JPS6417653A - Laminate type hybrid artificial liver apparatus - Google Patents

Laminate type hybrid artificial liver apparatus

Info

Publication number
JPS6417653A
JPS6417653A JP62174315A JP17431587A JPS6417653A JP S6417653 A JPS6417653 A JP S6417653A JP 62174315 A JP62174315 A JP 62174315A JP 17431587 A JP17431587 A JP 17431587A JP S6417653 A JPS6417653 A JP S6417653A
Authority
JP
Japan
Prior art keywords
hepatocyte
plasma
receiving part
sheets
liver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62174315A
Other languages
Japanese (ja)
Inventor
Toshiichi Nakamura
Etsuro Hashimura
Akihiko Funatsu
Takashi Komai
Toshihiko Tsuburaya
Fumiaki Kumagai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP62174315A priority Critical patent/JPS6417653A/en
Publication of JPS6417653A publication Critical patent/JPS6417653A/en
Pending legal-status Critical Current

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Abstract

PURPOSE:To sufficiently act for the original function of the liver of a living body for a long time, by mounting a receiving part receiving unilaminar cultured hepatocyte sheets each having a hepatocyte adhered on the surface thereof and keeping liver function in a laminated state and a plasma inflow/outflow part for allowing separated plasma to flow-in and flow-out into and from the housing part. CONSTITUTION:About 200 hepatocyte sheets 2 are accommodated in a receiving part 4 in a laminated state in the manner that the surfaces each having no hepatocyte adhered thereon are brought into contact with each other. A plasma inflow part 11 is mounted to the upper end part of the receiving part 4 and a plasma diffusion chamber 21 is provided between the plasma inflow part 11 and the receiving part 4 so as to allow the plasma passing through a piercing port 13 to uniformly flow-in over the total laminated area of the hepatocyte sheets 2. Two upper and lower reticulated filters 22 are arranged to the lower end of the diffusion chamber in an overlapped state and the plasma flowing in the receiving part 4 through said filters is brought into contact with a hepatocyte while flowing along the hepatocyte adhering surfaces of the hepatocyte sheets 2 and the sufficient treatment equal to the treatment in the liver of a living body is performed.
JP62174315A 1987-07-13 1987-07-13 Laminate type hybrid artificial liver apparatus Pending JPS6417653A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62174315A JPS6417653A (en) 1987-07-13 1987-07-13 Laminate type hybrid artificial liver apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62174315A JPS6417653A (en) 1987-07-13 1987-07-13 Laminate type hybrid artificial liver apparatus

Publications (1)

Publication Number Publication Date
JPS6417653A true JPS6417653A (en) 1989-01-20

Family

ID=15976504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62174315A Pending JPS6417653A (en) 1987-07-13 1987-07-13 Laminate type hybrid artificial liver apparatus

Country Status (1)

Country Link
JP (1) JPS6417653A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999012589A1 (en) * 1997-09-09 1999-03-18 Foryou Corporation Artificial organ

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999012589A1 (en) * 1997-09-09 1999-03-18 Foryou Corporation Artificial organ

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