JPS6377806A - Denture stabilizer - Google Patents
Denture stabilizerInfo
- Publication number
- JPS6377806A JPS6377806A JP61220217A JP22021786A JPS6377806A JP S6377806 A JPS6377806 A JP S6377806A JP 61220217 A JP61220217 A JP 61220217A JP 22021786 A JP22021786 A JP 22021786A JP S6377806 A JPS6377806 A JP S6377806A
- Authority
- JP
- Japan
- Prior art keywords
- denture
- sodium polyacrylate
- soybean
- soybean lecithin
- stabilizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003381 stabilizer Substances 0.000 title claims abstract description 19
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims abstract description 21
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims abstract description 21
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims abstract description 14
- 229940083466 soybean lecithin Drugs 0.000 claims abstract description 14
- 239000003549 soybean oil Substances 0.000 claims abstract description 11
- 235000012424 soybean oil Nutrition 0.000 claims abstract description 11
- 238000004898 kneading Methods 0.000 claims abstract description 6
- 239000000853 adhesive Substances 0.000 claims description 19
- 230000001070 adhesive effect Effects 0.000 claims description 19
- 239000008157 edible vegetable oil Substances 0.000 claims 2
- 239000002674 ointment Substances 0.000 abstract description 13
- 239000003921 oil Substances 0.000 abstract description 7
- 235000019198 oils Nutrition 0.000 abstract description 7
- 239000003925 fat Substances 0.000 abstract description 6
- 235000013305 food Nutrition 0.000 abstract description 5
- 230000009967 tasteless effect Effects 0.000 abstract description 3
- 238000000926 separation method Methods 0.000 abstract description 2
- 235000011837 pasties Nutrition 0.000 abstract 3
- 239000000428 dust Substances 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 description 16
- 239000000047 product Substances 0.000 description 11
- 239000000203 mixture Substances 0.000 description 6
- 210000004400 mucous membrane Anatomy 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 3
- 244000068988 Glycine max Species 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 235000010445 lecithin Nutrition 0.000 description 3
- 239000000787 lecithin Substances 0.000 description 3
- 229940067606 lecithin Drugs 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- PZNPLUBHRSSFHT-RRHRGVEJSA-N 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCC PZNPLUBHRSSFHT-RRHRGVEJSA-N 0.000 description 2
- 239000000263 2,3-dihydroxypropyl (Z)-octadec-9-enoate Substances 0.000 description 2
- RZRNAYUHWVFMIP-GDCKJWNLSA-N 3-oleoyl-sn-glycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](O)CO RZRNAYUHWVFMIP-GDCKJWNLSA-N 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- -1 IJum Substances 0.000 description 2
- 235000019483 Peanut oil Nutrition 0.000 description 2
- 235000013871 bee wax Nutrition 0.000 description 2
- 239000012166 beeswax Substances 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000834 fixative Substances 0.000 description 2
- 235000013373 food additive Nutrition 0.000 description 2
- 239000002778 food additive Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 150000002334 glycols Chemical class 0.000 description 2
- 229910052740 iodine Inorganic materials 0.000 description 2
- 239000011630 iodine Substances 0.000 description 2
- 239000002075 main ingredient Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- RZRNAYUHWVFMIP-UHFFFAOYSA-N monoelaidin Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-UHFFFAOYSA-N 0.000 description 2
- 229940042880 natural phospholipid Drugs 0.000 description 2
- 239000003883 ointment base Substances 0.000 description 2
- 210000003254 palate Anatomy 0.000 description 2
- 239000000312 peanut oil Substances 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 239000008347 soybean phospholipid Substances 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- IHCCLXNEEPMSIO-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperidin-1-yl]-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical group C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C1CCN(CC1)CC(=O)N1CC2=C(CC1)NN=N2 IHCCLXNEEPMSIO-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 241000416162 Astragalus gummifer Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 240000005323 Hoya carnosa Species 0.000 description 1
- 235000010654 Melissa officinalis Nutrition 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 210000001557 animal structure Anatomy 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 235000013345 egg yolk Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Dental Preparations (AREA)
Abstract
Description
【発明の詳細な説明】
産業上の利用分野
本発明は義歯の固定に使用する軟膏剤即ち義歯安定剤に
関すると共にその製造に関連を有する。DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to ointments or denture adhesives for use in fixing dentures, and relates to the manufacture thereof.
従来の技術
義歯は一般に作製直後では口蓋、口底、及び顎堤弓(俗
称で「どて」と云う)の粘膜に密着し、食物の咀Ill
に際して離脱することなくその使用目的を果たすことが
できる。併しながら年月が経過するに従い口蓋、口底、
及び顎堤弓の自然変形が生ずるため、粘膜と義歯床の接
着面との間に隙間を生じ、食物の屑が入り込んで異物感
や疼痛を与える。このような義歯の不適合化は歯科医師
の調整加工により適合性が回復されるものであるが、多
くの場合患者は頻繁な調整加工を依頼することを怠るた
め、義歯の不適合性は漸進的に拡大し、義歯は常に離脱
し易くなり、言語にも支障を生ずるに至る。このような
不都合を救済するための処置として義歯安定剤が使用さ
れている。Conventional dentures generally adhere closely to the mucous membranes of the palate, floor of the mouth, and alveolar arch (commonly known as the "dote") immediately after they are made, and are difficult to swallow when chewing food.
The purpose of use can be fulfilled without detachment. However, as the years pass, the palate, floor of the mouth,
As natural deformation of the alveolar arch occurs, a gap is created between the mucous membrane and the adhesive surface of the denture base, allowing food particles to enter, causing a foreign body sensation and pain. Such ill-fitting dentures can be restored by adjustment by the dentist, but in many cases patients neglect to request frequent adjustments, so the ill-fitting dentures gradually become unfit. The dentures become enlarged, and the dentures tend to fall off constantly, leading to problems with speech. Denture adhesives are used as a treatment to relieve such inconveniences.
義歯安定剤にはアルギン酸す) IJウム、カルボキシ
メチルセルロース、メチルセルロース、ゼラチン、トラ
ガントガム、アラビアガムなどの粉末状糊剤を適宜混合
して義歯の粘膜接触部表面に散布する方式と、これらの
糊剤粉末を適当な軟膏基剤と練和して製した軟膏剤を義
歯の粘膜接触面に塗布する方式とがある。何れの場合に
も主成分である糊剤が唾液で湿潤した粘膜に粘着するこ
とにより義歯を固定するものである。(Alginic acid is used as a denture stabilizer) A method of mixing powdered adhesives such as IJum, carboxymethylcellulose, methylcellulose, gelatin, gum tragacanth, gum arabic, etc. and spraying it on the surface of the mucous membrane contact area of the denture, and powders of these adhesives. There is a method in which an ointment prepared by kneading the denture with a suitable ointment base is applied to the mucosal contact surface of the denture. In either case, the glue, which is the main ingredient, sticks to mucous membranes moistened with saliva, thereby fixing the denture in place.
前記の各種糊剤のほかに義歯固定剤の主成分としてポリ
アクリル酸ナトリウムが知られている(特開昭55−3
8143号)。このものの湿潤粘膜に対する粘着性は極
めて強く、かつ粘着状態の持続時間も長いので本物質を
粉末として使用する場合iは優れた義歯安定剤として役
立ち得る。In addition to the above-mentioned adhesives, sodium polyacrylate is known as a main component of denture fixatives (Japanese Unexamined Patent Publication No. 55-3
No. 8143). This substance has extremely strong adhesion to moist mucous membranes and remains sticky for a long time, so when this substance is used as a powder, it can serve as an excellent denture stabilizer.
発明が解決しようとする問題点
ところがポリアクリル酸ナトリウムはこれを軟膏状に製
剤して良質の軟膏状義歯安定剤を得ることは極めて困難
であった。即ちポリアクリル酸ナトリウムの粉末はこれ
を通常の軟膏基剤である植物油脂類、合成油脂であるグ
リセリンと脂肪酸とのモノ−ないしジ−エステル、或は
グリセリン、プロピレングリコールなどのグリコール類
等と練和した場合、一時的に均質な軟膏状態を呈するが
、時間の経過と共に基剤と粉末とが分離する傾向を生ず
る。このため練和した製剤を軟膏剤用チューブに充填し
ておくと粉体粒子が凝集してチューブからの押出しが困
難になり、長期間の保存に耐える均質な義歯安定剤を得
ることができない。例えばグリセリルモノオレエートの
如き常温でペースト状の合成油脂(日光ケミカル株式会
社製グリセリルモノオレエートM G O)を用いてこ
れをポリアクリル酸ナトリウム粉末と練和した場合にも
重量比の如何に係わらす練和後24時間で基剤と粉体と
の分離傾向が明かに認められ、粉体の凝集によりチュー
ブからの押出しが困難となる。このことはポリアクリル
酸ナトリウムがこの種の基剤との界面における親和性を
もたないことを示している。従って液状油脂に比較的融
点の高い蜜蝋を加えて調製したペースト状基剤を用いて
ポリアクリル酸ナトリウムと練和しても本質的な分離傾
向を長期にわたって防ぐことはできない。前記特開昭5
5−38143号公報実施例5にポリアクリル酸す)
IJウムを含む軟膏の製造方法が記載されているが、こ
の記載通りポリアクリル酸ナトリウム40部とアルギン
酸ナトリウム10部とよりなる50部の粉末状物質を4
0部の蜜蝋と10部のグリセリン脂肪酸エステルと共に
練和して常温で軟膏状である製品を得ることは不可能で
あった。即ちこの製品において蜜植が40部であり残部
60部の大部分50部(83%)が粉体であるのでこの
製品は割温下で固い螺状物質である。Problems to be Solved by the Invention However, it has been extremely difficult to formulate sodium polyacrylate into an ointment and obtain a high quality ointment-like denture stabilizer. That is, powder of sodium polyacrylate is prepared by mixing it with vegetable oils, which are common ointment bases, mono- or di-esters of glycerin and fatty acids, which are synthetic oils, or glycols, such as glycerin and propylene glycol. When mixed together, it temporarily takes on a homogeneous ointment state, but the base and powder tend to separate over time. For this reason, if a kneaded preparation is filled into an ointment tube, the powder particles will aggregate, making it difficult to extrude from the tube, making it impossible to obtain a homogeneous denture stabilizer that can be stored for a long period of time. For example, when using synthetic oils and fats that are paste-like at room temperature such as glyceryl monooleate (Glyceryl Monooleate M G O manufactured by Nikko Chemical Co., Ltd.) and kneading it with sodium polyacrylate powder, the weight ratio will vary. After 24 hours of kneading, there is a clear tendency for the base material to separate from the powder, and extrusion from the tube becomes difficult due to agglomeration of the powder. This indicates that sodium polyacrylate has no interfacial affinity with this type of base. Therefore, even if a paste base prepared by adding beeswax having a relatively high melting point to liquid oil and fat is kneaded with sodium polyacrylate, the essential tendency of separation cannot be prevented for a long period of time. Said Japanese Unexamined Patent Publication No. 5
5-38143 Publication Example 5 (polyacrylic acid)
A method for producing an ointment containing IJum is described, and as described, 50 parts of a powdery substance consisting of 40 parts of sodium polyacrylate and 10 parts of sodium alginate are mixed into 4
It was impossible to obtain a product that was ointment-like at room temperature by kneading with 0 parts of beeswax and 10 parts of glycerin fatty acid ester. That is, in this product, 40 parts are honey plants, and the remaining 60 parts, most of which are 50 parts (83%), are powder, so this product is a hard spiral material at a moderate temperature.
義歯安定剤として粉末の剤形と軟膏様の剤形とはそれぞ
れ特徴を持っており、何れが優れているかは一概に断定
できない。即ち一般に粉末状義歯安定剤は少イで強い義
歯固定力を示し、総義歯床ばかりでなく、部分義歯の固
定にもこれを用いることができるが、特に吸湿し易いポ
リアクリル酸す) IJウム又はゼラチン粉末を含む粉
末状固定剤については吸湿防止に十分注意することが必
要である。軟膏状の義歯安定剤はその粘着力が前者より
やや劣り、その使用は一般に総義歯のみに便利に用いら
れる。Powder-like and ointment-like forms of denture adhesive each have their own characteristics, and it is not possible to definitively determine which is better. That is, in general, powdered denture stabilizers exhibit strong denture fixing power with a small amount, and can be used not only for complete denture bases but also for fixing partial dentures. For powdered fixatives containing gelatin powder, sufficient care must be taken to prevent moisture absorption. Ointment-like denture adhesives have slightly lower adhesive strength than the former, and their use is generally convenient only for complete dentures.
粉末状及び軟膏状の義歯安定剤は義歯の構造、適合状態
及び装着者の好みにより使い分けられている。最近ポリ
アクリル酸ナトリウムを主成分とする粉末状義歯安定剤
は、その優れた粘着固定力により実用されるに至ってい
るが軟膏剤としては前記のような難点を有するため軟膏
状製品はまだ実用化されるに至っていない。本発明者は
ポリアクリル酸ナトリウムの軟膏剤化について研究した
結果長期間保存に耐える均質な軟膏の製法を見出したも
のである。Powder-like and ointment-like denture adhesives are used depending on the structure of the denture, its fit, and the preference of the wearer. Recently, powdered denture stabilizers containing sodium polyacrylate as the main ingredient have come into practical use due to their excellent adhesive fixing power, but as ointments have the aforementioned drawbacks, ointment-like products have not yet been put into practical use. It has not yet been achieved. As a result of research into making an ointment from sodium polyacrylate, the present inventor discovered a method for producing a homogeneous ointment that can be stored for a long period of time.
問題を解決するための手段
ポリアクリル酸ナトリウムの粉末粒子が前記のように油
脂類、グリコール類からなる基剤から分離する傾向を有
するのは本物質特有の界面性質によるものと考えられた
のでこの物質の粉末粒子と特殊な親和性をもつ物質を検
索する必要があった。Means for Solving the Problem The reason why powder particles of sodium polyacrylate tend to separate from the base material consisting of oils, fats, and glycols as described above was thought to be due to the interfacial properties unique to this material. It was necessary to search for substances that have a special affinity with powder particles of substances.
併しながら義歯安定剤は使用により必ず唾液ないし飲食
物と共に漸次嘆下されるものであるから人体に無害であ
ることが必要であり、かつ無刺激、無臭、無味であるこ
とが望ましいことは明らかである。本発明者はこれらの
厳しい制約の下に種々研究した結果、天然燐脂質である
大豆レシチンがこの目的に最も適することを見出して本
発明を完成した。天然燐脂質は卵黄、動物の臓器内から
も得られるが、大豆から抽出される大豆レシチンは通常
25〜35%の大豆油を混じて飴状として工業用(食品
加工用)に供給されており、本発明の目的にこの大豆レ
シチンが極めてよく適合することが見出された。大豆油
を混合していない固形レシチンを使用する場合にはあら
かじめ大豆油の如き食用油脂を加え飴状ないしペースト
状として使用に供すればよい。本発明の態様は以下の如
くである。However, since denture adhesives are inevitably consumed along with saliva, food and drink, they need to be harmless to the human body, and it is clear that they are desirably non-irritating, odorless, and tasteless. It is. As a result of various studies under these severe constraints, the present inventors have found that soybean lecithin, a natural phospholipid, is most suitable for this purpose, and have completed the present invention. Natural phospholipids can also be obtained from egg yolks and animal organs, but soy lecithin extracted from soybeans is usually mixed with 25-35% soybean oil and supplied for industrial use (for food processing) in the form of candy. It has been found that this soybean lecithin is extremely well suited for the purposes of the present invention. When using solid lecithin that is not mixed with soybean oil, it is sufficient to add edible fats and oils such as soybean oil in advance and use it in the form of a candy or paste. Aspects of the present invention are as follows.
通常食品添加物として市販されているポリアクリル酸ナ
トリウムの重量に対し、35〜60重量%の飴状大豆レ
シチンを加えて練和し、これを適宜の大きさのチューブ
に充填すれば総義歯の固定に適合する安定剤が得られる
。If you add 35 to 60% by weight of candy-like soy lecithin to the weight of sodium polyacrylate, which is usually commercially available as a food additive, and mix it, fill it into an appropriately sized tube, you can create a complete denture. A stabilizer is obtained that is compatible with fixation.
かくして得られた義歯安定剤を2時間毎に一5℃〜−7
℃の冷温と23℃〜26℃の室温に交互に10回づつ晒
す試験を行っても粉体と基剤である大豆レシチンとが分
離する傾向は全く認められず、長期にわたって均質な混
和相を保ち得る能力のあることが示された。本義歯安定
剤は無味で僅かに大豆油様の臭いを有する黄色のペース
ト状物で、衛生上無害である。次に本発明の実施例を記
述する。The thus obtained denture adhesive was heated to -5°C to -7°C every 2 hours.
Even when we conducted a test in which the powder was exposed to a cold temperature of 10°C and a room temperature of 23°C to 26°C 10 times each, there was no tendency for the powder to separate from the base soybean lecithin, indicating that a homogeneous mixed phase remained for a long time. It has been shown that they have the ability to maintain This denture adhesive is a tasteless yellow paste with a slight soybean oil-like odor, and is harmless from a sanitary standpoint. Next, embodiments of the present invention will be described.
実施例1
分子量約800万のポリアクリル酸ナトリウムの200
メツシュ通過粉末(日本化薬株式会社!り200gに大
豆レシチン(大豆油混合の食品添加物適合品)240g
を加えて均一に練和する。この練和物を20g入り金属
チューブに充填した。Example 1 Sodium polyacrylate with a molecular weight of about 8 million 200
200g of mesh passing powder (Nippon Kayaku Co., Ltd.) and 240g of soybean lecithin (food additive compliant product mixed with soybean oil)
Add and mix evenly. This kneaded product was filled into a metal tube containing 20 g.
このものをチューブの先端から押出して総義歯床の顎堤
弓粘膜接着面に少量づつ数ケ所に付着させて口腔内に装
着し噛みしめると義歯安定剤は周囲の水分を吸収して粘
膜面に粘着し、食事中も義歯の動揺を生ぜしめなかった
。Push this out from the tip of the tube and attach a small amount to the mucosal adhesive surface of the alveolar arch of the complete denture base in several places. When you insert it into your mouth and bite down, the denture adhesive absorbs surrounding moisture and sticks to the mucosal surface. However, the dentures did not move during meals.
水剤は必要に応じ義歯床面から流水でこれを容易に洗浄
除去することができる。なお本義歯安定剤の使用量は義
歯床の口腔粘膜への適合程度の良否により一定ではなく
、義歯装着者は経験により容易に適量を見出すことがで
きる。The liquid solution can be easily washed off with running water from the denture base surface if necessary. The amount of the present denture stabilizer to be used is not fixed depending on the degree of compatibility of the denture base with the oral mucosa, and denture wearers can easily find the appropriate amount through experience.
発明の効果
従前既知のポリアクリル酸ナトリウムは湿潤粘膜に対す
る強い粘着性と長い粘着持続時間とを有する点で優れて
いるがこれを軟膏剤へ適用するための適当な軟骨基剤と
して本発明による大豆レシチン又は食用油脂(例えば大
豆油)混合大豆レシチンの(重用にもとづきポリアクリ
ル酸ナトリウム含有義歯安定剤を軟膏状に製品化し、か
ようにして従来の粉末状製品とは別態様の義歯安定剤粘
着利用面を開発し1尋た。Effects of the Invention The previously known sodium polyacrylate is excellent in having strong adhesion to moist mucous membranes and long adhesion duration, and the soybean according to the present invention can be used as a suitable cartilage base for applying it to an ointment. Based on the heavy use of soybean lecithin mixed with lecithin or edible fats and oils (e.g. soybean oil), a sodium polyacrylate-containing denture stabilizer is commercialized in the form of an ointment, thus creating a denture stabilizer adhesive that is different from conventional powdered products. I developed the usage side and asked 1 question.
手続補正書
62、2.25
昭和 年 月 日
任・、
特許庁長官 黒 1)明 雄 殿 −二1、事件の
表示 昭和61年特許願第220217号2、発明
の名称 義 歯 安 定 剤3、補正をする者
事件との関係 出願人
名称 昭和薬品化工株式会社
4、代理人
7、補正の内容
(1) 明細書第8頁20行の後に次の文章を加入す
る。Procedural amendment 62, 2.25 Date: 1945 Hito, Commissioner of the Patent Office, Kuro 1) Mr. Akio-21, Indication of the case: Patent Application No. 220217, filed in 1988 2, Title of the invention: Denture stabilizer 3 , Relationship to the case of the person making the amendment Applicant name Showa Yakuhin Kako Co., Ltd. 4, Agent 7 Contents of amendment (1) The following sentence is added after line 20 on page 8 of the specification.
「実施例2
大豆油精製工程で副生物として得られた淡褐色ワックス
状大豆レシチン6部にオリーブ油4部を加え、窒素気流
下に50〜55℃に加温しつつ攪拌して均一に練和する
。冷後得られたオリーブ油加しシチン4部に平均分子量
約800万のポリアクリル酸ナトリウムの150メツシ
ュ篩通過粉末6部を加えて均一に練和する。この練和物
を20g入り金属チューブに充填した。このものを実施
例1と同様に義歯安定剤として使用し実施例1と同様に
良好な使用成績を得た。Example 2 4 parts of olive oil was added to 6 parts of light brown waxy soybean lecithin obtained as a by-product in the soybean oil refining process, and the mixture was stirred and kneaded uniformly while heating to 50-55°C under a nitrogen stream. After cooling, add 6 parts of sodium polyacrylate powder passed through a 150-mesh sieve with an average molecular weight of about 8 million to 4 parts of the olive oil-added cytin obtained and knead it uniformly. This product was used as a denture stabilizer in the same manner as in Example 1, and good results were obtained in the same manner as in Example 1.
実施例3
ワックス状の大豆レシチン6部に落花生油4部を加え以
下実施例2と同様に操作して、落花生油前レシチンとポ
リアクリル酸ナトリウムとの練和物20gを充填してな
るチ5−ブ入り義歯安定剤を得た。このものについて実
施例1と同様に実用試験を行った結果実施例1と同等の
使用成績を得た。Example 3 4 parts of peanut oil was added to 6 parts of waxy soybean lecithin, and the following procedure was carried out in the same manner as in Example 2 to prepare a cheese 5 made by filling 20 g of a mixture of peanut oil pre-lecithin and sodium polyacrylate. - Obtained a denture adhesive. A practical test was conducted on this product in the same manner as in Example 1, and as a result, usage results equivalent to those in Example 1 were obtained.
実施例4
沃素価950大豆レシチン7部に大豆油3部を加えて均
一に混和したのち、公知技術に属する油脂水素添加処理
法により水素添加する。かくして沃素価41を示し、か
つ常温で軟かいワックス状の水素添加物を得た。このも
のに等量の大豆油を加えて均一に練和し、更にこの全量
と等量のポリアクリル酸ナトリウム(前例使用と同一品
質のもの)を加えて均質になるまで練和する。この練和
物は金属チューブに充填可能であり、実施例1と同様の
実用試験により本発明の目的を満足させる使用成績を与
えた。」
(2)同書第8頁12行の“メツシュ”を「メツシュ篩
」と補正する。Example 4 3 parts of soybean oil was added to 7 parts of soybean lecithin with an iodine value of 950, and the mixture was mixed uniformly, and then hydrogenated by a known technology for hydrogenating fats and oils. In this way, a wax-like hydrogenated product having an iodine value of 41 and being soft at room temperature was obtained. Add an equal amount of soybean oil to this mixture and knead it uniformly, then add an equal amount of sodium polyacrylate (of the same quality as used in the previous example) to this total amount and knead until it becomes homogeneous. This kneaded product can be filled into a metal tube, and a practical test similar to that in Example 1 gave results that satisfied the purpose of the present invention. (2) "Metshu" on page 8, line 12 of the same book is corrected to "metsushu sieve."
Claims (2)
シチンとを練和してなる義歯安定剤。(1) A denture stabilizer made by kneading sodium polyacrylate and soybean lecithin mixed with edible oil and fat.
項記載の義歯安定剤。(2) Claim No. (1) in which the edible oil is soybean oil
Denture adhesive as described in Section 1.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61220217A JPS6377806A (en) | 1986-09-18 | 1986-09-18 | Denture stabilizer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61220217A JPS6377806A (en) | 1986-09-18 | 1986-09-18 | Denture stabilizer |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6377806A true JPS6377806A (en) | 1988-04-08 |
JPH0440323B2 JPH0440323B2 (en) | 1992-07-02 |
Family
ID=16747714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP61220217A Granted JPS6377806A (en) | 1986-09-18 | 1986-09-18 | Denture stabilizer |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6377806A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016179957A (en) * | 2015-03-24 | 2016-10-13 | ピアス株式会社 | Denture stabilizer |
-
1986
- 1986-09-18 JP JP61220217A patent/JPS6377806A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016179957A (en) * | 2015-03-24 | 2016-10-13 | ピアス株式会社 | Denture stabilizer |
Also Published As
Publication number | Publication date |
---|---|
JPH0440323B2 (en) | 1992-07-02 |
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