JPWO2015033667A1 - Guide wire - Google Patents

Abstract

An object of the present invention is to provide a guide wire having a light-transmitting property and a tip flexibility that enables smooth movement in a living body lumen. The guide wire (10) intersects the axial direction of the wire main body (11) at least at a part of the elongated wire main body (11) and the distal end side in the axial direction of the wire main body (11). A light transmitting portion (20) having a light transmitting property capable of transmitting light irradiated in a direction, and the light transmitting portion (20) has a cross-sectional area in a direction perpendicular to the axis from the proximal end side to the distal end side. There is a lumen (21) that has changed to become larger.

Description

  The present invention relates to a guide wire used in the medical field.

  2. Description of the Related Art A catheter device that is inserted into a living body lumen such as a blood vessel and used to acquire various diagnostic images for diagnosing the inside of the lumen is known.

  As this type of catheter device, for example, an ultrasonic wave that oscillates from inside the lumen, receives the ultrasonic wave reflected by the inner wall of the lumen at a predetermined detection unit, and generates a tomographic image based on the reception result There are image diagnostic apparatuses, optical image diagnostic apparatuses that irradiate optical signals instead of ultrasonic waves, receive reflected light reflected on the inner wall of the lumen, and generate tomographic images based on the light reception results. . When each of the above catheter devices is used, by using a guide wire generally used in the medical field, a predetermined portion of each catheter device (for example, a target portion of a biological lumen to be diagnosed) (for example, , Oscillation unit, light emitting unit, detection unit, etc.) can be smoothly reached.

  However, since a conventional guide wire is configured to have a metal core, when used in a catheter device that acquires an image by an optical technique, light is blocked by the guide wire and is displayed on the image. The so-called “back shadow” is generated by the guide wire. Since the blood vessel wall in the portion where the back shadow occurs is not displayed on the image, it is difficult to visually diagnose the blood vessel wall in the portion where the back shadow occurs.

  In view of the above points, a part of the guide wire is made of a resin material or glass material having light transmittance, and the occurrence of back shadow is prevented by transmitting light through the portion. A guide wire that enables the above has been proposed (see Patent Document 1).

International Publication No. 2011/114600

  A guide wire used in the medical field is provided with a tip flexibility for allowing the guide wire to move following a complicated meandering and branched path such as a living body lumen. For example, in a conventional metal guide wire, tip flexibility is added by forming a tapered portion with a gradually decreasing outer diameter toward the tip side on a metal thin core material. On the other hand, since resin materials and glass materials are more likely to be damaged or worn during processing than metal materials, the desired taper shape is processed with high precision for thin materials made of resin materials and glass materials. It is not easy. For this reason, it has been difficult to impart tip flexibility to a guide wire using a resin material or a glass material, and it has been difficult to realize such a guide wire.

  SUMMARY OF THE INVENTION An object of the present invention is to provide a guide wire having a light-transmitting property and a tip flexibility that enables smooth movement in a living body lumen.

  The present invention can be achieved by the guide wire described in any of (1) to (4) below.

  (1) A medical guide wire having an elongated wire main body, wherein the wire main body is at least partially on the distal end side in the axial direction and intersects the axial direction of the wire main body. It has a light transmissive part having a light transmissive property capable of transmitting the irradiated light, the light transmissive part is made of a resin material or a glass material, and has a cross-sectional area of a cross section in the direction perpendicular to the axis. A guide wire having a lumen that is increased from the proximal side to the distal side.

  (2) The guide wire according to (1), wherein the light transmission portion includes a long member in which a lumen whose diameter continuously increases gradually from the proximal end side to the distal end side is formed.

  (3) The guide according to (1) or (2), wherein each of the light transmission parts includes a plurality of hollow members each having an inner cavity formed with a different diameter and connected to each other in the axial direction. Wire.

  (4) The guide according to any one of (1) to (3), wherein an antireflection material that prevents light reflection is provided on an outer surface of the light transmission portion and an inner surface of the lumen. Wire.

  According to the invention described in (1) above, the light emitted from a predetermined medical device to acquire a diagnostic image is transmitted through the light transmitting portion included in the guide wire, and the biological lumen side, the medical device side, Therefore, the back shadow is not reflected on the diagnostic image in the procedure using the guide wire. For this reason, it is possible to suitably diagnose a disease state or the like of a living body lumen based on the acquired examination image. In addition to this, the light transmission part has a lumen in which the cross-sectional area of the cross section in the direction perpendicular to the axis of the guide wire is increased from the proximal end side to the distal end side. Flexibility is provided. Therefore, it is possible to provide a guide wire that has light transparency and can realize smooth movement in a living body lumen.

  According to the invention described in (2) above, the light transmitting portion can be formed by the long member configured so that the diameter of the lumen gradually increases from the proximal end side to the distal end side. Thus, a guide wire configured to continuously increase flexibility can be provided.

  According to the invention described in (3) above, the light transmission part can be provided in the guide wire by a simple operation of connecting a plurality of hollow members each having a lumen formed with a different diameter. The manufacturing work of the guide wire having the flexibility and the tip flexibility can be simplified.

  According to the invention described in (4) above, since the antireflection material is provided on the outer surface of the light transmission part and the inner surface of the lumen, the light emitted from the predetermined medical device is reflected by the light transmission part. This can be prevented, and a clearer diagnostic image can be obtained when the guide wire is used.

It is a sectional view showing the whole guide wire composition concerning a 1st embodiment of the present invention. FIG. 2A is an enlarged cross-sectional view of a broken line portion 2A shown in FIG. 1 and FIG. 2B is an arrow 2B shown in FIG. 2A. It is an expanded sectional view which follows a -2B line. It is a figure which simplifies and shows the whole structure of the catheter apparatus used in order to image a diagnostic image. It is a figure which simplifies and shows the whole structure of the external drive device used in order to image a diagnostic image. It is a figure for demonstrating the effect | action of the guide wire which concerns on 1st Embodiment, Comprising: It is an expanded sectional view of the broken-line part 5A shown in FIG. It is sectional drawing which shows the whole structure of the guide wire which concerns on 2nd Embodiment of this invention. FIG. 7A is an enlarged cross-sectional view of a broken-line portion 7A shown in FIG. 1 and FIG. 7B is an arrow 7B shown in FIG. 7A. It is an expanded sectional view which follows a -7B line.

  Embodiments of the present invention will be described below with reference to the drawings. In addition, the dimension ratio of drawing is exaggerated on account of description, and may differ from an actual ratio.

<First Embodiment>
FIG. 1 and FIG. 2 are diagrams illustrating the configuration of each part of the guide wire according to the first embodiment, and FIG. 3 to FIG. 5 are diagrams for explaining a usage example of the guide wire according to the embodiment.

  Referring to FIG. 1, the guide wire 10 is a medical guide wire having a long wire main body portion 11, and the wire main body portion 11 is at least one on the distal end side in the axial direction. The light transmitting portion 20 is provided with a light transmitting property capable of transmitting light irradiated in a direction intersecting the axial direction of the wire main body portion 11. The light transmitting portion 20 is made of a resin material, and has a lumen 21 that changes so that the cross-sectional area of the cross section in the direction perpendicular to the axis increases from the proximal end side to the distal end side.

  In this specification, the left-right direction in FIG. 1, that is, the extending direction of the guide wire is referred to as the “axial direction”, the left side is referred to as the “front end side”, and the right side is referred to as the “base end side”. Further, “the distal end side of the wire main body portion” means a predetermined region on the distal end side of the wire main body portion 11, and an area including the most distal end portion 13 of the wire main body portion 11 or the most distal end portion of the wire main body portion 11. It means any region that does not include 13.

  The guide wire 10 according to the present embodiment is inserted into a living organ such as a living body lumen, and a medical instrument that allows a predetermined medical device to be introduced and guided to each part in the living body via the guide wire 10. It is. As said medical device, predetermined | prescribed information (data), such as an image, is detected by irradiating the predetermined | prescribed light (optical signal F) with respect to the biological organ used as object, and also detecting the reflected light, scattered light, etc. of the light. Is not particularly limited, for example, an optical coherence tomographic image diagnostic apparatus (OCT) for obtaining a diagnostic image, which will be described later, or an optical coherence tomography using a wavelength sweep that is an improved version thereof. A catheter apparatus 100 such as an image diagnostic apparatus (OFDI) may be mentioned (see FIG. 3). In addition, the living organ that is the target of use of the guide wire 10 is not particularly limited as long as the above-described medical device can be introduced. .

  As shown in FIG. 1, FIG. 2 (A), FIG. 2 (B), the wire main body portion 11 provided in the guide wire 10 has a long shape in which the entire shape is extended in the axial direction. Flexibility is provided so that it can deform | transform along shapes, such as a biological lumen. The outer surface of the wire main body 11 is formed smoothly from the distal end side to the proximal end side. For this reason, the outer diameter of the wire main-body part 11 is formed uniformly from the front end side to the base end side.

  The guide wire 10 includes a resin-made long member 30 having light transmissivity and a predetermined tip 40 attached to the long member 30. The wire body 11 is constituted by a long member 30. For this reason, the guide wire 10 has a configuration in which the guide wire 10 as a whole has optical transparency. In the description of the embodiment, for convenience, a portion where the lumen 21 is formed in the wire main body portion 11 is referred to as a light transmitting portion 20.

  The overall length of the wire main body 11 can be appropriately designed according to the intended use and purpose, and is not particularly limited. For example, the wire main body 11 can be formed to have a length of 1000 mm to 3500 mm. Further, the outer diameter of the wire main body 11 is not particularly limited as in the case of the length, but can be formed to be 0.2 mm to 0.5 mm, for example.

  As shown in FIG. 1 and FIG. 2 (A), the lumen 21 provided in the wire main body 11 is formed with a predetermined length from the most distal end portion 13 to the proximal end side of the wire main body 11. The lumen 21 is formed in a shape in which the diameter (inner diameter) continuously increases from the proximal end side to the distal end side. Since the thickness of the wire main body portion 11 becomes thinner toward the distal end side with respect to an arbitrary portion where the lumen 21 is formed in the wire main body portion 11, the flexibility of the wire main body portion 11 is increased. For this reason, the guide wire 10 is provided with a tip flexibility that gradually increases toward the tip side without processing a tapered shape on the outer surface like a conventional metal guide wire. .

  The position and length of the lumen 21 formed in the wire main body 11 are not particularly limited as long as the distal end flexibility of the guide wire 10 can be ensured. 13 to a length of 10 mm to 500 mm. Further, the diameter of the lumen 21 is not particularly limited as long as the flexibility of the distal end can be ensured and the breakage or the like is not caused in relation to the outer diameter of the guide wire 10, for example, The diameter of the most distal portion 13 where the diameter of the lumen 21 is maximum can be 0.19 mm to 0.49 mm, and the diameter of the minimum portion can be 0 mm to 0.35 mm.

  In the guide wire 10, the cross-sectional shape of the lumen 21 is formed in a circular shape, but this cross-sectional shape can be changed as long as the guide wire 10 can be provided with tip flexibility. For example, even if the cross-sectional shape is a rectangle, a rhombus, an ellipse or the like, the distal end of the guide wire 10 may be formed if the distal-side cross-sectional area is larger than the proximal-side cross-sectional area. Flexibility can be provided. For this reason, the cross-sectional shape of the lumen 21 is not limited to a circle. However, when the cross-sectional shape of the wire main body 11 is circular, it is preferable to form the cross-sectional shape of the lumen 21 in a circular shape in accordance with this shape. This is because such a configuration makes it possible to provide uniform tip flexibility at each portion in the circumferential direction of the wire main body portion 11.

  Examples of the resin material (resin material having optical transparency) constituting the wire main body 11 included in the guide wire 10 include PEEK (polyether ether ketone), polyolefin such as polyethylene, polyvinyl chloride, polystyrene, polyamide (example) : Nylon 6, nylon 46, nylon 66, nylon 610, nylon 612, nylon 11, nylon 12, nylon 6-12, nylon 6-66), polyimide, polycarbonate (PC), acrylic resin, other fluorine resin, styrene , Polyolefins, polyvinyl chlorides, polyurethanes, and other thermoplastic elastomers, epoxy resins, phenol resins, silicone resins, polyurethanes, etc., or copolymers, blends, polymer alloys, etc. mainly comprising these And this It can be used singly or in combination of two or more of.

  In the guide wire 10 according to the present embodiment, the long member 30 constituting the wire main body 11 is formed in a long shape so that any of the materials exemplified above is provided with a predetermined lumen 21. Is used. Although it does not specifically limit as a manufacturing method of the elongate member 30, For example, the injection molding method using a predetermined metal mold | die is employable.

  Moreover, the wire main-body part 11 is comprised with the member which has transparency and can be visually recognized from a part of the outer peripheral surface to the other side via a central axis. Here, “transparent” includes colorless and transparent as well as colored (colored) transparency.

  In addition, the wire main-body part 11 can also be comprised with the glass material provided with a light transmittance, for example. Examples of the glass material include quartz glass, alkali-free glass, soda glass, crystalline glass, potassium glass, and borosilicate glass.

  By using the resin material or the glass material as described above, the wire main body portion 11 has light permeability with respect to predetermined light emitted from the catheter device 100 described later. As a result, it is possible to suitably prevent the back shadow from being formed on the diagnostic image when the diagnostic image is acquired using the guide wire 10.

  The type of light that can be transmitted by the light transmitting unit 20 is, for example, near infrared light when used in the catheter device 100 or the like described later. However, the type of light that can be transmitted (wavelength of light) is changed according to the relationship with various medical devices and the like used together with the guide wire 10, and thus is limited to only near infrared light. There is nothing.

  As described above, in the guide wire 10, the wire main body 11 is made of a resin material having a light transmitting property, and thus the entire guide wire 10 has a light transmitting property. The part 20 should just be provided in at least one part of the front end side of the wire main-body part 11. FIG. For this reason, for example, a light transmitting portion 20 is formed using a resin material or glass material having light transmission properties at a part of the front end side or at a plurality of locations on the front end side, and other portions are not provided with light transmission properties. It is also possible to configure with materials or other materials. Examples of such materials include various metal materials such as stainless steel, Ni—Ti alloy, Ni—Al alloy, Cu—Zn alloy, and other superelastic alloys used in the conventional guide wire 10. Alternatively, a resin material having a relatively high rigidity can be used.

  The tip 40 provided at the most distal portion 13 of the wire main body 11 serves as a buffer member that prevents the living organs and the like from being damaged by the tip of the guide wire 10 when the guide wire 10 is introduced into the living body. It has a function. For the tip 40, for example, a tip having X-ray contrast properties can be used. By using the tip tip 40 having an X-ray contrast property, it becomes possible to confirm the position of the tip of the guide wire 10 during the procedure using the guide wire 10, so that the procedure can be performed more quickly and smoothly. Can proceed. It is also possible to connect a contrast coil to the tip chip 40. As a material constituting the tip 40, a known material having X-ray contrast properties such as Pt, Pt alloy, W, W alloy, Ag, and Ag alloy can be used.

  The outer shape of the tip 40 can be formed, for example, in a shape in which the tip is curved with a predetermined curvature as shown in the figure, as long as it is formed so as to reduce invasiveness to a living organ. It is possible to change. Further, the method for attaching the guide wire 10 to the tip can be appropriately selected from known methods such as adhesion, fusion, welding, and fitting according to the material of the wire main body 11 and the like.

  As shown in FIGS. 2A and 2B, an antireflection material 25 that prevents light reflection can be provided on the outer surface 24 of the light transmitting portion 20 and the inner surface 23 of the lumen 21.

  In the portion where the lumen 21 is formed in the light transmitting portion 20, light is refracted at the interface between the resin material or glass material constituting the light transmitting portion 20 and the lumen 21 adjacent to the light transmitting portion 20, and light is emitted. May be reflected. When the above-described reflection of light occurs when using the catheter device 100 described later, the reflected light becomes noise and it is difficult to acquire a clear diagnostic image. Therefore, by providing the antireflection material 25 on the outer surface 24 of the light transmitting portion 20 and the inner surface 23 of the lumen 21 of the light transmitting portion 20, the light is reflected when the predetermined light passes through the guide wire 10. Is prevented. In addition, the outer surface 24 of the light transmission part 20 is an outer surface of the position where the light transmission part 20 was formed in the wire main body part 11 in this embodiment.

  The antireflection material 25 provided on the inner surface 23 of the lumen 21 is preferably provided along the axial direction throughout the lumen 21. By providing the antireflection material 25 in the lumen 21 in this way, it is possible to more reliably prevent light from being reflected when predetermined light passes through the lumen 21.

  The range (length in the axial direction) of the outer surface 24 on which the antireflection material 25 is provided is not particularly limited as long as it is formed along at least the position where the lumen 21 is formed.

  The antireflection material 25 is not particularly limited as long as it can prevent light reflection and does not impair the light transmittance of the light transmitting portion 20. The well-known thing comprised by the coating material and film form provided with a function can be used. Moreover, when using the antireflective material which consists of a coating material, well-known methods, such as vacuum evaporation and sputtering, are employable as an application | coating method.

  As a specific material of the antireflection material 25, for example, an inorganic compound such as MgF 2 or SiO 2, a solution system using a fluororesin, or the like can be used. The antireflection material 25 may contain various coating agents that exhibit functions such as water / oil repellency, antifouling properties, fingerprint wiping properties, and slipperiness.

  The thickness dimensions of the antireflection material 25 provided on the outer surface 24 of the light transmitting portion 20 and the inner surface 23 of the lumen 2 are not particularly limited as long as the flexibility of the distal end of the guide wire 10 and the light transmittance of each portion are not impaired. However, for example, when the outer diameter of the guide wire 10 is formed to be about 0.2 mm to 0.5 mm, the thickness dimension at each portion can be formed to 0.01 mm to 0.49 mm, for example. .

  Next, usage examples and operations of the guide wire according to the present embodiment will be described.

  Prior to the description of the use example and operation of the guide wire, an outline of the catheter device 100 will be described. In addition, the structure of each part of the catheter apparatus 100 demonstrated below is an example, and the structure of each part can be changed.

  As shown in FIG. 3, the catheter device 100 includes a long catheter main body 110 that can be inserted into a living body lumen, and an operation unit 120 that is disposed on the user's hand side.

  The catheter device 100 is configured as an optical coherence tomography diagnostic apparatus (OCT) or an optical coherence tomography diagnostic apparatus (OFDI) using wavelength sweep. Near-infrared rays emitted from a prism 131 included in the imaging unit 130 described later are emitted to a living tissue (for example, an inner wall surface of a living body lumen) through a window 115 provided in the catheter main body 110. Then, after interference light is generated by causing reflected light from the biological tissue to interfere with predetermined reference light, a tomographic image (diagnosis image) of the biological lumen is drawn based on the interference light.

  As shown in FIG. 5, the catheter main body 110 has a guide wire insertion portion 111 extending to the distal end side thereof. The guide wire insertion portion 111 is disposed so that the central axis thereof is eccentric with respect to the central axis of the catheter body. That is, the catheter device 100 is configured as a so-called “rapid exchange type (short monorail type)” in which the guide wire 10 can be inserted and removed from the side of the catheter main body 110.

  As shown in FIG. 5, a working lumen 113 extending in the longitudinal direction is formed in the catheter main body 110. An imaging means 130 (described later) is inserted into the working lumen 113 so as to be movable back and forth in the axial direction.

  As shown in FIG. 5, an X-ray contrast marker 114 is provided at the distal end of the catheter main body 110 so that the position of the distal end can be confirmed during use. The X-ray contrast marker 114 is formed by spirally winding an element wire made of a radiopaque metallic material such as platinum.

  The tube wall at the distal end portion of the catheter main body 110 is configured as a window portion 115 that can transmit the optical signal F. This window part 115 can be comprised by the resin material or glass material provided with the light transmittance mentioned above, for example. An X-ray contrast marker may be provided around the window 115 so that the position of the window 115 can be confirmed when the catheter device 100 is used.

  The imaging means 130 includes an imaging core 133 configured by a prism 131 that transmits and receives an optical signal F to and from an inner wall surface of a living body lumen, and a housing 132 that houses the prism 131 therein, and the imaging core 133 is on the distal side. And a drive shaft 135 disposed at the same position.

  As the prism 131, for example, a right-angle prism 131 can be used. The prism 131 is fixed to the tip of the drive shaft 135. The fixing method is not particularly limited, and for example, it can be bonded by an adhesive or soldering.

  The drive shaft 135 has a function of transmitting the rotational force generated in the operation unit 120 to the imaging core 133. The imaging shaft 133 is rotated about the axis by the driving shaft 135 transmitting the rotational power. Thereby, a diagnostic image in the circumferential direction (360 ° direction) of the living body lumen can be acquired. An optical fiber 136 connected to the imaging core 133 is disposed in the drive shaft 135.

  As shown in FIG. 3, the operation unit 120 is connected to the hub 121 arranged on the proximal end side, the unit connector 126 connected to the hub 121 via the inner pipe 123, and the unit connector 126 via the outer pipe 125. The relay connector 127 is connected to connect the catheter body 110 and the operation unit 120.

  The drive shaft 135 and the inner tube 123 are held by the hub 121. When the inner tube 123 is pushed into or pulled out of the unit connector 126 and the outer tube 125, the drive shaft 135 is moved in the axial direction in the operation unit 120 and the working lumen 113 of the catheter body 110 in conjunction with this operation. It moves forward and backward (arrows a and b in FIG. 5 indicate the forward and backward movement of the drive shaft 135).

  A connection connector 128 connected to the proximal end portion of the drive shaft 135 is disposed on the proximal end side of the hub 121. The connection connector 128 is configured to include, for example, an optical fiber connector (not shown). The connection connector 128 is configured to be connectable and detachable to the scanner device 210 for rotating the drive shaft 135 at a high speed.

  FIG. 4 shows an overall configuration diagram of the external drive device 200 used when a predetermined diagnostic image is acquired using the catheter device 100.

  The external drive device 200 includes a scanner device 210 incorporating an external drive source such as a motor, a scanner device 210, an axial movement device 220 that moves the scanner device 210 back and forth in the axial direction by a motor or the like, and the scanner device 210. And a control unit 230 that controls the axial movement device 220 and a display unit 240 that displays an image obtained by the imaging core 133.

  The axial movement device 220 is provided with a scanner gripping portion 221 for gripping and fixing the scanner device 210 and a catheter support portion 222 that supports the catheter main body 110 so that the catheter main body 110 does not shift during movement.

  A connection connector 128 provided on the proximal end side of the hub 121 can be connected to the scanner device 210. The scanner device 210 transmits and receives a signal from the imaging core 133 and transmits a driving force for rotating the driving shaft 135.

  Scanning (scanning) in the catheter device 100 is transmitted and received by the imaging core 133 by transmitting the rotational motion of the motor in the scanner device 210 to the drive shaft 135 and rotating the housing 132 fixed to the tip of the drive shaft 135. This is performed by scanning an image in a substantially radial direction. The image obtained here is a tomographic image (cross-sectional image) of a living body lumen. Further, by pulling the entire catheter device 100 toward the hand side and moving the imaging core 133 in the axial direction, a tomographic image in the circumferential direction of the biological lumen at an arbitrary position in the axial direction of the biological lumen can be acquired. . The imaging result obtained by the imaging core 133 is transmitted to the external driving device 200, and then a predetermined process is performed in the control unit 230 and displayed as an image on the display unit 240.

  Next, the operation of the guide wire will be described.

  Referring to FIG. 5, when a predetermined diagnostic image is acquired using the catheter device 100, the guide wire 10 is inserted into the living body lumen in advance of the catheter device 100. As described above, since the guide wire 10 according to the present embodiment is provided with tip flexibility, the tip portion of the guide wire 10 can be smoothly and quickly moved to the target site in the living body. Next, the catheter body 110 is moved into the living body lumen along the guide wire 10. Then, while keeping the position of the guide wire 10 so as not to shift, the scanner device 210 moves the drive shaft 135 of the catheter device 100 around the axis and moves it in the proximal direction (the arrow in FIG. 5). b). Thereby, a tomographic image of the living body lumen can be acquired.

  As described above, since the window portion 115 of the catheter body 110 is configured to have light transmittance, the optical signal F emitted from the prism 131 disposed on the drive shaft 135 is transmitted through the window portion 115. To do. The optical signal F that has passed through the window 115 is applied to the guide wire 10 in a direction that intersects the axial direction of the guide wire 10. The direction intersecting with the axial direction means at least one of all directions passing through the central axis of the guide wire 10.

  Then, the optical signal F passes through the light transmission part 20 of the guide wire 10 and reaches the inner wall surface of the living body lumen. Thereafter, the light is reflected by the inner wall surface of the living body lumen and becomes reflected light. The reflected light is again transmitted through the light transmitting portion 20 of the guide wire 10 and the window portion 115 of the catheter main body 110 and received by the prism 131 disposed on the drive shaft 135. As described above, since the optical path of the optical signal F applied to the guide wire 10 can be prevented from being blocked by the guide wire 10, it is possible to prevent the occurrence of back shadow.

  As described above, according to the guide wire 10 according to the present embodiment, the optical signal F emitted from the catheter device 100 in order to acquire a diagnostic image passes through the light transmission unit 20 included in the guide wire 10 and is living. Since it moves back and forth between the lumen side and the catheter device 100 side, back shadow does not appear on the diagnostic image in the procedure using the guide wire 10. For this reason, it is possible to suitably diagnose a disease state or the like of a living body lumen based on the acquired examination image. In addition to this, the light transmitting portion 20 is formed with a lumen 21 in which the cross-sectional area of the guide wire 10 in the direction perpendicular to the axis is changed from the proximal end side to the distal end side. 10 is provided with tip flexibility. Therefore, it is possible to provide the guide wire 10 that has optical transparency and can realize smooth movement in the living body lumen.

  Further, since the light transmitting portion 20 is formed by the long member 30 configured so that the diameter of the lumen 21 gradually increases from the proximal end side to the distal end side, the flexibility continuously increases toward the distal end side. A guidewire 10 configured to do so can be provided.

  Further, since the antireflection material 25 is provided on the outer surface 24 of the light transmission part 20 and the inner surface 23 of the lumen 21, the optical signal F emitted from the catheter device 100 is prevented from being reflected by the light transmission part 20. When the guide wire 10 is used, a clearer diagnostic image can be acquired.

Second Embodiment
Next, a guide wire according to a second embodiment of the present invention will be described. The same members as those of the guide wire according to the first embodiment described above are denoted by the same reference numerals, and description thereof is omitted.

  FIG. 6 is a cross-sectional view showing the overall configuration of the guide wire according to the present embodiment.

  In the above-described guide wire 10 according to the first embodiment, the light transmitting portion 20 capable of transmitting predetermined light has a long length in which a lumen 21 whose diameter continuously increases from the proximal end side to the distal end side is formed. It was comprised by the member 30. On the other hand, in the guide wire 50 according to the present embodiment, light is emitted by a plurality of hollow members 70, 80, 90 having inner cavities 71, 81, 91 having mutually different diameters and mutually connected in the axial direction. A transmission unit 60 is configured. Hereinafter, this embodiment will be described in detail.

  As shown in FIG. 6, a light transmission portion 60 including a plurality of hollow members 70, 80, 90 is provided on the distal end side of the wire main body 51 provided in the guide wire 50. In the present embodiment, the first to third hollow members 70, 80, 90 in which lumens 71, 81, 91 having predetermined diameters are formed are used. Although the length of each hollow member 70, 80, 90 can be changed according to the full length of the guide wire 50, it can form in 10 mm-300 mm, respectively, for example. The diameters of the lumens 71, 81, 91 are not particularly limited, but the diameter of the lumen 71 of the first hollow member 70 is 0.2 mm to 0.5 mm, and the lumen 81 of the second hollow member 80. Can be formed with a diameter of 0.1 mm to 0.3 mm, and the diameter of the lumen 91 of the third hollow member 90 can be set to 0 mm to 0.2 mm. As described above, the third hollow member 90, the second hollow member 80, and the first hollow member 70 are arranged side by side in the axial direction in order from the proximal end side of the guide wire 50, whereby the flexibility of the guide wire 50 is increased. Can be gradually increased from the proximal end side to the distal end side.

  As a material constituting each of the hollow members 70, 80, 90, the resin material or glass material having the light transmittance described in the first embodiment described above can be used. As a manufacturing method, it is possible to employ a method in which the hollow members 70, 80, 90 made of these resin resin materials and glass materials are arranged in the axial direction and connected by a known method such as fusion, adhesion, or welding. it can. The light transmitting portion 60 is formed by the connected hollow members 70, 80, 90, and the lumen 61 of the light transmitting portion 60 is formed by the lumens 71, 81, 91 arranged so as to extend in the axial direction. It is formed.

  The number of hollow members used for the guide wire 50 is not limited to three as shown in the figure. For example, two hollow members having different lumen diameters or four different lumen diameters are used. It is also possible to use the above hollow members. It is also possible to use a different resin material or glass material for each hollow member.

  In the guide wire 50 according to the present embodiment, a solid long member made of first to third hollow members 70, 80, 90 and a metal wire disposed on the proximal end side of the third hollow member 90. 62 constitutes a wire main body 51. The 3rd hollow member 90 and the elongate member 62 can be connected by well-known methods, such as melt | fusion, adhesion | attachment, and welding mentioned above. In addition, it is also possible to comprise parts other than the light transmission part 60 with the resin material provided with a light transmittance, and another material.

  Further, as shown in FIGS. 7A and 7B, the antireflection material 25 can be provided on the inner surface 23 of the inner cavity 61 of the light transmitting portion 60 and the outer surface 24 of the light transmitting portion 60. The point that the tip tip 40 can be attached to the tip, the cross-sectional shape of the lumens 71, 81, 91 of each hollow member 70, 80, 90 is not limited to a circle, etc., are the same as the guide wire 10 according to the first embodiment. It is the same.

  Since the guide wire 50 described in the present embodiment is configured to have optical transparency and tip flexibility like the guide wire 10 according to the first embodiment, the guide wire 50 is used together with a predetermined medical device. Therefore, there is no risk of causing back shadow on the examination image, and smooth movement in the living body lumen can be realized. In addition, since the use procedure etc. when using the guide wire 50 for OCT and OFDI are the same as the case where the guide wire 10 which concerns on 1st Embodiment is used, the description is abbreviate | omitted. In addition, since the light transmission portion 60 can be provided in the guide wire 50 by a simple operation of connecting the plurality of hollow members 70, 80, 90 each having the lumens 71, 81, 91 formed with different diameters, The manufacturing operation of the guide wire 50 having light transmittance and tip flexibility can be simplified. In addition to this, when the guide wire 50 is used, the entire guide wire 50 is bent since each of the connecting portions where the hollow members 70, 80, 90 are connected to each other is a starting point of bending. It is possible to further improve the followability to a steep branch or a meandering path existing in a lumen or the like.

  As described above, the guide wire according to the present invention has been described through the embodiments. However, the guide wire according to the present invention is not limited to the configuration described in the embodiments, and various types can be made based on the description of the claims. It is possible to modify.

  For example, it is possible to provide the guide wire with a light transmission portion by combining the long member described in the first embodiment and the hollow member described in the second embodiment. Specifically, a plurality of hollow members in which a part of the wire main body portion is constituted by a long member, and lumens having a diameter larger than the diameter of the lumen of the long member are formed on the distal end side of the long member. Or a plurality of hollow members each having a diameter smaller than the diameter of the lumen of the long member is connected to the proximal end side of the long member to constitute the light transmitting portion. be able to. By using a combination of a long member and a hollow member in this way, it becomes possible to finely adjust the flexibility of the tip, etc., so it is possible to provide a wider variety of guide wires with different product specifications become.

  This application is based on Japanese Patent Application No. 2013-182397 filed on September 3, 2013, the disclosure of which is incorporated by reference in its entirety.

10, 50 guide wire,
11, 51 wire body,
20, 60 light transmission part,
21, 61 lumen,
23 inner surface of the lumen,
24 The outer surface of the light transmission part,
25 anti-reflective material,
30 long member,
70 first hollow member,
71 the lumen of the first hollow member;
80 a second hollow member,
81 the lumen of the second hollow member;
90 third hollow member,
91 the lumen of the third hollow member;
100 catheter device,
200 External drive.

Claims (4)

A medical guide wire having an elongated wire body,
The wire main body portion has a light transmission portion having a light transmission property capable of transmitting light irradiated in a direction intersecting the axial direction of the wire main body portion at least at a part of the tip end side in the axial direction. ,
The light transmission part is a guide wire made of a resin material or a glass material, and having a lumen that changes so that the cross-sectional area of the cross section in the direction perpendicular to the axis increases from the proximal end side to the distal end side.   2. The guide wire according to claim 1, wherein the light transmission part has a long member in which a lumen whose diameter continuously increases gradually from a proximal end side to a distal end side is formed.   3. The guide wire according to claim 1, wherein each of the light transmission parts includes a plurality of hollow members each having an inner cavity formed with a diameter different from each other and connected to each other in the axial direction.   The guide wire according to any one of claims 1 to 3, wherein an antireflection material for preventing light reflection is provided on an outer surface of the light transmission portion and an inner surface of the lumen.