JPS63315001A - Method for sterilizing and deodorizing interior of shoes and insole used therein - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed Description of the Invention] <Industrial Application Field> The present invention provides a method for sterilizing and deodorizing inside shoes and an insole (shoe insole) used therein for preventing foot odor and preventing and treating athlete's foot. It is related to.

<Conventional Technology> Due to changes in lifestyle and people increasingly wearing shoes all day long, the number of people suffering from foot odor and athlete's foot has increased significantly.

A wide variety of methods for preventing and treating foot odor and athlete's foot, including folk remedies, have been proposed and tried.

However, even with these methods, it is presumed that it is difficult to completely eradicate the bacteria that cause athlete's foot present in the affected area. What's more, even if we were able to completely eradicate them, if the shoes that had been layered with them were used again, the bacteria that were inside those shoes would transfer to the feet and multiply again, and we would have to change shoes again. too,
We must consider that there is an infinite risk of coming into contact with the bacteria that causes athlete's foot, both at home and in public places.

In general, naphthiomate and other more powerful drugs processed into ointments and tinctures are not used to treat athlete's foot, but the athlete's foot fungus is not only present on the skin surface, but also inside the epidermis and on the nails. Due to the fact that it lives in the lower parts of the earth, there is currently no fully effective treatment.

<Problems to be Solved by the Invention> In view of the problems of the prior art, an object of the present invention is to provide shoes for preventing foot odor and preventing and treating athlete's foot using benzoic acid and/or salicylic acid. The purpose of the present invention is to provide a method for sterilizing and deodorizing interiors, and an insole for use therein.

Means for Solving the Problems As a result of intensive study on effective methods for preventing and treating foot odor and athlete's foot, the present inventors have developed a method for preventing and treating foot odor and athlete's foot. It is fundamentally important to create conditions that prevent the growth of bacteria and mold that cause these odors and athlete's foot throughout the interior of shoes, where most of these occur, and to create such conditions. We discovered that it is most effective to use benzoic acid and/or salicylic acid, which are volatile and have antibacterial properties, and to maintain a weakly acidic atmosphere, and through further efforts, we have arrived at the present invention. It is.

That is, the present invention provides an insole containing benzoic acid and/or salicylic acid, which produces 0.2 to 10 #j at about 33°C.
This is a method for sterilizing and deodorizing the inside of shoes, which is characterized by volatilizing these drugs at a rate of / hour.

In the present invention, it is particularly important to create a sufficient atmosphere of these drugs inside the shoe, and for this purpose, approximately 30% of benzoic acid and/or salicylic acid is added to the insole.
It should be released at a rate of 0.2-1 ONI/hour at 3°C. When the amount of these drugs released is less than 0.2 ay/hour, there is little or very little effect on preventing foot odor and athlete's foot. On the other hand, the greater the released amount of these drugs, the greater the bactericidal effect, but as the released amount becomes larger, the amount of drug required for sustained effect increases, leading to higher costs. Furthermore, eczema and rashes may occur on the feet. In order to prevent such problems from occurring, the amount of these drugs released must be 10 η/hour or less.

This object of the present invention is achieved by providing these drug sustained release parts in at least a portion of the insole.

Insoles are typically formed from resin-impregnated nonwoven fabrics or porous plastic sheets. Alternatively, the thickness is 1~
10 Maro's urethane foam, rubber sponge, etc., and 111
It is formed from a sheet-like material made by laminating 111 fabrics (111 knitted fabrics or non-woven fabrics) together.

Specific examples of insoles provided with benzoic acid and/or salicylic acid sustained release portions include resin-impregnated nonwoven fabrics, porous plastic sheets, sponges, etc. that form the insole, mill fabrics (111 knitted fabrics, nonwoven fabrics, etc.). ) By impregnating or kneading these drugs into the insole, the entire or part of the insole retains these drugs,
Some drugs are designed to control the amount of these drugs released.

In this case, the amount of these drugs released depends on the concentration of the drug solution,
Can be controlled by changing the value of the drug, 0
．． It is suitable for keeping the speed relatively low, such as 2 to 1j19/hour. Antibacterial activity is somewhat low due to the low release amount.

A second example to obtain a more reliable and lasting effect is to use a fabric such as a nonwoven fabric, an I-type fabric, or a knitted fabric made of microporous hollow fibers having holes penetrating in the outer circumferential direction. There are some insoles in which a hollow part impregnated with these drugs (drug holding body) is incorporated into the surface or inside of the insole to hold the drugs and control the release port of the drugs. In this case, since these drugs are present in the hollow fiber as microcrystals, the amount of these drugs released from the hollow fiber can be controlled by changing the concentration of the drug solution,
It can be controlled in the range of 0.2 to 10 mg/hour or more by changing the hollowness ratio or the form of the fabric made of hollow fibers, such as nonwoven fabric, woven fabric, or knitted fabric.

In the present invention, among the above-mentioned examples, the second method is preferred because it greatly increases the retention amount of these drugs and can sustainably release these drugs at a substantially constant value within the above range. Moreover, it is preferable because these drugs are stable with very little chance of falling off even when bending/stretching or photographing when wearing the insole.

The material of such hollow fibers is its strength as an insole,
Polyethylene terephthalate is particularly desirable because of its stability against benzoic acid and salicylic acid.

Although benzoic acid and salicylic acid may be used alone, it is more preferable to use them in combination because the antibacterial action will be synergistic.

As a method for impregnating the above-mentioned hollow fibers with such drugs, the hollow fibers may be immersed in a solution in which these drugs are dissolved in a solvent such as acetone, methanol, or ethanol, and the solution in which these drugs are dissolved is applied to the hollow fibers. This can be achieved by a method such as dropping contact.

In the present invention, when the drug carrier containing benzoic acid and/or salicylic acid is installed at the tip of the insole, that is, around the toes, with a size of 53 x 5 Also desirable.

The present invention will be explained in more detail with reference to Examples below. Parts in Examples and Reference Examples indicate parts by weight.

Reference Example 1 Creation of fabric consisting of sky and shell 297 parts of dimethyl terephthalate, 2 parts of ethylene glycol
65 parts, 53 parts of sodium 3.5-di(carbomethoxy)benzenesulfonate (11.7 mol% based on dimethyl terephthalate), 0.084 part of manganese acetate tetrahydrate, and 1.22 parts of sodium acetate trihydrate. The mixture was placed in a precision base glass flask, and transesterification was carried out according to a conventional method. After the theoretical amount of methanol had been distilled off, the reaction product was placed in a polycondensation flask equipped with a rectification column, and orthophosphoric acid was added as a stabilizer. 5
0.090 part of a 6% aqueous solution and 0.135 part of antimony trioxide as a polycondensation catalyst were added, and the mixture was reacted at a temperature of 275° C. for 20 minutes under normal pressure and under a degree of vacuum of 30 mm for 15 minutes. The intrinsic viscosity of the obtained copolymer was 0.405. The softening point was 200°C. After the reaction was completed, the copolymer was made into chips according to a conventional method.

15 parts of chips of this copolymer and an intrinsic viscosity of 0.64
0.85 parts of polyethylene terephthalate chips were mixed with IXO for 5 minutes in a Nauta mixer (manufactured by Line Iron Works), heated to 110°C for 2 hours in a nitrogen stream, and further heated to 150°C.
After drying for 7 hours, the mixture was melt-kneaded at 290° C. using a two-wheel screw extruder to form chips. The intrinsic viscosity of this chip is 0.520. The softening point was 262°C.

The chips were dried in a conventional manner and placed in a spinneret with a width of 0.05 mm.
MR, a circular slit with a diameter of 0.65 and a circular opening with two closed arcuate openings was used, and the fiber was spun according to a conventional method, and the ratio of the outer diameter to the inner diameter was 2 = 1 (hollow ratio 25 %)made. This raw yarn was 300 denier/24 filaments, and was drawn according to a conventional method at a draw ratio of 4.2 times to obtain a multifilament of 71 denier/24 filaments.

This multifilament was knitted into a knitted fabric, and after scouring and drying by a conventional method, it was boiled at 1% in a 1% caustic soda aqueous solution.
The fabric was treated at 1 temperature for 2 hours to obtain a fabric with an alkali reduction rate of 15%, a water absorption rate of 3 seconds, a water absorption rate of 83%, and a basis weight of 2509/rd.

Note that the water absorption rate and water absorption rate were measured by the following method.

(Water 1 test method (JIS-11018)) The above-mentioned fabric was washed with anionic detergent Zabu (manufactured by Kao Soap Co., Ltd.) at 0.0%.
The sample was washed 10 times with a 3% aqueous solution at 40°C for 30 minutes in a household electric washing machine, and then dried.
04cc) @ and measure the time until water' is completely absorbed by the sample and reflected light is no longer observed.

+b+ Water Absorption Measuring Method A sample obtained by drying a fabric is immersed in water for 30 minutes or more, and then dehydrated for 5 minutes in a dehydrator of a household electric washing machine. It was calculated from the weight of the dry sample and the weight of the sample after dehydration using the following formula.

Water absorption rate = [(Sample weight after dehydration - Dry sample weight) / (Dry sample weight)] x 100 (%) The hollow fibers obtained by the above method are scattered over the entire surface of the hollow fibers and arranged in the fiber direction. , and at least part of it was a hollow fiber having micropores that penetrated to the hollow part. Examples 1 to 3 and Comparative Example 1 5aA cut from the fabric made of the hollow fiber obtained in Reference Example 1 Benzoic vI (BA) and salicylic acid (SA) having the composition shown in Table 1 were dissolved in acetone and dropped onto a hollow fiber sample of ×5 cIR size, and then air-dried to remove acetone and only BA ( Samples for insole attachment were obtained, including those retaining Example 1), SA only (Example 2), BA and SA (Example 3), and those containing neither BA nor SA (Comparative Example 1).

The volatilization rate of acetic acid in these samples in a constant temperature bath at 33° C. was as shown in Table 1.

Regarding these samples, AATCC (Technical manual of
the Allerican Association
n of Textile CheliStS
According to the halo test of andColorists),
Antibacterial properties were evaluated based on the presence or absence of a halo and the size of the inhibition zone.

The results were as shown in Table 1.

The test bacteria include A.ni Staphylococcus (3, aureus).
.

and B: white fungus (l”, n+enterophyt
es) was used.

The odor of the preparation was determined by putting the test preparation into a shoe and smelling it when heated to 33°C.

Examples 4-5 Felt made of polyester fiber (thickness 2 rMn>
BAo on top of the cut into size 5GX5CIA
, 15g of SA and 1g of SA dissolved in 1g of acetone were dropped, and the acetone was removed by air drying to obtain a sample for an insole (Example 4). The volatilization rate and antibacterial properties of this sample were investigated in the same manner as in Example 1. In the case of this sample, the volatilization rate was 0.6 /hr at the beginning of use, but when half of the drug was volatilized, the volatilization rate was 0.
It was 3Itg/hr (Example 5) and showed a gradual decreasing trend.

The results of the antibacterial test are shown in Table 1.

Table 1 Antibacterial evaluation In the above table, ◎: large halo present, O: medium halo 1Δ: small halo, ×: no halo.

The insole of the present invention can be obtained by pasting this sample (benzoic acid and/or salicylic acid sustained release part) having the above performance on the surface of a normal insole or embedding it inside the insole. can.

Claims (1)

[Claims] 1. Sterilization in shoes, characterized by volatilizing benzoic acid and/or salicylic acid from an insole containing benzoic acid and/or salicylic acid at a rate of 0.2 to 10 mg/hour. Odor prevention method. 2. An insole in which at least a portion of the insole is provided with a sustained release portion of benzoic acid and/or salicylic acid. 3. A patent claim in which the benzoic acid and/or salicylic acid sustained release portion comprises a fabric made of microporous hollow fibers having holes penetrating in the outer circumferential direction, and benzoic acid and/or salicylic acid held within the hollow portion. The insole according to item 2 of the range.