JPWO2005097152A1 - Turmeric extract-containing composition with improved caking properties - Google Patents

Abstract

Regarding the use of turmeric extract with extremely useful physiological action, by improving undesirable properties such as causticity due to the high viscosity oil of turmeric extract, poor fluidity and adhesion to containers, etc. Thus, the present invention provides a composition containing a high concentration of turmeric extract which is extremely difficult to handle as it is. Using a turmeric extract-containing composition characterized by comprising a turmeric extract in excess of 40% by weight and comprising a fat and oil and / or a lipophilic emulsifier having an HLB value of 8.5 or less, Useful components are encapsulated in soft capsules at high concentrations.

Description

  The present invention relates to a turmeric extract-containing composition with improved caking properties that facilitates the use of a turmeric extract having an effect of preventing or improving multiple risk factor syndrome.

  Turmeric (Spring turmeric: Curcuma aromatica, fall turmeric: Curcuma longa), which is classified into the genus Turmeric genus, is generally known as turmeric, one of the curry spices, and is widely used for food. On the other hand, traditional therapies such as Chinese herbal medicine, Ayurveda in India, and Jamu in Indonesia have long been known to have hemostatic, stomachic, antibacterial and anti-inflammatory effects and are also used as medicinal products. ing. In addition, attention is paid to the effects of turmeric and the main component curcumin. Antioxidant action, bile secretion promoting action (biliary action), visceral (liver, pancreas) function enhancing action, carcinogenesis suppressing action, lipid metabolism improving action, whitening action, etc. Physiological effects have been clarified. Furthermore, it is known that the turmeric extract has an effect of preventing or ameliorating multiple risk factor syndromes such as visceral fat obesity, diabetes, hyperlipidemia, hypertension and the like (International Publication No. 02 / 47699 pamphlet), turmeric is a very useful material having various functions.

  However, the turmeric extract (turmeric oleoresin) contains terpenes such as bisaborane-type sesquiterpenes in addition to curcumin and curcumin derivatives (curcuminoids), so its properties are highly viscous oily and caking. Due to the poor fluidity and the problem of adhesion to containers and the like, it is extremely difficult to handle as it is, and for example, it is extremely difficult to enclose it in a soft capsule or the like. In addition, it is difficult to dissolve in water and triglycerides, and the use of the turmeric extract has been made difficult, such as the use of alcohol or ketone-based organic solvents to make a solution. In the above-mentioned pamphlet of International Publication No. 02/47699, there is a description of soft capsules using turmeric extract (turmeric extract 40 parts by weight, sesame oil 55 parts by weight, glycerin fatty acid ester 5 parts by weight). There is no description regarding the properties of the extract, and there is no specific mention about the details of the emulsifier incorporated, and actually using Emulsy MS (manufactured by Riken Vitamin Co., Ltd., HLB = 4.3) as the glycerin fatty acid ester. As a result of the evaluation of caking properties, it was possible to make soft capsules at the laboratory level, but industrially, the caking properties were not practical for making soft capsules. Therefore, it is clear that no suggestion is given to the present invention.

  As a means for solving such problems when using the turmeric extract, a mixture of turmeric extract and zein has been proposed (Japanese Patent Laid-Open No. 9-111282). According to this method, it is possible to obtain a non-caking solid at room temperature, but the turmeric extract content is limited to about 50%. In addition, since an organic solvent such as water-containing ethanol is used in the manufacturing process and a process for drying the solution is required, the product must be expensive.

In addition, extraction from turmeric powder with edible fats and oils or diglycerides has also been proposed (JP 2001-86931 A, JP 2003-137799 A). According to this method, it is possible to obtain an oil containing an active ingredient of turmeric, but the concentration is not as high as in the present invention, and is only about 1% in terms of curcumin concentration. In order to obtain the action, the oil was consumed in a large amount, which was not practical.
International Publication No. 02/47699 JP-A-9-111282 JP 2001-86931 A JP 2003-137799 A

  The object of the present invention relates to the use of a turmeric extract having a very useful physiological action, and solves the problems of poor fluidity and adhesion to containers, etc. by improving the above-mentioned undesirable properties. The object is to provide a composition containing a difficult-to-handle turmeric extract in a high concentration.

  In view of the above situation, as a result of intensive studies, the present inventors have significantly improved caking properties by mixing turmeric extract with edible oils and fats and / or specific emulsifiers, and contain turmeric extract at a high concentration. The present inventors have found that a slurry having good fluidity can be obtained and completed the present invention.

  That is, the first of the present invention comprises a turmeric extract containing more than 40% by weight and comprising a medium-chain fatty acid triglyceride and / or fat and / or a lipophilic emulsifier having an HLB value of 8.5 or less. The present invention relates to a turmeric extract-containing composition. A preferred embodiment relates to the turmeric extract-containing composition as described above, comprising a medium-chain fatty acid triglyceride and / or a lipophilic emulsifier having an HLB value of 8.5 or less. More preferably, the turmeric extract-containing composition as described above, wherein the lipophilic emulsifier is a glycerin fatty acid ester, and more preferably, the turmeric as described above, wherein the lipophilic emulsifier is a polyglycerol fatty acid ester. Extract-containing composition, particularly preferably the constituent fatty acid of polyglycerol fatty acid ester is an unsaturated fatty acid, the turmeric extract-containing composition as described above, very preferably the lipophilic emulsifier is diglycerol monooleate The turmeric extract-containing composition as described above, characterized in that, most preferably, the turmeric extract-containing composition as described above, which has an effect of preventing or improving multiple risk factor syndrome .

  The second of the present invention relates to a capsule encapsulating the above-described composition.

  In spite of containing the turmeric extract at a high concentration, it is possible to provide a composition having a low viscosity and low adhesion to a container or the like. Therefore, for example, it becomes easy to enclose a useful component of turmeric in a soft capsule or the like at a high concentration.

The turmeric extract-containing composition of the present invention is a highly concentrated turmeric extract that has extremely useful physiological activity, but has a problem of high viscosity, caking property, poor fluidity, and high adhesion to containers. By mixing medium chain fatty acid triglycerides and / or fats and oils and / or lipophilic emulsifiers having an HLB value of 8.5 or less, there is an advantage of excellent fluidity, adhesion and uniformity. Moreover, since the turmeric extract containing composition of this invention contains a high concentration turmeric extract, it has the advantage that it has the effect of preventing or improving a multiple risk factor syndrome. Furthermore, since the composition containing turmeric extract of the present invention is excellent in fluidity, adhesion and uniformity, it has an advantage that a soft capsule encapsulating a high concentration of turmeric extract can be easily produced.

  The present invention is described in detail below. The turmeric extract containing composition of this invention mix | blends the fats and oils component which improves fluidity, and / or the lipophilic emulsifier which improves caking property with respect to a turmeric extract.

  The production method of the turmeric extract of the present invention is not particularly limited, and can be obtained by a conventionally known method, for example, a method of extracting the rhizome part of turmeric with warm ethanol. Commercially available turmeric oleoresin can also be used as it is.

  Furthermore, the turmeric extract used in the present invention includes curcumin, curcumin derivatives (for example, demethoxycurcumin, bisdemethoxycurcumin, dihydrocurcumin, tetrahydrocurcumin, hexahydrocurcumin, dihydroxytetracurcumin, etc.) and bisaborane-type sesquiterpenes, For example, it contains β-bisaborane, α-curcumene, gingiberene, β-sesquiferlandene, ar-turmerone, α-turmerone, β-turmerone and the like.

  The medium chain fatty acid triglyceride (hereinafter also referred to as MCT) used in the present invention is a triglyceride having a fatty acid residue having 6 to 10 carbon atoms as a constituent fatty acid residue.

  The fats and oils used in the present invention are edible fats and oils other than medium-chain fatty acid triglycerides, and there is no particular limitation other than that. For example, corn oil, rapeseed oil, Haieru rapeseed oil, soybean oil, olive oil, safflower oil, cottonseed oil, sunflower oil, rice bran oil, palm oil, palm kernel oil and other vegetable oils, fish oil, beef tallow, pork fat, milk fat, egg yolk oil Animal oils such as these, oils and fats that have been subjected to fractionation, hydrogenation, transesterification, etc. using these as raw materials, or mixed oils thereof can be used. Moreover, if it is uses other than foodstuff, it is also possible to select fats and oils other than the said animal and vegetable fats and oils.

  The lipophilic emulsifier used in the present invention is not particularly limited as long as it can be uniformly mixed with the turmeric extract or the turmeric extract and the oil and fat, but the HLB value is preferably 8.5 or less, more preferably 3 to 8.5, and still more preferably. Is 5 to 8.5. This is because it is preferable that the solvent used in the extraction of turmeric is close to the lipophilicity. However, the term “lipophilic” as used herein means that it is soluble in fats and oils, and those that are soluble in MCT and general edible fats and oils are used as lipophilic emulsifiers. When the HLB value exceeds 8.5, the turmeric extract, the oil and fat, and the emulsifier may be separated.

  The HLB value is a scale generally indicating the degree of hydrophilicity and lipophilicity of an emulsifier, and the smaller the value, the stronger the lipophilicity. The method for obtaining the HLB value is not particularly limited. For example, the HLB value can be obtained by the following formula (see Chemical Dictionary, Tokyo Chemical Doujin, 1st edition, issued on October 1, 1994).

HLB = 20 × (1-S / A)
S: Saponification value of ester, A: Acid value of fatty acid Examples of such an emulsifier include glycerin fatty acid esters such as monoglycerin fatty acid ester, monoglycerin fatty acid organic acid ester, polyglycerin fatty acid ester, and polyglycerin condensed ricinoleic acid ester. , Sorbitan fatty acid esters, polysorbates, sucrose fatty acid esters, propylene glycol fatty acid esters, lecithins and the like, and at least one of them can be used in combination. Among these, glycerin fatty acid esters are preferable because the caking property can be effectively improved, and polyglycerin fatty acid esters and polyglycerin condensed ricinoleic acid esters are more preferable. The caking property referred to in the present invention means a balance between fluidity, adhesion to a container, and uniformity of each component of the turmeric extract-containing composition. Means good.

  Examples of the polyglycerin fatty acid ester and the polyglycerin condensed ricinoleic acid ester include those having an average degree of polymerization of polyglycerin of 2 to 10. Furthermore, the polyglycerin fatty acid ester is exemplified by fatty acids having 6 to 22 carbon atoms in the constituent fatty acid. Among them, the constituent fatty acid is preferably an unsaturated fatty acid, for example, diglycerin monooleate, tetraglycerin penta Preferred are oleic acid ester, hexaglycerin pentaoleic acid ester, pentaglycerin trioleic acid ester, decaglycerin pentaoleic acid ester, decaglycerin dekaoleic acid ester, decaglycerin decaerucic acid ester, and more preferably diglycerin. Monooleate.

  If the said MCT, fats and oils, and the lipophilic emulsifier whose HLB value is 8.5 or less can be mixed uniformly with a turmeric extract, at least 1 sort (s) of them can be used. As the content of the turmeric extract increases, a lipophilic emulsifier having an MCT and / or HLB value of 8.5 or less is preferable, and a mixture of a lipophilic emulsifier having an MCT and HLB value of 8.5 or less is more preferable. MCT has a low viscosity compared to general fats and oils and is known to have a body fat suppression effect. Compared with general fats and oils, MCT has a uniform and fine slurry, and thus has a large effect of improving fluidity and uniformity. A lipophilic emulsifier having an HLB value of 8.5 or less has a great effect of improving adhesion.

  Here, the content of the turmeric extract and the medium-chain fatty acid triglyceride and / or fat and oil and / or the lipophilic emulsifier having an HLB value of 8.5 or less in the turmeric extract-containing composition will be described in detail. The medium-chain fatty acid triglycerides and / or fats and / or fats and / or lipophilic emulsifiers having an HLB value of 8.5 or less are MCT alone, fats and oils alone, lipophilic emulsifiers having an HLB value of 8.5 or less, Combined use of MCT and oil, combined use of MCT and lipophilic emulsifier having an HLB value of 8.5 or less, combined use of fat and oil and lipophilic emulsifier having an HLB value of 8.5 or less, MCT, fat and oil and HLB value of 8.5 Use in combination with the following lipophilic emulsifiers. These combinations can be appropriately selected depending on the content of the turmeric extract.

  That is, when the content of the turmeric extract in the turmeric extract-containing composition is 40% by weight or less, the MCT and / or fat and oil and / or the lipophilic emulsifier having an HLB value of 8.5 or less is 60% by weight or more. In this case, MCT alone, fat and oil alone, lipophilic emulsifier alone, combined use of MCT and fat and oil, combined use of MCT and lipophilic emulsifier, combined use of fat and oil and lipophilic emulsifier, combined use of MCT, fat and oil and lipophilic emulsifier, A combination of

  Similarly, when the content of turmeric extract is more than 40% by weight and less than 50% by weight, MCT alone, lipophilic emulsifier alone, combined use of MCT and fat, combined use of MCT and lipophilic emulsifier, fat and fat and lipophilic Any combination of emulsifiers, MCT, fats and oils and lipophilic emulsifiers may be used, and the total amount is in the range of more than 50% by weight and less than 60% by weight. Since the effect of improving the caking property may not be practical when the oil or fat is used alone, the combined use with MCT or the combined use of the lipophilic emulsifier is preferable, and the weight ratio of the oil and fat to the lipophilic emulsifier is 99.9 / 0.1 0.1 / 99.9 is preferable, and 90/10 to 0.1 / 99.9 is more preferable. When giving priority to fluidity, it is preferable to set the ratio of fats and oils high, and when giving priority to improving adhesion, the weight ratio of the lipophilic emulsifier is preferably set high.

  When the content of turmeric extract is 50 wt% or more and less than 60 wt%, MCT alone, lipophilic emulsifier alone, combined use of MCT and fat, combined use of MCT and lipophilic emulsifier, fat and lipophilic emulsifier Or a combination of MCT, fats and oils, and a lipophilic emulsifier, any combination may be used, and the total amount is in the range of more than 40% by weight and 50% by weight or less. Since fats and oils alone may not have sufficient caking improvement effect, the combined use of fats and fats or MCT or the combination of fats and fats and lipophilic emulsifiers is preferred, and when trying to achieve great improvements in both fluidity and adhesion The combined use of MCT and a lipophilic emulsifier is more preferred. In the case of the combined use of fats and oils and lipophilic emulsifiers, the weight ratio of fats and fats and lipophilic emulsifiers is preferably 90/10 to 0.1 / 99.9, more preferably 75/25 to 0.1 / 99.9. The content ratio of the emulsifier is higher than when the content of the turmeric extract is more than 40% by weight and less than 50% by weight. 90/10 to 0.1 / 99.9 is preferable, and the weight ratio of oil and MCT in the case of the combined use of oil and fat and MCT is more preferably 70/30 to 0.1 / 99.9, still more preferably 50. / 50 to 0.1 / 99.9, and the MCT ratio is set to a higher range than when the content of the turmeric extract is more than 40% by weight and less than 50% by weight. When giving priority to fluidity, it is preferable to set the ratio of fats and oils high, and when giving priority to improving adhesion, the weight ratio of the lipophilic emulsifier is preferably set high. Further, the weight ratio of MCT and lipophilic emulsifier in the combined use of MCT and lipophilic emulsifier is preferably 90/10 to 10/90. Within this range, both fluidity and adhesion are greatly improved.

  Furthermore, when the content of turmeric extract is 60% by weight or more, the combined use of MCT and lipophilic emulsifier, the combined use of fat and oil and lipophilic emulsifier, the combined use of MCT, fat and oil and lipophilic emulsifier is preferable. And a lipophilic emulsifier are more preferred, and the total amount is 40% by weight or less. When MCT and a lipophilic emulsifier are used in combination, the weight ratio of MCT to the lipophilic emulsifier is not particularly limited, but is preferably 0.1 / 99.9 to 99.9 / 0.1, more preferably 10/90 to 90. / 10, more preferably 25/75 to 75/25, most preferably in the range of 40/60 to 60/40. When fluidity is prioritized, the ratio of fats and oils is increased, and improvement of adhesion is prioritized. In this case, it is preferable to set the weight ratio of the lipophilic emulsifier high.

  Adjustment of the turmeric extract-containing composition is preferably performed under heating conditions as necessary, and more preferably adjusted at about 20 to 60 ° C. Specifically, for adjustment, a predetermined amount of turmeric extract and a predetermined amount of oil and / or lipophilic emulsifier may be uniformly mixed by stirring under a heating condition at a predetermined temperature. For example, a paddle mixer , Homomixers, homogenizers, high-pressure homogenizers, colloid mills, bead mills, and the like can be used.

  The turmeric extract-containing composition prepared by the above-described method can be added to food as it is, but it is preferably in a capsule form in order to take it more effectively, for example, soft capsule, hard capsule, Seamless capsules can be used. In addition, various vitamins such as vitamins A, C, D, and E, and pharmaceutical preparations such as beeswax may be further added to the turmeric extract composition according to the purpose. In addition, licorice hydrophobic extract, clove extract, cinnamon extract, etc. that have the effect of preventing or improving multiple risk factor syndrome, or materials commonly used as food, and food additives such as antioxidants are added May be.

  EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated further more concretely, this invention is not limited to these Examples.

<Fluidity evaluation method>
20 g of the turmeric extract-containing composition was put into a 50 cc glass beaker, and the state when the beaker was tilted downward 45 degrees at 25 ° C. was observed. The evaluation criteria are as follows.
◎: Flows out quickly, ○: Flows out slowly, △: Flows out slowly when heated to 40 ° C, X: Almost does not flow even when heated to 40 ° C, *: Emulsifier does not become uniform even when stirred Cannot be evaluated in a separated state.

<Adhesion evaluation method>
20 g of the turmeric extract-containing composition was put into a 50 cc glass beaker, and the beaker was tilted downward 45 degrees at 25 ° C., then the beaker was returned to its original state and the state of the inner wall of the beaker after standing for 30 minutes was observed. The evaluation criteria are as follows. ◎: No adhesion to the inner wall, ○: Slight adhesion to the inner wall, △: Grainy adhesion to the inner wall, ×: Sticky to the inner wall, *: Even after stirring, the emulsifier did not become uniform and separated Cannot be evaluated by condition.

<Uniformity evaluation method>
The appearance and internal phase of the turmeric extract-containing composition were observed. The evaluation criteria are as follows. A: Uniform and fine slurry state, ○: Uniform but granular slurry state, Δ: Uniform when stirred, but solid and liquid separated in a short time after standing, X: Even when stirred The emulsifier is not uniform and separated.

(Example 1)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd .: 31% curcuminoid and 39% terpene) 50% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 25% by weight, diglycerin monooleate (RIKEN) Vitamin Co., Ltd., trade name: Poem DO-100V, HLB value = 8.0) 25% by weight was mixed with a paddle mixer under 40 ° C. heating conditions. The obtained turmeric extract-containing composition showed very good properties with greatly improved flowability, adhesion and uniformity, ie, greatly improved caking properties (Table 1).

(Example 2)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 50% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 37.5% by weight, diglycerin monooleate (manufactured by Riken Vitamin Co., Ltd., trade name: (Poem DO-100V, HLB value = 8.0) 12.5% by weight was mixed by a paddle mixer under heating at 40 ° C. The obtained turmeric extract-containing composition showed very good properties with greatly improved flowability, adhesion and uniformity, ie, greatly improved caking properties (Table 1).

(Example 3)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 50% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 12.5% by weight, diglycerin monooleate (manufactured by Riken Vitamin Co., Ltd., trade name: (Poem DO-100V, HLB value = 8.0) 37.5% by weight was mixed with a paddle mixer under heating at 40 ° C. The obtained turmeric extract-containing composition showed very good properties with greatly improved flowability, adhesion and uniformity, ie, greatly improved caking properties (Table 1).

Example 4
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 80% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 10% by weight, diglycerin monooleate (manufactured by Riken Vitamin Co., Ltd., trade name: Poem DO 10% by weight of −100 V, HLB value = 8.0), and mixed by a paddle mixer under heating at 40 ° C. The obtained turmeric extract-containing composition showed good properties with improved flowability and adhesion, and greatly improved uniformity, ie, improved caking properties (Table 1).

(Example 5)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 50% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2), 5% by weight, pentaglycerin trioleate (manufactured by Taiyo Kagaku Co., Ltd., trade name: Sun Fat) A-173E, HLB value = 7.0) 45% by weight, and mixed by a paddle mixer under heating at 40 ° C. The resulting turmeric extract-containing composition showed good properties with improved flowability, greatly improved adhesion and uniformity, and improved caking properties (Table 1).

(Example 6)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 50% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 45% by weight, hexaglycerin pentaoleate (manufactured by Sakamoto Pharmaceutical Co., Ltd., trade name: SY Glister PO-5S, HLB value = 4.9) 5% by weight was mixed with a paddle mixer under heating at 40 ° C. The obtained turmeric extract-containing composition showed good properties with greatly improved fluidity and uniformity, improved adhesion, and improved caking (Table 1).

(Example 7)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 45% by weight and MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 55% by weight were mixed with a paddle mixer under 40 ° C. heating conditions. The obtained turmeric extract-containing composition showed good properties with greatly improved fluidity, improved adhesion and uniformity, and improved caking properties (Table 1).

(Example 8)
Using 40% by weight of turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 45% by weight and 55% by weight of diglycerin monooleate (manufactured by Riken Vitamin Co., Ltd., trade name: Poem DO-100V, HLB value = 8.0) It mixed with the paddle mixer under the heating condition. The obtained turmeric extract-containing composition showed good properties with improved fluidity and uniformity, greatly improved adhesion, and improved caking (Table 1).

Example 9
After uniformly mixing 300 mg of the turmeric extract-containing composition of Example 1 and 30 mg of beeswax, the mixture was press-fitted into the gelatin film using a rotary type soft capsule manufacturing apparatus to obtain a soft capsule having an internal volume of 330 mg. It was confirmed that the remaining amount of the contents due to adhesion in the blending tank and the soft capsule manufacturing apparatus was very small, and there was no problem industrially.

(Comparative Example 1)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 50% by weight, MCT (manufactured by Riken Vitamin Co., Ltd., trade name: Actor M2) 25% by weight, tetraglycerin monooleate (manufactured by Sakamoto Pharmaceutical Co., Ltd., trade name: SY (Glister MO-3S, HLB value = 8.8) 25% by weight was mixed with a paddle mixer under heating at 40 ° C. The obtained turmeric extract-containing composition was in a non-uniform state because the emulsifier was separated, and the fluidity and adhesion could not be evaluated (Table 1).

(Comparative Example 2)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 40% by weight, sesame oil (manufactured by Kadoya Oil Co., Ltd.) 55% by weight, monoglycerin monostearate (manufactured by Riken Vitamin Co., Ltd., trade name: Emulsy MS, HLB value = 4. 3) Using 5% by weight, the mixture was mixed by a paddle mixer under heating at 40 ° C. The obtained turmeric extract-containing composition had improved fluidity but not much improved adhesion and uniformity, and the caking improvement was not necessarily sufficient (Table 1). Further, when soft capsules were prepared in the same manner as in Example 9, a considerable amount of adhesion was confirmed in the preparation tank and the soft capsule manufacturing apparatus, and it was confirmed that there was an industrial problem.

(Comparative Example 3)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 45% by weight and rapeseed oil (manufactured by Kaneka Chemical Co., Ltd.) 55% by weight were mixed with a paddle mixer under 40 ° C. heating conditions. The obtained turmeric extract-containing composition was not improved so much in fluidity, adhesion, and uniformity, and the caking improvement was not necessarily sufficient (Table 1).

(Comparative Example 4)
Turmeric oleoresin (manufactured by Maruzen Pharmaceutical Co., Ltd.) 100% by weight, that is, the fluidity and adhesion were considerably poor by themselves.

In spite of containing the turmeric extract at a high concentration, it is possible to provide a composition having a low viscosity and low adhesion to a container or the like. Therefore, for example, it becomes easy to enclose a useful component of turmeric in a soft capsule or the like at a high concentration.

Claims (8)

A turmeric extract-containing composition comprising more than 40% by weight of a turmeric extract and comprising a medium-chain fatty acid triglyceride and / or fat and oil and / or a lipophilic emulsifier having an HLB value of 8.5 or less . The turmeric extract-containing composition according to claim 1, comprising a medium-chain fatty acid triglyceride and / or a lipophilic emulsifier having an HLB value of 8.5 or less. The turmeric extract-containing composition according to claim 1 or 2, wherein the lipophilic emulsifier is a glycerin fatty acid ester. The turmeric extract-containing composition according to claim 1 or 2, wherein the lipophilic emulsifier is a polyglycerol fatty acid ester. The turmeric extract-containing composition according to claim 4, wherein the constituent fatty acid of the polyglycerol fatty acid ester is unsaturated. The turmeric extract-containing composition according to claim 1 or 2, wherein the lipophilic emulsifier is diglycerin monooleate. The turmeric extract-containing composition according to claim 1, which has an effect of preventing or improving multiple risk factor syndrome. A capsule formed by encapsulating the composition according to claim 1.