JPWO2020176672A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020176672A5 JPWO2020176672A5 JP2021549538A JP2021549538A JPWO2020176672A5 JP WO2020176672 A5 JPWO2020176672 A5 JP WO2020176672A5 JP 2021549538 A JP2021549538 A JP 2021549538A JP 2021549538 A JP2021549538 A JP 2021549538A JP WO2020176672 A5 JPWO2020176672 A5 JP WO2020176672A5
- Authority
- JP
- Japan
- Prior art keywords
- drawings
- invention substantially
- substantially described
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962810698P | 2019-02-26 | 2019-02-26 | |
| US62/810,698 | 2019-02-26 | ||
| US201962825228P | 2019-03-28 | 2019-03-28 | |
| US62/825,228 | 2019-03-28 | ||
| PCT/US2020/019978 WO2020176672A1 (en) | 2019-02-26 | 2020-02-26 | Combined therapies of activatable immune checkpoint inhibitors and conjugated activatable antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022523200A JP2022523200A (ja) | 2022-04-21 |
| JPWO2020176672A5 true JPWO2020176672A5 (he) | 2023-03-03 |
Family
ID=69960745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021549538A Pending JP2022523200A (ja) | 2019-02-26 | 2020-02-26 | 活性化可能な免疫チェックポイント阻害剤とコンジュゲートされた活性化可能な抗体の組み合わせ療法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220233705A1 (he) |
| EP (1) | EP3930761A1 (he) |
| JP (1) | JP2022523200A (he) |
| CN (1) | CN113677372A (he) |
| WO (1) | WO2020176672A1 (he) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017014136A (es) | 2015-05-04 | 2018-07-06 | Cytomx Therapeutics Inc | Anticuerpos anti-cd166, anticuerpos anti-cd166 activables, y metodos de uso de los mismos. |
| WO2022081541A1 (en) * | 2020-10-13 | 2022-04-21 | Chan Zuckerberg Biohub, Inc. | Compositions and methods involving antibody constructs |
| WO2023183888A1 (en) | 2022-03-23 | 2023-09-28 | Cytomx Therapeutics, Inc. | Activatable antigen-binding protein constructs and uses of the same |
| WO2023183923A1 (en) | 2022-03-25 | 2023-09-28 | Cytomx Therapeutics, Inc. | Activatable dual-anchored masked molecules and methods of use thereof |
| WO2023192973A1 (en) | 2022-04-01 | 2023-10-05 | Cytomx Therapeutics, Inc. | Activatable multispecific molecules and methods of use thereof |
| WO2023192606A2 (en) | 2022-04-01 | 2023-10-05 | Cytomx Therapeutics, Inc. | Cd3-binding proteins and methods of use thereof |
| WO2024030843A1 (en) | 2022-08-01 | 2024-02-08 | Cytomx Therapeutics, Inc. | Protease-cleavable moieties and methods of use thereof |
| WO2024030850A1 (en) | 2022-08-01 | 2024-02-08 | Cytomx Therapeutics, Inc. | Protease-cleavable substrates and methods of use thereof |
| WO2024030858A1 (en) | 2022-08-01 | 2024-02-08 | Cytomx Therapeutics, Inc. | Protease-cleavable substrates and methods of use thereof |
| TW202423953A (zh) | 2022-08-01 | 2024-06-16 | 美商Ｃｙｔｏｍｘ生物製藥公司 | 蛋白酶可切割部分及其使用方法 |
| WO2024030847A1 (en) | 2022-08-01 | 2024-02-08 | Cytomx Therapeutics, Inc. | Protease-cleavable moieties and methods of use thereof |
| WO2024216146A1 (en) | 2023-04-12 | 2024-10-17 | Cytomx Therapeutics, Inc. | Masking polypeptides, activatable cytokine constructs, and related compositions and methods |
| WO2024216170A2 (en) | 2023-04-12 | 2024-10-17 | Cytomx Therapeutics, Inc. | Activatable cytokine constructs and related compositions and methods |
| WO2024216194A1 (en) | 2023-04-12 | 2024-10-17 | Cytomx Therapeutics, Inc. | Masking polypeptides, activatable cytokine constructs, and related compositions and methods |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| EP0279862B1 (en) | 1986-08-28 | 1993-11-03 | Teijin Limited | Cytocidal antibody complex and process for its preparation |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5151510A (en) | 1990-04-20 | 1992-09-29 | Applied Biosystems, Inc. | Method of synethesizing sulfurized oligonucleotide analogs |
| DE69329503T2 (de) | 1992-11-13 | 2001-05-03 | Idec Pharma Corp | Therapeutische Verwendung von chimerischen und markierten Antikörpern, die gegen ein Differenzierung-Antigen gerichtet sind, dessen Expression auf menschliche B Lymphozyt beschränkt ist, für die Behandlung von B-Zell-Lymphoma |
| CA2620886C (en) | 2005-08-31 | 2017-03-14 | The Regents Of The University Of California | Cellular libraries of peptide sequences (clips) and methods of using the same |
| AU2008289441A1 (en) | 2007-08-22 | 2009-02-26 | Cytomx Therapeutics, Inc. | Activatable binding polypeptides and methods of identification and use thereof |
| BRPI1006141B8 (pt) | 2009-01-12 | 2021-05-25 | Cytomx Therapeutics Llc | composições de anticorpo modificado, métodos para preparar e usar as mesmas |
| WO2010129609A2 (en) | 2009-05-07 | 2010-11-11 | The Regents Of The University Of California | Antibodies and methods of use thereof |
| US9856314B2 (en) | 2012-06-22 | 2018-01-02 | Cytomx Therapeutics, Inc. | Activatable antibodies having non-binding steric moieties and methods of using the same |
| EP2882844B1 (en) | 2012-08-10 | 2018-10-03 | Cytomx Therapeutics Inc. | Protease-resistant systems for polypeptide display and methods of making and using thereof |
| CA2913732A1 (en) * | 2013-06-04 | 2014-12-11 | Cytomx Therapeutics, Inc. | Compositions and methods for conjugating activatable antibodies |
| US10336824B2 (en) * | 2015-03-13 | 2019-07-02 | Cytomx Therapeutics, Inc. | Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of thereof |
| MX2017014136A (es) * | 2015-05-04 | 2018-07-06 | Cytomx Therapeutics Inc | Anticuerpos anti-cd166, anticuerpos anti-cd166 activables, y metodos de uso de los mismos. |
| MA42447A (fr) * | 2015-07-13 | 2018-05-23 | Cytomx Therapeutics Inc | Anticorps anti-pd-1, anticorps anti-pd-1 activables, et leurs procédés d'utilisation |
| WO2018222949A1 (en) * | 2017-06-01 | 2018-12-06 | Cytomx Therapeutics, Inc. | Activatable anti-pdl1 antibodies, and methods of use thereof |
-
2020
- 2020-02-26 WO PCT/US2020/019978 patent/WO2020176672A1/en unknown
- 2020-02-26 CN CN202080027982.7A patent/CN113677372A/zh active Pending
- 2020-02-26 JP JP2021549538A patent/JP2022523200A/ja active Pending
- 2020-02-26 EP EP20714069.0A patent/EP3930761A1/en not_active Withdrawn
- 2020-02-26 US US17/433,295 patent/US20220233705A1/en active Pending