JPS6417649A - Preparation of antithrombogenic cellulose - Google Patents
Preparation of antithrombogenic celluloseInfo
- Publication number
- JPS6417649A JPS6417649A JP62173892A JP17389287A JPS6417649A JP S6417649 A JPS6417649 A JP S6417649A JP 62173892 A JP62173892 A JP 62173892A JP 17389287 A JP17389287 A JP 17389287A JP S6417649 A JPS6417649 A JP S6417649A
- Authority
- JP
- Japan
- Prior art keywords
- cellulose
- heparin
- water
- org
- base material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE:To impart an antithrombogenic property stable for a long period of time, by activating base material composed of regenerated cellulose or a cellulose derivative with alkali and subsequently bringing the same into contact with heparin dissolved in a water-org. solvent mixture. CONSTITUTION:Alkali activation is performed by immersing a base material composed of regenerated cellulose or a cellulose in an sodium hydroxide or potassium hydroxide solution with a concn. of 1X10<-6>-50wt.% at 0-200 deg.C for 5sec-120min. A water-org. solvent mixture dissolving heparin is a water- tetrahydrofuran mixture and the concn. of heparin in this mixture is 0.01-20wt.% and the contact with heparin dissolved in the water-org. solvent mixture is performed at 0-125 deg.C for 1-2X10<4>min. By this method, cellulose is swollen on the surface region of the base material as alkali cellulose and, further, the hydrogen bond of cellulose is cut to enhance the mobility of a molecule and said cellulose becomes a state easy to take-in heparin. Therefore, antithrombogenic cellulose shows heparin gradual release property even in blood.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62173892A JP2644756B2 (en) | 1987-07-14 | 1987-07-14 | Method for producing anticoagulable cellulose |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62173892A JP2644756B2 (en) | 1987-07-14 | 1987-07-14 | Method for producing anticoagulable cellulose |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6417649A true JPS6417649A (en) | 1989-01-20 |
JP2644756B2 JP2644756B2 (en) | 1997-08-25 |
Family
ID=15969035
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62173892A Expired - Fee Related JP2644756B2 (en) | 1987-07-14 | 1987-07-14 | Method for producing anticoagulable cellulose |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2644756B2 (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006526673A (en) * | 2003-03-21 | 2006-11-24 | ザ ユニバーシティ オブ アラバマ | Cellulose matrix encapsulation and method |
US7888412B2 (en) | 2004-03-26 | 2011-02-15 | Board Of Trustees Of The University Of Alabama | Polymer dissolution and blend formation in ionic liquids |
US8668807B2 (en) | 2008-02-19 | 2014-03-11 | Board Of Trustees Of The University Of Alabama | Ionic liquid systems for the processing of biomass, their components and/or derivatives, and mixtures thereof |
US8784691B2 (en) | 2009-07-24 | 2014-07-22 | Board Of Trustees Of The University Of Alabama | Conductive composites prepared using ionic liquids |
US8883193B2 (en) | 2005-06-29 | 2014-11-11 | The University Of Alabama | Cellulosic biocomposites as molecular scaffolds for nano-architectures |
US9096743B2 (en) | 2009-06-01 | 2015-08-04 | The Board Of Trustees Of The University Of Alabama | Process for forming films, fibers, and beads from chitinous biomass |
US9278134B2 (en) | 2008-12-29 | 2016-03-08 | The Board Of Trustees Of The University Of Alabama | Dual functioning ionic liquids and salts thereof |
US9394375B2 (en) | 2011-03-25 | 2016-07-19 | Board Of Trustees Of The University Of Alabama | Compositions containing recyclable ionic liquids for use in biomass processing |
US10100131B2 (en) | 2014-08-27 | 2018-10-16 | The Board Of Trustees Of The University Of Alabama | Chemical pulping of chitinous biomass for chitin |
US10927191B2 (en) | 2017-01-06 | 2021-02-23 | The Board Of Trustees Of The University Of Alabama | Coagulation of chitin from ionic liquid solutions using kosmotropic salts |
US10941258B2 (en) | 2017-03-24 | 2021-03-09 | The Board Of Trustees Of The University Of Alabama | Metal particle-chitin composite materials and methods of making thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53120883A (en) * | 1977-03-29 | 1978-10-21 | Unitika Ltd | Antiithrombus cellulose material |
JPS59225064A (en) * | 1983-06-03 | 1984-12-18 | ユニチカ株式会社 | Carrier for immobilizing physiologically active substance |
JPH0334739A (en) * | 1989-06-30 | 1991-02-14 | Nippon Telegr & Teleph Corp <Ntt> | Packet communication system |
-
1987
- 1987-07-14 JP JP62173892A patent/JP2644756B2/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53120883A (en) * | 1977-03-29 | 1978-10-21 | Unitika Ltd | Antiithrombus cellulose material |
JPS59225064A (en) * | 1983-06-03 | 1984-12-18 | ユニチカ株式会社 | Carrier for immobilizing physiologically active substance |
JPH0334739A (en) * | 1989-06-30 | 1991-02-14 | Nippon Telegr & Teleph Corp <Ntt> | Packet communication system |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006526673A (en) * | 2003-03-21 | 2006-11-24 | ザ ユニバーシティ オブ アラバマ | Cellulose matrix encapsulation and method |
EP1648692A4 (en) * | 2003-03-21 | 2009-06-10 | Univ Alabama | Cellulose matrix encapsulation and method |
JP2011125864A (en) * | 2003-03-21 | 2011-06-30 | Univ Of Alabama | Cellulose matrix encapsulation and method |
US7888412B2 (en) | 2004-03-26 | 2011-02-15 | Board Of Trustees Of The University Of Alabama | Polymer dissolution and blend formation in ionic liquids |
US8883193B2 (en) | 2005-06-29 | 2014-11-11 | The University Of Alabama | Cellulosic biocomposites as molecular scaffolds for nano-architectures |
US8668807B2 (en) | 2008-02-19 | 2014-03-11 | Board Of Trustees Of The University Of Alabama | Ionic liquid systems for the processing of biomass, their components and/or derivatives, and mixtures thereof |
US9278134B2 (en) | 2008-12-29 | 2016-03-08 | The Board Of Trustees Of The University Of Alabama | Dual functioning ionic liquids and salts thereof |
US9096743B2 (en) | 2009-06-01 | 2015-08-04 | The Board Of Trustees Of The University Of Alabama | Process for forming films, fibers, and beads from chitinous biomass |
US8784691B2 (en) | 2009-07-24 | 2014-07-22 | Board Of Trustees Of The University Of Alabama | Conductive composites prepared using ionic liquids |
US9394375B2 (en) | 2011-03-25 | 2016-07-19 | Board Of Trustees Of The University Of Alabama | Compositions containing recyclable ionic liquids for use in biomass processing |
US10100131B2 (en) | 2014-08-27 | 2018-10-16 | The Board Of Trustees Of The University Of Alabama | Chemical pulping of chitinous biomass for chitin |
US10927191B2 (en) | 2017-01-06 | 2021-02-23 | The Board Of Trustees Of The University Of Alabama | Coagulation of chitin from ionic liquid solutions using kosmotropic salts |
US10941258B2 (en) | 2017-03-24 | 2021-03-09 | The Board Of Trustees Of The University Of Alabama | Metal particle-chitin composite materials and methods of making thereof |
Also Published As
Publication number | Publication date |
---|---|
JP2644756B2 (en) | 1997-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS6417649A (en) | Preparation of antithrombogenic cellulose | |
ES2054613T3 (en) | A METHOD FOR PREPARING A MAINTENANCE RELEASE FORMULATION. | |
UA5934A1 (en) | Method for producing mucopolysaccharides | |
GB1524431A (en) | Production of long acting insulin preparations | |
DE3674739D1 (en) | METHOD FOR THE PRODUCTION OF (2,2) -PARACYCLOPHANE AND ITS COMBINED BLOCKS. | |
ES2014451B3 (en) | PROCEDURE FOR OBTAINING (2,2) -PARACICLOPHAN AND DERIVATIVES. | |
FI890772A (en) | bleaching process | |
IT1282994B1 (en) | DERIVATIVES OF THE POLYSACCHARIDE K5 HAVING HIGH ANTI-COAGULANT ACTIVITY | |
ATE55102T1 (en) | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLIODIDE. | |
NO903208D0 (en) | PROCEDURE FOR THE PREPARATION OF HALOGENAMINOAROMATIC DERIVATIVES. | |
JPS52152877A (en) | Membrane of ethylene-vinyl alcohol copolymer having excellent permeability and its production method | |
JPS645460A (en) | Production of delaying gelatinous material | |
NO904119L (en) | THROMBOLYTIC MATERIALS CONTAINING Tissue Type PLASMINOGEN ACTIVATOR OR DERIVATIVE THEREOF. | |
JPS5618606B2 (en) | ||
KR890002301A (en) | Manufacturing method of closed cell foam with high compressive strength | |
ATE2895T1 (en) | PROCESS FOR PRODUCTION OF 4-HYDROXY-CARBAZOLE. | |
SU1630288A1 (en) | METHOD FOR MAKING A COMPOSITION FOR A MATERIAL WITH VARIABLE LIGHTING | |
MY104925A (en) | Process for the preparation of sulfated alkanol oxethylates or alkylphenol oxethylates havinng a lowered content of 1, 4-dioxane | |
JPS52217A (en) | Process for removal formaldehyde in aqueous solution | |
JPS5432597A (en) | Purification of high molecular weight alkylene oxide polymer | |
JPS5270120A (en) | Production of raw material fibers for manufacturing carbon fibers | |
GB2012263A (en) | Aldehyde adducts | |
JPS6414201A (en) | Production of polyoxyethylenated chitin | |
GB1481949A (en) | Process for preparing hexafluoropropanone-2 | |
JPS54131658A (en) | Method for increasing moisture absorption of polymethyl- l-glutamate |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |