JPS6427483A - Production of poly-beta-hydroxybutyric acid - Google Patents
Production of poly-beta-hydroxybutyric acidInfo
- Publication number
- JPS6427483A JPS6427483A JP62183260A JP18326087A JPS6427483A JP S6427483 A JPS6427483 A JP S6427483A JP 62183260 A JP62183260 A JP 62183260A JP 18326087 A JP18326087 A JP 18326087A JP S6427483 A JPS6427483 A JP S6427483A
- Authority
- JP
- Japan
- Prior art keywords
- beta
- hydroxybutyric acid
- poly
- methanol
- culture liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WHBMMWSBFZVSSR-UHFFFAOYSA-N 3-hydroxybutyric acid Chemical compound CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 title abstract 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 15
- 230000000813 microbial effect Effects 0.000 abstract 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000004748 cultured cell Anatomy 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE:To accumulate low-molecular weight poly-beta-hydroxybutyric acid, by using a microbial strain capable of assimilating methanol and accumulating poly-beta-hydroxybutyric acid in the microbial cell and culturing the strain in a medium containing methanol, ammonia, etc. CONSTITUTION:A microbial strain capable of assimilating methanol and accumulating poly-beta-hydroxybutyric acid in the microbial cell is cultured and proliferated in a medium at least containing methanol as a carbon source and ammonia and/or ammonium salt as a nitrogen source. The cultured cells are further cultured while controlling the methanol concentration in the culture liquid within 5-50g per 1l of the culture liquid to effect the production and accumulation of a low-molecular weight poly-beta-hydroxybutyric acid in the microbial cell and produce the objective poly-beta-hydroxybutyric acid. The culture temperature is preferably 29-31 deg.C and the dissolved oxygen concentration in the culture liquid is preferably controlled to about 1-7ppm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62183260A JPS6427483A (en) | 1987-07-24 | 1987-07-24 | Production of poly-beta-hydroxybutyric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62183260A JPS6427483A (en) | 1987-07-24 | 1987-07-24 | Production of poly-beta-hydroxybutyric acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6427483A true JPS6427483A (en) | 1989-01-30 |
| JPH0425798B2 JPH0425798B2 (en) | 1992-05-01 |
Family
ID=16132553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62183260A Granted JPS6427483A (en) | 1987-07-24 | 1987-07-24 | Production of poly-beta-hydroxybutyric acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6427483A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002017380A (en) * | 2000-07-06 | 2002-01-22 | Mitsubishi Gas Chem Co Inc | Method for producing poly-3-hydroxybutyric acid |
| WO2004033670A1 (en) * | 2002-10-10 | 2004-04-22 | Kaneka Corporation | Culture method of controlling the composition of copolymer polyester |
-
1987
- 1987-07-24 JP JP62183260A patent/JPS6427483A/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002017380A (en) * | 2000-07-06 | 2002-01-22 | Mitsubishi Gas Chem Co Inc | Method for producing poly-3-hydroxybutyric acid |
| WO2004033670A1 (en) * | 2002-10-10 | 2004-04-22 | Kaneka Corporation | Culture method of controlling the composition of copolymer polyester |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0425798B2 (en) | 1992-05-01 |
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