JPS6225645B2 - - Google Patents

Info

Publication number
JPS6225645B2
JPS6225645B2 JP58252434A JP25243483A JPS6225645B2 JP S6225645 B2 JPS6225645 B2 JP S6225645B2 JP 58252434 A JP58252434 A JP 58252434A JP 25243483 A JP25243483 A JP 25243483A JP S6225645 B2 JPS6225645 B2 JP S6225645B2
Authority
JP
Japan
Prior art keywords
group
formula
hydrogen
topical
ace
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP58252434A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59130816A (ja
Inventor
Uein Watokinzu Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schering Plough Corp
Original Assignee
Schering Plough Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Corp filed Critical Schering Plough Corp
Publication of JPS59130816A publication Critical patent/JPS59130816A/ja
Publication of JPS6225645B2 publication Critical patent/JPS6225645B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
JP58252434A 1982-12-27 1983-12-27 医薬組成物 Granted JPS59130816A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45325782A 1982-12-27 1982-12-27
US453257 1982-12-27

Publications (2)

Publication Number Publication Date
JPS59130816A JPS59130816A (ja) 1984-07-27
JPS6225645B2 true JPS6225645B2 (enExample) 1987-06-04

Family

ID=23799812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58252434A Granted JPS59130816A (ja) 1982-12-27 1983-12-27 医薬組成物

Country Status (4)

Country Link
EP (1) EP0114333B1 (enExample)
JP (1) JPS59130816A (enExample)
AT (1) ATE55911T1 (enExample)
DE (1) DE3381850D1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3410732A1 (de) * 1984-03-23 1985-09-26 Hoechst Ag, 6230 Frankfurt Methode zur behandlung des glaukoms
US4885293A (en) * 1984-09-24 1989-12-05 Schering Corporation Antiglaucoma agents
ATE80311T1 (de) * 1985-07-03 1992-09-15 Schering Corp Glaukomhemmende zusammensetzungen und verfahren zu ihrer herstellung.
US4914090A (en) * 1985-11-01 1990-04-03 Schering Corporation Ophthalmic compositions
GB8626217D0 (en) * 1986-11-03 1986-12-03 Sandoz Ltd Pharmaceutical compositions
US5346887A (en) * 1987-10-06 1994-09-13 Abbott Laboratories Glaucoma treatment
US5036051A (en) * 1987-10-06 1991-07-30 Abbott Laboratories Glaucoma treatment
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
US5059589A (en) * 1988-09-08 1991-10-22 Abbott Laboratories Glaucoma treatment
EP0375319A3 (en) * 1988-12-19 1991-12-11 Merck & Co. Inc. Angiotensin converting enzyme inhibitors in the treatment of glaucoma
US5688770A (en) * 1989-12-14 1997-11-18 Schering Corporation Antiglaucoma compositions and methods
WO1999036062A1 (en) * 1998-01-16 1999-07-22 Alcon Laboratories, Inc. Topical administration of angiotensin-converting enzyme inhibitors
FR2794975A1 (fr) * 1999-06-16 2000-12-22 Raouf Rekik Medicaments opthalmologiques neuro et retino-protecteurs
PL352365A1 (en) 1999-06-16 2003-08-25 Rekik Elyes Ben Mohamed Raouf Neuroprotective and retinoprotective ophthalmologic medicines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
DE3174844D1 (en) * 1980-10-23 1986-07-24 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions

Also Published As

Publication number Publication date
DE3381850D1 (de) 1990-10-04
ATE55911T1 (de) 1990-09-15
EP0114333A3 (en) 1985-08-14
JPS59130816A (ja) 1984-07-27
EP0114333A2 (en) 1984-08-01
EP0114333B1 (en) 1990-08-29

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