JPWO2018228932A5 - - Google Patents
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- Publication number
- JPWO2018228932A5 JPWO2018228932A5 JP2019568352A JP2019568352A JPWO2018228932A5 JP WO2018228932 A5 JPWO2018228932 A5 JP WO2018228932A5 JP 2019568352 A JP2019568352 A JP 2019568352A JP 2019568352 A JP2019568352 A JP 2019568352A JP WO2018228932 A5 JPWO2018228932 A5 JP WO2018228932A5
- Authority
- JP
- Japan
- Prior art keywords
- glucose
- insulin
- titration
- time frame
- scale
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 122
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 93
- 239000008103 glucose Substances 0.000 claims 93
- 102000004877 Insulin Human genes 0.000 claims 62
- 108090001061 Insulin Proteins 0.000 claims 62
- 229940125396 insulin Drugs 0.000 claims 61
- 238000005259 measurement Methods 0.000 claims 48
- 238000004448 titration Methods 0.000 claims 33
- 229940079593 drug Drugs 0.000 claims 32
- 239000003814 drug Substances 0.000 claims 32
- 238000000034 method Methods 0.000 claims 11
- 230000002459 sustained effect Effects 0.000 claims 11
- 238000011156 evaluation Methods 0.000 claims 10
- 230000002218 hypoglycaemic effect Effects 0.000 claims 8
- 230000000694 effects Effects 0.000 claims 7
- 208000013016 Hypoglycemia Diseases 0.000 claims 5
- 102000016261 Long-Acting Insulin Human genes 0.000 claims 4
- 108010092217 Long-Acting Insulin Proteins 0.000 claims 4
- 229940100066 Long-acting insulin Drugs 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 238000001802 infusion Methods 0.000 claims 3
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 230000004044 response Effects 0.000 claims 2
- 238000004590 computer program Methods 0.000 claims 1
- 239000004026 insulin derivative Substances 0.000 claims 1
- 229940127560 insulin pen Drugs 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044006A JP7389834B2 (ja) | 2017-06-15 | 2022-03-18 | 適合可能な標的グルコースレベルを用いる基礎タイトレーション |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762520139P | 2017-06-15 | 2017-06-15 | |
| US62/520,139 | 2017-06-15 | ||
| US201762522811P | 2017-06-21 | 2017-06-21 | |
| US62/522,811 | 2017-06-21 | ||
| EP17178877.1 | 2017-06-29 | ||
| EP17178877 | 2017-06-29 | ||
| EP17190146 | 2017-09-08 | ||
| EP17190146.5 | 2017-09-08 | ||
| PCT/EP2018/065126 WO2018228932A1 (en) | 2017-06-15 | 2018-06-08 | Basal titration with adaptive target glucose level |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044006A Division JP7389834B2 (ja) | 2017-06-15 | 2022-03-18 | 適合可能な標的グルコースレベルを用いる基礎タイトレーション |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020524844A JP2020524844A (ja) | 2020-08-20 |
| JPWO2018228932A5 true JPWO2018228932A5 (https=) | 2022-03-29 |
| JP2020524844A5 JP2020524844A5 (https=) | 2022-03-29 |
| JP7178370B2 JP7178370B2 (ja) | 2022-11-25 |
Family
ID=62492661
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019568352A Active JP7178370B2 (ja) | 2017-06-15 | 2018-06-08 | 適合可能な標的グルコースレベルを用いる基礎タイトレーション |
| JP2022044006A Active JP7389834B2 (ja) | 2017-06-15 | 2022-03-18 | 適合可能な標的グルコースレベルを用いる基礎タイトレーション |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044006A Active JP7389834B2 (ja) | 2017-06-15 | 2022-03-18 | 適合可能な標的グルコースレベルを用いる基礎タイトレーション |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11298461B2 (https=) |
| EP (2) | EP3758008A1 (https=) |
| JP (2) | JP7178370B2 (https=) |
| CN (2) | CN117912631A (https=) |
| MA (1) | MA49422A (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3826700A1 (en) * | 2018-07-26 | 2021-06-02 | Sanofi | Method of adjusting medication doses |
| AU2023260398A1 (en) | 2022-04-26 | 2024-11-21 | Dexcom, Inc. | System and method for titrating basal insulin doses |
| WO2024192362A1 (en) * | 2023-03-16 | 2024-09-19 | University Of Virginia | Method for mitigating hypoglycemia rebound in an automated insulin delivery system |
| JPWO2024214253A1 (https=) * | 2023-04-13 | 2024-10-17 | ||
| WO2025090855A1 (en) * | 2023-10-26 | 2025-05-01 | University Of Virginia Patent Foundation | Targeted basal insulin titration using sparse and dense glucose measurements |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL127370A (en) | 1998-12-02 | 2004-05-12 | Yaskawa Eshed Technology Ltd | Control system and method for servo mechanism |
| US6923763B1 (en) | 1999-08-23 | 2005-08-02 | University Of Virginia Patent Foundation | Method and apparatus for predicting the risk of hypoglycemia |
| US7404796B2 (en) | 2004-03-01 | 2008-07-29 | Becton Dickinson And Company | System for determining insulin dose using carbohydrate to insulin ratio and insulin sensitivity factor |
| US20050065760A1 (en) * | 2003-09-23 | 2005-03-24 | Robert Murtfeldt | Method for advising patients concerning doses of insulin |
| US20070092888A1 (en) | 2003-09-23 | 2007-04-26 | Cornelius Diamond | Diagnostic markers of hypertension and methods of use thereof |
| JP4273036B2 (ja) | 2004-05-12 | 2009-06-03 | 中 奥村 | 投薬支援プログラム、投薬支援装置、投薬支援プログラムを記録した記録媒体及び投薬支援システム |
| US7509156B2 (en) * | 2005-05-18 | 2009-03-24 | Clarian Health Partners, Inc. | System for managing glucose levels in patients with diabetes or hyperglycemia |
| DK1972270T3 (da) | 2007-03-23 | 2011-01-24 | Hoffmann La Roche | Fremgangsmåde og glucoseovervågningssystem til overvågning af individuelt metabolisk respons |
| EP2156684A4 (en) | 2007-05-14 | 2012-10-24 | Abbott Diabetes Care Inc | METHOD AND DEVICE FOR PROVIDING DATA PROCESSING AND CONTROL IN A MEDICAL COMMUNICATION SYSTEM |
| EP4159114B1 (en) * | 2007-10-09 | 2024-04-10 | DexCom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| EP2245568A4 (en) | 2008-02-20 | 2012-12-05 | Univ Mcmaster | EXPERIMENTAL SYSTEM FOR DETERMINING THE RESPONSE OF PATIENTS TO TREATMENT |
| PT2260423T (pt) | 2008-04-04 | 2018-05-30 | Hygieia Inc | Aparelho para optimizar o regime de dosagem de insulina a um paciente |
| US9220456B2 (en) * | 2008-04-04 | 2015-12-29 | Hygieia, Inc. | Systems, methods and devices for achieving glycemic balance |
| TWI394580B (zh) * | 2008-04-28 | 2013-05-01 | Halozyme Inc | 超快起作用胰島素組成物 |
| US20100256047A1 (en) * | 2009-04-03 | 2010-10-07 | Lifescan, Inc. | Analyte Measurement and Management Device and Associated Methods |
| US8175812B2 (en) | 2008-06-25 | 2012-05-08 | Roche Diagnostics Operations, Inc. | Method, system, and computer program product for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights |
| WO2010089307A1 (en) * | 2009-02-04 | 2010-08-12 | Sanofi-Aventis Deutschland Gmbh | Medical system and method for providing information for glycemic control |
| US8562587B2 (en) | 2009-02-25 | 2013-10-22 | University Of Virginia Patent Foundation | CGM-based prevention of hypoglycemia via hypoglycemia risk assessment and smooth reduction of insulin delivery |
| JP5654587B2 (ja) | 2009-06-30 | 2015-01-14 | ライフスキャン・インコーポレイテッドＬｉｆｅｓｃａｎ，Ｉｎｃ． | 基礎インスリン療法を算出する分析物試験方法及び装置 |
| WO2011084208A1 (en) | 2009-12-21 | 2011-07-14 | Stc.Unm | System and methods for estimating hba1c, treatment response, and hypoglycemia risk using self-monitoring of blood glucose data |
| US8532933B2 (en) | 2010-06-18 | 2013-09-10 | Roche Diagnostics Operations, Inc. | Insulin optimization systems and testing methods with adjusted exit criterion accounting for system noise associated with biomarkers |
| WO2012122520A1 (en) | 2011-03-10 | 2012-09-13 | Abbott Diabetes Care Inc. | Multi-function analyte monitor device and methods of use |
| RU2602040C2 (ru) | 2011-08-26 | 2016-11-10 | Университи Оф Вирджиния Патент Фоундэйшион | Способ, система и машиночитаемый носитель для адаптационного рекомендательного контроля сахарного диабета |
| TW201318602A (zh) * | 2011-11-14 | 2013-05-16 | Joinsoon Medical Technology Co Ltd | 具胰島素參數之血糖檢測統計方法及其血糖檢測機 |
| TW201333870A (zh) * | 2011-12-21 | 2013-08-16 | 艾登工具股份有限公司 | 決定病人胰島素療法的系統及方法 |
| US9227014B2 (en) | 2013-02-07 | 2016-01-05 | The Board Of Trustees Of The Laland Stanford Junior University | Kalman filter based on-off switch for insulin pump |
| EP2967344A4 (en) | 2013-03-15 | 2016-11-23 | Abbott Diabetes Care Inc | DEVICES, SYSTEMS AND METHODS RELATING TO ANALYTICAL MONITORING DEVICES AND DEVICES THEREWITH |
| EP4420603A3 (en) | 2013-03-15 | 2024-11-20 | Abbott Diabetes Care, Inc. | System and method to manage diabetes based on glucose median, glucose variability, and hypoglycemic risk |
| US20150006192A1 (en) | 2013-06-26 | 2015-01-01 | WellDoc, Inc. | Systems and methods for clinical decision-making |
| US9898585B2 (en) | 2014-01-31 | 2018-02-20 | Aseko, Inc. | Method and system for insulin management |
| WO2015128740A2 (en) | 2014-02-28 | 2015-09-03 | Eco-Fusion | Systems for predicting hypoglycemia and methods of use thereof |
| US10722650B2 (en) | 2014-03-28 | 2020-07-28 | Roche Diabetes Care, Inc. | System and method for adjusting therapy based on risk associated with a glucose state |
| GB201407896D0 (en) * | 2014-05-05 | 2014-06-18 | Joanneum Res Forschungsgmbh | Insulin dosage proposal system |
| US10617363B2 (en) | 2015-04-02 | 2020-04-14 | Roche Diabetes Care, Inc. | Methods and systems for analyzing glucose data measured from a person having diabetes |
| US10657224B2 (en) | 2015-09-25 | 2020-05-19 | Accenture Global Solutions Limited | Monitoring and treatment dosage prediction system |
| US12383166B2 (en) | 2016-05-23 | 2025-08-12 | Insulet Corporation | Insulin delivery system and methods with risk-based set points |
| US10304315B2 (en) | 2016-06-09 | 2019-05-28 | Amp Llc | Systems and methods for health monitoring and providing emergency support |
| US20190287645A1 (en) | 2016-07-06 | 2019-09-19 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| US10971030B2 (en) | 2017-01-26 | 2021-04-06 | International Business Machines Corporation | Remote physical training |
-
2018
- 2018-06-08 CN CN202311662916.9A patent/CN117912631A/zh active Pending
- 2018-06-08 US US16/622,326 patent/US11298461B2/en active Active
- 2018-06-08 JP JP2019568352A patent/JP7178370B2/ja active Active
- 2018-06-08 EP EP20183645.9A patent/EP3758008A1/en active Pending
- 2018-06-08 EP EP18728654.7A patent/EP3639268B1/en active Active
- 2018-06-08 MA MA049422A patent/MA49422A/fr unknown
- 2018-06-08 CN CN201880039764.8A patent/CN110741438B/zh active Active
-
2022
- 2022-03-04 US US17/687,201 patent/US12109392B2/en active Active
- 2022-03-18 JP JP2022044006A patent/JP7389834B2/ja active Active
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