JPWO2020160537A5 - - Google Patents
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- Publication number
- JPWO2020160537A5 JPWO2020160537A5 JP2021544801A JP2021544801A JPWO2020160537A5 JP WO2020160537 A5 JPWO2020160537 A5 JP WO2020160537A5 JP 2021544801 A JP2021544801 A JP 2021544801A JP 2021544801 A JP2021544801 A JP 2021544801A JP WO2020160537 A5 JPWO2020160537 A5 JP WO2020160537A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- deuterated
- hydrogen
- undeuterated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962800239P | 2019-02-01 | 2019-02-01 | |
| US62/800,239 | 2019-02-01 | ||
| PCT/US2020/016394 WO2020160537A1 (fr) | 2019-02-01 | 2020-02-03 | Compositions de pyridine bicyclique et procédés pour leur utilisation pour la thérapie du cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022523742A JP2022523742A (ja) | 2022-04-26 |
| JPWO2020160537A5 true JPWO2020160537A5 (fr) | 2023-02-13 |
Family
ID=71842384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021544801A Pending JP2022523742A (ja) | 2019-02-01 | 2020-02-03 | 二環式ピリジン組成物およびがんの治療にそれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11572369B2 (fr) |
| EP (1) | EP3917523B1 (fr) |
| JP (1) | JP2022523742A (fr) |
| CN (1) | CN113677341B (fr) |
| AU (1) | AU2020216498A1 (fr) |
| CA (1) | CA3128377A1 (fr) |
| WO (1) | WO2020160537A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024193640A1 (fr) * | 2023-03-22 | 2024-09-26 | 上海齐鲁制药研究中心有限公司 | Inhibiteur de cdk |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271723A (en) | 1976-11-19 | 1981-06-09 | Caterpillar Tractor Co. | Power train with an auxiliary creeper drive system |
| GB9402029D0 (en) | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
| ME00355B (fr) | 2002-06-06 | 2010-06-30 | Ptp Group Ltd | Polyethylene terephtalate cristallise contenant du silicone et procede de preparation |
| US7205308B2 (en) * | 2002-09-04 | 2007-04-17 | Schering Corporation | Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors |
| MXPA06011799A (es) | 2004-04-12 | 2006-12-15 | Sankyo Co | Derivados de tienopiridina. |
| US20070021920A1 (en) | 2005-07-21 | 2007-01-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Selective resonance of chemical structures |
| WO2007103869A2 (fr) | 2006-03-06 | 2007-09-13 | Wyeth | Préparations pharmaceutiques liquides et pâteuses et procédés associés |
| JP2008260693A (ja) * | 2007-04-10 | 2008-10-30 | Daiichi Sankyo Co Ltd | チエノピリジン−２−カルボキサミド誘導体を含有する医薬組成物 |
| US8598344B2 (en) | 2009-11-30 | 2013-12-03 | Senex Biotechnology | CDKI pathway inhibitors and uses thereof |
| EP2489354A1 (fr) | 2011-02-18 | 2012-08-22 | Vironova AB | Formulation pharmaceutique de B220 pour le traitement topique de l'herpès |
| EP2797598A4 (fr) | 2011-09-13 | 2015-08-12 | Igor Roninson | Traitement de maladie ou de troubles causé(e)s par l'activité transcriptionnelle induite de nfkb |
| US9321737B2 (en) | 2012-02-02 | 2016-04-26 | Senex Biotechnology Inc | CDK8-CDK19 selective inhibitors and their use in anti-metastatic and chemopreventative methods for cancer |
| CA2890108C (fr) * | 2012-11-01 | 2021-03-02 | University Of South Carolina | Methode de traitement d'un cancer de la prostate |
| WO2014087240A2 (fr) * | 2012-12-04 | 2014-06-12 | Dalhousie University | Compositions, procédés et coffrets de prévention, de réduction et d'élimination de métastase de cancer |
| CN103012428A (zh) * | 2013-01-08 | 2013-04-03 | 中国药科大学 | 4-(五元杂环并嘧啶/吡啶取代)氨基-1H-3-吡唑甲酰胺类CDK/Aurora双重抑制剂及其用途 |
| WO2014134169A1 (fr) * | 2013-02-26 | 2014-09-04 | Senex Biotechnology, Inc. | Inhibiteurs de cdk8/19 pour utilisation dans le traitement du cancer du sein à récepteurs d'œstrogène positifs |
| US9216993B2 (en) * | 2013-03-13 | 2015-12-22 | The Regents Of The University Of Michigan | Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof |
| WO2014194245A2 (fr) | 2013-05-31 | 2014-12-04 | Nimbus Iris, Inc. | Inhibiteurs de cdk8 et leurs utilisations |
| US9937153B2 (en) | 2013-08-30 | 2018-04-10 | Merck Sharp & Dohme Ltd. | Oral pharmaceutical formulation of omarigliptin |
| EA201891279A1 (ru) | 2013-12-24 | 2019-01-31 | Президент Энд Феллоус Оф Гарвард Колледж | Аналоги кортистатина, их синтез и применения |
| US9566280B2 (en) * | 2014-01-28 | 2017-02-14 | Massachusetts Institute Of Technology | Combination therapies and methods of use thereof for treating cancer |
| BR112016017781A2 (pt) * | 2014-02-14 | 2017-08-08 | Inception 2 Inc | Compostos de pirazolona e usos dos mesmos |
| EP3154952A4 (fr) | 2014-06-10 | 2018-03-14 | University of South Carolina | Méthodes et compositions pour traiter les cancers her positifs |
| WO2016009076A1 (fr) | 2014-07-17 | 2016-01-21 | Merck Patent Gmbh | Nouvelles naphtyridines et isoquinoléines et leur utilisation à titre d'inhibiteurs de cdk8/19 |
| WO2016041618A1 (fr) * | 2014-09-15 | 2016-03-24 | Merck Patent Gmbh | Indazoles substitués et hétérocycles associés |
| CA2972771C (fr) | 2014-12-18 | 2024-06-11 | University Of South Carolina | Suppression de formation neo-intimale suite a une chirurgie vasculaire, a l'aide d'inhibiteurs de cdk8 |
| EP3370720A1 (fr) * | 2015-11-03 | 2018-09-12 | Lu License AB | Composés destinés au traitement de désordres hyperprolifératifs |
| US11014906B2 (en) | 2018-08-21 | 2021-05-25 | University Of South Carolina | Quinoline-based compounds and methods of inhibiting CDK8/19 |
| US20220226343A1 (en) * | 2019-05-21 | 2022-07-21 | University Of South Carolina | 3-amino-4-[4-[4 (dimethylcarbamoyl) phenyl]-1,4-diazepan-1-yl]thieno[2,3-b]pyridine-2-carboxamide for use in cancer therapy and formulations comprising the same |
-
2020
- 2020-02-03 CN CN202080026293.4A patent/CN113677341B/zh active Active
- 2020-02-03 CA CA3128377A patent/CA3128377A1/fr active Pending
- 2020-02-03 AU AU2020216498A patent/AU2020216498A1/en active Pending
- 2020-02-03 JP JP2021544801A patent/JP2022523742A/ja active Pending
- 2020-02-03 US US17/427,487 patent/US11572369B2/en active Active
- 2020-02-03 WO PCT/US2020/016394 patent/WO2020160537A1/fr unknown
- 2020-02-03 EP EP20749196.0A patent/EP3917523B1/fr active Active
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