=) |
| KR (1) | KR20240116751A (https=) |
| CN (1) | CN118591619A (https=) |
| CA (1) | CA3239019A1 (https=) |
| MX (1) | MX2024006360A (https=) |
| TW (1) | TW202330911A (https=) |
| WO (1) | WO2023095801A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2024006370A (es) * | 2021-11-24 | 2024-08-19 | Regcell Co Ltd | Composicion farmaceutica para tratar o prevenir trastornos relacionados con celulas t. |
| KR20250140618A (ko) * | 2023-02-08 | 2025-09-25 | 레그셀 가부시키가이샤 | 천포창을 치료 또는 예방하기 위한 의약 조성물 |
| JPWO2024204553A1 (https=) * | 2023-03-29 | 2024-10-03 | ||
| CN116640728B (zh) * | 2023-07-24 | 2023-10-20 | 呈诺再生医学科技(北京)有限公司 | RO8191和AS2863619在诱导产生表达成人型β珠蛋白的脱核红细胞中的应用 |
| JP2025064863A (ja) * | 2023-10-06 | 2025-04-17 | 株式会社マイオリッジ | Ｔ細胞の培養方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8598344B2 (en) | 2009-11-30 | 2013-12-03 | Senex Biotechnology | CDKI pathway inhibitors and uses thereof |
| WO2013001310A1 (en) | 2011-06-30 | 2013-01-03 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Macrocyclic compounds and their use as cdk8 inhibitors |
| EA027531B1 (ru) | 2011-09-13 | 2017-08-31 | Игорь Ронинсон | ЛЕЧЕНИЕ ЗАБОЛЕВАНИЙ И НАРУШЕНИЙ, ВЫЗВАННЫХ АКТИВНОСТЬЮ ТРАНСКРИПЦИОННОГО ФАКТОРА NF-κB |
| KR20150023223A (ko) | 2012-02-02 | 2015-03-05 | 세넥스 바이오테크놀러지 인코포레이티드 | Ｃｄｋ8/ｃｄｋ19 선택성 억제제 및 암에 대한 항-전이 및 화학예방 방법에서 이들의 용도 |
| RU2015107550A (ru) | 2012-08-23 | 2016-10-10 | Ф. Хоффманн-Ля Рош Аг | Новые фенилпиридин/пиразинамиды для лечения рака |
| WO2014063778A1 (en) | 2012-10-08 | 2014-05-01 | Merck Patent Gmbh | 2-aminopyridine compounds |
| GB201220157D0 (en) | 2012-11-08 | 2012-12-26 | Selvita Sa | Substitute tricyclic benzimidazoles as kinase inhibitors |
| HK1213544A1 (zh) | 2012-12-10 | 2016-07-08 | 霍夫曼-拉罗奇有限公司 | 新型二环苯基-吡啶/吡嗪用於治疗癌症 |
| WO2014106606A1 (en) | 2013-01-05 | 2014-07-10 | F. Hoffmann-La Roche Ag | Nove phenyl/pyridine series substitued by hydroxyethylamino for the treatment of cancer |
| WO2014123900A1 (en) | 2013-02-05 | 2014-08-14 | Sirenas Marine Discovery | Anti-cancer and anti-hiv compounds |
| WO2014154723A1 (en) | 2013-03-29 | 2014-10-02 | F. Hoffmann-La Roche Ag | Novel pyrrole derivatives for the treatment of cancer |
| WO2014194245A2 (en) | 2013-05-31 | 2014-12-04 | Nimbus Iris, Inc. | Cdk8 inhibitors and uses thereof |
| TW201605857A (zh) | 2013-10-03 | 2016-02-16 | 赫孚孟拉羅股份公司 | Ｃｄｋ８之醫療性抑制劑及其用途 |
| AU2014369834B2 (en) | 2013-12-24 | 2018-12-20 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses and uses thereof |
| WO2015144290A1 (en) | 2014-03-27 | 2015-10-01 | Merck Patent Gmbh | Pyridyl piperidines |
| JP6529085B2 (ja) | 2014-04-18 | 2019-06-12 | 武田薬品工業株式会社 | 複素環化合物 |
| JP6521387B2 (ja) | 2014-04-18 | 2019-05-29 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| JP2017522324A (ja) | 2014-07-17 | 2017-08-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 新規ナフチリジン及びイソキノリンならびにｃｄｋ８／１９阻害剤としてのその使用 |
| US11365392B2 (en) * | 2016-08-05 | 2022-06-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Ex vivo generation of MHCII restricted CD4+ FOXP3+ regulatory T cells and therapeutic uses thereof |
| CA3051469A1 (en) * | 2017-01-27 | 2018-08-02 | Abraham J And Phyllis Katz Cord Blood Foundation | T cells derived from umbilical cord blood |
| CN114921468A (zh) | 2017-01-30 | 2022-08-19 | 国立大学法人京都大学 | 新型化合物以及调节性t细胞的制造方法 |
| US20210238551A1 (en) * | 2018-08-22 | 2021-08-05 | Osaka University | Method for Generating Regulatory T Cells |
| WO2020102321A1 (en) * | 2018-11-13 | 2020-05-22 | Abraham J And Phyllis Katz Cord Blood Foundation | T cells with improved mitochondrial function |
| EP3891270A1 (en) * | 2018-12-07 | 2021-10-13 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes |
| JP7763666B2 (ja) * | 2019-06-24 | 2025-11-04 | アムジェン インコーポレイテッド | 癌治療のためのＳＩＲＰγの阻害 |
| US20250243272A1 (en) * | 2019-11-08 | 2025-07-31 | Good T Cells, Inc. | Epitope of regulatory t cell surface antigen, and antibody specifically binding thereto |
| JP2023525298A (ja) * | 2020-05-08 | 2023-06-15 | エレクトラ・セラピューティクス・インコーポレイテッド | Ｓｉｒｐアルファおよびｓｉｒｐベータ１抗体、ならびにそれらの使用 |
| US20210374678A1 (en) | 2020-05-29 | 2021-12-02 | Delta Pds Co., Ltd. | Kanban-based work processing device and work processing method |
| KR20230019157A (ko) * | 2020-06-01 | 2023-02-07 | 더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드 | 유도 조절 t 세포, 이의 제조 방법, 및 용도 |
| MX2024006370A (es) * | 2021-11-24 | 2024-08-19 | Regcell Co Ltd | Composicion farmaceutica para tratar o prevenir trastornos relacionados con celulas t. |
| EP4532697A2 (en) * | 2022-06-03 | 2025-04-09 | Beam Therapeutics Inc. | Modified regulatory t cells and methods of using the same |
| EP4596684A1 (en) * | 2022-09-26 | 2025-08-06 | Regcell Co., Ltd. | Induced regulatory t cells containing chimeric antigen receptor (car) |
-
2022
- 2022-11-22 US US18/713,026 patent/US20250018033A1/en active Pending
- 2022-11-22 CN CN202280078081.XA patent/CN118591619A/zh active Pending
- 2022-11-22 WO PCT/JP2022/043220 patent/WO2023095801A1/ja not_active Ceased
- 2022-11-22 EP EP22898584.2A patent/EP4438722A4/en active Pending
- 2022-11-22 MX MX2024006360A patent/MX2024006360A/es unknown
- 2022-11-22 CA CA3239019A patent/CA3239019A1/en active Pending
- 2022-11-22 TW TW111144627A patent/TW202330911A/zh unknown
- 2022-11-22 JP JP2023528269A patent/JP7572755B2/ja active Active
- 2022-11-22 KR KR1020247020228A patent/KR20240116751A/ko active Pending
-
2024
- 2024-10-04 JP JP2024175273A patent/JP7759136B2/ja active Active
-
2025
- 2025-10-03 JP JP2025167219A patent/JP2026009980A/ja active Pending
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