JPWO2018009624A5 - - Google Patents

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Publication number
JPWO2018009624A5
JPWO2018009624A5 JP2019500446A JP2019500446A JPWO2018009624A5 JP WO2018009624 A5 JPWO2018009624 A5 JP WO2018009624A5 JP 2019500446 A JP2019500446 A JP 2019500446A JP 2019500446 A JP2019500446 A JP 2019500446A JP WO2018009624 A5 JPWO2018009624 A5 JP WO2018009624A5
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JP
Japan
Prior art keywords
seq
amino acids
heteromultimer
heteromultimers
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2019500446A
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English (en)
Japanese (ja)
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JP2019527547A (ja
JP7159148B2 (ja
JP2019527547A5 (pl
Publication date
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Priority claimed from PCT/US2017/040849 external-priority patent/WO2018009624A1/en
Publication of JP2019527547A publication Critical patent/JP2019527547A/ja
Publication of JP2019527547A5 publication Critical patent/JP2019527547A5/ja
Priority to JP2022144508A priority Critical patent/JP2022172479A/ja
Publication of JPWO2018009624A5 publication Critical patent/JPWO2018009624A5/ja
Application granted granted Critical
Publication of JP7159148B2 publication Critical patent/JP7159148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019500446A 2016-07-07 2017-07-06 Tgfベータスーパーファミリーホモ多量体およびその使用 Active JP7159148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022144508A JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662359614P 2016-07-07 2016-07-07
US62/359,614 2016-07-07
US201662404670P 2016-10-05 2016-10-05
US62/404,670 2016-10-05
PCT/US2017/040849 WO2018009624A1 (en) 2016-07-07 2017-07-06 Tgf-beta superfamily heteromultimers and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022144508A Division JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Publications (4)

Publication Number Publication Date
JP2019527547A JP2019527547A (ja) 2019-10-03
JP2019527547A5 JP2019527547A5 (pl) 2020-08-13
JPWO2018009624A5 true JPWO2018009624A5 (pl) 2022-09-22
JP7159148B2 JP7159148B2 (ja) 2022-10-24

Family

ID=60913181

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019500446A Active JP7159148B2 (ja) 2016-07-07 2017-07-06 Tgfベータスーパーファミリーホモ多量体およびその使用
JP2022144508A Pending JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022144508A Pending JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Country Status (6)

Country Link
US (1) US20200071382A1 (pl)
EP (1) EP3481860A4 (pl)
JP (2) JP7159148B2 (pl)
AU (2) AU2017293778B2 (pl)
CA (1) CA3029890A1 (pl)
WO (1) WO2018009624A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6810702B2 (ja) 2015-04-06 2021-01-06 アクセルロン ファーマ インコーポレイテッド シングルアームi型およびii型受容体融合タンパク質およびその使用
WO2016164503A1 (en) 2015-04-06 2016-10-13 Acceleron Pharma Inc. Alk7:actriib heteromultimers and uses thereof
MA41919A (fr) 2015-04-06 2018-02-13 Acceleron Pharma Inc Hétéromultimères alk4:actriib et leurs utilisations
CN110036025B (zh) 2016-10-05 2024-03-22 阿塞勒隆制药公司 变体ActRIIB蛋白及其用途
KR20190075078A (ko) 2016-10-05 2019-06-28 악셀레론 파마 인코포레이티드 ALK4:ActRIIB 이형다량체 및 이의 용도
WO2019213442A1 (en) * 2018-05-03 2019-11-07 Acceleron Pharma Inc. MULTISPECIFIC BINDERS OF TGFβ-SUPERFAMILY LIGANDS AND USES THEREOF
AU2019285299A1 (en) * 2018-06-15 2020-12-03 Acceleron Pharma Inc. Bi-and tri-functional fusion proteins and uses thereof
WO2023091968A1 (en) 2021-11-17 2023-05-25 Disc Medicine, Inc. Methods for treating anemia of kidney disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2827188C (en) * 2011-03-17 2020-02-11 Itai Benhar Bi- and monospecific, asymmetric antibodies and methods of generating the same
CN108178789B (zh) * 2011-04-20 2021-11-02 阿塞勒隆制药公司 内皮糖蛋白多肽及其用途
US20140193425A1 (en) * 2012-10-05 2014-07-10 Acceleron Pharma, Inc. Treatment of cancer with alk1 antagonists
EP3851118A1 (en) * 2013-10-25 2021-07-21 Acceleron Pharma Inc. Endoglin peptides to treat fibrotic diseases
WO2015147908A1 (en) * 2014-03-28 2015-10-01 Acceleron Pharma, Inc. Use of activin receptor-like kinase 1 (alk-1) antagonists in the treatment of cancer
WO2015160940A1 (en) * 2014-04-15 2015-10-22 President And Fellows Of Harvard College Bi-specific agents

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