JPWO2019222657A5 - - Google Patents
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- Publication number
- JPWO2019222657A5 JPWO2019222657A5 JP2020564491A JP2020564491A JPWO2019222657A5 JP WO2019222657 A5 JPWO2019222657 A5 JP WO2019222657A5 JP 2020564491 A JP2020564491 A JP 2020564491A JP 2020564491 A JP2020564491 A JP 2020564491A JP WO2019222657 A5 JPWO2019222657 A5 JP WO2019222657A5
- Authority
- JP
- Japan
- Prior art keywords
- cfdna
- fragmentation profile
- mammal
- cancer
- window
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000013467 fragmentation Methods 0.000 claims 25
- 238000006062 fragmentation reaction Methods 0.000 claims 25
- 241000124008 Mammalia Species 0.000 claims 17
- 238000000034 method Methods 0.000 claims 13
- 239000012634 fragment Substances 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 238000012163 sequencing technique Methods 0.000 claims 2
- 238000013507 mapping Methods 0.000 claims 1
- 238000012070 whole genome sequencing analysis Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024032720A JP2024069295A (ja) | 2018-05-18 | 2024-03-05 | 癌を査定および／または処置するためのセルフリーｄｎａ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862673516P | 2018-05-18 | 2018-05-18 | |
| US62/673,516 | 2018-05-18 | ||
| US201962795900P | 2019-01-23 | 2019-01-23 | |
| US62/795,900 | 2019-01-23 | ||
| PCT/US2019/032914 WO2019222657A1 (fr) | 2018-05-18 | 2019-05-17 | Adn acellulaire pour évaluer et/ou traiter le cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024032720A Division JP2024069295A (ja) | 2018-05-18 | 2024-03-05 | 癌を査定および／または処置するためのセルフリーｄｎａ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525069A JP2021525069A (ja) | 2021-09-24 |
| JPWO2019222657A5 true JPWO2019222657A5 (fr) | 2022-05-24 |
| JP7531217B2 JP7531217B2 (ja) | 2024-08-09 |
Family
ID=68541029
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564491A Active JP7531217B2 (ja) | 2018-05-18 | 2019-05-17 | 癌を査定および／または処置するためのセルフリーｄｎａ |
| JP2024032720A Pending JP2024069295A (ja) | 2018-05-18 | 2024-03-05 | 癌を査定および／または処置するためのセルフリーｄｎａ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024032720A Pending JP2024069295A (ja) | 2018-05-18 | 2024-03-05 | 癌を査定および／または処置するためのセルフリーｄｎａ |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20210198747A1 (fr) |
| EP (1) | EP3794348A4 (fr) |
| JP (2) | JP7531217B2 (fr) |
| KR (1) | KR20210045953A (fr) |
| CN (1) | CN112805563A (fr) |
| AU (1) | AU2019269679A1 (fr) |
| BR (1) | BR112020023587A2 (fr) |
| CA (1) | CA3100345A1 (fr) |
| WO (1) | WO2019222657A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3794348A4 (fr) | 2018-05-18 | 2022-03-09 | The Johns Hopkins University | Adn acellulaire pour évaluer et/ou traiter le cancer |
| GB201818159D0 (en) * | 2018-11-07 | 2018-12-19 | Cancer Research Tech Ltd | Enhanced detection of target dna by fragment size analysis |
| IL293681A (en) * | 2019-12-19 | 2022-08-01 | Cadex Genomics Corp | A multiplexed assay using variable fragment size to detect cancer-specific cell-free DNA |
| CN111088303A (zh) * | 2020-01-08 | 2020-05-01 | 杭州瑞普基因科技有限公司 | 模拟血浆cfDNA及制备方法和测序文库的构建方法 |
| WO2021188889A1 (fr) * | 2020-03-20 | 2021-09-23 | Mission Bio, Inc. | Flux de travail unicellulaire pour l'amplification du génome entier |
| CA3173453A1 (fr) * | 2020-03-26 | 2021-09-30 | Wai Yi Tsui | Systemes et procedes pour distinguer des mutations pathologiques de mutations hematopoietiques clonales dans un adn libre circulant par analyse de taille de fragment |
| CN115715330A (zh) * | 2020-05-12 | 2023-02-24 | 小利兰·斯坦福大学托管委员会 | 用于从无细胞dna中推断基因表达和起源组织的系统和方法 |
| EP4169025A4 (fr) * | 2020-06-22 | 2024-07-10 | Childrens Hospital Med Ct | Caractérisation de novo de points chauds de fragmentation d'adn acellulaire chez des sujets sains et cancéreux à un stade précoce |
| KR20220071122A (ko) * | 2020-11-23 | 2022-05-31 | 주식회사 지씨지놈 | 핵산 길이 비를 이용한 암 진단 및 예후예측 방법 |
| CA3214391A1 (fr) * | 2021-04-08 | 2022-10-13 | Gavin HA | Procede d'analyse de donnees de sequence d'adn acellulaire pour examiner la protection du nucleosome et l'accessibilite de la chromatine |
| CA3214321A1 (fr) * | 2021-04-08 | 2022-10-13 | Nicholas C. Dracopoli | Methode de detection de cancer a l'aide de profils de fragmentation d'adn acellulaire a l'echelle du genome |
| KR20220160806A (ko) | 2021-05-28 | 2022-12-06 | 주식회사 지씨지놈 | 세포유리 핵산단편 말단 서열 모티프 빈도 및 크기를 이용한 암 진단 및 암 종 예측방법 |
| KR20230059423A (ko) | 2021-10-26 | 2023-05-03 | 주식회사 지씨지놈 | 메틸화된 무세포 핵산을 이용한 암 진단 및 암 종 예측방법 |
| KR20230064172A (ko) | 2021-11-03 | 2023-05-10 | 주식회사 지씨지놈 | 세포유리 핵산단편 위치별 서열 빈도 및 크기를 이용한 암 진단 방법 |
| WO2023200404A2 (fr) * | 2022-04-13 | 2023-10-19 | Lucence Life Sciences Pte. Ltd. | Procédé de détermination de rapport de taille de fragment et de distribution de taille de fragment d'adncf |
| WO2023220414A1 (fr) * | 2022-05-12 | 2023-11-16 | Delfi Diagnostics, Inc. | Utilisation de fragments d'adn libre circulant dans l'évaluation diagnostique de patients présentant des signes et des symptômes suggérant un cancer |
| CN117551767A (zh) * | 2022-09-29 | 2024-02-13 | 南京医科大学 | 一种cfDNA片段特征组合在预测癌症中的应用 |
| KR20240051739A (ko) * | 2022-10-13 | 2024-04-22 | 인하대학교 산학협력단 | cfDNA의 구조 변이 서열 검출을 통한 미세잔존질환 진단 방법 |
| CN118028462A (zh) * | 2022-11-02 | 2024-05-14 | 深圳湾实验室 | 一种泛癌种血液诊断标志物及其应用 |
| WO2024098073A1 (fr) * | 2022-11-06 | 2024-05-10 | The Johns Hopkins University | Détection du cancer du foie à l'aide d'une fragmentation d'adn acellulaire |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006251937A1 (en) | 2005-05-27 | 2006-11-30 | John Wayne Cancer Institute | Use of free circulating DNA for diagnosis, prognosis, and treatment of cancer |
| PL3214091T3 (pl) | 2010-12-09 | 2019-03-29 | The Trustees Of The University Of Pennsylvania | Zastosowanie komórek T modyfikowanych chimerycznymi receptorami antygenowymi do leczenia nowotworów |
| ES2791716T3 (es) | 2010-12-14 | 2020-11-05 | Univ Maryland | Células T que expresan al receptor de antígeno quimérico antietiqueta universal y métodos para el tratamiento del cáncer |
| EP2697397B1 (fr) | 2011-04-15 | 2017-04-05 | The Johns Hopkins University | Système de séquençage sûr |
| EP2794907B2 (fr) * | 2011-12-21 | 2022-11-23 | Myriad Genetics, Inc. | Procédés et matériaux pour évaluer la perte d'hétérozygotie |
| US8904664B2 (en) | 2012-08-15 | 2014-12-09 | Mimedx Group, Inc. | Dehydration device and methods for drying biological materials |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| US10865451B2 (en) | 2013-06-11 | 2020-12-15 | Dana-Farber Cancer Institute, Inc. | Non-invasive blood based monitoring of genomic alterations in cancer |
| WO2015048535A1 (fr) | 2013-09-27 | 2015-04-02 | Natera, Inc. | Normes d'essais pour diagnostics prénataux |
| JP2017522908A (ja) * | 2014-07-25 | 2017-08-17 | ユニヴァーシティ オブ ワシントン | セルフリーｄｎａを生じる組織及び／又は細胞タイプを決定する方法、並びにそれを用いて疾患又は異常を識別する方法 |
| DK3213084T4 (da) * | 2014-10-29 | 2024-03-18 | Belgian Volition Sprl | Fremgangsmåde til berigelse af cirkulerende tumor dna |
| MA40939A (fr) * | 2014-12-12 | 2017-10-18 | Verinata Health Inc | Utilisation de la taille de fragments d'adn acellulaire pour déterminer les variations du nombre de copies |
| US10364467B2 (en) * | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| AU2016295616B2 (en) * | 2015-07-23 | 2022-06-02 | The Chinese University Of Hong Kong | Analysis of fragmentation patterns of cell-free DNA |
| WO2017190067A1 (fr) * | 2016-04-28 | 2017-11-02 | Impact Genomics, Inc. | Procédés d'évaluation et de surveillance d'une charge tumorale |
| WO2018027176A1 (fr) * | 2016-08-05 | 2018-02-08 | The Broad Institute, Inc. | Procédés pour la caractérisation génomique |
| US11168356B2 (en) * | 2017-11-02 | 2021-11-09 | The Chinese University Of Hong Kong | Using nucleic acid size range for noninvasive cancer detection |
| US20190352695A1 (en) * | 2018-01-10 | 2019-11-21 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| EP3794348A4 (fr) | 2018-05-18 | 2022-03-09 | The Johns Hopkins University | Adn acellulaire pour évaluer et/ou traiter le cancer |
-
2019
- 2019-05-17 EP EP19803533.9A patent/EP3794348A4/fr active Pending
- 2019-05-17 WO PCT/US2019/032914 patent/WO2019222657A1/fr active Application Filing
- 2019-05-17 US US17/056,726 patent/US20210198747A1/en active Pending
- 2019-05-17 AU AU2019269679A patent/AU2019269679A1/en active Pending
- 2019-05-17 JP JP2020564491A patent/JP7531217B2/ja active Active
- 2019-05-17 BR BR112020023587-3A patent/BR112020023587A2/pt unknown
- 2019-05-17 CN CN201980047828.3A patent/CN112805563A/zh active Pending
- 2019-05-17 CA CA3100345A patent/CA3100345A1/fr active Pending
- 2019-05-17 KR KR1020207036527A patent/KR20210045953A/ko unknown
- 2019-12-30 US US16/730,938 patent/US10982279B2/en active Active
- 2019-12-30 US US16/730,949 patent/US10975431B2/en active Active
-
2021
- 2021-03-17 US US17/204,892 patent/US20210254152A1/en active Pending
-
2022
- 2022-06-17 US US17/842,893 patent/US20220325343A1/en active Pending
-
2024
- 2024-03-05 JP JP2024032720A patent/JP2024069295A/ja active Pending
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