JPS6456A - Cyclopentane derivative and producing thereof - Google Patents

Cyclopentane derivative and producing thereof

Info

Publication number
JPS6456A
JPS6456A JP62259646A JP25964687A JPS6456A JP S6456 A JPS6456 A JP S6456A JP 62259646 A JP62259646 A JP 62259646A JP 25964687 A JP25964687 A JP 25964687A JP S6456 A JPS6456 A JP S6456A
Authority
JP
Japan
Prior art keywords
amino
formula
expressed
azide
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62259646A
Other languages
Japanese (ja)
Other versions
JPH0798778B2 (en
JPH0156A (en
Inventor
Yoshitomi Morisawa
Arata Yasuda
Toshiaki Nakayama
Keiichi Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP62259646A priority Critical patent/JPH0798778B2/en
Priority to EP88101269A priority patent/EP0277599A3/en
Publication of JPS6456A publication Critical patent/JPS6456A/en
Publication of JPH0156A publication Critical patent/JPH0156A/en
Publication of JPH0798778B2 publication Critical patent/JPH0798778B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

NEW MATERIAL:A 3-fluoro-2-hydroxy-1-substituted-4-hydroxymethylcyclopentane derivative expressed by formula I (B is residue of nucleic acid bases, azide, amino or amino having protecting group; R1 and R2 are H or protecting group).
EXAMPLE: 4β-Acetamido-3β-hyroxy-2α-fluoro-1β-cyclopentane methyl acetate.
USE: Fluorine-containing nucleosides having high chemical stability and synthetic intermediate therefor.
PREPARATION: An epoxide expressed by formula II [R3 is azide or (protected) amino] is fluorinated with a fluorinating agent to introduce fluorine atom. into the 3-position and, as necessary, deprotection, formation of skeleton of nucleic acid bases, etc., are carried out to afford the aimed compound expressed by formula I.
COPYRIGHT: (C)1989,JPO&Japio
JP62259646A 1987-01-30 1987-10-16 Cyclopentane derivative Expired - Lifetime JPH0798778B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP62259646A JPH0798778B2 (en) 1987-02-10 1987-10-16 Cyclopentane derivative
EP88101269A EP0277599A3 (en) 1987-01-30 1988-01-28 Fluorine containing cyclopentane derivatives and processes for their production

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP62-27290 1987-02-10
JP2729087 1987-02-10
JP62259646A JPH0798778B2 (en) 1987-02-10 1987-10-16 Cyclopentane derivative

Publications (3)

Publication Number Publication Date
JPS6456A true JPS6456A (en) 1989-01-05
JPH0156A JPH0156A (en) 1989-01-05
JPH0798778B2 JPH0798778B2 (en) 1995-10-25

Family

ID=26365195

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62259646A Expired - Lifetime JPH0798778B2 (en) 1987-01-30 1987-10-16 Cyclopentane derivative

Country Status (1)

Country Link
JP (1) JPH0798778B2 (en)

Also Published As

Publication number Publication date
JPH0798778B2 (en) 1995-10-25

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