JPWO2020204130A1 - - Google Patents
Info
- Publication number
- JPWO2020204130A1 JPWO2020204130A1 JP2021512300A JP2021512300A JPWO2020204130A1 JP WO2020204130 A1 JPWO2020204130 A1 JP WO2020204130A1 JP 2021512300 A JP2021512300 A JP 2021512300A JP 2021512300 A JP2021512300 A JP 2021512300A JP WO2020204130 A1 JPWO2020204130 A1 JP WO2020204130A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/0705—Nucleotidyltransferases (2.7.7) mRNA guanylyltransferase (2.7.7.50)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019073163 | 2019-04-05 | ||
| JP2019073163 | 2019-04-05 | ||
| PCT/JP2020/015168 WO2020204130A1 (ja) | 2019-04-05 | 2020-04-02 | Ｒｎａのキャッピング方法、修飾ｒｎａの製造方法、及び修飾ｒｎａ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2020204130A1 true JPWO2020204130A1 (https=) | 2020-10-08 |
| JP7529284B2 JP7529284B2 (ja) | 2024-08-06 |
Family
ID=72668306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021512300A Active JP7529284B2 (ja) | 2019-04-05 | 2020-04-02 | Ｒｎａのキャッピング方法、修飾ｒｎａの製造方法、及び修飾ｒｎａ |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20220170062A1 (https=) |
| EP (1) | EP3950699A4 (https=) |
| JP (1) | JP7529284B2 (https=) |
| WO (1) | WO2020204130A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4509608A4 (en) * | 2022-03-04 | 2025-10-08 | Japan Science & Tech Agency | CAPPED RNA AND PRODUCTION METHOD THEREOF, PROTEIN PRODUCTION APPARATUS, AND PROTEIN PRODUCTION METHOD |
| WO2026014365A1 (ja) * | 2024-07-08 | 2026-01-15 | 国立大学法人東海国立大学機構 | ５´キャップアナログ |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015535430A (ja) * | 2012-11-26 | 2015-12-14 | モデルナ セラピューティクス インコーポレイテッドＭｏ | 末端修飾ｒｎａ |
| JP2017500034A (ja) * | 2013-12-13 | 2017-01-05 | モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 修飾核酸分子及びその使用 |
| US20170175129A1 (en) * | 2014-06-19 | 2017-06-22 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
| JP2017523777A (ja) * | 2014-07-17 | 2017-08-24 | モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． | ポリヌクレオチドの末端修飾 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2010659B1 (en) * | 2006-04-14 | 2014-06-18 | CellScript, Inc. | Kits and methods for generating 5' capped RNA |
| GB0706243D0 (en) * | 2007-03-30 | 2007-05-09 | Univ Southampton | Modified nucleic acids |
| US11479766B2 (en) * | 2013-12-05 | 2022-10-25 | New England Biolabs, Inc. | Methods for labeling a population of RNA molecules |
| JP2019073163A (ja) | 2017-10-17 | 2019-05-16 | 三菱自動車工業株式会社 | 四輪操舵車両 |
-
2020
- 2020-04-02 JP JP2021512300A patent/JP7529284B2/ja active Active
- 2020-04-02 WO PCT/JP2020/015168 patent/WO2020204130A1/ja not_active Ceased
- 2020-04-02 EP EP20784783.1A patent/EP3950699A4/en not_active Withdrawn
- 2020-04-02 US US17/600,844 patent/US20220170062A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015535430A (ja) * | 2012-11-26 | 2015-12-14 | モデルナ セラピューティクス インコーポレイテッドＭｏ | 末端修飾ｒｎａ |
| JP2017500034A (ja) * | 2013-12-13 | 2017-01-05 | モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 修飾核酸分子及びその使用 |
| US20170175129A1 (en) * | 2014-06-19 | 2017-06-22 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
| JP2017523777A (ja) * | 2014-07-17 | 2017-08-24 | モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． | ポリヌクレオチドの末端修飾 |
Non-Patent Citations (1)
| Title |
|---|
| WARMINSKI, M., ET AL.: "Applications of phosphate modification and labeling to study (m)RNA caps.", TOPICS IN CURRENT CHEMISTRY, vol. Vol.375:16, JPN6020022238, 2017, pages 1 - 29, ISSN: 0005238255 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7529284B2 (ja) | 2024-08-06 |
| EP3950699A4 (en) | 2023-01-18 |
| EP3950699A1 (en) | 2022-02-09 |
| US20220170062A1 (en) | 2022-06-02 |
| WO2020204130A1 (ja) | 2020-10-08 |
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