JPWO2020081819A5 - - Google Patents
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- Publication number
- JPWO2020081819A5 JPWO2020081819A5 JP2021521403A JP2021521403A JPWO2020081819A5 JP WO2020081819 A5 JPWO2020081819 A5 JP WO2020081819A5 JP 2021521403 A JP2021521403 A JP 2021521403A JP 2021521403 A JP2021521403 A JP 2021521403A JP WO2020081819 A5 JPWO2020081819 A5 JP WO2020081819A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- exogenous
- molecule
- population
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cells Anatomy 0.000 claims 63
- 229920002477 rna polymer Polymers 0.000 claims 22
- 230000004660 morphological change Effects 0.000 claims 17
- 108090000623 proteins and genes Proteins 0.000 claims 15
- 102000004169 proteins and genes Human genes 0.000 claims 15
- 229920001184 polypeptide Polymers 0.000 claims 14
- 229920003013 deoxyribonucleic acid Polymers 0.000 claims 13
- 150000007523 nucleic acids Chemical group 0.000 claims 10
- 229920001272 Exogenous DNA Polymers 0.000 claims 9
- 229920002521 Macromolecule Polymers 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 229920001850 Nucleic acid sequence Polymers 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 238000004422 calculation algorithm Methods 0.000 claims 3
- 238000010801 machine learning Methods 0.000 claims 3
- 238000001327 Förster resonance energy transfer Methods 0.000 claims 2
- 210000003463 Organelles Anatomy 0.000 claims 2
- 108010017070 Zinc Finger Nucleases Proteins 0.000 claims 2
- 239000000470 constituent Substances 0.000 claims 2
- 238000002372 labelling Methods 0.000 claims 2
- 230000001537 neural Effects 0.000 claims 2
- 230000004044 response Effects 0.000 claims 2
- 101700080605 NUC1 Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000001413 cellular Effects 0.000 claims 1
- 238000004163 cytometry Methods 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 230000004807 localization Effects 0.000 claims 1
- 238000007477 logistic regression Methods 0.000 claims 1
- 238000007481 next generation sequencing Methods 0.000 claims 1
- 101700006494 nucA Proteins 0.000 claims 1
- 230000037361 pathway Effects 0.000 claims 1
- 230000026447 protein localization Effects 0.000 claims 1
- 230000004850 protein–protein interaction Effects 0.000 claims 1
- 239000002096 quantum dot Substances 0.000 claims 1
- 238000007637 random forest analysis Methods 0.000 claims 1
- 238000000611 regression analysis Methods 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000002194 synthesizing Effects 0.000 claims 1
- 230000002123 temporal effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862747620P | 2018-10-18 | 2018-10-18 | |
| US62/747,620 | 2018-10-18 | ||
| US201962825524P | 2019-03-28 | 2019-03-28 | |
| US62/825,524 | 2019-03-28 | ||
| PCT/US2019/056743 WO2020081819A1 (en) | 2018-10-18 | 2019-10-17 | Methods and systems for target screening |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022512767A JP2022512767A (ja) | 2022-02-07 |
| JPWO2020081819A5 true JPWO2020081819A5 (ru) | 2022-10-26 |
Family
ID=70282999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521403A Pending JP2022512767A (ja) | 2018-10-18 | 2019-10-17 | 標的スクリーニングのための方法及びシステム |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20210310053A1 (ru) |
| EP (1) | EP3867374A4 (ru) |
| JP (1) | JP2022512767A (ru) |
| CN (1) | CN113195718A (ru) |
| WO (1) | WO2020081819A1 (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023042647A1 (ja) * | 2021-09-17 | 2023-03-23 | シンクサイト株式会社 | 分類モデル生成方法、粒子分類方法、コンピュータプログラム、及び情報処理装置 |
| WO2023042646A1 (ja) * | 2021-09-17 | 2023-03-23 | シンクサイト株式会社 | 分類モデル生成方法、粒子判定方法、コンピュータプログラム及び情報処理装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020026456A (ko) * | 2000-04-13 | 2002-04-10 | 에말파브 마크 아론 | 사상균에서 발현된 ｄｎａ 라이브러리의 고산출량 스크리닝 |
| WO2003048345A1 (en) * | 2001-12-07 | 2003-06-12 | Toolgen, Inc. | Phenotypic screen of chimeric proteins |
| US9157066B2 (en) * | 2005-12-13 | 2015-10-13 | The Trustees Of The University Of Pennsylvania | Transcriptome transfer produces cellular phenotype conversion |
| US20170052106A1 (en) * | 2014-04-28 | 2017-02-23 | The Broad Institute, Inc. | Method for label-free image cytometry |
| US20190218276A1 (en) * | 2016-03-21 | 2019-07-18 | The Broad Institute, Inc. | Methods for determining spatial and temporal gene expression dynamics in single cells |
| WO2018126205A1 (en) * | 2016-12-30 | 2018-07-05 | The Regents Of The University Of California | Methods for selection and generation of genome edited t cells |
-
2019
- 2019-10-17 CN CN201980083654.6A patent/CN113195718A/zh active Pending
- 2019-10-17 WO PCT/US2019/056743 patent/WO2020081819A1/en unknown
- 2019-10-17 JP JP2021521403A patent/JP2022512767A/ja active Pending
- 2019-10-17 EP EP19873817.1A patent/EP3867374A4/en active Pending
-
2021
- 2021-04-15 US US17/231,725 patent/US20210310053A1/en active Pending
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