JPWO2020176894A5 - - Google Patents

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Publication number
JPWO2020176894A5
JPWO2020176894A5 JP2021550178A JP2021550178A JPWO2020176894A5 JP WO2020176894 A5 JPWO2020176894 A5 JP WO2020176894A5 JP 2021550178 A JP2021550178 A JP 2021550178A JP 2021550178 A JP2021550178 A JP 2021550178A JP WO2020176894 A5 JPWO2020176894 A5 JP WO2020176894A5
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JP
Japan
Prior art keywords
iron
aqueous
pharmaceutical composition
concentration
sucrose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021550178A
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Japanese (ja)
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JP7320611B2 (en
JP2022522009A (en
Publication date
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Priority claimed from PCT/US2020/020517 external-priority patent/WO2020176894A1/en
Publication of JP2022522009A publication Critical patent/JP2022522009A/en
Publication of JPWO2020176894A5 publication Critical patent/JPWO2020176894A5/ja
Priority to JP2023118851A priority Critical patent/JP2023139154A/en
Application granted granted Critical
Publication of JP7320611B2 publication Critical patent/JP7320611B2/en
Active legal-status Critical Current
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Claims (3)

水性鉄医薬組成物であって、
鉄スクロース；
重炭酸塩；及び
薬学的に許容され得る水性担体
を含み、
前記鉄スクロースが、患者の腎臓に保護効果を提供するための薬学的有効量で存在し、鉄は鉄（ＩＩ）及び鉄（ＩＩＩ）の両方の形態で存在し、前記医薬組成物が、約１０．５～約１１．５の範囲のｐＨ、０．０５％ｗ／ｖ～０．４１％ｗ／ｖの鉄（ＩＩ）の濃度を有し、ＧＰＣによるＭｗが３３，０００～３８，０００ダルトンである、水性鉄医薬組成物。 An aqueous iron pharmaceutical composition comprising:
iron sucrose;
bicarbonate; and a pharmaceutically acceptable aqueous carrier,
The iron sucrose is present in a pharmaceutically effective amount to provide a protective effect on the patient's kidney, the iron is present in both iron(II) and iron(III) forms, and the pharmaceutical composition comprises about pH in the range of 10.5 to about 11.5, iron(II) concentration of 0.05% w/v to 0.41% w/v, Mw by GPC of 33,000 to 38,000 An aqueous iron pharmaceutical composition which is Dalton. ２０℃で１．１３５～１．１６５の比重を有する、請求項１に記載の水性鉄組成物。 An aqueous iron composition according to claim 1, having a specific gravity of 1.135 to 1.165 at 20°C. ０．１０％ｗ／ｖ～０．２０％ｗ／ｖの鉄（ＩＩ）の濃度を有する、請求項１に記載の水性鉄組成物。 An aqueous iron composition according to claim 1, having a concentration of iron(II) between 0.10% w/v and 0.20% w/v.
JP2021550178A 2019-02-28 2020-02-28 Novel iron composition and method of making and using same Active JP7320611B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023118851A JP2023139154A (en) 2019-02-28 2023-07-21 Novel iron compositions and methods of making and using the same

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962812028P 2019-02-28 2019-02-28
US62/812,028 2019-02-28
PCT/US2020/020517 WO2020176894A1 (en) 2019-02-28 2020-02-28 Novel iron compositions and methods of making and using the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023118851A Division JP2023139154A (en) 2019-02-28 2023-07-21 Novel iron compositions and methods of making and using the same

Publications (3)

Publication Number Publication Date
JP2022522009A JP2022522009A (en) 2022-04-13
JPWO2020176894A5 true JPWO2020176894A5 (en) 2022-10-05
JP7320611B2 JP7320611B2 (en) 2023-08-03

Family

ID=70190086

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021550178A Active JP7320611B2 (en) 2019-02-28 2020-02-28 Novel iron composition and method of making and using same
JP2023118851A Pending JP2023139154A (en) 2019-02-28 2023-07-21 Novel iron compositions and methods of making and using the same

Family Applications After (1)

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JP2023118851A Pending JP2023139154A (en) 2019-02-28 2023-07-21 Novel iron compositions and methods of making and using the same

Country Status (19)

Country Link
US (4) US11292813B2 (en)
EP (2) EP3930686B1 (en)
JP (2) JP7320611B2 (en)
KR (1) KR20210133243A (en)
CN (1) CN113825496A (en)
AU (1) AU2020229381A1 (en)
CA (1) CA3131596A1 (en)
DK (1) DK3930686T3 (en)
ES (1) ES2955019T3 (en)
FI (1) FI3930686T3 (en)
HR (1) HRP20230989T1 (en)
HU (1) HUE063182T2 (en)
LT (1) LT3930686T (en)
PL (1) PL3930686T3 (en)
PT (1) PT3930686T (en)
RS (1) RS64652B1 (en)
SG (1) SG11202109323UA (en)
SI (1) SI3930686T1 (en)
WO (1) WO2020176894A1 (en)

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* Cited by examiner, † Cited by third party
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BR112023004583A2 (en) * 2020-09-11 2023-04-11 Renibus Therapeutics Inc METHOD OF TREATMENT OF CANCER WITH KIDNEY PROTECTION
WO2024069644A1 (en) * 2022-09-30 2024-04-04 West Bengal Chemical Industries Limited A pharmaceutically acceptable ferric carboxymaltose and preparation thereof

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