JPWO2020230719A1 - - Google Patents
Info
- Publication number
- JPWO2020230719A1 JPWO2020230719A1 JP2020546516A JP2020546516A JPWO2020230719A1 JP WO2020230719 A1 JPWO2020230719 A1 JP WO2020230719A1 JP 2020546516 A JP2020546516 A JP 2020546516A JP 2020546516 A JP2020546516 A JP 2020546516A JP WO2020230719 A1 JPWO2020230719 A1 JP WO2020230719A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01035—3-Hydroxyacyl-CoA dehydrogenase (1.1.1.35)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/0104—Pyruvate kinase (2.7.1.40)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01049—Phosphoenolpyruvate carboxykinase (ATP) (4.1.1.49)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/425—Serratia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019089771 | 2019-05-10 | ||
| JP2019089771 | 2019-05-10 | ||
| PCT/JP2020/018665 WO2020230719A1 (ja) | 2019-05-10 | 2020-05-08 | ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020230719A1 true JPWO2020230719A1 (https=) | 2020-11-19 |
| JPWO2020230719A5 JPWO2020230719A5 (https=) | 2023-05-08 |
| JP7646119B2 JP7646119B2 (ja) | 2025-03-17 |
Family
ID=73290013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020546516A Active JP7646119B2 (ja) | 2019-05-10 | 2020-05-08 | ３－ヒドロキシアジピン酸、α－ヒドロムコン酸および／またはアジピン酸を生産するための遺伝子改変微生物および当該化学品の製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220228178A1 (https=) |
| EP (1) | EP3967763A4 (https=) |
| JP (1) | JP7646119B2 (https=) |
| CN (1) | CN113795589A (https=) |
| BR (1) | BR112021021601A2 (https=) |
| WO (1) | WO2020230719A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12275979B2 (en) * | 2017-11-30 | 2025-04-15 | Toray Industries, Inc. | Gene-modified microorganism for producing 3-hydroxyadipic acid, alpha-hydromuconic acid, and/or adipic acid, and production method for said chemical products |
| US20230392112A1 (en) * | 2020-11-11 | 2023-12-07 | Toray Industries, Inc. | Genetically modified microorganism for producing 3-hydroxyadipic acid and/or alpha-hydromuconic acid, and method for producing chemical product |
| US20250382643A1 (en) | 2022-02-15 | 2025-12-18 | Toray Industries, Inc. | GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID AND/OR Alpha-HYDROXYADIPIC ACID, AND METHOD FOR PRODUCING CHEMICAL PRODUCT |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009151728A2 (en) * | 2008-03-27 | 2009-12-17 | Genomatica, Inc. | Microorganisms for the production of adipic acid and other compounds |
| WO2016199856A1 (ja) * | 2015-06-10 | 2016-12-15 | 東レ株式会社 | ３－ヒドロキシアジピン酸の製造方法 |
| WO2016199858A1 (ja) * | 2015-06-10 | 2016-12-15 | 東レ株式会社 | α－ヒドロムコン酸の製造方法 |
| WO2017209103A1 (ja) * | 2016-05-31 | 2017-12-07 | 東レ株式会社 | α－ヒドロムコン酸の製造方法 |
| WO2017209102A1 (ja) * | 2016-05-31 | 2017-12-07 | 東レ株式会社 | ３－ヒドロキシアジピン酸の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100630836B1 (ko) | 2005-04-08 | 2006-10-02 | 한국과학기술원 | 인-실리코 분석을 통한 균주 개량방법 |
| DK2427544T3 (da) | 2009-05-07 | 2019-10-07 | Genomatica Inc | Mikroorganismer og fremgangsmåder til biosyntese af adipat, hexamethylendiamin og 6-aminokapronsyre |
| WO2011017560A1 (en) | 2009-08-05 | 2011-02-10 | Genomatica, Inc. | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
| BR112013001635A2 (pt) | 2010-07-26 | 2016-05-24 | Genomatica Inc | micro-organismo e métodos para a biossíntese de aromáticos, 2, 4-pentadienoato e 1,3-butadieno |
| ES2663445T3 (es) | 2012-01-30 | 2018-04-12 | Myriant Corporation | Producción de ácido mucónico a partir de microorganismos modificados genéticamente |
| TWI716752B (zh) * | 2012-12-17 | 2021-01-21 | 美商奇諾麥提卡公司 | 用於增加甲醇存在下之還原當量可利用性及用於製造與其相關己二酸、6-胺基己酸、己二胺或己內醯胺之微生物及方法 |
| EP3741865B1 (en) * | 2014-09-18 | 2024-03-13 | Genomatica, Inc. | Non-natural microbial organisms with improved energetic efficiency |
| JP7127987B2 (ja) * | 2014-12-23 | 2022-08-30 | ジェノマティカ， インコーポレイテッド | ジアミンの製造および処理方法 |
| EP3388525B1 (en) | 2015-12-11 | 2020-09-16 | Toray Industries, Inc. | Method for producing 3-oxoadipic acid by fermentation |
| KR20190026851A (ko) * | 2016-07-08 | 2019-03-13 | 에보니크 데구사 게엠베하 | 당 포스포트랜스퍼라제 시스템 (pts)을 코딩하는 유전자를 포함하는 미생물에 의한 메티오닌 또는 그의 히드록시 유사체 형태의 발효적 생산을 위한 방법 |
| US12275979B2 (en) * | 2017-11-30 | 2025-04-15 | Toray Industries, Inc. | Gene-modified microorganism for producing 3-hydroxyadipic acid, alpha-hydromuconic acid, and/or adipic acid, and production method for said chemical products |
-
2020
- 2020-05-08 EP EP20806642.3A patent/EP3967763A4/en active Pending
- 2020-05-08 JP JP2020546516A patent/JP7646119B2/ja active Active
- 2020-05-08 US US17/609,841 patent/US20220228178A1/en active Pending
- 2020-05-08 WO PCT/JP2020/018665 patent/WO2020230719A1/ja not_active Ceased
- 2020-05-08 CN CN202080033884.4A patent/CN113795589A/zh active Pending
- 2020-05-08 BR BR112021021601A patent/BR112021021601A2/pt unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009151728A2 (en) * | 2008-03-27 | 2009-12-17 | Genomatica, Inc. | Microorganisms for the production of adipic acid and other compounds |
| WO2016199856A1 (ja) * | 2015-06-10 | 2016-12-15 | 東レ株式会社 | ３－ヒドロキシアジピン酸の製造方法 |
| WO2016199858A1 (ja) * | 2015-06-10 | 2016-12-15 | 東レ株式会社 | α－ヒドロムコン酸の製造方法 |
| WO2017209103A1 (ja) * | 2016-05-31 | 2017-12-07 | 東レ株式会社 | α－ヒドロムコン酸の製造方法 |
| WO2017209102A1 (ja) * | 2016-05-31 | 2017-12-07 | 東レ株式会社 | ３－ヒドロキシアジピン酸の製造方法 |
Non-Patent Citations (6)
| Title |
|---|
| ""3-hydroxybutyryl-CoA dehydrogenase [Serratia liquwfaciens]."", [ONLINE], JPN6019004952, 11 February 2016 (2016-02-11), pages 98270 - 1, ISSN: 0005405283 * |
| ""3-hydroxybutyryl-CoA dehydrogenase [Serratia marcescens]."", [ONLINE], JPN6019004942, 28 February 2017 (2017-02-28), pages 37524 - 1, ISSN: 0005405284 * |
| ""3-hydroxybutyryl-CoA dehydrogenase [Serratia marcescens]."", [ONLINE], JPN6019004949, 18 July 2017 (2017-07-18), pages 11476 - 1, ISSN: 0005405287 * |
| ""3-hydroxybutyryl-CoA dehydrogenase [Serratia nematodiphila DZ0503SBS1]."", [ONLINE], JPN6019004944, 7 August 2014 (2014-08-07), pages 90258 - 1, ISSN: 0005405285 * |
| ""3-hydroxybutyryl-CoA dehydrogenase [Serratia plymuthica S13]."", [ONLINE], JPN6019004945, 30 January 2014 (2014-01-30), pages 43956 - 1, ISSN: 0005405286 * |
| ""3-hydroxybutyryl-CoA dehydrogenase [Serratia proteamaculans 568]."", [ONLINE], JPN6019004948, 28 January 2014 (2014-01-28), pages 40935 - 1, ISSN: 0005405288 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3967763A4 (en) | 2024-01-03 |
| US20220228178A1 (en) | 2022-07-21 |
| WO2020230719A1 (ja) | 2020-11-19 |
| EP3967763A1 (en) | 2022-03-16 |
| JP7646119B2 (ja) | 2025-03-17 |
| BR112021021601A2 (pt) | 2021-12-21 |
| CN113795589A (zh) | 2021-12-14 |
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