JPWO2020245797A5 - - Google Patents

Claims (13)

(I) a bacterial strain belonging to the species Lactobacillus paracasei identified as Lactobacillus paracasei LPC-S01 and deposited with Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ) under accession number DSM 26760; and
(II) hyaluronic acid or a salt thereof;
A pharmaceutical composition comprising a mixture M comprising or consisting of
A pharmaceutical composition optionally comprising at least one acceptable pharmaceutical or cosmetic or food grade additive and/or excipient. 2. The pharmaceutical composition of claim 1, wherein said bacterial strain Lactobacillus paracasei LPC-S01 DSM 26760 is a viable bacterial strain. 2. The pharmaceutical composition according to claim 1, wherein said bacterial strain Lactobacillus paracasei LPC-S01 DSM 26760 is heat-inactivated or tyndallized or sonicated or gamma-irradiated, preferably heat-inactivated. A pharmaceutical composition according to any one of claims 1 to 3, wherein said pharmaceutical composition is formulated for topical skin use, preferably in a cream or pack. A pharmaceutical composition according to any one of claims 1 to 3, wherein the pharmaceutical composition is formulated for oral use, preferably in preparations for the formation of suspensions or extemporaneous suspensions. A pharmaceutical composition according to any one of claims 1 to 5 for use as a medicament. A pharmaceutical composition according to any one of claims 1 to 5 for the prophylactic and/or curative treatment of inflammation and/or infections of the skin or related diseases or conditions. 8. The pharmaceutical composition according to claim 7, wherein said skin inflammation and/or infection is induced by ultraviolet radiation. 8. The pharmaceutical composition according to claim 7, wherein said skin inflammation and/or infection is induced by Cutibacterium acnes or Propionibacterium acnes. UV radiation; and/or bad weather for the skin, preferably sun, cold or wind; and/or living conditions harmful to the skin, preferably pollution, smoking or drinking;
damage caused or induced by
A pharmaceutical composition according to any one of claims 1 to 5 for the prophylactic and/or curative treatment of and/or related diseases or conditions. said skin inflammation and/or infection or skin induced injury or related disease or condition is acute or chronic skin inflammation or infection, bacterial or viral or fungal infection of skin, abscess, Abscess, empyema, cellulitis, whitlow, furuncle, carbuncle, hidradenitis suppurativa, erysipelas, psoriasis, atopic dermatitis, acne, acute or chronic dermatitis, rosacea, couperosa , erythema, skin redness, burns, sunburn, reactivation of oral herpes, bedsores, ulcers, fissures, fistulas, pain, wounds, bruises, abrasions, ecchymosis, hematomas, abrasions, keratosis, hyperkeratosis The pharmaceutical composition according to any one of claims 7 to 10, which is selected from the group comprising or consisting of , keloids. Topical, cosmetic, dermatological use of the pharmaceutical composition according to any one of claims 1 to 4, wherein said use is
for maintaining skin homeostasis and/or as an anti-aging skin agent,
Uses. wrinkles , loss of skin elasticity or solar elastosis, dry skin, rough skin, photoaging, redness of the skin, the presence of dilated capillaries of the cheeks, nose and/or ears, age spots, skin 13. Cosmetic use according to claim 12, which is topical, cosmetic use in the treatment of abnormal or uneven pigmentation or hyperpigmentation.