JPWO2023066735A5 - - Google Patents

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Publication number
JPWO2023066735A5
JPWO2023066735A5 JP2024523408A JP2024523408A JPWO2023066735A5 JP WO2023066735 A5 JPWO2023066735 A5 JP WO2023066735A5 JP 2024523408 A JP2024523408 A JP 2024523408A JP 2024523408 A JP2024523408 A JP 2024523408A JP WO2023066735 A5 JPWO2023066735 A5 JP WO2023066735A5
Authority
JP
Japan
Prior art keywords
cells
hematopoietic
inhibitor
population
hematopoietic stem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024523408A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024544746A (ja
JP2024544746A5 (https=
Publication date
Priority claimed from GBGB2114972.9A external-priority patent/GB202114972D0/en
Application filed filed Critical
Publication of JP2024544746A publication Critical patent/JP2024544746A/ja
Publication of JP2024544746A5 publication Critical patent/JP2024544746A5/ja
Publication of JPWO2023066735A5 publication Critical patent/JPWO2023066735A5/ja
Pending legal-status Critical Current

Links

JP2024523408A 2021-10-19 2022-10-11 遺伝子治療 Pending JP2024544746A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2114972.9A GB202114972D0 (en) 2021-10-19 2021-10-19 Gene therapy
GB2114972.9 2021-10-19
PCT/EP2022/078295 WO2023066735A1 (en) 2021-10-19 2022-10-11 Gene therapy

Publications (3)

Publication Number Publication Date
JP2024544746A JP2024544746A (ja) 2024-12-04
JP2024544746A5 JP2024544746A5 (https=) 2025-10-20
JPWO2023066735A5 true JPWO2023066735A5 (https=) 2025-10-20

Family

ID=78718495

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024523408A Pending JP2024544746A (ja) 2021-10-19 2022-10-11 遺伝子治療

Country Status (6)

Country Link
US (1) US20240408145A1 (https=)
EP (1) EP4419543A1 (https=)
JP (1) JP2024544746A (https=)
CA (1) CA3235572A1 (https=)
GB (1) GB202114972D0 (https=)
WO (1) WO2023066735A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202208550D0 (en) * 2022-06-10 2022-07-27 Ospedale San Raffaele Srl Cyclosporin h and uses thereof
CN120265314A (zh) * 2022-09-28 2025-07-04 瑞泽恩制药公司 抗体抗性修饰受体以增强基于细胞的疗法
EP4602153A1 (en) 2022-10-11 2025-08-20 Fondazione Telethon ETS 3d cell culture methods
EP4534654A1 (en) * 2023-10-02 2025-04-09 Consorcio Centro de Investigación Biomédica en Red Pre-stimulation method of cd34+ cells to achieve clinically relevant gene editing frequencies
WO2025083700A1 (en) * 2023-10-20 2025-04-24 Indian Institute Of Science Education And Research, Bhopal A small molecule formulation (transducemax) for maximal gene delivery by lentiviral transduction and method of preparation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US5723315A (en) 1996-08-23 1998-03-03 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
DE69729007T2 (de) 1996-08-07 2005-04-07 Darwin Discovery Ltd., Slough Hydroxamsäure- und carbonsäure-derivate mit mmp und tnf hemmender wirkung
US6126939A (en) 1996-09-03 2000-10-03 Yeda Research And Development Co. Ltd. Anti-inflammatory dipeptide and pharmaceutical composition thereof
PL332875A1 (en) 1996-10-17 1999-10-25 Oxford Biomedica Ltd Retroviral vectors
AU2016261358B2 (en) * 2015-05-11 2021-09-16 Editas Medicine, Inc. Optimized CRISPR/Cas9 systems and methods for gene editing in stem cells
WO2017075274A1 (en) * 2015-10-27 2017-05-04 Children's Hospital Medical Center Use of mapk inhibitors to reduce loss of hematopoietic stem cells during ex vivo culture and/or genetic manipulation
MA46018A (fr) * 2016-08-19 2019-06-26 Bluebird Bio Inc Activateurs d'édition du génome
JP7175277B2 (ja) * 2017-01-27 2022-11-18 チルドレンズ ホスピタル メディカル センター 造血幹細胞の生着活性を向上させる方法
SG11202012978VA (en) 2018-06-25 2021-01-28 Ospedale San Raffaele Srl Gene therapy

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