JPWO2020120449A5 - - Google Patents

Info

Publication number

JPWO2020120449A5

JPWO2020120449A5 JP2021533341A JP2021533341A JPWO2020120449A5 JP WO2020120449 A5 JPWO2020120449 A5 JP WO2020120449A5 JP 2021533341 A JP2021533341 A JP 2021533341A JP 2021533341 A JP2021533341 A JP 2021533341A JP WO2020120449 A5 JPWO2020120449 A5 JP WO2020120449A5

Authority

JP

Japan

Prior art keywords

disorder

disorders

disease

pharmaceutical composition

following group

Prior art date

2022-12-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 150000001875 compounds Chemical class 0.000 claims 6
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
• 208000035475 disorder Diseases 0.000 claims 5
• 125000001153 fluoro group Chemical group F* 0.000 claims 5
• 229910052739 hydrogen Inorganic materials 0.000 claims 4
• 239000001257 hydrogen Substances 0.000 claims 4
• 239000008194 pharmaceutical composition Substances 0.000 claims 4
• 208000000044 Amnesia Diseases 0.000 claims 3
• 208000024714 major depressive disease Diseases 0.000 claims 3
• 208000024827 Alzheimer disease Diseases 0.000 claims 2
• 208000031091 Amnestic disease Diseases 0.000 claims 2
• 208000019901 Anxiety disease Diseases 0.000 claims 2
• 208000023105 Huntington disease Diseases 0.000 claims 2
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
• 206010041250 Social phobia Diseases 0.000 claims 2
• 102000003621 TRPC5 Human genes 0.000 claims 2
• 101150042815 TRPC5 gene Proteins 0.000 claims 2
• 230000006986 amnesia Effects 0.000 claims 2
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
• 150000002431 hydrogen Chemical class 0.000 claims 2
• 208000014674 injury Diseases 0.000 claims 2
• 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
• 230000001404 mediated effect Effects 0.000 claims 2
• 230000000626 neurodegenerative effect Effects 0.000 claims 2
• 230000001272 neurogenic effect Effects 0.000 claims 2
• 208000019906 panic disease Diseases 0.000 claims 2
• 208000028173 post-traumatic stress disease Diseases 0.000 claims 2
• 150000003839 salts Chemical class 0.000 claims 2
• 208000008811 Agoraphobia Diseases 0.000 claims 1
• 208000025978 Athletic injury Diseases 0.000 claims 1
• 208000020925 Bipolar disease Diseases 0.000 claims 1
• 208000003174 Brain Neoplasms Diseases 0.000 claims 1
• 208000014644 Brain disease Diseases 0.000 claims 1
• 206010008874 Chronic Fatigue Syndrome Diseases 0.000 claims 1
• 208000020406 Creutzfeldt Jacob disease Diseases 0.000 claims 1
• 208000003407 Creutzfeldt-Jakob Syndrome Diseases 0.000 claims 1
• 208000010859 Creutzfeldt-Jakob disease Diseases 0.000 claims 1
• 206010012335 Dependence Diseases 0.000 claims 1
• 206010012374 Depressed mood Diseases 0.000 claims 1
• 208000020401 Depressive disease Diseases 0.000 claims 1
• 208000026331 Disruptive, Impulse Control, and Conduct disease Diseases 0.000 claims 1
• 208000025967 Dissociative Identity disease Diseases 0.000 claims 1
• 208000011688 Generalised anxiety disease Diseases 0.000 claims 1
• 208000030990 Impulse-control disease Diseases 0.000 claims 1
• 208000006264 Korsakoff syndrome Diseases 0.000 claims 1
• 208000026139 Memory disease Diseases 0.000 claims 1
• 208000002193 Pain Diseases 0.000 claims 1
• 208000018737 Parkinson disease Diseases 0.000 claims 1
• 201000009916 Postpartum depression Diseases 0.000 claims 1
• 208000028017 Psychotic disease Diseases 0.000 claims 1
• 208000000810 Separation Anxiety Diseases 0.000 claims 1
• 201000008485 Wernicke-Korsakoff syndrome Diseases 0.000 claims 1
• 208000027418 Wounds and injury Diseases 0.000 claims 1
• 230000032683 aging Effects 0.000 claims 1
• 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 1
• 230000036506 anxiety Effects 0.000 claims 1
• 201000007201 aphasia Diseases 0.000 claims 1
• 208000029028 brain injury Diseases 0.000 claims 1
• 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
• 230000006378 damage Effects 0.000 claims 1
• 206010013461 dissociative amnesia Diseases 0.000 claims 1
• 208000018459 dissociative disease Diseases 0.000 claims 1
• 230000008482 dysregulation Effects 0.000 claims 1
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• 208000029364 generalized anxiety disease Diseases 0.000 claims 1
• 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 1
• 201000003723 learning disability Diseases 0.000 claims 1
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• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
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• 210000003205 muscle Anatomy 0.000 claims 1
• 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 claims 1
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• 230000008733 trauma Effects 0.000 claims 1