JPWO2019176822A1 - Medical equipment - Google Patents

Abstract

The medical device (10) includes a plurality of electrodes (12) arranged on the body surface of a living body, and a controller (18) that supplies electric pulses to the plurality of electrodes (12). The plurality of electrodes (12) constitute a pair of generation electrodes (20) that generate hydrogen peroxide in the body at the position where the cathode (22) is arranged by supplying an electric pulse. Further, the plurality of electrodes (12) are arranged around the cathode (22), and by supplying electric pulses of different frequencies, interference is generated at a position overlapping the cathode (22) in a plan view. It constitutes the electrode (30).

Description

The present invention relates to a medical device that produces hydrogen peroxide by electrical stimulation to promote treatment of a living body.

In recent years, attention has been focused on techniques for promoting treatment using hydrogen peroxide for various symptoms of a living body. Hydrogen peroxide is usually administered to the living body by infusion, but in transvascular administration, the amount of hydrogen peroxide that reaches the treatment site is reduced because the catalase enzyme present in the living body metabolizes the hydrogen peroxide. , Long-term treatment (restraint) is required.

In addition to infusion therapy, a method has also been devised in which hydrogen peroxide is generated in the living body by applying electrical stimulation to the living body and the hydrogen peroxide is used. For example, US Pat. No. 5,458,627 states that in bone regeneration treatment, hydrogen peroxide is generated near the cathode by the electrochemical reaction of oxygen and water in the living body by applying electrical stimulation to the treatment site. A technique for using hydrogen peroxide for bone regeneration is disclosed.

By the way, in the medical device disclosed in US Pat. No. 5,458,627, conditions for electrical stimulation are set based on the oxygen concentration and pH in the living body, and hydrogen peroxide is applied to the living body based on these conditions. The amount of production is adjusted. However, in this configuration, it is difficult to grasp the accurate state unless a sensor for measuring oxygen concentration and pH is inserted into the living body, and by inserting the sensor into the living body, a doctor's procedure is required and the living body is required. Invasion of the device will increase, and it will also increase the cost of the device.

In addition, in order to enhance non-invasiveness to the living body, it is conceivable to arrange a pair of electrodes on the body surface, but in this case, a large amount of hydrogen peroxide generated by electrical stimulation is generated subcutaneously. Therefore, in the treatment of the inner part of the body, there is a problem that it is difficult to sufficiently supply hydrogen peroxide and it is difficult to apply it to various treatments.

The present invention has been made in view of the above circumstances, and the treatment is more effective by appropriately managing hydrogen peroxide generated in the living body by electrical stimulation at low invasiveness and low cost. The purpose is to provide medical devices that can be promoted.

In order to achieve the above object, the medical device according to the present invention includes a plurality of electrodes arranged on the body surface of a living body, and an electric pulse supply unit that supplies electric pulses to the plurality of electrodes. The plurality of electrodes form a pair of generation electrodes that generate hydrogen peroxide in the body at the position where the cathode is arranged by supplying the electric pulse, and are arranged around the cathode to supply the electric pulse having different frequencies. Therefore, it is possible to construct a plurality of pairs of interference electrodes that generate interference low frequencies at positions overlapping the cathode in a plan view.

In this case, the electric pulse supply unit has a frequency of 1000 Hz or more for each of the electric pulses supplied to the plurality of pairs of interference electrodes, and the first pair electrode and the second pair of the plurality of pairs of interference electrodes. The difference in frequency of the electric pulses of the counter electrode is preferably 100 Hz or less.

Further, the pair of generation electrodes and the plurality of pairs of interference electrodes may be different electrodes from each other.

Alternatively, the anode of the pair of generation electrodes may also serve as one of the plurality of pairs of interference electrodes.

Further, the electric pulse supply unit supplies the electric pulse having a generation frequency for generating hydrogen peroxide to the pair of generation electrodes to generate the hydrogen peroxide, and then generates the interference low frequency. It is preferable that the electric pulses having different frequencies are supplied to each of the plurality of pairs of interference electrodes.

Alternatively, the electric pulse supply unit supplies the electric pulse having a generation frequency for generating the hydrogen peroxide to the pair of generation electrodes to generate the hydrogen peroxide, while the interference is low. The electric pulses having different frequencies that generate frequencies may be supplied to each of the plurality of pairs of interference electrodes.

Then, the medical device may have one pad in which the cathodes of the pair of generation electrodes are arranged at the center positions of the electrodes of the plurality of pairs of interference electrodes.

According to the present invention, a medical device has a pair of generation electrodes and a plurality of pairs of interference electrodes to satisfactorily control the production of hydrogen peroxide and the flow of hydrogen peroxide in a living body. Can be done. That is, the pair of generation electrodes generate hydrogen peroxide near the position where the cathode is arranged by supplying an electric pulse, and increase the concentration of hydrogen peroxide at that position. On the other hand, a plurality of pairs of interference electrodes generate an interference low frequency at a position overlapping the cathode by supplying an electric pulse, thereby satisfactorily contracting the muscle (living tissue) at this position and promoting the delivery of hydrogen peroxide. Can be done. That is, it is possible to increase the concentration of hydrogen peroxide in the treated area as compared with the infusion therapy, and the treatment with hydrogen peroxide can be promoted in a short time. Moreover, the plurality of electrodes are non-invasively arranged on the body surface and do not require a doctor's procedure. In addition, medical devices can reduce the occurrence of tissue inflammation and damage due to the accumulation of a large amount of hydrogen peroxide near the position of the cathode, and after moving the hydrogen peroxide, the hydrogen peroxide is again used. It becomes possible to generate. Therefore, the production efficiency of hydrogen peroxide can be increased.

It is explanatory drawing which shows schematic the whole structure of the medical device which concerns on one Embodiment of this invention. FIG. 2A is a first explanatory diagram illustrating the principle of hydrogen peroxide production by the electrodes. FIG. 2B is a second explanatory diagram illustrating the principle of hydrogen peroxide production by the electrodes. FIG. 3A is a flowchart showing a first processing flow in the use of the medical device. FIG. 3B is a flowchart showing a second processing flow in the use of the medical device. FIG. 4A is an explanatory diagram schematically showing an operating state of a pair of generation electrodes arranged in a living body. FIG. 4B is an explanatory diagram schematically showing an operating state of a plurality of pairs of interference electrodes arranged in a living body. FIG. 5A is a plan view showing an attached body of the medical device according to the first modification. FIG. 5B is a plan view showing the first and second wearing bodies of the medical device according to the second modification.

Hereinafter, preferred embodiments of the present invention will be given and described in detail with reference to the accompanying drawings.

As shown in FIG. 1, the medical device 10 according to the embodiment of the present invention is a device that applies electrical stimulation to a living _{body to generate hydrogen peroxide (H 2} O ₂ ) in the body. The hydrogen hydrogen produced in the body reacts with other molecules to oxidize and reduce living tissues and various other substances, thereby promoting sugar metabolism, increasing ATP production, removing bacteria and viruses, and so on. Activation of monocyte macrophages, helper T cells, reduction of blood cholesterol and triglyceride, increase of alveolar blood flow to promote oxidation, necrosis, removal of damaged tissue, production of hormones such as progesterone and thyroxin Effects such as promotion can be expected.

Therefore, hydrogen peroxide can be used for various treatments. Cases of treatment include respiratory diseases (COPD, bronchial asthma, pulmonary emphysema), viral infections (simple herpes, herpes zoster, HIV, influenza, EB virus, cytomegalovirus), bacterial infections, fungi, candida infections, pieces. Headache, swarm headache, vascular headache, temporal arteritis, cerebrovascular disease, Alzheimer's disease, Parkinson's disease, cardiovascular disease (angina, arrhythmia, peripheral arterial disease), type 2 diabetes, multiple sclerosis, chronic joints Examples include rheumatism, erythematosus, metastatic cancer, malignant lymphoma, neuroblastoma, and chronic fatigue syndrome.

Hereinafter, an example in which the medical device 10 is applied to the treatment of a user (living body) of type 2 diabetes will be described in detail, but the medical device 10 according to the present invention is used for various treatments by appropriately modifying it. Of course you can get it.

The medical device 10 includes a wearable body 14 that is worn by the user, and a controller 18 that is connected to the wearable body 14 and controls the supply of electrical stimulation and the like. The wearing body 14 is provided with a plurality of electrodes 12 arranged so as to face the body surface of the user in the wearing state. The plurality of electrodes 12 include a pair of generation electrodes 20 that generate hydrogen peroxide by supplying electric pulses, and a plurality of pairs of interference electrodes 30 that generate interference low frequencies by supplying electric pulses of different frequencies. ..

Here, in order to facilitate understanding of the present invention, the principle of hydrogen peroxide production using a pair of generation electrodes 20 will be described with reference to FIGS. 2A and 2B. As shown in FIG. 2A, in the use of the medical device 10, the cathode 22 of the pair of generation electrodes 20 is placed in a position close to or in contact with the treatment site on the body surface of the user. The anode 24 is provided on the mounting body 14 at a position relatively close to the cathode 22 (see also FIG. 1), and is placed on the body surface together with the cathode 22 in the mounted state.

Then, the controller 18 supplies an electric pulse having a predetermined frequency to the cathode 22 and the anode 24 as an electric stimulus. The electric pulse energizes between the cathode 22 and the anode 24 via the user's body. That is, electrons (e ⁻ ) having oscillating energy are supplied to the body. A large amount of oxygen (O ₂ ) and water (H ₂ O) are present in living tissues, and some of the electrons emitted from the cathode 22 chemically react with these oxygen and water. Specifically, the following reaction occurs in the vicinity of the cathode 22 (see also FIG. 2B).
O ₂ + 2H ₂ O + 4e ⁻ → 4OH ⁻

At this time, hydrogen peroxide (H ₂ O ₂ ) is generated as a secondary product. That is, the cathode 22 and the anode 24 arranged on the body surface can generate hydrogen peroxide in the body non-invasively by applying an electric pulse.

The medical device 10 according to the present embodiment is configured to appropriately control the production location and the production amount of hydrogen peroxide generated by the above principle. Hereinafter, each configuration of the medical device 10 will be specifically described.

Returning to FIG. 1, the wearing body 14 of the medical device 10 has a pad 16 configured to be attached to the body surface. The pad 16 is made of a sheet having appropriate flexibility and rigidity, and has a square shape with rounded corners in a plan view. As described above, the medical device 10 is configured to be used for the treatment of diabetes, and the pad 16 is designed to have a planar shape capable of sufficiently covering a portion where visceral fat is accumulated (for example, the abdomen).

A sticking surface portion 16a that can be stuck to the user is provided on one surface of the pad 16. In addition, in FIG. 1, the surface which the pad 16 faces from the opposite direction of the sticking surface portion 16a is shown. An adhesive layer that can be attached to a living body is applied to the attachment surface portion 16a. For example, a gel pressure-sensitive adhesive, a hydrophilic colloid, a silicon-based adhesive, an acrylic pressure-sensitive adhesive, or the like may be applied to the adhesive layer. Further, the wearing body 14 is not limited to the configuration of only the pad 16, for example, the other surface of the pad 16 is fixed to a belt (not shown), and the belt is wound around the user's body surface to form the pad 16. It may be configured to be positioned and fixed at the treatment site of the user.

The plurality of electrodes 12 (a pair of generation electrodes 20 and a plurality of pairs of interference electrodes 30) are arranged on one side on which the sticking surface portion 16a is formed. For example, the sticking surface portion 16a of the pad 16 is formed of a plurality of layers, and a plurality of electrodes 12 are arranged between the layers. As a result, the plurality of electrodes 12 are not exposed on the sticking surface portion 16a. It is preferable that the sticking surface portion 16a is formed with a printing portion indicating the accommodation positions of the plurality of electrodes 12. Further, the plurality of electrodes 12 may be attached to the attachment surface portion 16a and exposed to the outside.

The pair of generation electrodes 20 conduct an electric pulse having a predetermined wavelength between the cathode 22 and the anode 24 through the body. The cathode 22 and the anode 24 are plate-shaped, foil-shaped, or thin rod-shaped conductors made of a metal material such as silver or titanium or carbon. The cathode 22 and the anode 24 are formed in a perfect circular shape having a predetermined diameter, and are electrically connected to the controller 18 via the electric wiring 19.

For example, in FIG. 1, the cathode 22 is arranged at the center position in the vertical direction of the pad 16 and to the left of the center position in the width direction of the pad 16. On the other hand, the anode 24 is arranged below the vertical center position of the pad 16 and to the right of the width direction center position. The distance between the cathode 22 and the anode 24 may be set to be about the same as or slightly longer than the distance between the plurality of pairs of interference electrodes 30 described later so that the electric pulse reaches the living tissue deeper than the subcutaneous tissue.

If the cathode 22 is located at the center of a plurality of pairs of interference electrodes 30, the arrangement position on the pad 16 is not particularly limited. Further, the arrangement position of the anode 24 may be any as long as it can be energized with the cathode 22, and can be freely designed regardless of the arrangement of the interference electrode 30.

The plurality of pairs of interference electrodes 30 include a first pair electrode 32 arranged so that the cathode 22 is located at the center, and a second pair electrode 34. The first pair electrode 32 has a first positive electrode 32a and a first negative electrode 32b, and the second pair electrode 34 has a second positive electrode 34a and a second negative electrode 34b. That is, the plurality of pairs of interference electrodes 30 are composed of four electrodes 32a, 32b, 34a, and 34b. The four electrodes 32a, 32b, 34a, and 34b are electrically connected to the controller 18 via the electrical wiring 19, respectively.

The four electrodes 32a, 32b, 34a, 34b can be made of the same material as the pair of generation electrodes 20. Further, the four electrodes 32a, 32b, 34a, and 34b are formed in a perfect circular shape having the same shape and the same dimensions as each other. For example, the four electrodes 32a, 32b, 34a, and 34b are designed to have dimensions smaller than the dimensions of the cathode 22 and the anode 24 of the generation electrode 20, thereby using the difference between the generation electrode 20 and the interference electrode 30. It can be easily recognized by a person.

More specifically, in the plan view shown in FIG. 1, the first positive electrode 32a is arranged on the left side and the upper side of the pad 16, and the first negative electrode 32b is on the right side and on the right side of the center position in the width direction of the pad 16. It is located on the lower side. On the other hand, the second positive electrode 34a is arranged on the right side and upper side of the center position in the width direction of the pad 16, and the second negative electrode 34b is arranged on the left side and lower side of the pad 16.

The cathode 22 and the first pair electrode 32 are aligned so as to be linear and inclined with respect to the longitudinal direction of the pad 16. Further, the cathode 22 and the second pair electrode 34 are also arranged so as to be linear and inclined with respect to the longitudinal direction of the pad 16. The line segment L1 connecting the first pair electrode 32 and the line segment L2 connecting the second pair electrode 34 are orthogonal to each other (see also FIG. 4B). That is, the four electrodes 32a, 32b, 34a, 34b are located at the respective apex of the square shape drawn by virtually connecting the four electrodes 32a, 32b, 34a, 34b. The anode 24 of the pair of generation electrodes 20 is arranged on the right side of the first negative electrode 32b and the second positive electrode 34a.

Electric pulses having different frequencies are supplied from the controller 18 (electric pulse supply unit) to the first pair electrode 32 and the second pair electrode 34. As a result, the interference electrode 30 generates an interference low frequency at a position overlapping the cathode 22 in a plan view. This low interference frequency acts on muscles (living tissues) located deep from the body surface of the living body to induce muscle contraction.

Specifically, the controller 18 supplies an electric pulse having a medium frequency of about 1 kHz or more and about 10 kHz or less and a frequency difference of 100 Hz or less to each of the first and second counter electrodes 32 and 34. For example, the controller 18 supplies a 5000 Hz electrical pulse to the first pair electrode 32 while supplying a 5010 Hz electrical pulse to the second pair electrode 34. That is, in the body, an electric pulse of 5000 Hz flows along the line segment L1 of the first pair electrode 32, and an electric pulse of 5010 Hz flows along the line segment L2 of the second pair electrode 34. As a result, an interference low frequency of 10 Hz, which is a frequency difference, is generated at the intersection of the line segments L1 and L2.

Since this interference low frequency includes a medium frequency of 5000 Hz even if it is apparently low frequency, the electric pulse can reach a deeper position from the body surface. Further, since the medium frequency electric pulse has a low skin resistance value, it is possible to make it difficult to feel the pain of energization, so that the current output can be increased.

The controller 18 of the medical device 10 is configured as an electric pulse supply unit that supplies electric pulses to a plurality of electrodes 12. Inside the controller 18, a generation pulse supply unit 40 that supplies an electric pulse of a generation frequency to the generation electrode 20 and an interference device that supplies an electric pulse of an interference frequency to a plurality of pairs of interference electrodes 30. A pulse supply unit 42 is provided. Further, the controller 18 includes a control main body 44 that controls the operations of the supply units 40 and 42, and a battery 46 that can supply electric power to each unit.

Here, it is preferable that the controller 18 of the medical device 10 is configured to be portable to the user. Since the controller 18 is portable, the user can carry the entire medical device 10 and can carry out daily life without difficulty. The controller 18 does not have to be carried by the user, and may be installed in a cart or the like and the user pushes the cart.

Further, the generation pulse supply unit 40, the interference pulse supply unit 42, the control main body unit 44, and the battery 46 are not only housed in one housing 48 (see the dotted line in FIG. 1) but also installed at different locations. You may. For example, the generation pulse supply unit 40 and the control main body 44 may be in one housing, and the interference pulse supply unit 42 may be in another housing. Further, for example, the generation pulse supply unit 40, the interference pulse supply unit 42, and the control main body unit 44 may be housed in different housings. In this case, the battery 46 may be provided individually in each part. .. One housing and the other housing can be carried to different parts of the user, or one or both can be non-carrying.

The generation pulse supply unit 40 of the controller 18 supplies electric pulses (alternating current) of a predetermined voltage, current, and frequency to the pair of generation electrodes 20 via the electric wiring 19. Further, the generation pulse supply unit 40 makes it possible to change the frequency, pulse width, and stimulation time length of the electric pulse.

Specifically, the generation pulse supply unit 40 transmits an electric pulse having an electric pulse having a frequency higher than at least 50 Hz (for example, a medium frequency or a high frequency of 1 kHz to several tens of kHz) as a frequency for generating hydrogen peroxide as a pair of generation electrodes 20. Supply in between. This is because the electric pulse in this frequency range can transmit the electric pulse into the body with almost no muscle contraction.

The execution period of hydrogen peroxide generation by the generation pulse supply unit 40 is controlled by the control main unit 44. The pulse width (duty ratio), voltage value, and current value of the electric pulse may be set to appropriate values according to the purpose such as generation of hydrogen peroxide and delivery of hydrogen peroxide. The waveform of the electric pulse is not particularly limited, and may be a sine wave, a square wave, a triangular wave, or the like.

The interference pulse supply unit 42 of the controller 18 supplies electric pulses (alternating current) of a predetermined voltage, current, and frequency to the first pair electrode 32 and the second pair electrode 34 via the electric wiring 19. The interference pulse supply unit 42 also makes it possible to change the frequency, pulse width, and stimulation time of the electric pulse.

The frequency that becomes a bias in the electric pulse output by the interference pulse supply unit 42 may be appropriately set according to the depth of the muscle that causes the user's contraction. For example, if the muscle is deep from the body surface, a high frequency is set, and if the muscle is shallow from the body surface, a low frequency is set. Further, as described above, the interference pulse supply unit 42 has each frequency (first interference) so that the difference between the frequency supplied to the first pair electrode 32 and the frequency supplied to the second pair electrode 34 is 100 Hz or less. Frequency, second interference frequency) is set.

The output period of the interference low frequency by the interference pulse supply unit 42 is controlled by the control main body unit 44. The pulse width (duty ratio), voltage value, and current value of the electric pulse are appropriate according to the depth of the location where the interference low frequency occurs and the amount of hydrogen peroxide generated (output of the electric pulse of the generation frequency). Value should be set. Further, the waveform of the electric pulse output by the interference pulse supply unit 42 is not particularly limited, and may be a sine wave, a square wave, a triangular wave, or the like.

The control main body 44 of the controller 18 is configured as a computer having a processor, a memory, and an input / output interface (not shown). The control main body 44 is connected to each of the generation pulse supply unit 40 and the interference pulse supply unit 42 so that signals can be transmitted. By outputting an operation command to the generation pulse supply unit 40 and the interference pulse supply unit 42, the control main body unit 44 causes electrical stimulation by the pair of generation electrodes 20 and low interference by the plurality of pairs of interference electrodes 30. Controls the generation of frequencies.

Further, the control main body 44 may include an input / output device (for example, a touch panel) (not shown) that sets the operation of the medical device 10 by input from the user. The input / output device allows the user to arbitrarily set the duration of treatment (electrical stimulation), the strength of the electrical stimulation, and the like. Alternatively, the control main unit 44 may be configured to input physical information such as the height and weight of the user and the treatment site via an input / output device, and set the frequency for generating an electric pulse and the frequency for interference based on the physical information. Good.

Further, the control main body 44 obtains information on the operating state (for example, the output state of the electric pulse, the supply timing, etc.) from the generation pulse supply unit 40 and the interference pulse supply unit 42, so that the treatment status can be constantly controlled. It is preferable that the configuration is to monitor. Further, the controller 18 may be configured to measure the resistance (impedance) of the user by using a pair of electrodes 12 before generating hydrogen peroxide. This is because if the resistance is low, it can be said that the pair of electrodes 12 are in sufficient contact with the body surface of the user.

The medical device 10 according to the present embodiment is basically configured as described above, and a treatment method using the medical device 10 will be described.

When the purpose is to reduce visceral fat, the lower abdomen is covered with a pad 16 and the wearing body 14 is attached to the user. As shown in FIG. 2A, the pad 16 is attached with the attachment surface portion 16a having the plurality of electrodes 12 facing the body surface side. At the time of this attachment, it is preferable that the cathodes 22 of the pair of generation electrodes 20 are arranged to face each other at the treatment site.

Further, the controller 18 connected to the mounting body 14 is also carried on the body surface by a band or the like (not shown), and when the power supply (not shown) is turned on by the user, the generation pulse supply unit 40 and the interference pulse are turned on. The supply unit 42 and the control main unit 44 are activated. After that, treatment with the medical device 10 is performed, for example, according to the first processing flow shown in FIG. 3A.

Specifically, the medical device 10 carries out a hydrogen peroxide generation step of generating hydrogen peroxide in the body by the output of an electric pulse of a generation frequency with the start of treatment (step S10). That is, the control main body unit 44 issues an operation command to the generation pulse supply unit 40, and supplies an electric pulse having a predetermined generation frequency to the pair of generation electrodes 20. As a result, as shown in FIG. 4A, the electrons of the generation frequency emitted from the cathode 22 into the body move to the anode 24, and at this time, a chemical reaction occurs in the body due to some electrons, so that the electrons are located near the cathode 22. Hydrogen peroxide is produced as a secondary product. Therefore, as shown in FIG. 2B, the concentration of hydrogen peroxide increases in the vicinity of the subcutaneous portion of the position where the cathode 22 is arranged.

The control main body unit 44 measures the time when the electric pulse is supplied by the generation pulse supply unit 40, and supplies the electric pulse only for a preset time. This set time may be configured to be changeable according to information such as the output state of the electric pulse, the body shape of the user, and the treatment location.

The control main body 44 stops the supply of the electric pulse of the generation pulse supply unit 40 after executing the hydrogen peroxide generation step for a set time. Then, a standby step of waiting for a preset time is performed (step S11). The hydrogen peroxide produced in the vicinity of the position where the cathode 22 is arranged by the standby step can accelerate the treatment of this portion. It is not necessary to carry out the standby process.

After that, the control main body 44 carries out a hydrogen peroxide delivery step of flowing (diffusing) hydrogen peroxide into the body (step S12). At this time, the control main body 44 issues an operation command to the interference pulse supply unit 42, supplies the electric pulse of the first interference frequency to the first pair electrode 32, and supplies the electric pulse of the second interference frequency to the second pair electrode 32. It is supplied to the counter electrode 34.

For example, the interference pulse supply unit 42 supplies an electric pulse of 5000 Hz as the first interference frequency to the first pair electrode 32, and supplies an electric pulse of 5010 Hz as the second interference frequency to the second pair electrode 34. As a result, as shown in FIG. 4B, an interference low frequency is generated at a position where the line segment L1 of the first pair electrode 32 and the line segment L2 of the second pair electrode 34 intersect.

As described above, this interference low frequency can apply a low frequency to muscles located at a certain depth from the user's body surface. The interference pulse supply unit 42 has a configuration in which an electric pulse of the first interference frequency and an electric pulse of the second interference frequency are simultaneously and intermittently supplied (as an electric pulse group in which a plurality of electric pulses are grouped). You may. As a result, the supply and stop of the electric pulse of the interference frequency is repeated, so that the interference low frequency causes the muscle to contract and relax repeatedly. Therefore, the hydrogen peroxide generated in the body smoothly flows to the peripheral part of the muscle by the pumping action accompanying the contraction and relaxation of the muscle, and is easily diffused to the peripheral part of the arrangement position of the cathode 22. In the hydrogen peroxide delivery step, the frequency that becomes the bias of the electric pulse output by the interference pulse supply unit 42 may be changed. For example, the first interference frequency at the start of the hydrogen peroxide delivery process is 4000 Hz, the second interference frequency is 4010 Hz, the first interference frequency is 5000 Hz, and the second interference frequency is 5010 Hz over time. By increasing the bias frequency, it is also possible to achieve a pumping action based on smooth muscle contraction from superficial muscles to deep muscles. Further, a combination of a plurality of first and second interference frequencies suitable for the treatment site, for example, for the arm, abdomen, and thigh, is stored in advance in the memory of the control main body 44, and the user. May select an appropriate combination of first and second interference frequencies by selecting a treatment site from an input / output device (not shown).

After the hydrogen peroxide delivery step is carried out, the control main body 44 carries out a break step (step S13). At this time, the control body unit 44 stops the supply of electric pulses by the interference pulse supply unit 42. As a result, it is possible to rest the biological tissue of the portion that has been burdened with the production of hydrogen peroxide and the movement of hydrogen peroxide.

After the break step, if the power of the controller 18 is not turned off by the user, the process returns to step S10 and the same process is repeated. The control main unit 44 sets the number of executions of the first processing flow in advance, and after the processing up to step S13 is completed, confirms and counts the number of executions, and sets the number of executions to the set number. The power may be automatically turned off when the power is reached.

Further, the medical device 10 may be treated according to, for example, the second processing flow shown in FIG. 3B. That is, in the second processing flow, the control main body 44 simultaneously carries out the hydrogen peroxide generation step and the hydrogen peroxide delivery step (step S20).

Specifically, the control main body unit 44 issues an operation command to the generation pulse supply unit 40 and the interference pulse supply unit 42. Then, the generation pulse supply unit 40 generates hydrogen peroxide in the vicinity of the cathode 22 by supplying an electric pulse having a generation frequency to the pair of generation electrodes 20. On the other hand, the interference pulse supply unit 42 supplies electric pulses of interference frequencies (first and second interference frequencies) to each of the first pair electrode 32 and the second pair electrode 34, and determines from the body surface. Induces contraction and relaxation effects on deep muscles.

Therefore, the medical device 10 can generate hydrogen peroxide in the vicinity of the cathode 22 and allow the hydrogen peroxide generated by the contraction and relaxation of the muscle to flow around the arrangement position of the cathode 22. Then, after the hydrogen peroxide generation step and the hydrogen peroxide delivery step are simultaneously carried out for a predetermined time, the control main body 44 carries out a break step in the same manner as in the first processing flow (step S21). As a result, the living tissue can be rested.

Further, even after the break step, the control main body 44 determines the continuation of the treatment (repetition of the treatment) or the discontinuation of the treatment, and repeats the treatments of steps S20 and S21 when the treatment is continued, as in the first treatment flow. It is good.

As described above, the medical device 10 according to the present embodiment has a pair of generation electrodes 20 and a plurality of pairs of interference electrodes 30 to generate hydrogen peroxide in a living body and flow hydrogen peroxide. Can be managed well. That is, the pair of generation electrodes 20 generate hydrogen peroxide near the arrangement position of the cathode 22 by supplying an electric pulse, and increase the concentration of hydrogen peroxide at that position. On the other hand, the plurality of pairs of interference electrodes 30 generate an interference low frequency at a position overlapping the cathode 22 by supplying an electric pulse, thereby satisfactorily contracting the muscle (living tissue) at this position and delivering hydrogen peroxide. Can be prompted. That is, it is possible to increase the concentration of hydrogen peroxide in the treated area as compared with the infusion therapy, and the treatment with hydrogen peroxide can be promoted in a short time. Moreover, the plurality of electrodes 12 are non-invasively arranged on the body surface and do not require a doctor's procedure. In addition, the medical device 10 can reduce the occurrence of tissue inflammation and damage due to the large amount of hydrogen peroxide staying near the position where the cathode 22 is arranged, and after the hydrogen peroxide is transferred, it is peroxidized again. It becomes possible to generate hydrogen. Therefore, the production efficiency of hydrogen peroxide can be increased.

In this case, the medical device 10 has a body in which the frequency of the electric pulse supplied to the plurality of pairs of interference electrodes 30 is 1000 Hz or more and the frequency difference between the first pair electrode 32 and the second pair electrode 34 is 100 Hz or less. It contracts the muscles deep to some extent from the table. This makes it possible for hydrogen peroxide to penetrate and diffuse deep into the body.

Then, the medical device 10 can easily switch between the generation and flow of hydrogen peroxide by using the pair of generation electrodes 20 and the plurality of pairs of interference electrodes 30 as different electrodes, or the generation and flow of hydrogen peroxide. Various controls can be satisfactorily performed, such as simultaneously performing.

In addition, the medical device 10 promotes treatment at this position by generating hydrogen peroxide in the vicinity of the cathode 22 of the pair of generation electrodes 20. After that, by supplying an electric pulse to a plurality of pairs of interference electrodes 30, the muscle at the position where the cathode 22 is arranged can be contracted, and the generated hydrogen peroxide can be smoothly delivered.

Alternatively, the medical device 10 can immediately flow the generated hydrogen peroxide to the peripheral portion of the cathode 22 by contracting the muscle at the position where the cathode 22 is arranged while generating hydrogen peroxide. Therefore, it is possible to satisfactorily promote the treatment of the peripheral portion of the cathode 22.

Further, in the medical device 10, the cathode 22 of the pair of generation electrodes 20 and the plurality of pairs of interference electrodes 30 are arranged at an appropriate distance by the pad 16. As a result, the cathode 22 and a plurality of pairs of interference electrodes 30 can be easily arranged on the body surface when the pad 16 is attached, and the interference low frequency can be surely generated in the vicinity of the cathode 22.

The present invention is not limited to the above-described embodiment, and various modifications can be made according to the gist of the invention. For example, in the above-described embodiment, the pad 16 is provided with six electrodes 12 (cathode 22, anode 24, first positive electrode 32a, first negative electrode 32b, second positive electrode 34a, second negative electrode 34b). However, it goes without saying that various configurations can be applied to the medical device 10.

For example, as in the first modification shown in FIG. 5A, the mounting body 14A of the medical device 10A has the cathode 22 of the pair of generation electrodes 20 at the center position of the substantially square pad 16A, and the pair of generation electrodes 20A is used for generation. The anode 24 of the electrode 20 is provided at the lower right position of the pad 16A. The anode 24 is configured to also function as a plurality of pairs of interference electrodes 30.

That is, the first counter electrode 32 is composed of a first positive electrode 32a at the upper left position and a first negative electrode 32b at the lower right position, and the first negative electrode 32b and the anode 24 are the same electrode 12. The second counter electrode 34 is composed of a second positive electrode 34a at the upper right position and a second negative electrode 34b at the lower left position. As a result, when hydrogen peroxide is generated, the lower right electrode 12 is supplied with an electric pulse having a generation frequency from the controller 18 (generation pulse supply unit 40). On the other hand, when moving hydrogen peroxide, an electric pulse having an interference frequency for the first counter electrode 32 is supplied from the controller 18 (interference pulse supply unit 42).

Therefore, the same effect as that of the above-described embodiment can be obtained with the medical device 10A according to the first modification. In particular, in this medical device 10A, the number of electrodes 12 can be reduced because the anode 24 of the pair of generation electrodes 20 also serves as one electrode 12 of the plurality of pairs of interference electrodes 30, and the manufacturing cost Can be reduced.

Further, the wearing body 14B of the medical device 10B according to the second modification shown in FIG. 5B includes the first wearing body 50 and the second wearing body 52. Then, the pad 16B of the first mounting body 50 has a cathode 22 of a pair of generating electrodes 20 and a plurality of pairs of interference electrodes 30, and the second mounting body 52 has an anode 24 of a pair of generating electrodes 20. As described above, even if the anode 24 is provided on a member different from the cathode 22, the same effect as that of the above-described embodiment can be obtained by attaching the anode 24 to an appropriate place on the body surface of the user.

Further, the medical device 10B includes a third pair electrode 54 in addition to the first pair electrode 32 and the second pair electrode 34 as the plurality of interference electrodes 30. The controller 18 of the medical device 10B can adjust the muscle contraction in more detail and surely by supplying an electric pulse having an appropriate interference frequency to the three pairs of electrodes. That is, the medical devices 10, 10A, and 10B are not particularly limited in the number of a plurality of pairs of interference electrodes 30.

Claims (7)

Multiple electrodes placed on the body surface of the living body,
An electric pulse supply unit that supplies electric pulses to the plurality of electrodes is provided.
The plurality of electrodes constitute a pair of generation electrodes that generate hydrogen peroxide in the body at the position where the cathode is arranged by supplying the electric pulse.
Further, it is characterized in that a plurality of pairs of interference electrodes, which are arranged around the cathode and generate interference low frequencies at positions overlapping the cathode in a plan view, can be configured by supplying the electric pulses having different frequencies. Medical equipment. In the medical device according to claim 1.
The electric pulse supply unit has a frequency of 1000 Hz or more for each of the electric pulses supplied to the plurality of pairs of interference electrodes, and of the first pair electrode and the second pair electrode of the plurality of pairs of interference electrodes. A medical device characterized in that the difference in frequency of the electric pulses is 100 Hz or less. In the medical device according to claim 1 or 2.
A medical device characterized in that the pair of generation electrodes and the plurality of pairs of interference electrodes are mutually different electrodes. In the medical device according to claim 1 or 2.
A medical device characterized in that the anode of the pair of generation electrodes also serves as any one of the plurality of pairs of interference electrodes. In the medical device according to any one of claims 1 to 4.
The electric pulse supply unit supplies the electric pulse of the generation frequency for generating the hydrogen peroxide to the pair of generation electrodes to generate the hydrogen peroxide, and then produces the interference low frequency. A medical device characterized in that the electric pulse of the above is supplied to each of the plurality of pairs of interference electrodes. In the medical device according to any one of claims 1 to 3.
The electric pulse supply unit generates the interference low frequency while supplying the electric pulse of the generation frequency for generating the hydrogen peroxide to the pair of generation electrodes to generate the hydrogen peroxide. A medical device characterized in that the electric pulses of different frequencies are supplied to each of the plurality of pairs of interference electrodes. In the medical device according to any one of claims 1 to 6.
A medical device characterized by having one pad in which the cathodes of the pair of generation electrodes are arranged at the center positions of the electrodes of the plurality of pairs of interference electrodes.

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