JPWO2023038027A5 - - Google Patents
Info
- Publication number
- JPWO2023038027A5 JPWO2023038027A5 JP2023546947A JP2023546947A JPWO2023038027A5 JP WO2023038027 A5 JPWO2023038027 A5 JP WO2023038027A5 JP 2023546947 A JP2023546947 A JP 2023546947A JP 2023546947 A JP2023546947 A JP 2023546947A JP WO2023038027 A5 JPWO2023038027 A5 JP WO2023038027A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- inhibitors
- test substance
- cytotoxic activity
- hif
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021145812 | 2021-09-07 | ||
| PCT/JP2022/033445 WO2023038027A1 (ja) | 2021-09-07 | 2022-09-06 | セノリシス薬のスクリーニング方法及びセノリシス薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023038027A1 JPWO2023038027A1 (https=) | 2023-03-16 |
| JPWO2023038027A5 true JPWO2023038027A5 (https=) | 2025-09-12 |
Family
ID=85507622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023546947A Pending JPWO2023038027A1 (https=) | 2021-09-07 | 2022-09-06 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250003952A1 (https=) |
| EP (1) | EP4400117A4 (https=) |
| JP (1) | JPWO2023038027A1 (https=) |
| CN (1) | CN117915953A (https=) |
| TW (1) | TW202327606A (https=) |
| WO (1) | WO2023038027A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024135719A1 (ja) * | 2022-12-22 | 2024-06-27 | 国立大学法人京都大学 | ＰＧＡＭ－Ｃｈｋ１結合阻害剤を含む肺疾患、肝疾患又は腎疾患の治療剤 |
| CN117511855B (zh) * | 2023-11-09 | 2024-11-19 | 南京医科大学 | Epha抑制剂在诱导减数分裂中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1252852A1 (zh) * | 2015-05-29 | 2019-06-06 | Arrowhead Pharmaceuticals, Inc. | 阻止HIF2α基因表达的组合物及方法 |
| WO2017008060A1 (en) * | 2015-07-08 | 2017-01-12 | Unity Biotechnology, Inc. | Compositions and methods for treating senescence-associated diseases and disorders |
| JP6854515B2 (ja) | 2017-05-12 | 2021-04-07 | 国立大学法人京都大学 | 解糖系代謝制御物質のスクリーニング方法及び解糖系代謝制御剤 |
| GB201708456D0 (en) * | 2017-05-26 | 2017-07-12 | Medical Res Council | Senolytic compounds |
| WO2019104065A1 (en) * | 2017-11-22 | 2019-05-31 | Turrinii Pharmaceutical, Llc | Anti-aging methods and compositions |
| US20200360386A1 (en) * | 2017-12-30 | 2020-11-19 | Unity Biotechnology, Inc. | Inhibitors of HSP90, PI3-Kinase, Proteasome, HDAC, and P97 Pathways for Selective Removal of Senescent Cells in the Treatment of Age Related Conditions |
| SG11202105577TA (en) * | 2019-01-09 | 2021-06-29 | Arrowhead Pharmaceuticals Inc | Rnai agents for inhibiting expression of hif-2 alpha (epas1), compositions thereof, and methods of use |
-
2022
- 2022-09-06 US US18/689,170 patent/US20250003952A1/en active Pending
- 2022-09-06 WO PCT/JP2022/033445 patent/WO2023038027A1/ja not_active Ceased
- 2022-09-06 CN CN202280060565.1A patent/CN117915953A/zh active Pending
- 2022-09-06 JP JP2023546947A patent/JPWO2023038027A1/ja active Pending
- 2022-09-06 EP EP22867349.7A patent/EP4400117A4/en active Pending
- 2022-09-07 TW TW111133922A patent/TW202327606A/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2023038027A5 (https=) | ||
| JP7326159B2 (ja) | ドラベ症候群の処置方法 | |
| NO20071776L (no) | Kinoksaliner som B RAF inhibitorer. | |
| JP2022017263A (ja) | アンジェルマン症候群および関連する障害の処置方法 | |
| Quirion | Cholinergic markers in Alzheimer disease and the autoregulation of acetylcholine release | |
| Sun et al. | Chronic atomoxetine treatment during adolescence decreases impulsive choice, but not impulsive action, in adult rats and alters markers of synaptic plasticity in the orbitofrontal cortex | |
| KR100832026B1 (ko) | 세로토닌 재흡수 저해제와 5-ｈｔ2ｃ 길항제, 역성 효현제또는 부분 효현제의 조합 | |
| NO20071246L (no) | Kinazolinonderivater og deres anvendelse som B-RAF-inhibitorer. | |
| NO20070199L (no) | Substituerte kinazoloner som anti-kreftmidler | |
| Sałat et al. | Antinociceptive, antiallodynic and antihyperalgesic effects of the 5-HT1A receptor selective agonist, NLX-112 in mouse models of pain | |
| Sofuoglu et al. | Cholinergic functioning in stimulant addiction: implications for medications development | |
| US20150352107A1 (en) | Alpha7 neuronal nicotinic receptor ligand and antipsychotic compositions | |
| NO20073719L (no) | Kjemiske forbindelser | |
| NO20070566L (no) | Azin-karboksamider som antikreftmiddel | |
| NO20084202L (no) | 4-anilinoquinolin-3-carboksamider som CSF-1R kinase inhibitorer | |
| JP7701403B2 (ja) | 遺伝毒性ストレスにより誘導されるＩＫＫ／ＮＦ－κＢ経路の選択的阻害剤 | |
| WO2007112322A3 (en) | Indole compounds having sphingosine-1-phosphate (s1p) receptor agonist and/or antagonist biological activity | |
| US20060281788A1 (en) | Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor | |
| DK2970222T3 (en) | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | |
| NO20091766L (no) | Spiro-piperidinderivater | |
| KR20080103965A (ko) | 신경 니코틴 수용체 리간드 및 이의 용도 | |
| CN101534833B (zh) | 烟碱脱敏剂及选择、测试及使用它们的方法 | |
| WO2015168518A1 (en) | Compounds and methods of treating neurological disorders | |
| Ji et al. | A-366833: a novel nicotinonitrile-substituted 3, 6-diazabicyclo [3.2. 0]-heptane α4β2 nicotinic acetylcholine receptor selective agonist: synthesis, analgesic efficacy and tolerability profile in animal models | |
| Undem et al. | Characterization of the vanilloid receptor 1 antagonist iodo-resiniferatoxin on the afferent and efferent function of vagal sensory C-fibers |