JPWO2020138491A1 - - Google Patents

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Publication number
JPWO2020138491A1
JPWO2020138491A1 JP2020562548A JP2020562548A JPWO2020138491A1 JP WO2020138491 A1 JPWO2020138491 A1 JP WO2020138491A1 JP 2020562548 A JP2020562548 A JP 2020562548A JP 2020562548 A JP2020562548 A JP 2020562548A JP WO2020138491 A1 JPWO2020138491 A1 JP WO2020138491A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2020562548A
Other languages
Japanese (ja)
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JP7483630B2 (ja
JPWO2020138491A5 (https=
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Publication of JPWO2020138491A1 publication Critical patent/JPWO2020138491A1/ja
Publication of JPWO2020138491A5 publication Critical patent/JPWO2020138491A5/ja
Application granted granted Critical
Publication of JP7483630B2 publication Critical patent/JP7483630B2/ja
Active legal-status Critical Current
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Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4453Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020562548A 2018-12-27 2019-12-27 神経発達障害の予防または治療剤としてのr-ケタミンおよびその誘導体 Active JP7483630B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018245688 2018-12-27
JP2018245688 2018-12-27
PCT/JP2019/051605 WO2020138491A1 (ja) 2018-12-27 2019-12-27 神経発達障害の予防または治療剤としてのr-ケタミンおよびその誘導体

Publications (3)

Publication Number Publication Date
JPWO2020138491A1 true JPWO2020138491A1 (https=) 2020-07-02
JPWO2020138491A5 JPWO2020138491A5 (https=) 2023-01-11
JP7483630B2 JP7483630B2 (ja) 2024-05-15

Family

ID=71127068

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020562548A Active JP7483630B2 (ja) 2018-12-27 2019-12-27 神経発達障害の予防または治療剤としてのr-ケタミンおよびその誘導体

Country Status (4)

Country Link
US (1) US20220110889A1 (https=)
EP (1) EP3903775A4 (https=)
JP (1) JP7483630B2 (https=)
WO (1) WO2020138491A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3043785T1 (sl) 2013-09-13 2022-02-28 National University Corporation Chiba University Uporaba R-ketamina in njegove soli kot farmacevtska sredstva
JP7548669B2 (ja) 2018-02-15 2024-09-10 国立大学法人千葉大学 炎症性疾患若しくは骨疾患の予防又は治療剤及び医薬組成物
AU2019262197B2 (en) 2018-05-04 2024-12-19 Perception Neuroscience, Inc. Methods of treating substance abuse
CN118647595A (zh) 2021-10-12 2024-09-13 感知神经科学公司 R-氯胺酮盐及其使用方法
CA3245931A1 (en) 2022-03-14 2023-09-21 Perception Neuroscience, Inc. R-KETAMINE PHARMACEUTICAL FORMULATIONS
JP2023152104A (ja) * 2022-04-01 2023-10-16 株式会社エル・エスコーポレーション 認知機能の評価方法、及び、認知機能の評価装置

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150196501A1 (en) * 2014-01-14 2015-07-16 Children's Hospital Medical Center Compositions and methods for treating an autism spectrum disorder

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19619665C2 (de) 1996-05-15 2001-03-08 Goedecke Ag Racemattrennung von Ketamin
US20120225949A1 (en) * 2009-08-14 2012-09-06 Demitri Papalos Compositions and methods for treating bipolar disorder
US9737531B2 (en) * 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
SI3043785T1 (sl) * 2013-09-13 2022-02-28 National University Corporation Chiba University Uporaba R-ketamina in njegove soli kot farmacevtska sredstva
EP3085366A1 (en) * 2015-04-22 2016-10-26 Institut du Cerveau et de la Moelle Epiniere-ICM Nmda antagonists for the treatment of mental disorders with occurrence of aggressive and/or impulsive behavior
WO2017180589A1 (en) * 2016-04-11 2017-10-19 Auspex Pharmaceuticals, Inc. Deuterated ketamine derivatives
JP2020506231A (ja) * 2017-01-31 2020-02-27 パオロ エル マンフレディ 神経系の障害並びにその症状及び徴候の処置又は予防のため並びに疾患及び細胞の老化並びにその症状及び徴候に対する細胞保護のための化合物
WO2019065900A1 (ja) * 2017-09-27 2019-04-04 国立大学法人千葉大学 神経変性疾患あるいは認知機能障害の予防または治療剤としてのr-ケタミンおよびその誘導体

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150196501A1 (en) * 2014-01-14 2015-07-16 Children's Hospital Medical Center Compositions and methods for treating an autism spectrum disorder

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JHONSON K. M. ET AL.: "Phencyclidine: it ain’t excitin’, but it sure is toxic", 13TH INTERNATIONAL CONGRESS ON AMINO ACIDS, PEPTIDES AND PROTEINS, vol. 45, JPN6020007935, 14 August 2013 (2013-08-14), pages 588 - 589, ISSN: 0005140698 *
MOHAMMADI A. ET AL.: "Dysfunction in Brain-Derived Neurotrophic Factor Signaling Pathway and susceptibility to Schizophren", CURR. GENE THER., vol. 18, JPN6020007937, May 2018 (2018-05-01), pages 45 - 63, ISSN: 0005140696 *
YANG C. ET AL.: "R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects", TRANSL. PSYCHIATRY, vol. 5, JPN6020007934, 1 September 2015 (2015-09-01), pages 632 - 1, ISSN: 0005140697 *

Also Published As

Publication number Publication date
JP7483630B2 (ja) 2024-05-15
US20220110889A1 (en) 2022-04-14
EP3903775A4 (en) 2022-10-12
WO2020138491A1 (ja) 2020-07-02
EP3903775A1 (en) 2021-11-03

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