JPWO2019173503A5 - - Google Patents

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Publication number
JPWO2019173503A5
JPWO2019173503A5 JP2020570410A JP2020570410A JPWO2019173503A5 JP WO2019173503 A5 JPWO2019173503 A5 JP WO2019173503A5 JP 2020570410 A JP2020570410 A JP 2020570410A JP 2020570410 A JP2020570410 A JP 2020570410A JP WO2019173503 A5 JPWO2019173503 A5 JP WO2019173503A5
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JP
Japan
Prior art keywords
seq
sequence
spik
antibody
chain variable
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Application number
JP2020570410A
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English (en)
Japanese (ja)
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JP2021515597A (ja
JP7328261B2 (ja
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Priority claimed from PCT/US2019/020999 external-priority patent/WO2019173503A2/en
Publication of JP2021515597A publication Critical patent/JP2021515597A/ja
Publication of JPWO2019173503A5 publication Critical patent/JPWO2019173503A5/ja
Priority to JP2023127022A priority Critical patent/JP7539536B2/ja
Application granted granted Critical
Publication of JP7328261B2 publication Critical patent/JP7328261B2/ja
Active legal-status Critical Current
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JP2020570410A 2018-03-06 2019-03-06 セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法 Active JP7328261B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023127022A JP7539536B2 (ja) 2018-03-06 2023-08-03 セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862639345P 2018-03-06 2018-03-06
US62/639,345 2018-03-06
US201862639850P 2018-03-07 2018-03-07
US62/639,850 2018-03-07
PCT/US2019/020999 WO2019173503A2 (en) 2018-03-06 2019-03-06 Serine protease inhibitor kazal (spik) compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023127022A Division JP7539536B2 (ja) 2018-03-06 2023-08-03 セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法

Publications (3)

Publication Number Publication Date
JP2021515597A JP2021515597A (ja) 2021-06-24
JPWO2019173503A5 true JPWO2019173503A5 (es) 2022-03-15
JP7328261B2 JP7328261B2 (ja) 2023-08-16

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ID=65818672

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020570410A Active JP7328261B2 (ja) 2018-03-06 2019-03-06 セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法
JP2023127022A Active JP7539536B2 (ja) 2018-03-06 2023-08-03 セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023127022A Active JP7539536B2 (ja) 2018-03-06 2023-08-03 セリンプロテアーゼ阻害剤カザル（ｓｐｉｋ）組成物および方法

Country Status (6)

Country Link
US (1) US20210253734A1 (es)
EP (1) EP3762426A2 (es)
JP (2) JP7328261B2 (es)
CN (1) CN112292401A (es)
CA (1) CA3093295A1 (es)
WO (1) WO2019173503A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021007338A1 (en) * 2019-07-08 2021-01-14 Imcare Biotech, Llc. Anti-serine protease inhibitor kazal (spik) antibodies, immunoconjugates, and methods of use
US20240043512A1 (en) 2019-09-11 2024-02-08 Imcare Biotech, Llc Epitopes of anti-serine protease inhibitor kazal (spik) antibodies
EP4211468A4 (en) * 2020-09-11 2024-10-09 Glympse Bio Inc DETECTION OF EX VIVO PROTEASE ACTIVITY FOR DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT OF DISEASES

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
WO1992022653A1 (en) 1991-06-14 1992-12-23 Genentech, Inc. Method for making humanized antibodies
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
WO2007030560A2 (en) * 2005-09-08 2007-03-15 Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine Identification of modulators of serine protease inhibitor kazal and their use as anti-cancer and anti-viral agents
WO2011102999A2 (en) * 2010-02-19 2011-08-25 The Regents Of The University Of Michigan Spink1 targeted therapy
WO2012078752A2 (en) 2010-12-09 2012-06-14 Philadelphia Health & Education Corporation D/B/A Serine protease inhibitor kazal antibodies
CN103596985B (zh) * 2011-04-19 2016-06-08 美国政府(由卫生和人类服务部的部长所代表) 对磷脂酰肌醇蛋白聚糖3特异的人单克隆抗体及其用途
KR20200103706A (ko) * 2017-12-22 2020-09-02 조운스 테라퓨틱스, 인크. Lilrb2에 대한 항체
WO2021211753A1 (en) * 2020-04-15 2021-10-21 Voyager Therapeutics, Inc. Tau binding compounds

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