JPS6422823A - Antiulcer agent - Google Patents
Antiulcer agentInfo
- Publication number
- JPS6422823A JPS6422823A JP17723387A JP17723387A JPS6422823A JP S6422823 A JPS6422823 A JP S6422823A JP 17723387 A JP17723387 A JP 17723387A JP 17723387 A JP17723387 A JP 17723387A JP S6422823 A JPS6422823 A JP S6422823A
- Authority
- JP
- Japan
- Prior art keywords
- deoxy
- nucleotide
- derivative
- fluoronucleoxide
- antiulcer agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE:To obtain an antiulcer agent containing novel nucleotides consisting of phosphoric acid ester of 3'-deoxy-3'-fluoronucleoxide derivative as active ingredients. CONSTITUTION:Nucleotides consisting of phosphoric acid ester of 3'-deoxy-3''- fluoronucleoxide derivative expressed by the formula (B is residue of nucleic acid bases) or salt thereof are blended as active ingredients to provide the aimed antiulcer agent. The compound expressed by the formula is obtained using furanosyl halide or 1-0-acylated sugar as a raw material through fluorination process according to a conventional nucleotide synthetic method. Phosphorylation method for synthesizing a nucleotide from a nucleoxide is carried out after properly protecting function group thereof according to a conventional method by using a phosphorylating agent such as 0- chlorophenylphosphorodichlorodate. The nucleotide derivative includes e.g. 3'- deoxy-3''-fluoroadenosine-5'-cyclooctanylphosphate.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17723387A JPS6422823A (en) | 1987-07-17 | 1987-07-17 | Antiulcer agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17723387A JPS6422823A (en) | 1987-07-17 | 1987-07-17 | Antiulcer agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6422823A true JPS6422823A (en) | 1989-01-25 |
Family
ID=16027480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17723387A Pending JPS6422823A (en) | 1987-07-17 | 1987-07-17 | Antiulcer agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6422823A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10206370A1 (en) * | 2002-02-15 | 2003-09-04 | Infineon Technologies Ag | Method and device for phase detection |
JP2015500851A (en) * | 2011-12-20 | 2015-01-08 | リボサイエンス・エルエルシー | 4'-azido, 3'-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication |
JP2016519146A (en) * | 2013-05-16 | 2016-06-30 | リボサイエンス・エルエルシー | 4'-azido, 3'-deoxy-3'-fluoro substituted nucleoside derivatives |
-
1987
- 1987-07-17 JP JP17723387A patent/JPS6422823A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10206370A1 (en) * | 2002-02-15 | 2003-09-04 | Infineon Technologies Ag | Method and device for phase detection |
DE10206370B4 (en) * | 2002-02-15 | 2005-08-25 | Infineon Technologies Ag | Method and device for phase detection |
JP2015500851A (en) * | 2011-12-20 | 2015-01-08 | リボサイエンス・エルエルシー | 4'-azido, 3'-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication |
JP2016519146A (en) * | 2013-05-16 | 2016-06-30 | リボサイエンス・エルエルシー | 4'-azido, 3'-deoxy-3'-fluoro substituted nucleoside derivatives |
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