JPS63158446A - Apparatus for measuring component in liquid - Google Patents

Abstract

PURPOSE:To simply measure the component in a liquid without operation loss, by detecting whether a buffer solution is present and a sensor is mounted and displaying the detection results by a notice pattern. CONSTITUTION:A liquid component measuring apparatus is constituted so that a sensor/buffer solution error notice pattern is displayed on a display part 39 when a measuring start/stop switch 32 is turned ON in such a state that a lid like member 38 is opened (1), when a sensor unit 35 is completely set to the lid like member (2) or when no buffer solution is received in a reaction tank (3). The sensor/buffer solution error notice pattern is constituted so that a character E is allowed to light by the first character part in a character display part 39 and the illustrations of the reaction tank and sensor in an illustration display part 39 light alternately.

Description

DETAILED DESCRIPTION OF THE INVENTION [Technical Field] The present invention relates to a liquid component measuring device used for measuring the concentration of a substance to be measured in a liquid, particularly glucose, uric acid, etc. in a body fluid.

[Background technology]

BACKGROUND ART Fluid component measuring devices that measure components in body fluids, such as glucose and uric acid, usually include a sensor that detects a substance to be measured in a sample fluid.

The sensor is immersed in the sample liquid and outputs an amount of electricity according to the concentration of the substance to be measured, and transmits the amount of electricity to the arithmetic control section. The arithmetic control section calculates the amount of electricity and displays it on the display section as a concentration measurement value.

When performing measurements using this in-liquid component measuring device,
Prior to measurement, work must be performed to calibrate the sensor by injecting a calibration solution into the buffer solution, and to inject the sample. Some large liquid component measuring devices used in frequently used locations such as hospitals and testing centers automate these tasks. However, large ones are expensive and are not suitable for home use. In other words, for example, many diabetic patients are instructed to measure their blood sugar levels not only in hospitals but also at home. is desired, and expensive ones are not suitable. For this reason, conventional home-use devices have not been equipped with automatic sample injection means unlike the large-scale in-liquid component measuring devices described above, and have been operated manually.

In addition to the above-mentioned injection work, the user has to perform other tasks such as setting up a reaction tank containing a buffer solution when making a measurement, resulting in complicated procedures and frequent operational errors. In particular, you may forget to set up a reaction tank that does not contain a buffer solution or forget to attach a sensor. Some users perform measurement operations without noticing such mistakes, and it takes time to notice the mistakes, resulting in wasted time.

[Purpose of the invention]

In view of the above circumstances, it is an object of the present invention to provide a small-sized liquid component measuring device that is 1. inexpensive, 4. and can be easily measured by anyone without operational loss.

[Disclosure of the invention]

In order to achieve such an object, the present invention provides a sensor that is immersed in a sample liquid stored in a reaction tank, detects a substance to be measured in this sample liquid, and outputs an amount of electricity corresponding to the amount of the substance to be measured. An in-liquid component measuring device comprising: an arithmetic control unit that calculates the amount of the substance to be measured based on the electrical quantity; and a display unit that displays the amount as a measured value based on the output from the arithmetic control unit. The presence or absence of the buffer solution and the presence or absence of the sensor attached are detected prior to injecting the test liquid into the buffer solution that is the base of the sample solution, and the buffer solution is not contained in the display section; Alternatively, the gist of the present invention is an in-liquid component measuring device characterized in that a notification pattern indicating that the sensor is not attached is displayed.

Hereinafter, embodiments of the present invention will be explained in detail with reference to the accompanying drawings.

Figures 1(a) and (bl) show the in-liquid component measuring device according to the present invention viewed diagonally from above.As shown in the figure, this in-liquid component measuring device includes a sensor BS, a reaction tank, 3
4 and a display section 39. As will be described in detail later, the display section 39 detects the presence or absence of a buffer solution and the presence or absence of a sensor attached, and displays a sensor/buffer error pattern. In this embodiment, reaction vessel 34 comprises a disposable container as shown in FIG. This disposable container is filled with a predetermined amount of a pH buffer solution (hereinafter simply referred to as "buffer solution") and sealed with a sealing material 34a such as aluminum foil. When in use, after peeling off this sealing material 34a, it is installed in the hole of the reaction tank installation part 41, as shown in FIG. is covered with a lid-like member 38. The sensor BS is incorporated into the sensor unit 35 and attached to the lid-like member 38. The rotating body 37 and the thermistor 36 can also be attached to the lid-like member 38. sensor BS
, the rotating body 37 and the thermistor 36 are all immersed in a predetermined position in the liquid of the reaction tank 34 when the lid-like member 38 is closed. The lid-shaped member 38 is formed with an injection port 40 for a calibration liquid and a sample liquid, so that these can be injected into the reaction tank 34 using a dropper or the like in the closed state. Measured values such as the concentration of the substance to be measured are displayed as digital values on the display section 39 after the amount of electricity output from the sensor BS is subjected to arithmetic processing as will be described later.

As shown in FIG. 2(a), the display section 39 displays the first to fourth
It is composed of a text display section 39a having four text sections and units, and an illustration display section 39b that displays schematic diagrams of reaction vessels, sensors, batteries, etc., and displays measured values in the text display section 39a. With,
By changing the display patterns of the character display section 39a and the illustration display section 39b, it is possible to notify various desired information related to measurement, such as abnormal operating conditions and operation timing. Figure 1(a), (
In b), 31 is a power switch, and 32 is a measurement start/stop switch. When the measurement start/stop switch 32 is turned on, the rotating body 37 is rotated to stir the buffer solution in the reaction tank 34, and measurement is started. The rotating body 37 has a magnet (not shown) in the stirring part that is immersed in the buffer solution of the reaction tank 34.
is built-in.

Therefore, when the drive magnet placed at the bottom of the reaction tank 34 is rotated by the motor, the rotating body 37 is rotated.

This in-liquid component measuring device incorporates a circuit as shown in FIG. That is, this circuit includes a battery 1, a constant voltage circuit 2. Voltage control circuit 3. Sensor BS, I/V conversion circuit 4. A/D conversion circuit 5, temperature detection circuit 8. It includes an arithmetic control section 6 and a display circuit 7.

The constant voltage circuit 2 uses the battery 1 as a power source and outputs a constant voltage based on the output from the battery 1.

The voltage control circuit 3 includes an operational amplifier OPI and resistors R1 to R6.
, and switches SWI and SW2. The switches SWI and SW2 are controlled from outside the circuit using relays or the like. The voltage control circuit 3 applies negative feedback to the single power supply operational amplifier OPI.
switch swi.

The configuration is such that the degree of negative feedback is switched by inserting a resistor R6 or providing direct feedback by closing or opening SW2. In other words, three types of constant voltage (in this example, +〇,
7V, +0.6V and OV).

In this embodiment, the sensor BS detects a glucose component in a liquid to be measured (blood), and has an enzyme such as glucose oxidase immobilized on an electrode such as platinum. When a voltage is applied to the sensor BS in the liquid to be measured,
A current is output according to the concentration of the substance to be measured, that is, the glucose component in the liquid to be measured.

The 1/V conversion circuit 4 is configured to apply negative feedback to a single power supply operational amplifier OP2 using a resistor R7 and a capacitor C, and converts the current output from the sensor BS into a voltage and outputs the voltage. .

The temperature detection circuit 8 includes a temperature detection element R consisting of a thermistor 36.
The temperature detected in step 11 is output as a voltage.

The A/D conversion circuit 5 A/D converts the output voltage of the I/V conversion circuit 4 and the output voltage of the temperature detection circuit 8, and outputs the result.

The arithmetic control unit 6 controls the closing and opening of the switches SWI and SW2 of the voltage control circuit 3 according to the measurement order, controls the measurement operation such as controlling the voltage applied to the sensor BS, and also controls the measurement operation according to the operation status. to display a predetermined display pattern on the display section 39. The digital values output from the A/D conversion circuit 5 in accordance with the output of the sensor BS and the output of the temperature detection circuit 8 are processed in the arithmetic control section 6 and output to the display circuit 7 to display the concentration of the substance to be measured, etc. is displayed on the display unit 39 as a measured value.

The normal measurement operation will be described. First, when the power is turned on, the arithmetic control section 6 switches the switch SW of the voltage control circuit 3.
Turn on only I. With this, the calculation control unit 6
The voltage applied to the sensor BS is set to -Ov, the output from the sensor BS is eliminated, and the initial state of measurement is maintained. At the same time, the display section 39 displays an initial pattern as shown in FIG.
It consists of all the patterns being lit for about 1 second at the same time. After that, a reaction tank set request pattern is displayed. The reaction tank set request pattern is shown in Figure 2 (b).
As shown in FIG.
The illustration of the reaction tank in b blinks. The reaction tank set request pattern is for prompting confirmation of whether the reaction tank 34 is set normally.

When the temperature of the reaction tank 34 is confirmed, the lid member 38 is closed. A sensor unit 35, a thermistor 36, and a rotating body 37 are attached to the lid member 38 in advance, and when the lid member 38 is closed, all of them face a predetermined position in the liquid of the reaction tank 34. As mentioned above, this is the case. The power switch 31 may be turned on after the lid-like member 38 is closed. Next, the measurement start/stop switch 32 is turned on. When the measurement start/stop switch 32 is turned on, the rotating body 37 rotates to stir the pH-lowering solution, and the display section 39 displays a pattern for waiting for the injection of the calibration solution and the liquid to be measured. The calibration liquid/test liquid injection waiting pattern is the second one.
As shown in Figures (C) to (F), the horizontal bar at the center of each character part of the character display part 39a lights up, and also blinks in sequence from the first character part to the fourth character part. It is configured. In other words, the progress of the standby state is notified by changing the position of the blinking horizontal bar one after another. At the same time,
The arithmetic control unit 6 opens the switch SWI so that the feedback path of the operational amplifier OPI in the voltage control circuit 3 passes only through the resistor R5. As a result, the voltage applied to the sensor BS becomes +0.7V. When a voltage of +0.7V is applied to the sensor BS, an inrush current flows once as shown in period T2 in Figure 4(a), but this gradually decreases and stabilizes at a predetermined output current. Head towards. After a predetermined time, the arithmetic control section 6 closes the switch SW2, and the operational amplifier OP
The feedback path of 1 is made to pass through resistors R5 and R6. As a result, the voltage applied to the sensor BS becomes + of the measurement voltage.
It becomes 0.6V. The reason why a voltage higher than the measurement voltage is applied once and then the measurement voltage is applied in this way is to quickly stabilize the output current of the sensor BS.

+0.6■ of the measured voltage from the beginning without going through these steps.
may be applied. At the point when the output current of the sensor BS becomes stable (point 21 in FIG. 4(a)), a calibration liquid injection request pattern is displayed on the display section 39. The calibration liquid injection request pattern consists of the illustration of the reaction tank in the illustration display section 39b lighting up and the illustration of the dropper on the left blinking as shown in Fig. 2 (as if seen in a phantom). This is a jig for injecting the calibration liquid. When the calibration liquid injection request pattern is displayed, the user injects a predetermined amount of the calibration liquid into the reaction tank 34 through the opening 40 of the lid-like member 38. In this embodiment, the calibration liquid is a glucose solution with a predetermined concentration. When the calibration liquid is injected, this is detected by the calculation control section 6, and a pattern during calibration is displayed on the display section 39. Calibration As shown in FIG. 2(h), the middle pattern is constructed by drawing the characters rcALJ using the second to fourth character parts in the character display part 39a and making them blink. The point at which the BS output current becomes stable (Fig. 4 (a)
up to 22 points) are displayed. When the output current is stabilized, a test liquid injection request pattern is displayed on the display section 39. The sample liquid injection request pattern, as shown in FIG. 2(i), consists of the illustration of the reaction tank in the illustration display section 39b lighting up and the illustration of the dropper on the right flashing. When the measurement liquid injection request pattern is displayed, the user pours a predetermined amount of the measurement liquid into the lid member 38.
is injected into the reaction tank 34 through the opening 40 of. When the liquid to be measured is injected, it is detected by the sensor BS, and based on its output, the arithmetic control section 6 causes the display section 39 to display a pattern during measurement. The measurement pattern, as shown in FIG. 2 (J), consists of ro 00J blinking in the second to fourth character portions of the character display portion 39a. The pattern during measurement is the point at which the output current of sensor BS is stabilized (
The display continues until point R3 in FIG. 4(a)). When the output current becomes stable, stable points PI, P2 . P3
Calculations are performed based on the output current to obtain the measured value,
The obtained results are displayed as numbers by the second to fourth character portions in the character display portion 39a, as shown in FIG. 2(k). In addition, Pl, P2. The output current value of P3 is stored in the calculation control section 6. After confirming that the measured value is displayed on the display section 39, the user turns off the measurement start switch 32, opens the lid-like member 38, and
The reaction tank 34 is taken out and the power switch 31 is turned off. Of course, every time - measurements are completed, the sensor unit 35. The thermistor 361 and rotating body 37 must be cleaned. Note that FIG. 4(b) shows changes in the voltage output from the I/V conversion circuit 4 in accordance with the output current of the sensor BS.

If measurements are to be taken continuously, each time the reaction tank 34 containing a new buffer solution is reset, and the measurement start switch 32 is turned on again. In this way, as in the first measurement, the display section 39 becomes the calibration liquid/test liquid injection waiting pattern.

In the case of continuous measurement, once the output current of sensor BS is stabilized,
The liquid to be measured injection request pattern is immediately displayed on the display unit 39. In other words, the calibration value is stored during the first measurement, and there is no need to perform calibration again when measurements are taken continuously. When the power switch 31 is turned off, this memory is erased, and when the power switch 31 is turned on again, the calibration liquid injection request pattern is displayed on the display 39, as in the case of the first measurement described above.
is now displayed. Therefore, the power switch 31 must be turned off after all measurements are completed.

The arithmetic control unit 6 is designed to be able to store up to nine previous measurement values unless the power switch 31 is turned off, so that it is possible to forget to record a measurement value and perform the next measurement. Even if this happens, there is no need to re-measure. The stored measurement values are displayed on the display section 39 by pressing the memory switch 33. In other words, pressing the memory switch 33 once will display the previous measurement value, pressing it twice will display the second measurement value, and so on.
The measured values up to the previous time are displayed one after another in the second column in the character display area 39a.
~ It is displayed in the fourth character part.

At the tenth time, the previous measurement value is displayed again. The first character part in the character display part 39a is
It is now possible to display the previous measurement value.

At the same time, a (colon) was placed between the measured values,
As shown in Figure 2 (1), it lights up to indicate that the memory value is being displayed. The memory switch 33 cannot be operated until the measurement start/stop switch 32 is turned on and the measurement results are displayed. This is because there is a risk of confusion if memory display is performed during the measurement stage.

The output current of the sensor BS is unstable if the temperature of the liquid to be measured is lower or higher than a predetermined temperature range.

Therefore, in this liquid component measuring device, if the liquid temperature deviates from a predetermined temperature range between the time the measurement start/stop switch is turned on and the measurement result is displayed, the display section 39 The low temperature notification pattern or high temperature notification pattern is displayed and the measurement is stopped. As shown in FIG. 2(m), the high temperature notification pattern uses the first character part in the character display part 39a to
is turned on, and the illustration of the reaction tank in the illustration display section 39b is made to blink or turn on. As shown in FIG. 2 (r), the low temperature notification pattern is to light up L using the first character part of the character display section 39a, and flash or light up the illustration of the reaction tank on the illustration display section 39b. It consists of The reason why the illustration of the reaction tank is blinked or lit is to indicate that there is an abnormality in the reaction tank 34. When the low temperature notification pattern or the high temperature notification pattern is displayed, the user either replaces the reaction vessel or waits until the temperature reaches a measurable temperature, and then turns on the measurement start/stop switch 32 to restart the measurement.

This in-liquid component measuring device is capable of: (1) when the measurement start/stop switch 32 is turned on with the lid member 38 open; (2) the sensor unit 35 is not completely set in the lid member; or (3) the reaction When there is no buffer in the tank 34, a sensor/buffer error notification pattern is displayed on the display section 39. The sensor/buffer error notification pattern is as shown in Figure 2 (0).
The first character in the character display section 39a lights up the letter E, and the illustrations of the reaction tank and sensor in the illustration display section 39b alternately light up. The reason why the illustrations of the reaction tank and the sensor are lit alternately is to indicate that there is an abnormality in either of them.

The method for detecting the above states ①, ②, and ② is as follows. That is, in a normal state, when the measurement start/stop switch 32 is turned on, a voltage of 0.7 V is applied to the sensor BS, as described above. Due to this application, the sensor BS temporarily outputs an inrush current, so that the I/V conversion circuit 4 becomes saturated on the negative side for a certain period of time (portion TA in the figure), as shown in FIG. 4 (bl). This saturation voltage is constant, and a numerical value of 7 is stored in the calculation control unit 6.When the measurement start/stop switch 32 is turned on, if the output voltage does not reach this stored saturation voltage, The sensor/buffer solution error notification pattern will be displayed.In other words, in the states of ■, ■, and ■, the sensor BS is not immersed in the buffer solution, so even if a voltage is applied, there will be no inrush current. In this way, the above conditions ■, ■, ■ are detected and the display part 3
Since the sensor/buffer error notification pattern is displayed at 9, there is no loss of operation when performing measurements without a buffer or without a sensor.

In addition, the following methods can also be used to detect the states (1), (2), and (2) above. That is, even when the sensor BS is not immersed in the buffer solution, the I/V conversion circuit 4 has an offset voltage. Since this offset voltage has some variations due to the circuit configuration, its maximum value is stored in the arithmetic control unit 6 (.On the other hand, when the sensor BS is immersed in the buffer solution, an offset current flows. This offset current also varies. However, the minimum value of the output voltage of the I/V conversion circuit 4 due to the offset current of the sensor BS is larger than the maximum value of the offset voltage. Therefore, the output current of the sensor BS is stable. Time point (Figure 4 (
By comparing the output voltage at 21 points in a) with the offset voltage stored in the arithmetic control unit 6, the above-mentioned ■, ■,
It detects the condition (2).

This in-liquid component measuring device detects, when the measurement start/stop switch is turned on, if a component other than the buffer solution is mixed in the reaction tank 34, that is, if the reaction tank has not been replaced with a new one, the display unit 39 The reaction tank replacement request pattern is now displayed. The reaction tank replacement request pattern is the second
As shown in the figure (pl), the first character in the character display section 39a lights up E, and the illustration of the reaction tank in the illustration display section 39b lights up or flashes. The reason why the illustration lights up or flashes is to indicate that there is an abnormality in the reaction tank.

This in-liquid component measuring device can also display on the display section 39 information such as the time to replace the battery, the time to replace the sensor, and the fact that the concentration of the component to be measured is outside the measurable range. As shown in Figure 2 (Q), the timing for battery replacement is determined by the arithmetic control unit 6.
When the controller detects that the battery voltage has fallen below a predetermined value, the illustration of the battery in the illustration display section 39b is displayed by blinking or lighting up. As shown in FIG. 2(r), the timing for sensor replacement is determined by the arithmetic control unit 6.
When the sensor detects that the calibration value is lower than a predetermined value, it is displayed by lighting or blinking an illustration of the sensor. By lighting up the horizontal bar under the second to fourth character parts in the character display part 39a, as shown in Figure 2<s+, it is displayed that the component to be measured is below the lower limit of the measurable range. , As shown in FIG. 2 (1), by lighting the horizontal bars above the second to fourth character parts in the character display part 39a, it is possible to confirm that the component to be measured exceeds the upper limit of the measurable range. Display.

The in-liquid component measuring device according to the present invention is not limited to the above-mentioned actual road side. For example, in the embodiment, information such as abnormal operating status or operation timing is announced by changing the display pattern of the text display area and the illustration display area, but instead of displaying text on the display area. I don't mind. Alternatively, the notification may be made by voice.

〔Effect of the invention〕

Since the in-liquid component measuring device of the present invention is configured as described above, anyone can easily measure it without any operational loss, even if it is a small device for home use. -It goes without saying that it is inexpensive and compact because it is small.

[Brief explanation of the drawing]

FIGS. 1(a) and 1(b) are perspective views of one embodiment of the in-liquid component measuring device according to the present invention, and FIGS.
) shows the closed state of the lid-like member, and the same figure (b)
The figure shows the state with the lid-like member open. Figure 2 (al to (1) shows each display pattern on the display unit, Figure 2 (al is the initial pattern, Figure 2 (b) is the reaction tank set request pattern, Figure 2 (e) to (f) (g) is a calibration liquid injection request pattern, (h) is a calibration in progress pattern, (i) is a test liquid injection request pattern, (0) ) is the pattern being measured,
The same figure (kl is the measurement result, (1) is the memory display, (m) is the high temperature notification pattern, (n) is the low temperature notification pattern, (0) is the sensor/buffer error notification pattern. , the same figure (p) is the reaction tank replacement request pattern, the same figure (q)
(r) is the sensor life notification pattern; (S) is the notification pattern for under-floor of the measurable range; (tl) is the notification pattern for over the upper limit of the measurable range. Figure 3 is a circuit diagram showing the internal circuit, Figure 4 (a) is a graph showing changes in the output current of sensor BS, and Figure 4 (b) is a graph showing the I/V conversion according to the output current. A graph showing changes in the voltage output from the circuit, and Fig. 5 is a perspective view of a disposable container serving as a reaction tank. 6... Arithmetic control section 34... Reaction tank 39... Display section 39a...Character display section 39b...Illustration display section BS...Sensor Figure 5 Procedural Amendment Statement (Relationship with the case of the person making the amendment, April 25, 1982, 3) Patent Applicant Address: Osaka 1048 Kadoma, Oaza, Fukadoma City Name (583'j) Representative of Matsushita Electric Works Co., Ltd. (Sadao Fujii 4, Actor 5, Date of amendment order)
-6, Specification subject to amendment and Drawing 7, Contents of amendment (1) From page 13, page 13, line 17 to line 1, page 18 of the specification: "There is a hailstorm on the sensor BS." The statement is corrected as follows. - Memory [The output current of the sensor BS after the voltage is applied and the voltage output from the I/V conversion circuit according to this output current change as shown in Fig. 4. The upper side shows the change in the output current of the sensor BS, and the lower side shows the output voltage of the I/V conversion circuit. Sensor B
When a voltage of +〇, 7v is applied to S, the period T in Fig. 4
As shown in 2, an inrush current flows once. When the inrush current flows, the output voltage of the I/V conversion circuit 4 immediately saturates to the negative side, and continues until the inrush current becomes equal to or less than a predetermined value. The saturation voltage time until this inrush current falls below the specified value (
TA) in Fig. 4 is detected, and the predicted value is calculated from the function of the saturation voltage time and the time until stabilization stored in the arithmetic control unit 6 as shown in Fig. 6. be. In addition to this, the predicted value can also be calculated by the following method. That is, in the above example,
The I/V conversion circuit 4 always becomes saturated when an inrush current flows, but the output voltage width of the I/V conversion circuit 4 is increased to prevent saturation. And the fourth
As shown by the chain line in the figure, the output voltage due to the rush current is monitored, and the slope (output voltage ΔV at a constant voltage Δt) immediately after this output voltage reaches its peak is detected, and as shown in FIG. The predicted value can also be calculated from a function of this slope (ΔV/Δt) stored in the arithmetic control circuit 6 and the time until the output current of the sensor becomes stable. In this way, when the maximum output voltage width of the I/V conversion circuit becomes large, it becomes possible to measure a liquid to be measured with a high concentration up to the full measurement capacity of the sensor BS. The arithmetic control section 6 applies a voltage of +0.7v to the sensor BS, and closes the switch SW2 so that the feedback path of the operational amplifier OPI passes through the resistors R5 and R6. As a result, the voltage applied to the sensor BS becomes +0.6V of the measurement voltage. The reason why a voltage higher than the measurement voltage is applied once and then the measurement voltage is applied in this way is to quickly stabilize the output current of the sensor BS. It is okay to apply the measurement voltage of +0.6 V from the beginning without going through these steps, at the point when the output current of the sensor BS is stabilized (point 21 in Figure 4)
Then, the calibration liquid injection request pattern is displayed on the display unit 39. The calibration liquid injection request pattern, as shown in FIG. This is a jig for injecting the calibration liquid.When the calibration liquid injection request pattern is displayed, the user pours a predetermined amount of the calibration liquid into the lid-shaped member 3.
8 into the reaction tank 34 through the opening 40. In this example, the calibration solution is a glucose solution with a predetermined concentration. When the calibration liquid is injected, this is detected by the arithmetic control section 6, and a pattern during calibration is displayed on the display section 39. As shown in FIG. 2(h), the calibration pattern is rC using the second to fourth character parts in the character display part 39a.
It consists of drawing the letters ALJ and making them blink, and is displayed until the output current of sensor BS stabilizes (point 22 in Fig. 4). When the output current is stabilized, a test liquid injection request pattern is displayed on the display section 39. The sample liquid injection request pattern, as shown in FIG. 2(1), consists of the illustration of the reaction tank in the illustration display section 39b lighting up and the illustration of the dropper on the right flashing. When the liquid to be measured injection request pattern is displayed, the user injects a predetermined amount of the liquid to be measured into the reaction tank 34 through the opening 40 of the lid-like member 38 . When the liquid to be measured is injected, this is detected by the sensor BS,
Based on the output, the arithmetic control section 6 causes the display section 39 to display the pattern being measured. The pattern during measurement is shown in Figure 2 ('')
As shown in , it is constructed by flashing ro OOJ in the second to fourth character portions of the character display portion 39a. The measurement pattern continues to be displayed until the output current of sensor BS becomes stable (point 23 in FIG. 4). When the output current becomes stable, stable points PL, P2. A calculation is performed based on the output current of P3 to obtain a measured value, and the obtained result is displayed as a number by the second to fourth character parts in the character display section 39a, as shown in FIG. 2 ('k). Is displayed. Note that Pi, P2. The output current value of P3 is stored in the calculation control section 6. After confirming that the measured value is displayed on the display section 39, the user turns off the measurement start switch 32, opens the lid-shaped member 38, takes out the reaction tank 34, and turns off the power switch 31. Of course, every time - measurements are completed, the sensor unit 35
Thermistor 361 rotating pair 37 must be cleaned. ” (2) On page 25 of the specification, lines 3 to 6, “Figure 4 (
a)...Graph,'' should be corrected as follows. Memory ``Figure 4 is a graph that vertically compares the change in the output current of the sensor BS and the change in the voltage output from the I/V conversion circuit according to this output current.'' (3) In the attached drawing. , Figure 4 is corrected as shown in the attached sheet.

Claims (4)

[Claims] (1) A sensor that is immersed in a sample liquid stored in a reaction tank to detect a substance to be measured in the sample liquid and outputs an amount of electricity corresponding to the amount of the substance to be measured; A component measuring device in a liquid, comprising a calculation control unit that calculates the amount of a buffer solution that is the base of the sample solution, and a display unit that displays the amount as a measured value based on the output from the calculation control unit. Before injecting the liquid to be measured, the presence or absence of a buffer solution and the presence or absence of the sensor attached are detected, and the buffer solution is not contained in the display section and/or the sensor is not attached. An in-liquid component measuring device characterized by displaying a notification pattern. (2) Detection of the presence or absence of a buffer solution in the reaction tank and the presence or absence of the sensor attached is performed by comparing the electrical output of the sensor immediately after voltage is applied with a predetermined value. The in-liquid component measuring device described in 2. (3) The detection of the presence or absence of a buffer solution in the reaction tank and the presence or absence of the sensor attached is performed by comparing a stable value of the electrical output of the sensor to which a voltage is applied with a predetermined value. The in-liquid component measuring device according to item 1. (4) The display unit is configured to display illustrations of a buffer solution and a sensor, and the notification pattern is configured by alternately displaying the illustrations of the buffer solution and the sensor. The in-liquid component measuring device according to any one of items 1 to 3.