JPWO2022145178A1 - - Google Patents
Info
- Publication number
- JPWO2022145178A1 JPWO2022145178A1 JP2022572955A JP2022572955A JPWO2022145178A1 JP WO2022145178 A1 JPWO2022145178 A1 JP WO2022145178A1 JP 2022572955 A JP2022572955 A JP 2022572955A JP 2022572955 A JP2022572955 A JP 2022572955A JP WO2022145178 A1 JPWO2022145178 A1 JP WO2022145178A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y403/00—Carbon-nitrogen lyases (4.3)
- C12Y403/01—Ammonia-lyases (4.3.1)
- C12Y403/01024—Phenylalanine ammonia-lyase (4.3.1.24)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020219017 | 2020-12-28 | ||
| JP2020219017 | 2020-12-28 | ||
| PCT/JP2021/044890 WO2022145178A1 (ja) | 2020-12-28 | 2021-12-07 | フェニルアラニンアンモニアリアーゼを用いた鎖状の不飽和カルボン酸化合物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022145178A1 true JPWO2022145178A1 (https=) | 2022-07-07 |
| JP7777830B2 JP7777830B2 (ja) | 2025-12-01 |
Family
ID=82260391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022572955A Active JP7777830B2 (ja) | 2020-12-28 | 2021-12-07 | フェニルアラニンアンモニアリアーゼを用いた鎖状の不飽和カルボン酸化合物の製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250320481A1 (https=) |
| EP (1) | EP4269593A4 (https=) |
| JP (1) | JP7777830B2 (https=) |
| CN (1) | CN116710549A (https=) |
| WO (1) | WO2022145178A1 (https=) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012018624A2 (en) * | 2010-07-26 | 2012-02-09 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
| US20130005012A1 (en) * | 2011-06-23 | 2013-01-03 | Phytogene, Inc. | Enzymatic system for monomer synthesis |
| WO2013028519A1 (en) * | 2011-08-19 | 2013-02-28 | Genomatica, Inc. | Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols |
| JP2014525741A (ja) * | 2011-06-30 | 2014-10-02 | インビスタ テクノロジーズ エス.アー.エール.エル. | ナイロン−7、ナイロン−7,7、およびポリエステルを生産するための生物変換方法 |
| US20150337336A1 (en) * | 2012-06-22 | 2015-11-26 | Phytogene, Inc. | Enzymes and methods for styrene synthesis |
| US20160230194A1 (en) * | 2013-09-18 | 2016-08-11 | Arizona Board Of Regents On Behalf Of Arizona State University | Enzymes and Microorganisms for the Production of 1,3-Butadiene and Other Dienes |
| WO2019022083A1 (ja) * | 2017-07-24 | 2019-01-31 | 国立研究開発法人理化学研究所 | デカルボキシラーゼ、及びそれを用いた不飽和炭化水素化合物の製造方法 |
| WO2020013951A1 (en) * | 2018-07-12 | 2020-01-16 | Codexis, Inc. | Engineered phenylalanine ammonia lyase polypeptides |
| US20200048674A1 (en) * | 2017-04-24 | 2020-02-13 | The Regents Of The University Of California | Biosynthesis of bioorthogonal amino acids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014030376A (ja) | 2012-08-02 | 2014-02-20 | Mitsubishi Chemicals Corp | ブタジエンの製造方法 |
| JP2015228804A (ja) | 2014-06-03 | 2015-12-21 | 三菱化学株式会社 | 2,3−ブタンジオール生産能を有する微生物およびそれを用いた2,3−ブタンジオールの製造方法、1,3−ブタジエンの製造方法 |
-
2021
- 2021-12-07 WO PCT/JP2021/044890 patent/WO2022145178A1/ja not_active Ceased
- 2021-12-07 US US18/269,745 patent/US20250320481A1/en active Pending
- 2021-12-07 JP JP2022572955A patent/JP7777830B2/ja active Active
- 2021-12-07 CN CN202180087826.4A patent/CN116710549A/zh active Pending
- 2021-12-07 EP EP21915039.8A patent/EP4269593A4/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012018624A2 (en) * | 2010-07-26 | 2012-02-09 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
| US20130005012A1 (en) * | 2011-06-23 | 2013-01-03 | Phytogene, Inc. | Enzymatic system for monomer synthesis |
| JP2014525741A (ja) * | 2011-06-30 | 2014-10-02 | インビスタ テクノロジーズ エス.アー.エール.エル. | ナイロン−7、ナイロン−7,7、およびポリエステルを生産するための生物変換方法 |
| WO2013028519A1 (en) * | 2011-08-19 | 2013-02-28 | Genomatica, Inc. | Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols |
| US20150337336A1 (en) * | 2012-06-22 | 2015-11-26 | Phytogene, Inc. | Enzymes and methods for styrene synthesis |
| US20160230194A1 (en) * | 2013-09-18 | 2016-08-11 | Arizona Board Of Regents On Behalf Of Arizona State University | Enzymes and Microorganisms for the Production of 1,3-Butadiene and Other Dienes |
| US20200048674A1 (en) * | 2017-04-24 | 2020-02-13 | The Regents Of The University Of California | Biosynthesis of bioorthogonal amino acids |
| WO2019022083A1 (ja) * | 2017-07-24 | 2019-01-31 | 国立研究開発法人理化学研究所 | デカルボキシラーゼ、及びそれを用いた不飽和炭化水素化合物の製造方法 |
| WO2020013951A1 (en) * | 2018-07-12 | 2020-01-16 | Codexis, Inc. | Engineered phenylalanine ammonia lyase polypeptides |
Non-Patent Citations (2)
| Title |
|---|
| ALINA FILIP ET AL.: "Tailored Mutants of Phenylalanine Ammonia-Lyase from Petroselinumcrispum for the Synthesis of Bulky", CHEMCATCHEM, vol. Vol.10(12), JPN6025034462, 18 July 2018 (2018-07-18), pages 2627 - 2633, ISSN: 0005669951 * |
| HANSON, KENNETH R, ET AL.: "Phenylalanine ammonia-lyase: enzymicconversion of 3-(1,4-cyclohexadienyl)-L-alanine totrans-3-(1,4-c", BIOCHEMISTRY, vol. Vol.18(8), JPN6025034460, 1979, pages 1431 - 1438, ISSN: 0005669950 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7777830B2 (ja) | 2025-12-01 |
| EP4269593A4 (en) | 2025-08-13 |
| CN116710549A (zh) | 2023-09-05 |
| US20250320481A1 (en) | 2025-10-16 |
| WO2022145178A1 (ja) | 2022-07-07 |
| EP4269593A1 (en) | 2023-11-01 |
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