JPS6429393A - Nucleoside analog - Google Patents

Nucleoside analog

Info

Publication number
JPS6429393A
JPS6429393A JP62183659A JP18365987A JPS6429393A JP S6429393 A JPS6429393 A JP S6429393A JP 62183659 A JP62183659 A JP 62183659A JP 18365987 A JP18365987 A JP 18365987A JP S6429393 A JPS6429393 A JP S6429393A
Authority
JP
Japan
Prior art keywords
derivative
reacted
acetylamine
deoxy
alkoxycarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62183659A
Other languages
Japanese (ja)
Inventor
Yoshitomi Morisawa
Toshiaki Nakayama
Arata Yasuda
Keiichi Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP62183659A priority Critical patent/JPS6429393A/en
Publication of JPS6429393A publication Critical patent/JPS6429393A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

NEW MATERIAL:A compound expressed by the formula (B is -CH= or -N=; X and Y are cyano, amino, alkoxycarbonyl, etc.; Z is H or alkoxycarbonyl; R<1> and R<2> are H or protecting groups of hydroxyl groups). EXAMPLE:4, 5-Diethoxycarbonyl-3-(3-deoxy-3-fluoro-2, 5-O-dibenzoyl-beta-D-ribofura nosyl)-1H-pyrazole. USE:An antitumor and antiviral agents. PREPARATION:For example, methyl 2,5-di-O-benzoyl-3-deoxy-3-fluoro-beta-D- ribofuranoside is dissolved in acetic acid and acetic anhydride, treated with hydrogen bromide and brominated. Mercuric cyanide is then added to provide a cyano derivative, which is subsequently reduced and reacted with acetic anhy dride to afford an acetylamine derivative. The resultant acetylamine derivative is then reacted with benzyl bromide to provide a dibenzyl derivative, which is subsequently treated with nitrogen dioxide in the presence of acetic acid, diazotized and reacted with diethyl acetylenedicarboxylate to afford the aimed compound expressed by the formula.
JP62183659A 1987-07-24 1987-07-24 Nucleoside analog Pending JPS6429393A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62183659A JPS6429393A (en) 1987-07-24 1987-07-24 Nucleoside analog

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62183659A JPS6429393A (en) 1987-07-24 1987-07-24 Nucleoside analog

Publications (1)

Publication Number Publication Date
JPS6429393A true JPS6429393A (en) 1989-01-31

Family

ID=16139681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62183659A Pending JPS6429393A (en) 1987-07-24 1987-07-24 Nucleoside analog

Country Status (1)

Country Link
JP (1) JPS6429393A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
US5438131A (en) * 1992-09-16 1995-08-01 Bergstrom; Donald E. 3-nitropyrrole nucleoside

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
US5438131A (en) * 1992-09-16 1995-08-01 Bergstrom; Donald E. 3-nitropyrrole nucleoside

Similar Documents

Publication Publication Date Title
AU8551091A (en) Process for the production of carboxylic acid anhydrides
JPS5227721A (en) Process for preparation of substituted phosphonic acid derivatives
JPS6429393A (en) Nucleoside analog
JPS57179147A (en) Amidine derivative
AU1505892A (en) Process for preparing hindered amine light stabilizers
GR3006438T3 (en)
JPS57108072A (en) Preparation of n-acylcarnosine
JPS55139336A (en) Preparation of polycarboxylic acid and its ester
DK0493064T3 (en) Deacetylcolchicine derivatives
JPS57192340A (en) Isoprenylamine derivative
JPS55149299A (en) N6-substituted cordicepin derivative and its preparation
JPS6483089A (en) Production of vinylsilanes
JPS6419087A (en) Production of 1,3,4-tri-o-acyl-2-deoxy-beta-d-erythro-pentapyranose
JPS5643287A (en) Preparation of cephamycin derivative
JPS5256193A (en) Process for copolyesterpolyol
JPS5714598A (en) 5-substituted-1-beta-d-arabinofuranosyluracil derivative and its preparation
JPS5210207A (en) Process for preparation of high purity pulenol
JPS55102548A (en) Nitrosamine derivative
JPS5247893A (en) Process for preparing hydroscopic polyamides
JPS6445392A (en) Production of estradiol derivative
JPS51133296A (en) Processes for preparing 7-acylamino- 3-hydroxymethyl-2-cephem-4-carbox ylic acid derivatives
JPS55115899A (en) 3,18-o-cyclotylosin derivative
AU680325B2 (en) Process for the carbonylation of an acetylenically unsaturated compound
JPS6431762A (en) Dihalogenoindole derivative
JPS55102559A (en) Production of 2-methoxy-5-sulfamoylbenzoic acid amide