JPWO2018185040A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2018185040A5 JPWO2018185040A5 JP2019554673A JP2019554673A JPWO2018185040A5 JP WO2018185040 A5 JPWO2018185040 A5 JP WO2018185040A5 JP 2019554673 A JP2019554673 A JP 2019554673A JP 2019554673 A JP2019554673 A JP 2019554673A JP WO2018185040 A5 JPWO2018185040 A5 JP WO2018185040A5
- Authority
- JP
- Japan
- Prior art keywords
- ffr
- value
- coronary
- stenosis
- location
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004351 coronary vessel Anatomy 0.000 claims description 88
- 238000005259 measurement Methods 0.000 claims description 31
- 208000031481 Pathologic Constriction Diseases 0.000 claims description 29
- 238000004088 simulation Methods 0.000 claims description 29
- 208000037804 stenosis Diseases 0.000 claims description 29
- 230000036262 stenosis Effects 0.000 claims description 29
- 230000000747 cardiac effect Effects 0.000 claims description 15
- 238000002591 computed tomography Methods 0.000 claims description 9
- 230000017531 blood circulation Effects 0.000 claims description 6
- 238000004364 calculation method Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 description 14
- 238000003384 imaging method Methods 0.000 description 9
- 238000013459 approach Methods 0.000 description 8
- 230000011218 segmentation Effects 0.000 description 8
- 230000005855 radiation Effects 0.000 description 6
- 238000009530 blood pressure measurement Methods 0.000 description 5
- 230000036772 blood pressure Effects 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 101000666730 Homo sapiens T-complex protein 1 subunit alpha Proteins 0.000 description 3
- 102100038410 T-complex protein 1 subunit alpha Human genes 0.000 description 3
- 208000029078 coronary artery disease Diseases 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 201000000057 Coronary Stenosis Diseases 0.000 description 2
- 206010011089 Coronary artery stenosis Diseases 0.000 description 2
- 238000004422 calculation algorithm Methods 0.000 description 2
- 238000010968 computed tomography angiography Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 206010057469 Vascular stenosis Diseases 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 210000005242 cardiac chamber Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 238000002586 coronary angiography Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000003708 edge detection Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000000544 hyperemic effect Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000010801 machine learning Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 210000002321 radial artery Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762482236P | 2017-04-06 | 2017-04-06 | |
| US62/482,236 | 2017-04-06 | ||
| US201762557195P | 2017-09-12 | 2017-09-12 | |
| US62/557,195 | 2017-09-12 | ||
| PCT/EP2018/058376 WO2018185040A1 (en) | 2017-04-06 | 2018-04-02 | Standardized coronary artery disease metric |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020512871A JP2020512871A (ja) | 2020-04-30 |
| JP2020512871A5 JP2020512871A5 (https=) | 2022-09-21 |
| JPWO2018185040A5 true JPWO2018185040A5 (https=) | 2022-09-21 |
| JP7300392B2 JP7300392B2 (ja) | 2023-06-29 |
Family
ID=62025784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019554673A Active JP7300392B2 (ja) | 2017-04-06 | 2018-04-02 | 標準化された冠動脈疾患メトリック |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11576637B2 (https=) |
| EP (1) | EP3606433B1 (https=) |
| JP (1) | JP7300392B2 (https=) |
| CN (1) | CN110612063B (https=) |
| WO (1) | WO2018185040A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10210956B2 (en) | 2012-10-24 | 2019-02-19 | Cathworks Ltd. | Diagnostically useful results in real time |
| US9390232B2 (en) * | 2014-03-24 | 2016-07-12 | Heartflow, Inc. | Systems and methods for modeling changes in patient-specific blood vessel geometry and boundary conditions |
| EP4300419A3 (en) | 2016-05-16 | 2024-04-03 | Cathworks Ltd. | System for vascular assessment |
| EP3461253B1 (en) | 2016-05-16 | 2023-08-09 | Cathworks Ltd. | Selection of vascular paths from images |
| EP4663131A3 (en) | 2019-04-01 | 2026-01-28 | Cathworks Ltd. | Methods and apparatus for angiographic image selection |
| EP4033964B1 (en) | 2019-09-23 | 2025-04-09 | Cathworks Ltd. | Methods, apparatus, and system for synchronization between a three-dimensional vascular model and an imaging device |
| CN113648059B (zh) * | 2021-08-26 | 2023-09-29 | 上海联影医疗科技股份有限公司 | 手术规划评估方法、计算机设备和存储介质 |
| US12315076B1 (en) | 2021-09-22 | 2025-05-27 | Cathworks Ltd. | Four-dimensional motion analysis of a patient's coronary arteries and myocardial wall |
| IL314862A (en) | 2022-02-10 | 2024-10-01 | Cathworks Ltd | System and method for machine-learning based sensor analysis and vascular tree segmentation |
| KR102695790B1 (ko) * | 2022-03-03 | 2024-08-20 | 연세대학교 산학협력단 | 하이브리드 방식을 통한 관상동맥 ct 이미지에서의 관상동맥 및 상행 대동맥 자동 추출 시스템 및 그 방법 |
| IL326434A (en) | 2023-08-09 | 2026-04-01 | Cathworks Ltd | User interface and signal leakage testing for vascular index measurement |
| IL326432A (en) | 2023-08-09 | 2026-04-01 | Cathworks Ltd | Coronary artery assessment after PCI |
| US12499646B1 (en) | 2024-06-12 | 2025-12-16 | Cathworks Ltd. | Three-dimensional sizing tool for cardiac assessment |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8315812B2 (en) * | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| US10373700B2 (en) * | 2012-03-13 | 2019-08-06 | Siemens Healthcare Gmbh | Non-invasive functional assessment of coronary artery stenosis including simulation of hyperemia by changing resting microvascular resistance |
| JP6173438B2 (ja) | 2012-05-14 | 2017-08-02 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 血管の狭窄のための冠血流予備量比（ｆｆｒ）値の決定 |
| US10433740B2 (en) * | 2012-09-12 | 2019-10-08 | Heartflow, Inc. | Systems and methods for estimating ischemia and blood flow characteristics from vessel geometry and physiology |
| CN104768465B (zh) | 2012-11-06 | 2018-06-19 | 皇家飞利浦有限公司 | 血流储备分数(ffr)指标 |
| JP6305742B2 (ja) | 2012-11-30 | 2018-04-04 | キヤノンメディカルシステムズ株式会社 | 医用画像診断装置、表示方法 |
| JP6334902B2 (ja) * | 2012-11-30 | 2018-05-30 | キヤノンメディカルシステムズ株式会社 | 医用画像処理装置 |
| WO2015017571A1 (en) | 2013-07-30 | 2015-02-05 | Heartflow, Inc. | Method and system for modeling blood flow with boundary conditions for optimized diagnostic performance |
| US9842401B2 (en) | 2013-08-21 | 2017-12-12 | Koninklijke Philips N.V. | Segmentation apparatus for interactively segmenting blood vessels in angiographic image data |
| CN105517492B (zh) * | 2013-09-06 | 2019-10-18 | 皇家飞利浦有限公司 | 用于处理心脏数据的处理设备 |
| CN104518216B (zh) * | 2013-09-26 | 2017-09-01 | 清华大学 | 磷酸铁锂的制备方法 |
| JP6396468B2 (ja) * | 2013-12-04 | 2018-09-26 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 機能性狭窄解析を向上させる局所ｆｆｒ推定及び視覚化 |
| CN106163388B (zh) | 2014-03-31 | 2020-02-14 | 皇家飞利浦有限公司 | 用于处理生命体的心脏数据的处理装置和方法 |
| WO2016001017A1 (en) | 2014-06-30 | 2016-01-07 | Koninklijke Philips N.V. | Apparatus for determining a fractional flow reserve value |
| US9195801B1 (en) | 2014-08-05 | 2015-11-24 | Heartflow, Inc. | Systems and methods for treatment planning based on plaque progression and regression curves |
| US9349178B1 (en) * | 2014-11-24 | 2016-05-24 | Siemens Aktiengesellschaft | Synthetic data-driven hemodynamic determination in medical imaging |
| WO2016087396A1 (en) | 2014-12-02 | 2016-06-09 | Koninklijke Philips N.V. | Fractional flow reserve determination |
| EP3229688B1 (en) * | 2014-12-08 | 2020-10-28 | Koninklijke Philips N.V. | Device and method to recommend diagnostic procedure based on co-registered angiographic image and physiological information measured by intravascular device |
| US10872698B2 (en) | 2015-07-27 | 2020-12-22 | Siemens Healthcare Gmbh | Method and system for enhancing medical image-based blood flow computations using physiological measurements |
| CN105078425B (zh) * | 2015-09-09 | 2016-06-08 | 苏州润心医疗科技有限公司 | 冠状动脉负荷检测系统及检测方法 |
| CN109789218A (zh) | 2016-06-23 | 2019-05-21 | 菲吉乐科(加拿大)有限公司 | 噬菌体的微囊化和相关产品 |
-
2018
- 2018-04-02 WO PCT/EP2018/058376 patent/WO2018185040A1/en not_active Ceased
- 2018-04-02 US US16/500,215 patent/US11576637B2/en active Active
- 2018-04-02 EP EP18718721.6A patent/EP3606433B1/en active Active
- 2018-04-02 JP JP2019554673A patent/JP7300392B2/ja active Active
- 2018-04-02 CN CN201880030136.3A patent/CN110612063B/zh active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7300392B2 (ja) | 標準化された冠動脈疾患メトリック | |
| JP7313284B2 (ja) | 冠血流予備量比シミュレーションパラメータのカスタマイズ、キャリブレーション、及び／又はトレーニング | |
| US11055845B2 (en) | Vascular tree standardization for biophysical simulation and/or an extension simulation for pruned portions | |
| EP3140757B1 (en) | Method and system for non-invasive functional assessment of coronary artery stenosis using flow computations in models based on diseased patients and hypothetical normal anatomical models | |
| US11839457B2 (en) | Measurement guidance for coronary flow estimation from Bernoulli's Principle | |
| CN113164131B (zh) | 针对血液动力学模拟的最相关的x射线图像选择 | |
| JP6484760B2 (ja) | 非侵襲的血流予備量比（ｆｆｒ）に対する側副血流モデル化 | |
| JP7426824B2 (ja) | 非侵襲的イメージングベースのｆｆｒのインタラクションモニタリング | |
| JP6632989B2 (ja) | 動脈網における流量および圧力勾配を患者特定コンピュータ断層撮影アルゴリズムに基づくコントラスト分布から判断するための方法 | |
| JP2019034160A (ja) | 患者固有の幾何学的形状モデルを変更することによって治療を決定する方法及びシステム | |
| JP6749917B2 (ja) | ｉＦＲ−ＣＴ | |
| US20190076196A1 (en) | Vessel geometry and additional boundary conditions for hemodynamic ffr/ifr simulations from intravascular imaging | |
| JPWO2018185040A5 (https=) | ||
| JP7232245B2 (ja) | モデル及びイメージングデータに基づく冠動脈健康状態予測 |