JPWO2020061293A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020061293A5
JPWO2020061293A5 JP2021515616A JP2021515616A JPWO2020061293A5 JP WO2020061293 A5 JPWO2020061293 A5 JP WO2020061293A5 JP 2021515616 A JP2021515616 A JP 2021515616A JP 2021515616 A JP2021515616 A JP 2021515616A JP WO2020061293 A5 JPWO2020061293 A5 JP WO2020061293A5
Authority
JP
Japan
Prior art keywords
cancer
composition
prostate cancer
contrast agent
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021515616A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022501383A (ja
JP7429688B2 (ja
JP2022501383A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/051903 external-priority patent/WO2020061293A1/en
Publication of JP2022501383A publication Critical patent/JP2022501383A/ja
Publication of JPWO2020061293A5 publication Critical patent/JPWO2020061293A5/ja
Publication of JP2022501383A5 publication Critical patent/JP2022501383A5/ja
Priority to JP2023204832A priority Critical patent/JP7748438B2/ja
Application granted granted Critical
Publication of JP7429688B2 publication Critical patent/JP7429688B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021515616A 2018-09-21 2019-09-19 シールド剤およびそれらの使用 Active JP7429688B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023204832A JP7748438B2 (ja) 2018-09-21 2023-12-04 シールド剤およびそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862734690P 2018-09-21 2018-09-21
US62/734,690 2018-09-21
PCT/US2019/051903 WO2020061293A1 (en) 2018-09-21 2019-09-19 Shielding agents and their use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023204832A Division JP7748438B2 (ja) 2018-09-21 2023-12-04 シールド剤およびそれらの使用

Publications (4)

Publication Number Publication Date
JP2022501383A JP2022501383A (ja) 2022-01-06
JPWO2020061293A5 true JPWO2020061293A5 (https=) 2022-09-29
JP2022501383A5 JP2022501383A5 (https=) 2022-09-29
JP7429688B2 JP7429688B2 (ja) 2024-02-08

Family

ID=69887812

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021515616A Active JP7429688B2 (ja) 2018-09-21 2019-09-19 シールド剤およびそれらの使用
JP2023204832A Active JP7748438B2 (ja) 2018-09-21 2023-12-04 シールド剤およびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023204832A Active JP7748438B2 (ja) 2018-09-21 2023-12-04 シールド剤およびそれらの使用

Country Status (5)

Country Link
US (1) US20210323985A1 (https=)
EP (1) EP3853213A4 (https=)
JP (2) JP7429688B2 (https=)
CN (1) CN113166087B (https=)
WO (1) WO2020061293A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015011118B1 (pt) * 2012-11-15 2022-12-13 Endocyte, Inc Conjugado; composição farmacêutica; e uso de um conjugado
BR112016010927A2 (pt) 2013-11-14 2017-08-08 Endocyte Inc Conjugado de fórmula
US12208102B2 (en) 2018-04-17 2025-01-28 Endocyte, Inc. Methods of treating cancer
CN114096264B (zh) 2019-05-20 2025-03-14 因多塞特股份有限公司 制备psma缀合物的方法
CA3237590A1 (en) * 2021-11-09 2023-05-08 James Basilion Psma targeted conjugate compounds and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2847275T3 (es) * 2006-11-08 2021-08-02 Molecular Insight Pharm Inc Heterodímeros de ácido glutámico
EP4464384A3 (en) 2007-08-17 2025-01-08 Purdue Research Foundation Psma binding ligand-linker conjugates and methods for using
WO2012174136A1 (en) * 2011-06-15 2012-12-20 Cancer Targeted Technology Llc Chelated psma inhibitors
BR112015011118B1 (pt) * 2012-11-15 2022-12-13 Endocyte, Inc Conjugado; composição farmacêutica; e uso de um conjugado
LT4095130T (lt) * 2013-10-18 2024-04-25 Novartis Ag Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti
US9988407B2 (en) 2014-08-06 2018-06-05 The Johns Hopkins University Prodrugs of prostate specific membrane antigen (PSMA) inhibitor
AU2015315465B2 (en) 2014-09-08 2019-08-29 Molecular Insight Pharmaceuticals, Inc. Organ protection in PSMA-targeted radionuclide therapy of prostate cancer
SG11201909513QA (en) 2017-04-11 2019-11-28 Univ Johns Hopkins Prodrugs of 2-pmpa for healthy tissue protection during psma-targeted cancer imaging or radiotherapy

Similar Documents

Publication Publication Date Title
Altunay et al. HER2-directed antibodies, affibodies and nanobodies as drug-delivery vehicles in breast cancer with a specific focus on radioimmunotherapy and radioimmunoimaging
JP2022501383A5 (https=)
Song et al. Radioimmunotherapy of breast cancer metastases with α-particle emitter 225Ac: comparing efficacy with 213Bi and 90Y
DeNardo Radioimmunodetection and therapy of breast cancer
Maraveyas et al. Pharmacokinetics and toxicity of an yttrium‐90‐citc‐dtpa‐hmfg1 radioimmunoconjugate for intraperitoneal radioimmunotherapy of ovarian cancer
JP2010508292A5 (https=)
Allen Clinical trials of targeted alpha therapy for cancer
Rowlinson et al. Antibody-guided localization of intraperitoneal tumors following intraperitoneal or intravenous antibody administration
Loke et al. Dosimetric considerations in radioimmunotherapy and systemic radionuclide therapies: a review
JPWO2020061293A5 (https=)
Illidge et al. Radioimmunotherapy in follicular lymphoma
Grana et al. Radioimmunotherapy in advanced ovarian cancer: is there a role for pre-targeting with 90Y-biotin?
Li et al. The experimental study on the radioimmunotherapy of the nasopharyngeal carcinoma overexpressing HER2/neu in nude mice model with intratumoral injection of 188Re-herceptin
Buchsbaum Experimental radioimmunotherapy
Burvenich et al. Biodistribution and planar gamma camera imaging of 123I-and 131I-labeled F (ab′) 2 and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor
Chen et al. In vivo examination of 188Re (I)-tricarbonyl-labeled trastuzumab to target HER2-overexpressing breast cancer
Izard et al. An improved method for labeling monoclonal antibodies with samarium-153: use of the bifunctional chelate 2-(p-isothiocyanatobenzyl)-6-methyldiethylenetriaminepentaacetic acid
Dearling et al. Technological advances in radioimmunotherapy
Yoo et al. Small hepatocellular carcinoma: high dose internal radiation therapy with superselective intra-arterial injection of I-131-labeled Lipiodol
US20210236664A1 (en) Alpha particle formulations for treatment of solid tumors
Rogers et al. Intraperitoneal radioimmunotherapy with a humanized anti-TAG-72 (CC49) antibody with a deleted CH2 region
Riva et al. Radioimmunotherapy of CMS Malignant Gliomas by Direct Intralesional Injection of Specific 131| Radiolabeled Monoclonal Antibodies
Camacho et al. 177Lu-DOTA-Bevacizumab: Radioimmunotherapy agent for melanoma
Hauck et al. Enhanced tumour uptake of radiolabelled antibodies by hyperthermia: Part I: Timing of injection relative to hyperthermia
JP7239662B2 (ja) 複合体、造影剤、及びcxcr4関連疾患を治療又は診断するための医薬品