JPWO2020018975A5 - - Google Patents
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- JPWO2020018975A5 JPWO2020018975A5 JP2021502987A JP2021502987A JPWO2020018975A5 JP WO2020018975 A5 JPWO2020018975 A5 JP WO2020018975A5 JP 2021502987 A JP2021502987 A JP 2021502987A JP 2021502987 A JP2021502987 A JP 2021502987A JP WO2020018975 A5 JPWO2020018975 A5 JP WO2020018975A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- alkyl
- cycloalkyl
- halogen
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862701313P | 2018-07-20 | 2018-07-20 | |
| US62/701,313 | 2018-07-20 | ||
| PCT/US2019/042711 WO2020018975A1 (en) | 2018-07-20 | 2019-07-19 | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021532101A JP2021532101A (ja) | 2021-11-25 |
| JPWO2020018975A5 true JPWO2020018975A5 (ru) | 2022-07-25 |
| JP7320595B2 JP7320595B2 (ja) | 2023-08-03 |
Family
ID=67659954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021502987A Active JP7320595B2 (ja) | 2018-07-20 | 2019-07-19 | インターロイキン－１活性の阻害剤としてのスルホンイミドアミド化合物 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20210253596A1 (ru) |
| EP (1) | EP3823974A1 (ru) |
| JP (1) | JP7320595B2 (ru) |
| KR (1) | KR20210034596A (ru) |
| CN (1) | CN112513048A (ru) |
| AR (1) | AR115822A1 (ru) |
| AU (1) | AU2019306658A1 (ru) |
| BR (1) | BR112021001044A2 (ru) |
| CA (1) | CA3105521A1 (ru) |
| CL (1) | CL2021000153A1 (ru) |
| CO (1) | CO2021001530A2 (ru) |
| CR (1) | CR20210022A (ru) |
| IL (1) | IL279256A (ru) |
| MA (1) | MA53172A (ru) |
| MX (1) | MX2021000780A (ru) |
| PE (1) | PE20211811A1 (ru) |
| PH (1) | PH12021500005A1 (ru) |
| SG (1) | SG11202013062VA (ru) |
| TW (1) | TWI825134B (ru) |
| WO (1) | WO2020018975A1 (ru) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20190356A (es) | 2017-01-23 | 2019-11-20 | Genentech Inc | Compuestos químicos como inhibidores de la actividad de la interleuquina-1 |
| EP3692020A1 (en) | 2017-10-03 | 2020-08-12 | Inflazome Limited | Novel compounds |
| CN112437683A (zh) | 2018-07-20 | 2021-03-02 | 豪夫迈·罗氏有限公司 | 用作白细胞介素-1 活性抑制剂的磺酰脲类化合物 |
| EP3880659B1 (en) * | 2018-11-16 | 2024-01-03 | Novartis AG | Compounds and compositions for treating conditions associated with nlrp activity |
| EP3914585A1 (en) * | 2019-01-23 | 2021-12-01 | Novartis AG | Sulfonimidamide compounds and compositions for treating conditions associated with nlrp activity |
| US20220378801A1 (en) | 2019-06-21 | 2022-12-01 | Ac Immune Sa | Novel compounds |
| WO2021002887A1 (en) * | 2019-07-02 | 2021-01-07 | Novartis Inflammasome Research, Inc. | Gut-targeted nlrp3 antagonists and their use in therapy |
| BR112022009209A2 (pt) * | 2019-11-12 | 2022-07-26 | Chengdu Baiyu Pharmaceutical Co Ltd | Derivado de amida e método de preparação e uso do mesmo na medicina |
| CA3167023A1 (en) * | 2020-01-22 | 2021-07-29 | F. Hoffmann-La Roche Ag | Sulfonimidamide compounds as nlrp3 modulators |
| JP2023518044A (ja) | 2020-03-16 | 2023-04-27 | ズーマゲン バイオサイエンシーズ エルティーディー | Ｎｌｒｐ３モジュレーター |
| BR112022020807A2 (pt) | 2020-04-15 | 2022-11-29 | Janssen Pharmaceutica Nv | Pirazolo[1,5-d][1,2,4]triazina-5(4h)-acetamidas como inibidores da trajetória de inflamassoma de nlrp3 |
| KR20230002652A (ko) | 2020-04-15 | 2023-01-05 | 얀센 파마슈티카 엔.브이. | NLRP3 인플라마좀 경로의 저해제로서의 피롤로[1,2-d][1,2,4]트리아진-2-일-아세트아미드 |
| AU2021260115A1 (en) | 2020-04-23 | 2023-01-05 | Janssen Pharmaceutica Nv | Tricyclic compounds as inhibitors of NLRP3 |
| MX2022013637A (es) | 2020-04-30 | 2022-11-16 | Janssen Pharmaceutica Nv | Nuevos compuestos de triazinoindol. |
| WO2021239885A1 (en) | 2020-05-28 | 2021-12-02 | Janssen Pharmaceutica Nv | Compounds |
| MX2022014709A (es) | 2020-06-19 | 2022-12-16 | Ac Immune Sa | Derivados de dihidrooxazol y tiourea que modulan la ruta del inflamasoma de la proteina 3 que contiene el dominio pirina de la familia del receptor similar al dominio de oligomerizacion de union a nucleotido (nlrp3). |
| EP3974415A1 (en) | 2020-09-24 | 2022-03-30 | Janssen Pharmaceutica NV | Nlrp3 modulators |
| KR20230074528A (ko) | 2020-09-24 | 2023-05-30 | 얀센 파마슈티카 엔.브이. | 신규 화합물 |
| CN114539256B (zh) * | 2020-11-20 | 2024-02-02 | 上海拓界生物医药科技有限公司 | 三环化合物及其医药用途 |
| CA3208414A1 (en) | 2021-03-04 | 2022-09-09 | Daniel Oehlrich | 4-amino-6-oxo-pyridazine derivatives modulating nlrp3 |
| JP2024508017A (ja) | 2021-03-04 | 2024-02-21 | ヤンセン ファーマシューティカ エヌ．ベー． | Ｎｌｒｐ３を調節する４－アルコキシ－６－オキソ－ピリダジン誘導体 |
| EP4330235A1 (en) | 2021-04-29 | 2024-03-06 | JANSSEN Pharmaceutica NV | Phthalazinone derivatives as nlrp3 inflammasome inhibitors |
| TW202246230A (zh) * | 2021-05-10 | 2022-12-01 | 大陸商成都百裕製藥股份有限公司 | 醯胺衍生物及其應用 |
| CN116917282A (zh) * | 2021-05-10 | 2023-10-20 | 成都百裕制药股份有限公司 | 酰胺衍生物及其应用 |
| AU2022301461A1 (en) | 2021-07-01 | 2024-02-15 | Janssen Pharmaceutica Nv | 5-oxo-pyrido[2,3-d]pyridazin-6(5h)-yl acetamides |
| CR20240023A (es) * | 2021-07-19 | 2024-02-13 | Genentech Inc | Compuestos de sulfonimidamida y usos de los mismos |
| WO2023118521A1 (en) | 2021-12-22 | 2023-06-29 | Ac Immune Sa | Dihydro-oxazol derivative compounds |
| WO2024010772A1 (en) * | 2022-07-06 | 2024-01-11 | Kodiak Sciences Inc. | Nlrp3 inhibitors |
| US20240034735A1 (en) | 2022-07-14 | 2024-02-01 | Ac Immune Sa | Novel compounds |
| US20240101563A1 (en) | 2022-07-28 | 2024-03-28 | Ac Immune Sa | Novel compounds |
| WO2024064245A1 (en) | 2022-09-23 | 2024-03-28 | Merck Sharp & Dohme Llc | Phthalazine derivatives useful as inhibitors of nod-like receptor protein 3 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3888749A1 (en) * | 2015-02-16 | 2021-10-06 | The University of Queensland | Sulfonylureas and related compounds and use of same |
| CR20190356A (es) * | 2017-01-23 | 2019-11-20 | Genentech Inc | Compuestos químicos como inhibidores de la actividad de la interleuquina-1 |
| WO2019023147A1 (en) * | 2017-07-24 | 2019-01-31 | IFM Tre, Inc. | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH NLRP ACTIVITY |
| EP3692020A1 (en) * | 2017-10-03 | 2020-08-12 | Inflazome Limited | Novel compounds |
-
2019
- 2019-07-19 AU AU2019306658A patent/AU2019306658A1/en active Pending
- 2019-07-19 PE PE2021000082A patent/PE20211811A1/es unknown
- 2019-07-19 EP EP19753515.6A patent/EP3823974A1/en active Pending
- 2019-07-19 JP JP2021502987A patent/JP7320595B2/ja active Active
- 2019-07-19 WO PCT/US2019/042711 patent/WO2020018975A1/en unknown
- 2019-07-19 KR KR1020217002210A patent/KR20210034596A/ko unknown
- 2019-07-19 CA CA3105521A patent/CA3105521A1/en active Pending
- 2019-07-19 CR CR20210022A patent/CR20210022A/es unknown
- 2019-07-19 CN CN201980048375.6A patent/CN112513048A/zh active Pending
- 2019-07-19 SG SG11202013062VA patent/SG11202013062VA/en unknown
- 2019-07-19 MA MA053172A patent/MA53172A/fr unknown
- 2019-07-19 BR BR112021001044-0A patent/BR112021001044A2/pt unknown
- 2019-07-19 MX MX2021000780A patent/MX2021000780A/es unknown
- 2019-07-22 AR ARP190102055A patent/AR115822A1/es unknown
- 2019-07-22 TW TW108125886A patent/TWI825134B/zh active
-
2020
- 2020-12-07 IL IL279256A patent/IL279256A/en unknown
-
2021
- 2021-01-15 US US17/150,349 patent/US20210253596A1/en active Pending
- 2021-01-19 PH PH12021500005A patent/PH12021500005A1/en unknown
- 2021-01-19 CL CL2021000153A patent/CL2021000153A1/es unknown
- 2021-02-10 CO CONC2021/0001530A patent/CO2021001530A2/es unknown
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