JPS6431720A - Antihyperlipemic agent consisting of pyrimido(2,1-b)benzothiazole derivative - Google Patents

Antihyperlipemic agent consisting of pyrimido(2,1-b)benzothiazole derivative

Info

Publication number
JPS6431720A
JPS6431720A JP62187383A JP18738387A JPS6431720A JP S6431720 A JPS6431720 A JP S6431720A JP 62187383 A JP62187383 A JP 62187383A JP 18738387 A JP18738387 A JP 18738387A JP S6431720 A JPS6431720 A JP S6431720A
Authority
JP
Japan
Prior art keywords
pyrimido
agent
antihyperlipemic
benzothiazole derivative
agent consisting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62187383A
Other languages
Japanese (ja)
Inventor
Jiro Horiuchi
Tatsushi Niwa
Shinya Katagiri
Yoshiyasu Shidori
Tetsuzo Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
Mect Corp
Original Assignee
KANTO ISHI PHARMA CO Ltd
Mect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANTO ISHI PHARMA CO Ltd, Mect Corp filed Critical KANTO ISHI PHARMA CO Ltd
Priority to JP62187383A priority Critical patent/JPS6431720A/en
Priority to CA000545326A priority patent/CA1297100C/en
Priority to NZ221579A priority patent/NZ221579A/en
Priority to AU77431/87A priority patent/AU591419B2/en
Priority to AT87112499T priority patent/ATE66812T1/en
Priority to EP87112499A priority patent/EP0261439B1/en
Priority to DE8787112499T priority patent/DE3772687D1/en
Priority to CN87105862A priority patent/CN1016668B/en
Priority to DK453387A priority patent/DK453387A/en
Priority to KR1019870009472A priority patent/KR900000293B1/en
Publication of JPS6431720A publication Critical patent/JPS6431720A/en
Pending legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE:To obtain antihyperlipemic agent containing a pyrimido[2,1- b]benzothiazole derivative as an active ingredient. CONSTITUTION:An antihyperlipemic agent obtained by containing an effective amount of a compound expressed by formula I (Ph is phenyl; Me is methyl) together with a carrier, such as stabilizer, preservative, buffer agent, isotonizing agent, etc. The above-mentioned compound has effects on reduction of low- density lipoprotein and ultralow-density lipoprotein, damaging vascular endothelium and causing arteriosclerosis in lipoproteins and the dose thereof is preferably within the range of 0.05-0.5g per day. The compound expressed by formula I is obtained by reaction shown in the reaction formulas.
JP62187383A 1986-08-28 1987-07-27 Antihyperlipemic agent consisting of pyrimido(2,1-b)benzothiazole derivative Pending JPS6431720A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP62187383A JPS6431720A (en) 1987-07-27 1987-07-27 Antihyperlipemic agent consisting of pyrimido(2,1-b)benzothiazole derivative
CA000545326A CA1297100C (en) 1986-08-28 1987-08-25 Medicament for curing arteriosclerosis, comprising pyrimido [2,1-b]-benxothiazole derivative
NZ221579A NZ221579A (en) 1986-08-28 1987-08-26 Medicament containing pyrimido (2,1,-b) benzothiazole for treating arteriosclerosis
AU77431/87A AU591419B2 (en) 1986-08-28 1987-08-26 Medicament for curing arteriosclerosis comprising pyrimido (2,1-b) benzothiazole derivative
AT87112499T ATE66812T1 (en) 1986-08-28 1987-08-27 MEDICATION FOR CURING ARTERIOSCLEROSIS CONTAINING A PYRIMIDO(2,1-B)BENZOTHIAZOLE DERIVATIVE.
EP87112499A EP0261439B1 (en) 1986-08-28 1987-08-27 Medicament for curing arteriosclerosis, comprising pyrimido (2,1-b) benzothiazole derivative
DE8787112499T DE3772687D1 (en) 1986-08-28 1987-08-27 MEDICINES FOR HEALING ARTERIOSCLEROSIS CONTAINING A PYRIMIDO (2,1-B) BENZOTHIAZOLE DERIVATIVE.
CN87105862A CN1016668B (en) 1986-08-28 1987-08-28 Method for preparation of medicines composition for treating arteriosclerosis
DK453387A DK453387A (en) 1986-08-28 1987-08-28 AGENT FOR THE TREATMENT OF ARTERYOS SCLEROSIS AND PREVENTION OF Platelet coagulation
KR1019870009472A KR900000293B1 (en) 1986-08-28 1987-08-28 Medicament for curing arteriosclerosis,comprising pyrimido(2.1-b)benzothiazole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62187383A JPS6431720A (en) 1987-07-27 1987-07-27 Antihyperlipemic agent consisting of pyrimido(2,1-b)benzothiazole derivative

Publications (1)

Publication Number Publication Date
JPS6431720A true JPS6431720A (en) 1989-02-02

Family

ID=16205052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62187383A Pending JPS6431720A (en) 1986-08-28 1987-07-27 Antihyperlipemic agent consisting of pyrimido(2,1-b)benzothiazole derivative

Country Status (1)

Country Link
JP (1) JPS6431720A (en)

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