JPWO2022004864A1 - - Google Patents

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Publication number
JPWO2022004864A1
JPWO2022004864A1 JP2021542548A JP2021542548A JPWO2022004864A1 JP WO2022004864 A1 JPWO2022004864 A1 JP WO2022004864A1 JP 2021542548 A JP2021542548 A JP 2021542548A JP 2021542548 A JP2021542548 A JP 2021542548A JP WO2022004864 A1 JPWO2022004864 A1 JP WO2022004864A1
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021542548A
Other languages
Japanese (ja)
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JP7215776B2 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP2020/025915 external-priority patent/WO2021131110A1/ja
Application filed filed Critical
Publication of JPWO2022004864A1 publication Critical patent/JPWO2022004864A1/ja
Priority to JP2022040623A priority Critical patent/JP2022179822A/ja
Application granted granted Critical
Publication of JP7215776B2 publication Critical patent/JP7215776B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
JP2021542548A 2020-07-01 2021-07-01 ヒト長期造血幹細胞マーカー Active JP7215776B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022040623A JP2022179822A (ja) 2020-07-01 2022-03-15 ヒト長期造血幹細胞マーカー

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/JP2020/025915 WO2021131110A1 (ja) 2018-12-28 2020-07-01 細胞階層化処理により特定の生物学的特徴を有する細胞を同定する方法およびその応用方法
JPPCT/JP2020/025915 2020-07-01
JP2021089502 2021-05-27
JP2021089502 2021-05-27
PCT/JP2021/025050 WO2022004864A1 (ja) 2020-07-01 2021-07-01 ヒト長期造血幹細胞マーカー

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022040623A Division JP2022179822A (ja) 2020-07-01 2022-03-15 ヒト長期造血幹細胞マーカー

Publications (2)

Publication Number Publication Date
JPWO2022004864A1 true JPWO2022004864A1 (zh) 2022-01-06
JP7215776B2 JP7215776B2 (ja) 2023-01-31

Family

ID=79316434

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021542548A Active JP7215776B2 (ja) 2020-07-01 2021-07-01 ヒト長期造血幹細胞マーカー
JP2022040623A Pending JP2022179822A (ja) 2020-07-01 2022-03-15 ヒト長期造血幹細胞マーカー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022040623A Pending JP2022179822A (ja) 2020-07-01 2022-03-15 ヒト長期造血幹細胞マーカー

Country Status (6)

Country Link
US (1) US20230279354A1 (zh)
EP (1) EP4177337A1 (zh)
JP (2) JP7215776B2 (zh)
KR (1) KR20230034299A (zh)
CN (1) CN116075311A (zh)
WO (1) WO2022004864A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2022255489A1 (zh) * 2021-06-04 2022-12-08
WO2023222565A1 (en) * 2022-05-16 2023-11-23 Institut National de la Santé et de la Recherche Médicale Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019146584A (ja) * 2011-06-02 2019-09-05 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ エキソビボ組織培養システムのための方法および使用
WO2019208696A1 (ja) * 2018-04-25 2019-10-31 ネクスジェン株式会社 造血幹細胞における自己複製能関連遺伝子のスクリーニング方法および当該遺伝子の使用方法
JP2020500156A (ja) * 2016-10-13 2020-01-09 プレジデント アンド フェローズ オブ ハーバード カレッジ 骨髄非破壊前処理のための組成物および方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20100362A1 (es) 2008-10-30 2010-05-27 Irm Llc Derivados de purina que expanden las celulas madre hematopoyeticas

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019146584A (ja) * 2011-06-02 2019-09-05 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ エキソビボ組織培養システムのための方法および使用
JP2020500156A (ja) * 2016-10-13 2020-01-09 プレジデント アンド フェローズ オブ ハーバード カレッジ 骨髄非破壊前処理のための組成物および方法
WO2019208696A1 (ja) * 2018-04-25 2019-10-31 ネクスジェン株式会社 造血幹細胞における自己複製能関連遺伝子のスクリーニング方法および当該遺伝子の使用方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
INDUMATHI, S. ET AL.: "Exploring the stem cell and non-stem cell constituents of human breast milk", CYTOTECHNOLOGY, vol. 65, no. 3, JPN6021036667, 2013, pages 385 - 393, XP055897230, ISSN: 0004763027, DOI: 10.1007/s10616-012-9492-8 *
NOTTA F. ET AL.: "Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment", SCIENCE, vol. 333, no. 6039, JPN6021036666, 2011, pages 218 - 221, XP055069664, ISSN: 0004763026, DOI: 10.1126/science.1201219 *

Also Published As

Publication number Publication date
US20230279354A1 (en) 2023-09-07
WO2022004864A1 (ja) 2022-01-06
CN116075311A (zh) 2023-05-05
KR20230034299A (ko) 2023-03-09
EP4177337A1 (en) 2023-05-10
JP7215776B2 (ja) 2023-01-31
JP2022179822A (ja) 2022-12-05

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