JPWO2021035179A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2021035179A5
JPWO2021035179A5 JP2022510971A JP2022510971A JPWO2021035179A5 JP WO2021035179 A5 JPWO2021035179 A5 JP WO2021035179A5 JP 2022510971 A JP2022510971 A JP 2022510971A JP 2022510971 A JP2022510971 A JP 2022510971A JP WO2021035179 A5 JPWO2021035179 A5 JP WO2021035179A5
Authority
JP
Japan
Prior art keywords
item
receptor
composition
pharmaceutical composition
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022510971A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022545226A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/047503 external-priority patent/WO2021035179A1/fr
Publication of JP2022545226A publication Critical patent/JP2022545226A/ja
Publication of JPWO2021035179A5 publication Critical patent/JPWO2021035179A5/ja
Pending legal-status Critical Current

Links

JP2022510971A 2019-08-21 2020-08-21 神経学的疾患のための組成物および方法 Pending JP2022545226A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962889963P 2019-08-21 2019-08-21
US62/889,963 2019-08-21
PCT/US2020/047503 WO2021035179A1 (fr) 2019-08-21 2020-08-21 Compositions et méthodes de traitement de maladies neurologiques

Publications (2)

Publication Number Publication Date
JP2022545226A JP2022545226A (ja) 2022-10-26
JPWO2021035179A5 true JPWO2021035179A5 (fr) 2023-08-29

Family

ID=72356519

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022510971A Pending JP2022545226A (ja) 2019-08-21 2020-08-21 神経学的疾患のための組成物および方法

Country Status (7)

Country Link
US (1) US20220348635A1 (fr)
EP (1) EP4017874A1 (fr)
JP (1) JP2022545226A (fr)
CN (1) CN114746450A (fr)
AU (1) AU2020334147A1 (fr)
CA (1) CA3151920A1 (fr)
WO (1) WO2021035179A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023092055A1 (fr) * 2021-11-19 2023-05-25 President And Fellows Of Harvard College Éléments régulateurs de gènes spécifiques de nocicepteurs pour le traitement de la douleur
WO2023147590A2 (fr) * 2022-01-31 2023-08-03 Howard Hughes Medical Institute Canaux ioniques modifiés sensibles à un ligand et méthodes d'utilisation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995013365A1 (fr) 1993-11-09 1995-05-18 Targeted Genetics Corporation Production de titres eleves de vecteurs d'aav recombinants
FR2756297B1 (fr) 1996-11-22 1999-01-08 Centre Nat Rech Scient Procede de production de virus recombinants
AU8672198A (en) 1997-07-31 1999-02-22 Chiron Corporation Method enabling readministration of aav vector via immunosuppression of host
US6566118B1 (en) 1997-09-05 2003-05-20 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
CA2830694C (fr) 1997-09-05 2018-02-27 Genzyme Corporation Procedes de generation de preparations de vecteurs de aav recombinants dont le titre est eleve et qui sont exemptes de virus assistant
US6989264B2 (en) 1997-09-05 2006-01-24 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
CA2348382C (fr) 1998-11-10 2013-09-17 The University Of North Carolina At Chapel Hill Vecteurs de papirovirus chimeriques et procedes de production et d'administration connexes
US6498244B1 (en) 1999-05-28 2002-12-24 Cell Genesys, Inc. Adeno-associated virus capsid immunologic determinants
WO2001023001A2 (fr) 1999-09-29 2001-04-05 The Trustees Of The University Of Pennsylvania Procedes de modification rapide du peg de vecteurs viraux, compositions servant a ameliorer la transduction de genes, compositions presentant une stabilite physique augmentee, et leurs utilisations
TW200412942A (en) 2002-08-06 2004-08-01 Abbott Lab Appetite control method
US9441244B2 (en) 2003-06-30 2016-09-13 The Regents Of The University Of California Mutant adeno-associated virus virions and methods of use thereof
WO2005072364A2 (fr) 2004-01-27 2005-08-11 University Of Florida Systeme d'expression baculovirus modifie utilise pour la production d'un vecteur raav pseudotype
WO2018175443A1 (fr) * 2017-03-20 2018-09-27 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thérapies géniques ciblées pour le traitement de la douleur et d'autres troubles se rapportant au système nerveux
AU2018364738A1 (en) * 2017-11-10 2020-05-28 Howard Hughes Medical Institute Modified ligand-gated ion channels and methods of use
MX2020005470A (es) * 2017-11-27 2020-11-09 Coda Biotherapeutics Inc Composiciones y metodos para enfermedades neurologicas.

Similar Documents

Publication Publication Date Title
JP7482549B2 (ja) 新規のマイクロジストロフィンおよび使用の関連する方法
JP2019089787A5 (fr)
RU2017121593A (ru) Векторы aav, нацеленные на центральную нервную систему
RU2020113681A (ru) Капсиды вариантов аденоассоциированных вирусов и методы их применения
JP2019537437A5 (fr)
JP2021503960A5 (fr)
JP2018503374A5 (fr)
RU2020108189A (ru) Композиции и способы лечения бокового амиотрофического склероза (als)
EP2933335A1 (fr) Procédé de traitement de neuropathies périphériques et sclérose latérale amyotrophique
RU2018129159A (ru) Рекомбинантные aav векторы, экспрессирующие остеопротективные гены, включая has2 и лубрицин, пригодные при лечении остеоартрита и сходных заболеваний суставов у млекопитающих
US20240018521A1 (en) Compositions and methods comprising engineered short nuclear rna (snrna)
US20230321277A1 (en) Novel polynucleotides encoding a human fkrp protein
RU2018145010A (ru) Оптимизированные гены и экспрессионные кассеты cln1, и их применение
JPWO2021035179A5 (fr)
CN114040974A (zh) 用于高效rna反式剪接的三螺旋终止子
RU2019103488A (ru) Способы и композиции для лечения нарушений и заболеваний, связанных с rdh12
Flytzanis et al. Broad gene expression throughout the mouse and marmoset brain after intravenous delivery of engineered AAV capsids
JP2019524090A5 (fr)
EP3419673B1 (fr) Thérapie génique pour le traitement d'une maladie des cellules cônes de la rétine
AU2016337034A1 (en) Antisense oligonucleotides for use in treating Alzheimer's disease
US20220370640A1 (en) Gene therapy expression system alleviating cardiac toxicity of fkrp
JPWO2022040535A5 (fr)
JPWO2020069461A5 (fr)
US20190202908A1 (en) Bi-specific agents
IL273538B1 (en) Anti-TRKB Monoclonal Antibodies and Methods of Use