JPWO2020127191A5 - - Google Patents

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Publication number
JPWO2020127191A5
JPWO2020127191A5 JP2021535606A JP2021535606A JPWO2020127191A5 JP WO2020127191 A5 JPWO2020127191 A5 JP WO2020127191A5 JP 2021535606 A JP2021535606 A JP 2021535606A JP 2021535606 A JP2021535606 A JP 2021535606A JP WO2020127191 A5 JPWO2020127191 A5 JP WO2020127191A5
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JP
Japan
Prior art keywords
drug delivery
light
delivery device
stopper
reservoir
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Pending
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JP2021535606A
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Japanese (ja)
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JP2022514091A (en
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Priority claimed from PCT/EP2019/085540 external-priority patent/WO2020127191A1/en
Publication of JP2022514091A publication Critical patent/JP2022514091A/en
Publication of JPWO2020127191A5 publication Critical patent/JPWO2020127191A5/ja
Pending legal-status Critical Current

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Claims (15)

薬物送達デバイス（１０２）であって：
近位端（１１６、１１７）および遠位端（１１１）を画成する壁を含むリザーバ（１０６）と；
光反射要素（１０９ｂ、１４６）を含むストッパ（１０９）であって、リザーバ（１０６）内で遠位端（１１１）から近位端（１１６、１１７）の方向に動くことにより、リザーバ（１０６）内に収納された薬剤の一部分を排出し、それによりストッパ（１０９）位置によってリザーバ（１０６）内の薬剤の量が示されるように構成されたストッパ（１０９）と；
近位端（１１６、１１７）からストッパ（１０９）に向けて光信号を提供するように構成された発光システム（１３４）と；
ストッパ（１０９）の光反射要素における光信号の少なくとも一部分の反射によって提供された反射光信号を検出するように構成された光検出システム（１３６）であって、該反射光信号は、近位端（１１６、１１７）に向かって、リザーバ（１０６）の壁の第１の部分、および、該反射光信号を検出したことに応答して電気信号を提供するように構成された光検出器（１３６ａ）に向けて反射光信号を方向付けるように構成された形状を含む、集光器（１３６ｂ）を通って移動する、光検出システムと
を含む、前記薬物送達デバイス。 A drug delivery device (102) comprising:
a reservoir (106) comprising walls defining proximal ends (116, 117) and a distal end (111);
A stopper (109) comprising light reflective elements (109b, 146) that moves within the reservoir (106) in the direction from the distal end (111) to the proximal end (116, 117) to a stopper (109) configured to expel a portion of the medicament contained therein such that the position of the stopper (109) indicates the amount of medicament in the reservoir (106);
a lighting system (134) configured to provide a light signal from the proximal ends (116, 117) towards the stopper (109);
A light detection system (136) configured to detect a reflected light signal provided by reflection of at least a portion of the light signal at a light reflective element of the stopper (109), the reflected light signal towards (116, 117) a first portion of the wall of the reservoir (106) and a photodetector (136a) configured to provide an electrical signal in response to detecting said reflected light signal; a light detection system moving through the light collector (136b), the light detection system including a shape configured to direct the reflected light signal toward the drug delivery device. 光信号は、リザーバ（１０６）の壁の第２の部分を通って移動するように構成される、請求項１に記載の薬物送達デバイス（１０２）。 2. The drug delivery device (102) of Claim 1, wherein the optical signal is configured to travel through the second portion of the wall of the reservoir (106). 壁の第１の部分および壁の第２の部分のうちの少なくとも１つは、ストッパ（１０９）の内側面に対向している、請求項２に記載の薬物送達デバイス（１０２）。 3. The drug delivery device (102) of claim 2, wherein at least one of the first portion of the wall and the second portion of the wall faces the inner surface of the stopper (109). 近位端（１１６、１１７）の壁の第１の部分および壁の第２の部分のうちの少なくとも１つは、実質的に光学的に透明である、請求項２または３に記載の薬物送達デバイス（１０２）。 4. Drug delivery according to claim 2 or 3, wherein at least one of the first portion of the wall and the second portion of the wall of the proximal end (116, 117) is substantially optically transparent. Device (102). 発光システム（１３４）は、ストッパ（１０９）の中心部分に向けて光信号を放出する
ように構成される、請求項１～４のいずれか１項に記載の薬物送達デバイス（１０２）。 A drug delivery device (102) according to any preceding claim, wherein the light emitting system (134) is configured to emit a light signal towards a central portion of the stopper (109). 壁の第１の部分および壁の第２の部分のうちの少なくとも１つは、平坦な水平形状および平坦な傾斜形状のうちの少なくとも１つを画成する、請求項２～５のいずれか１項に記載の薬物送達デバイス（１０２）。 6. Any one of claims 2-5, wherein at least one of the first portion of the wall and the second portion of the wall defines at least one of a flat horizontal shape and a flat slanted shape. A drug delivery device (102) according to any preceding paragraph. 壁の第１の部分および壁の第２の部分のうちの少なくとも１つは、凸形状および凹形状のうちの少なくとも１つを画成する、請求項２～５のいずれか１項に記載の薬物送達デバイス（１０２）。 At least one of the first portion of the wall and the second portion of the wall defines at least one of a convex shape and a concave shape. A drug delivery device (102). 発光システム（１３４）は発光ダイオードを含み、光検出システム（１３６）は、反射光信号の輝度に基づいて電気信号を放出するように構成された光依存性のレジスタを含む、請求項１～６のいずれか１項に記載の薬物送達デバイス（１０２）。 7. The light-emitting system (134) comprises a light-emitting diode and the light-detecting system (136) comprises a light-dependent resistor configured to emit an electrical signal based on the intensity of the reflected light signal. A drug delivery device (102) according to any one of Claims 1 to 3. 発光システム（１３４）はレーザダイオードを含み、光検出システム（１３６）は、反射光信号の角度または位相に基づいて電気信号を放出するように構成されたレーザ受信機センサを含む、請求項１～７のいずれか１項に記載の薬物送達デバイス（１０２）。 The light emitting system (134) comprises a laser diode and the light detection system (136) comprises a laser receiver sensor configured to emit an electrical signal based on the angle or phase of the reflected light signal. 8. The drug delivery device (102) of any one of Clauses 7 to 8. 光検出システム（１３６）は、凹レンズを含み、光反射要素（１４６）は、円柱レンズおよび非球面レンズのうちの１つを含む、請求項１～８のいずれか１項に記載の薬物送達デバイス（１０２）。 The drug delivery device of any one of claims 1-8, wherein the light detection system (136) comprises a concave lens and the light reflecting element (146) comprises one of a cylindrical lens and an aspheric lens. (102). 光反射要素（１４６）は、ストッパ（１０９）の中心部分内に位置している、請求項１～９のいずれか１項に記載の薬物送達デバイス（１０２）。 The drug delivery device (102) according to any one of the preceding claims, wherein the light reflecting element (146) is located within the central portion of the stopper (109). 電気信号を処理して、リザーバ（１０６）内の薬剤の量を判定し、リザーバ（１０６）内の薬剤の特性を判定するように構成されたプロセッサ（１３８）を含む、請求項１～１１のいずれか１項に記載の薬物送達デバイス（１０２）。 The method of claims 1-11, comprising a processor (138) configured to process the electrical signal to determine the amount of medicament in the reservoir (106) and to determine characteristics of the medicament in the reservoir (106). A drug delivery device (102) according to any one of the preceding clauses. 薬剤リザーバ（１０６）は、好ましくは環状オレフィンコポリマー（ＣＯＣ）およびシクロオレフィンポリマー（ＣＯＰ）のうちの１つを含む光学的に透明なプラスチック材料から作られる、請求項１～１２のいずれか１項に記載の薬物送達デバイス（１０２）。 13. The drug reservoir (106) according to any one of claims 1 to 12, wherein the drug reservoir (106) is preferably made from an optically transparent plastic material comprising one of cyclic olefin copolymers (COC) and cycloolefin polymers (COP). A drug delivery device (102) according to . 発光システム（１３４）および光検出システム（１３６）は、それぞれ、ストッパ（１０９）の移動方向に対して垂直に光を放出し受けるように配置することができる、請求項１～１２のいずれか１項に記載の薬物送達デバイス（１０２）。 13. Any one of claims 1 to 12, wherein the light emitting system (134) and the light detecting system (136) are each arranged to emit and receive light perpendicular to the direction of movement of the stopper (109). A drug delivery device (102) according to any preceding paragraph. 薬物送達システム（１００）であって：
請求項１～１４のいずれか１項に記載の薬物送達デバイス（１０２）と；
外部デバイス（１０４）とを含み、該外部デバイスは：
注射デバイスのデータを受信するように構成された受信機（１５８）、および
注射デバイスのデータを処理し、結果データを生成するように構成された１つまたはそれ以上のプロセッサ（１６０）
を含む、前記薬物送達システム。 A drug delivery system (100) comprising:
a drug delivery device (102) according to any one of claims 1 to 14;
an external device (104), the external device:
a receiver (158) configured to receive injection device data; and one or more processors (160) configured to process the injection device data and generate result data.
The drug delivery system, comprising:
JP2021535606A 2018-12-19 2019-12-17 Optical configuration of the drug reservoir of the drug delivery device Pending JP2022514091A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18306737 2018-12-19
EP18306737.0 2018-12-19
PCT/EP2019/085540 WO2020127191A1 (en) 2018-12-19 2019-12-17 Optical configuration of a medicament reservoir of a drug delivery device

Publications (2)

Publication Number Publication Date
JP2022514091A JP2022514091A (en) 2022-02-09
JPWO2020127191A5 true JPWO2020127191A5 (en) 2022-11-01

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ID=65278154

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Application Number Title Priority Date Filing Date
JP2021535606A Pending JP2022514091A (en) 2018-12-19 2019-12-17 Optical configuration of the drug reservoir of the drug delivery device

Country Status (5)

Country Link
US (1) US20220031956A1 (en)
EP (1) EP3897785A1 (en)
JP (1) JP2022514091A (en)
CN (1) CN113226409A (en)
WO (1) WO2020127191A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220020108A (en) * 2020-08-11 2022-02-18 삼성전자주식회사 Drug delivery device and method for operating the same
WO2022226157A1 (en) * 2021-04-21 2022-10-27 Northwestern University Hybrid bioelectronic/engineered cell wearable system for therapeutic agents delivery and applications thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19652708C2 (en) * 1996-12-18 1999-08-12 Schott Glas Process for producing a filled plastic syringe body for medical purposes
AU2004254632B2 (en) * 2003-07-02 2009-02-12 Terumo Bct, Inc. Monitoring and control system for blood processing
TWI633902B (en) * 2010-03-22 2018-09-01 賽諾菲阿凡提斯德意志有限公司 Device, method, system and computer program for determining information related to a medical device
EP2716313A1 (en) * 2012-10-04 2014-04-09 Sanofi-Aventis Deutschland GmbH Medicament delivery device and cartridge
US9907902B2 (en) * 2013-12-20 2018-03-06 Maxim Integrated Products, Inc. Precise accurate measurement of the administration of drugs using the injection method by means of ultrasonic pulse-echo principles
WO2016036574A1 (en) * 2014-09-02 2016-03-10 Eli Lilly And Company Sensing system for detecting a piston in a medical fluid container
CN110785196B (en) * 2017-05-05 2024-05-14 赛诺菲 Cartridge for dose sensing
JP7204688B2 (en) * 2017-06-09 2023-01-16 サノフイ Electronics for dose sensing
US20190054250A1 (en) * 2017-08-17 2019-02-21 Qualcomm Incorporated Drug delivery measurement in a medicine delivery device
US20200230325A1 (en) * 2017-09-30 2020-07-23 Novo Nordisk A/S Cartridge system for a drug delivery device

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