JPWO2021037941A5 - - Google Patents
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- Publication number
- JPWO2021037941A5 JPWO2021037941A5 JP2022513321A JP2022513321A JPWO2021037941A5 JP WO2021037941 A5 JPWO2021037941 A5 JP WO2021037941A5 JP 2022513321 A JP2022513321 A JP 2022513321A JP 2022513321 A JP2022513321 A JP 2022513321A JP WO2021037941 A5 JPWO2021037941 A5 JP WO2021037941A5
- Authority
- JP
- Japan
- Prior art keywords
- sirna
- shows
- mrna
- hepatocytes
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19193840.6 | 2019-08-27 | ||
| EP19193840 | 2019-08-27 | ||
| EP19219497 | 2019-12-23 | ||
| EP19219497.5 | 2019-12-23 | ||
| EP20176947.8 | 2020-05-27 | ||
| EP20176947 | 2020-05-27 | ||
| PCT/EP2020/073904 WO2021037941A1 (en) | 2019-08-27 | 2020-08-26 | Nucleic acids for inhibiting expression of c3 in a cell |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022547429A JP2022547429A (ja) | 2022-11-14 |
| JPWO2021037941A5 true JPWO2021037941A5 (zh) | 2023-08-31 |
Family
ID=72148160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513321A Pending JP2022547429A (ja) | 2019-08-27 | 2020-08-26 | 細胞におけるｃ３の発現を阻害するための核酸 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20220195436A1 (zh) |
| EP (1) | EP4022060A1 (zh) |
| JP (1) | JP2022547429A (zh) |
| KR (1) | KR20220047865A (zh) |
| CN (1) | CN114981430A (zh) |
| AU (1) | AU2020339703A1 (zh) |
| BR (1) | BR112022003513A2 (zh) |
| CA (1) | CA3149534A1 (zh) |
| CO (1) | CO2022003455A2 (zh) |
| IL (1) | IL290750A (zh) |
| MX (1) | MX2022002397A (zh) |
| WO (1) | WO2021037941A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024013334A1 (en) * | 2022-07-15 | 2024-01-18 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of agt in a cell |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL9201440A (nl) | 1992-08-11 | 1994-03-01 | Univ Leiden | Triantennaire clusterglycosiden, hun bereiding en toepassing. |
| US6074642A (en) | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| US20030096775A1 (en) | 2001-10-23 | 2003-05-22 | Isis Pharmaceuticals Inc. | Antisense modulation of complement component C3 expression |
| WO2006006948A2 (en) | 2002-11-14 | 2006-01-19 | Dharmacon, Inc. | METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY |
| WO2005116204A1 (ja) * | 2004-05-11 | 2005-12-08 | Rnai Co., Ltd. | Ｒｎａ干渉を生じさせるポリヌクレオチド、および、これを用いた遺伝子発現抑制方法 |
| RU2487716C2 (ru) * | 2007-10-03 | 2013-07-20 | Кварк Фармасьютикалс, Инк. | Новые структуры малых интерферирующих рнк (sirna) |
| CN114015692A (zh) * | 2013-03-14 | 2022-02-08 | 阿尔尼拉姆医药品有限公司 | 补体组分C5 iRNA组合物及其使用方法 |
| CN105814205B (zh) | 2013-12-12 | 2019-11-19 | 阿尔尼拉姆医药品有限公司 | 补体成分iRNA组合物及其使用方法 |
| WO2015123264A1 (en) * | 2014-02-11 | 2015-08-20 | Alnylam Pharmaceuticals, Inc. | Ketohexokinase (khk) irna compositions and methods of use thereof |
| WO2016201301A1 (en) * | 2015-06-12 | 2016-12-15 | Alnylam Pharmaceuticals, Inc. | Complement component c5 irna compositions and methods of use thereof |
| EP3228326A1 (en) * | 2016-04-05 | 2017-10-11 | Silence Therapeutics GmbH | Nucleic acid linked to a trivalent glycoconjugate |
| US11866701B2 (en) * | 2017-11-01 | 2024-01-09 | Alnylam Pharmaceuticals, Inc. | Complement component C3 iRNA compositions and methods of use thereof |
| CA3119234A1 (en) | 2018-11-23 | 2020-05-28 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of c3 in a cell |
-
2020
- 2020-08-26 CA CA3149534A patent/CA3149534A1/en active Pending
- 2020-08-26 EP EP20758259.4A patent/EP4022060A1/en not_active Withdrawn
- 2020-08-26 KR KR1020227009600A patent/KR20220047865A/ko unknown
- 2020-08-26 MX MX2022002397A patent/MX2022002397A/es unknown
- 2020-08-26 WO PCT/EP2020/073904 patent/WO2021037941A1/en unknown
- 2020-08-26 CN CN202080074954.0A patent/CN114981430A/zh active Pending
- 2020-08-26 BR BR112022003513A patent/BR112022003513A2/pt unknown
- 2020-08-26 JP JP2022513321A patent/JP2022547429A/ja active Pending
- 2020-08-26 AU AU2020339703A patent/AU2020339703A1/en active Pending
- 2020-08-26 US US17/612,120 patent/US20220195436A1/en active Pending
-
2022
- 2022-02-20 IL IL290750A patent/IL290750A/en unknown
- 2022-03-24 CO CONC2022/0003455A patent/CO2022003455A2/es unknown
- 2022-05-26 US US17/825,376 patent/US11753642B2/en active Active
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