JPWO2022145178A1 - - Google Patents

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Publication number
JPWO2022145178A1
JPWO2022145178A1 JP2022572955A JP2022572955A JPWO2022145178A1 JP WO2022145178 A1 JPWO2022145178 A1 JP WO2022145178A1 JP 2022572955 A JP2022572955 A JP 2022572955A JP 2022572955 A JP2022572955 A JP 2022572955A JP WO2022145178 A1 JPWO2022145178 A1 JP WO2022145178A1
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JP
Japan
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JP2022572955A
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Japanese (ja)
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JP7777830B2 (ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y403/00Carbon-nitrogen lyases (4.3)
    • C12Y403/01Ammonia-lyases (4.3.1)
    • C12Y403/01024Phenylalanine ammonia-lyase (4.3.1.24)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2022572955A 2020-12-28 2021-12-07 フェニルアラニンアンモニアリアーゼを用いた鎖状の不飽和カルボン酸化合物の製造方法 Active JP7777830B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020219017 2020-12-28
JP2020219017 2020-12-28
PCT/JP2021/044890 WO2022145178A1 (ja) 2020-12-28 2021-12-07 フェニルアラニンアンモニアリアーゼを用いた鎖状の不飽和カルボン酸化合物の製造方法

Publications (2)

Publication Number Publication Date
JPWO2022145178A1 true JPWO2022145178A1 (https=) 2022-07-07
JP7777830B2 JP7777830B2 (ja) 2025-12-01

Family

ID=82260391

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022572955A Active JP7777830B2 (ja) 2020-12-28 2021-12-07 フェニルアラニンアンモニアリアーゼを用いた鎖状の不飽和カルボン酸化合物の製造方法

Country Status (5)

Country Link
US (1) US20250320481A1 (https=)
EP (1) EP4269593A4 (https=)
JP (1) JP7777830B2 (https=)
CN (1) CN116710549A (https=)
WO (1) WO2022145178A1 (https=)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012018624A2 (en) * 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
US20130005012A1 (en) * 2011-06-23 2013-01-03 Phytogene, Inc. Enzymatic system for monomer synthesis
WO2013028519A1 (en) * 2011-08-19 2013-02-28 Genomatica, Inc. Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols
JP2014525741A (ja) * 2011-06-30 2014-10-02 インビスタ テクノロジーズ エス.アー.エール.エル. ナイロン−7、ナイロン−7,7、およびポリエステルを生産するための生物変換方法
US20150337336A1 (en) * 2012-06-22 2015-11-26 Phytogene, Inc. Enzymes and methods for styrene synthesis
US20160230194A1 (en) * 2013-09-18 2016-08-11 Arizona Board Of Regents On Behalf Of Arizona State University Enzymes and Microorganisms for the Production of 1,3-Butadiene and Other Dienes
WO2019022083A1 (ja) * 2017-07-24 2019-01-31 国立研究開発法人理化学研究所 デカルボキシラーゼ、及びそれを用いた不飽和炭化水素化合物の製造方法
WO2020013951A1 (en) * 2018-07-12 2020-01-16 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
US20200048674A1 (en) * 2017-04-24 2020-02-13 The Regents Of The University Of California Biosynthesis of bioorthogonal amino acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014030376A (ja) 2012-08-02 2014-02-20 Mitsubishi Chemicals Corp ブタジエンの製造方法
JP2015228804A (ja) 2014-06-03 2015-12-21 三菱化学株式会社 2,3−ブタンジオール生産能を有する微生物およびそれを用いた2,3−ブタンジオールの製造方法、1,3−ブタジエンの製造方法

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012018624A2 (en) * 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
US20130005012A1 (en) * 2011-06-23 2013-01-03 Phytogene, Inc. Enzymatic system for monomer synthesis
JP2014525741A (ja) * 2011-06-30 2014-10-02 インビスタ テクノロジーズ エス.アー.エール.エル. ナイロン−7、ナイロン−7,7、およびポリエステルを生産するための生物変換方法
WO2013028519A1 (en) * 2011-08-19 2013-02-28 Genomatica, Inc. Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols
US20150337336A1 (en) * 2012-06-22 2015-11-26 Phytogene, Inc. Enzymes and methods for styrene synthesis
US20160230194A1 (en) * 2013-09-18 2016-08-11 Arizona Board Of Regents On Behalf Of Arizona State University Enzymes and Microorganisms for the Production of 1,3-Butadiene and Other Dienes
US20200048674A1 (en) * 2017-04-24 2020-02-13 The Regents Of The University Of California Biosynthesis of bioorthogonal amino acids
WO2019022083A1 (ja) * 2017-07-24 2019-01-31 国立研究開発法人理化学研究所 デカルボキシラーゼ、及びそれを用いた不飽和炭化水素化合物の製造方法
WO2020013951A1 (en) * 2018-07-12 2020-01-16 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALINA FILIP ET AL.: "Tailored Mutants of Phenylalanine Ammonia-Lyase from Petroselinumcrispum for the Synthesis of Bulky", CHEMCATCHEM, vol. Vol.10(12), JPN6025034462, 18 July 2018 (2018-07-18), pages 2627 - 2633, ISSN: 0005669951 *
HANSON, KENNETH R, ET AL.: "Phenylalanine ammonia-lyase: enzymicconversion of 3-(1,4-cyclohexadienyl)-L-alanine totrans-3-(1,4-c", BIOCHEMISTRY, vol. Vol.18(8), JPN6025034460, 1979, pages 1431 - 1438, ISSN: 0005669950 *

Also Published As

Publication number Publication date
JP7777830B2 (ja) 2025-12-01
EP4269593A4 (en) 2025-08-13
CN116710549A (zh) 2023-09-05
US20250320481A1 (en) 2025-10-16
WO2022145178A1 (ja) 2022-07-07
EP4269593A1 (en) 2023-11-01

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