JPS6422895A - Nulceotides - Google Patents

Nulceotides

Info

Publication number
JPS6422895A
JPS6422895A JP17723287A JP17723287A JPS6422895A JP S6422895 A JPS6422895 A JP S6422895A JP 17723287 A JP17723287 A JP 17723287A JP 17723287 A JP17723287 A JP 17723287A JP S6422895 A JPS6422895 A JP S6422895A
Authority
JP
Japan
Prior art keywords
deoxy
formula
fluoroadenosine
methylene chloride
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17723287A
Other languages
Japanese (ja)
Inventor
Yoshitomi Morisawa
Toshiaki Nakayama
Arata Yasuda
Keiichi Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP17723287A priority Critical patent/JPS6422895A/en
Publication of JPS6422895A publication Critical patent/JPS6422895A/en
Pending legal-status Critical Current

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Abstract

NEW MATERIAL:Phosphoric acid esters of 3'-deoxy-3'-fluoronucleoside derivatives expressed by the formula (B is residue of nucleic acid bases). EXAMPLE:3'-Deoxy-3'-fluoroadenosine-5'-monophosphate. USE:A medicine, such as antitumor and antiviral agents. PREPARATION:For example, triazole is suspended in methylene chloride and o-chlorophenyl phosphorodichloridate which is a phosphorylating agent is added to the resultant suspension while cooling with ice and stirred. A solution of the compounds expressed by the formula, such as N<6>,2'-O-dibenzoyl-3'-deoxy-3'- fluoroadenosine, in pyridine-methylene chloride is added thereto and reacted to carry out phosphorylation of the compounds expressed by the formula.
JP17723287A 1987-07-17 1987-07-17 Nulceotides Pending JPS6422895A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17723287A JPS6422895A (en) 1987-07-17 1987-07-17 Nulceotides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17723287A JPS6422895A (en) 1987-07-17 1987-07-17 Nulceotides

Publications (1)

Publication Number Publication Date
JPS6422895A true JPS6422895A (en) 1989-01-25

Family

ID=16027462

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17723287A Pending JPS6422895A (en) 1987-07-17 1987-07-17 Nulceotides

Country Status (1)

Country Link
JP (1) JPS6422895A (en)

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