JPS6463518A - Antiarrhythmic agent - Google Patents
Antiarrhythmic agentInfo
- Publication number
- JPS6463518A JPS6463518A JP62221142A JP22114287A JPS6463518A JP S6463518 A JPS6463518 A JP S6463518A JP 62221142 A JP62221142 A JP 62221142A JP 22114287 A JP22114287 A JP 22114287A JP S6463518 A JPS6463518 A JP S6463518A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- antiarrhythmic agent
- phenylalkyl
- bond
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE:To obtain an antiarrhythmic agent suppressing irritation formation abnormality occurring during ischemia almost without influencing contractive force of cardiac muscle, containing a specific carbostyril derivative. CONSTITUTION:An antiarrhythmic agent containing a compound shown by the formula [R<1> is H, alkyl, alkenyl, alkynyl or phenylalkyl; R<2> and R<3> are H, alkyl, cycloalkyl, pyridyl or phenylalkyl or R<2> and R<3> together with bonded N form 5--9-membered saturated or unsaturated heterocyclic ring (further may contain N, O or S); A is alkylene; R<4> is H, alkyl, phenyl, alkoxy or halogen; bond of carbostyril skeleton at 3-position and 4-position is single bond or double bond] or a salt thereof such as 3-(1-6-butylamino-1-phenylmethyl)-8- methylcarbostyril as an active ingredient. A dose of the compound is preferably 0.1-10mg/kg weight/day.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62221142A JPS6463518A (en) | 1987-09-02 | 1987-09-02 | Antiarrhythmic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62221142A JPS6463518A (en) | 1987-09-02 | 1987-09-02 | Antiarrhythmic agent |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63230457A Division JPH01125369A (en) | 1988-09-14 | 1988-09-14 | Carbostyril derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6463518A true JPS6463518A (en) | 1989-03-09 |
Family
ID=16762124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62221142A Pending JPS6463518A (en) | 1987-09-02 | 1987-09-02 | Antiarrhythmic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6463518A (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0382687A2 (en) * | 1989-02-06 | 1990-08-16 | BOEHRINGER INGELHEIM ITALIA S.p.A. | Benzofused-N-containing heterocycle derivatives |
US5607946A (en) * | 1993-03-05 | 1997-03-04 | Merck Sharp & Dohme Ltd. | Quinolone derivatives as dopamine D4 ligands |
WO2001053288A1 (en) * | 2000-01-20 | 2001-07-26 | Eisai Co., Ltd. | Novel piperidine compounds and drugs containing the same |
USRE37395E1 (en) | 1987-09-10 | 2001-10-02 | Saint-Gobain Glass France | Method of centering windshield glazings |
WO2007117778A2 (en) * | 2006-02-24 | 2007-10-18 | Kalypsys, Inc. | Quinolones useful as inducible nitric oxide synthase inhibitors |
JP2009502869A (en) * | 2005-07-28 | 2009-01-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Antibacterial quinoline derivatives |
US20100210836A1 (en) * | 2009-02-13 | 2010-08-19 | University Of Southern California | Small molecule inhibitors of lymphoid tyrosine phosphatase |
US7939545B2 (en) * | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
US8354429B2 (en) | 2007-11-16 | 2013-01-15 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
US8377960B2 (en) | 2007-11-15 | 2013-02-19 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
WO2022056068A1 (en) * | 2020-09-09 | 2022-03-17 | The Regents Of The University Ofcalifornia | Small molecule inhibitors of enpp1 |
-
1987
- 1987-09-02 JP JP62221142A patent/JPS6463518A/en active Pending
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE37395E1 (en) | 1987-09-10 | 2001-10-02 | Saint-Gobain Glass France | Method of centering windshield glazings |
EP0382687A2 (en) * | 1989-02-06 | 1990-08-16 | BOEHRINGER INGELHEIM ITALIA S.p.A. | Benzofused-N-containing heterocycle derivatives |
US5607946A (en) * | 1993-03-05 | 1997-03-04 | Merck Sharp & Dohme Ltd. | Quinolone derivatives as dopamine D4 ligands |
WO2001053288A1 (en) * | 2000-01-20 | 2001-07-26 | Eisai Co., Ltd. | Novel piperidine compounds and drugs containing the same |
US6784192B2 (en) | 2000-01-20 | 2004-08-31 | Eisai Co., Ltd. | Piperidine compound and pharmaceutical composition thereof |
JP2009502869A (en) * | 2005-07-28 | 2009-01-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Antibacterial quinoline derivatives |
EP1912948B1 (en) * | 2005-07-28 | 2015-09-09 | Janssen Pharmaceutica NV | Antibacterial quinoline derivatives |
US7915292B2 (en) * | 2005-07-28 | 2011-03-29 | Janssen Pharmaceutica Nv | Antibacterial quinoline derivatives |
WO2007117778A2 (en) * | 2006-02-24 | 2007-10-18 | Kalypsys, Inc. | Quinolones useful as inducible nitric oxide synthase inhibitors |
WO2007117778A3 (en) * | 2006-02-24 | 2008-02-07 | Kalypsys Inc | Quinolones useful as inducible nitric oxide synthase inhibitors |
US7939545B2 (en) * | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
US8377960B2 (en) | 2007-11-15 | 2013-02-19 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
US8354429B2 (en) | 2007-11-16 | 2013-01-15 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
US8710230B2 (en) | 2007-11-16 | 2014-04-29 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
US20100210836A1 (en) * | 2009-02-13 | 2010-08-19 | University Of Southern California | Small molecule inhibitors of lymphoid tyrosine phosphatase |
WO2022056068A1 (en) * | 2020-09-09 | 2022-03-17 | The Regents Of The University Ofcalifornia | Small molecule inhibitors of enpp1 |
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