JPS6287241A - Oil droplet-in-water type emulsion composition - Google Patents

Abstract

PURPOSE:To improve the long-period preservation stability by incorporating a specified nonionic surfactant, a specified stearic ester and a specified emulsification assistant into the titled oil droplet-in-water type emulsion composition contg. a specified vegetable crude drug. CONSTITUTION:The oil droplet-in-water type emulsion composition contg. a crude drug derived from a liliaceous succulent plant such as aloe or a crude drug derived from a cucurbitaceous vegetable such as cucumber, Luffa cylindrica and Trichosanthes cucumeroides is prepared. A lipophilic nonionic surfactant having 2.0-5.0 HLB and a polyethylene glycol stearic ester having 14-18 HLB are incorporated into the composition. Glyceryl monostearate, glyceryl isostearate, etc., are exemplified as the lipophilic nonionic surfactant and lauryl alcohol, stearyl alcohol, etc., are exemplified as the higher alcohol.

Description

[Detailed Description of the Invention] [Field of Industrial Application] The present invention relates to an emulsion composition containing an unprecedentedly large amount of crude drugs, and more specifically, an emulsion containing crude drugs that has excellent usability even after long-term storage. Concerning composition/things.

[Prior art]

In recent years, development of emulsified compositions containing various crude drugs has been actively conducted. this is.

The aim is to provide consumers with natural and highly safe cosmetics, and to respond to the health consciousness of consumers who want to maintain healthy skin by utilizing the unique natural recovery power of herbal medicines. be.

However, crude drugs generally contain ingredients that make the emulsion system unstable, and emulsified cosmetics containing large amounts of these ingredients lack long-term storage stability.

In addition, because of the problem of usability, many commercially available milk cosmetics containing crude drugs contain a small amount of crude drugs in order to improve the storage stability of the product. Cosmetics containing aloe vera are known as a typical example of such milk cosmetics containing crude drugs.

Aloe plants have remarkable efficacy such as ■ wound healing effect ■ cell activation effect ■ heat retention effect. Therefore, if you add the extract to cosmetics, it will prevent rough skin.

It is expected to have remarkable medicinal effects on cracks, chapped skin, etc. However, commercially available aloe-containing cosmetics contain at most about 0.1% of powdered or solid extract bundles, and do not fully exhibit the efficacy of aloe. In order to fully exhibit the above-mentioned medicinal effects of aloe, it is necessary to incorporate a large amount of extracted powder into cosmetics so that the concentration is close to that in the original plant. Specifically, it is necessary to incorporate at least 0.5% of extract powder into cosmetics.

However, for example, when aloe extract powder is blended into a cosmetic cream at a concentration of 0.5% or more, the emulsification system becomes extremely difficult due to the effects of water-soluble organic salts, water-soluble inorganic salts, etc. contained in aloe. This causes instability, and the usability of the resulting cosmetic after long-term storage deteriorates, resulting in a problem of reduced commercial value.

[Purpose of the invention]

The purpose of the present invention is to create an ice cream that can contain an unprecedented amount of herbal medicines from succulent plants of the Liliaceae family, such as aloe, or herbal medicines from plants of the Cucurbitaceae family, such as cucumber, loofah, and gourd, which is stable even when stored for a long period of time, and has excellent usability. An object of the present invention is to provide a medium oil droplet type emulsifier composition.

[Structure of the invention]

According to the present invention, herbal medicines from Liliaceae succulent plants such as aloe or
In an oil-in-ice emulsion composition containing herbal medicines from Cucurbitaceae plants such as cucumber, loofah, and gourd, HLB2 is added as an emulsifier.
．． O~5.0 lipophilic nonionic surfactant and HLB1
An oil-in-ice emulsion composition is provided, which contains polyethylene glycol stearate 4 to 18 and a higher alcohol as an emulsification aid.

That is, the present invention uses the above-described specific HLB as an emulsifier in order to obtain an oil-in-ice emulsion composition that is stable for long-term storage and has excellent usability even when a large amount of the above-mentioned herbal medicine is blended.
In addition to using a lipophilic nonionic surfactant having the following formula and polyethylene glycol stearate, a higher alcohol is used as an emulsification aid.

The present invention will be explained in more detail below.

The herbal medicine used in the present invention is obtained by extracting leaves, roots, stems, and fruits of succulent plants of the Liliaceae family, such as aloe, or plants of the Cucurbitaceae family, such as cucumbers and loofahs, by suitable known means. The form of crude drugs is either extracts or dried extract powders. When the dry extract powder is blended into cosmetics, it is used as is, and when the extract liquid is blended, the amount converted to the solid content is blended. This blending amount is 0 for the emulsified composition.
．． A suitable amount is 5 to 5% by weight (preferably 0.5 to 2% by weight).

Examples of lipophilic nonionic surfactants with HLB 2.0 to 5.0 used in the present invention include glyceryl monostearate, glyceryl isostearate, glyceryl monomyristate, glyceryl monooleate, sorbitan monostearate, and sorbitan. Examples include sesquistearate, sorbitan monooleate, sorbitan sesquioleate, sorbitan monoisostearate, propylene glycol monostearate, etc., but in order to obtain emulsions with high viscosity such as cream etc. It is appropriate to use a Moreover, it is preferable that the lipophilic nonionic surfactant is blended in the emulsion composition in an amount of about 0.5 to 2.5% by weight. If the amount is less than 0.5% by weight, the emulsifier system becomes too hydrophilic, making it difficult to obtain a stable oil-in-ice emulsion, and if it exceeds 2.5% by weight, it becomes lipophilic. This makes it difficult to obtain a stable oil-in-ice emulsion. Furthermore, in the present invention, polyethylene glycol stearate having an HLB of 14 to 18 is used as an emulsifier together with the lipophilic nonionic surfactant.

If the HLB is less than 14, the emulsifier system becomes too lipophilic, which is undesirable, and if the HLB exceeds 18, it becomes too hydrophilic, which is not suitable.

In addition, the amount incorporated is preferably 0.8 to 3.0% by weight in the emulsified composition; if it is less than 0.8% by weight, the emulsifier system becomes too lipophilic; %, it becomes too hydrophilic and a stable oil-in-ice emulsion cannot be obtained.

In addition, higher alcohols used as emulsification aids include:
Examples include lauryl alcohol, cetanol, stearyl alcohol, behenyl alcohol, hexyldecanol, octyldodecanol, etc., but those that are solid at room temperature are preferable as substances that improve stability, and the blending amount thereof is determined in the emulsified composition. A suitable range is 0.5 to 5.0% by weight.

In the present invention, as an emulsifier, )lLB2. o~5
．． 0 lipophilic nonionic surfactant and 1 (polyethylene glycol stearate ester of LB14-8),
By using higher alcohol as an emulsification aid,
It is possible to obtain an oil-in-ice emulsion composition in which a large amount of the crude drug can be blended and which is also excellent in usability after long-term storage.As the emulsifier, conventionally well-known emulsifiers such as fatty acid sodium salts and fatty acid potassium salts can be used. When using 7-ion surfactants such as fatty acid triethanolamine salts, alkyl sulfates, alkyl phosphates, and polyoxyethylene alkyl phosphates, due to the influence of water-soluble inorganic salts contained in crude drugs, This is because the anionic surfactant causes double decomposition.

It is not possible to obtain a sufficiently stable emulsion for a long period of use.

Furthermore, it is difficult to use cationic surfactants such as stearyltrimethylammonium chloride, cetyltrimethylammonium chloride, and lauryltrimethylammonium chloride in external preparations and skin cosmetics from the viewpoint of safety for the skin.

Furthermore, when a polymer thickener such as sodium polyacrylate, carboxymethylcellulose, carboxyvinyl polymer, methylmethacrylic acrylate copolymer, or hydroxyethylcellulose is used as an emulsion stabilizer,
The object of the present invention cannot be achieved because viscosity decreases due to the influence of water-soluble inorganic salts in the herbal medicine.

In the present invention, as an oil phase component forming the emulsified composition, waxes such as beeswax and spermaceti; hydrocarbon dimyristic acid such as liquid paraffin, petrolatum, ceresin, microcrystalline wax, squalane, and pristane; , higher fatty acids such as stearic acid and behenic acid; and esters such as isopropyl myristate, isopropyl palmitate, myristyl myristate, and octyldodecyl myristate.

Further, in the present invention, other special ingredients such as antioxidants, vitamins, ultraviolet absorbers, humectants, chelating agents, preservatives, bactericidal agents, etc. can also be added as appropriate.

〔Example〕 The present invention will be explained in more detail with reference to Examples.

Examples 1-3, Comparative Examples 1-9 Method for preparing emulsified composition> The aqueous phase as shown in Table 1 is maintained at 60°C.

While stirring this aqueous phase with a homomixer,
Add the oil phase as shown in Table 1, which has been mixed at 0°C, and emulsify uniformly. After emulsification, cool to room temperature while stirring with a paddle mixer. The aloe extract powder used was obtained by squeezing the raw grass, purifying it with activated carbon, and then drying it under reduced pressure, and 1 part was obtained from 100 parts of the raw grass. Therefore, if one part of this herbal medicine is blended into the composition, it means that 100% of the herbal medicine is blended into the composition as the original herb. Also,
The fragrance was added at about 50°C after emulsification.

<Test method for emulsified compositions> (1) Storage conditions and storage period of emulsified compositions Stored for 1 year at normal room temperature (2) Evaluation items ■Cream composition appearance (texture, gloss), consistency, stickiness to fingers Ease of removal, ease of spreading on the skin, ease of dissolving into the skin, presence or absence of separation ■ Emulsion composition appearance (texture, gloss), viscosity, fluidity, ease of removal from the container ease of spreading on the skin, ease of dissolving into the skin,
Presence or absence of separation (3) Evaluators: 10 testers who are skilled in sensory testing of cosmetics (4) Judgment criteria: 0: Excellent usability after long-term storage and excellent commercial value.

Δ: Usability after long-term storage is poor, and commercial value is reduced.

X: Usability after long-term storage is significantly poor, and there is no commercial value.

The test results are shown in Table-I.

From Table - ■, aloe extract powder is 1% (100% as original car)
), it is difficult to obtain an oil-in-water emulsion composition with excellent usability even after long-term storage with the combination of anionic surfactants and/or nonionic surfactants and/or higher alcohols. Not possible (Comparative Examples 1 to 7), but HLB
2.0-5.0 lipophilic nonionic surfactant and HLB
It can be seen that in the present invention, which combines an emulsifier made of polyethylene glycol stearate 14 to 18 and an emulsification aid made of a higher alcohol, an oil-in-ice emulsion composition with excellent usability after long-term storage can be obtained. .

Examples 4 to 7 The same tests as in Example 1 were conducted except that the aloe extract powder in Example 1 was replaced with the following herbal medicine. The results are shown in Table n. All formulation examples demonstrate that the emulsion composition is excellent in usability after long-term storage.

Table - ■ [Effect of the invention] The oil-in-water emulsion composition containing crude drugs of the present invention contains a lipophilic nonionic surfactant with an HLB of 2.0 to 5.0 and a polyethylene glycol stearate with an HLB of 14 to 18 as an emulsifier. By containing a higher alcohol as an emulsification aid, the product has excellent usability and improved commercial value even after long-term storage, even though it contains a large amount of the crude drug.

Claims (1)

[Claims] (1) Liliaceous succulent herbal medicine such as aloe or cucumber,
In an oil-in-water emulsion composition containing herbal medicines from Cucurbitaceae plants such as loofah and gourd, an emulsifier with an HLB of 2.0 to 5.
1. An oil-in-water emulsion composition characterized in that it contains a lipophilic nonionic surfactant of 0 and a polyethylene glycol stearate of HLB 14 to 18, as well as a higher alcohol as an emulsification aid.