JPS62209359A - Separator - Google Patents

Abstract

PURPOSE:To enable treatment having good working efficiency by accurately and rapidly performing a process for washing and separating a substance to be examined, by providing the station lifter of a container receiving the substance to be examined, a pipe used in both of the sucking and injection of water introduced in the receiving container and a control means for each means. CONSTITUTION:A pipe 5 used in both of the sucking of a liquid and the injection of water is introduced into the receiving container 9, which receives blood separated into a supernatant liquid 11 and a substance 12 to be examined on a centrifugal separator, on a rack by raising a station lifter 6. The whole of a head 4 is inclined to a counterclockwise direction in matching relation to the rising of the filter 6 and the pipe 5 advances into the receiving container 9 by a set value while sucks a liquid 11 from the leading end part thereof to suck up only the liquid so as to leave the substance 12 to be examined. After sucking-up, the injection of water is performed with appropriate force by the pipe 5 to wash the substance 12 to be examined under stirring and centrifugal separation is again performed to repeat operation. By this method, a process for washing and separating a large number of the substances to be examined is performed accurately and rapidly and the transfer of the receiver container is smoothly performed to enable treatment having good working efficiency.

Description

Detailed Description of the Invention (Field of Industrial Application) The present invention relates to a separator that can automatically separate blood components that have reacted with reagents from other components when testing and analyzing blood. It is something.

(Prior art) To test and analyze blood or its generated components, blood is reacted with, for example, a particulate reagent in a receptor such as a test tube, and the reacted components are precipitated by a centrifuge to form an upper layer. There is a method of removing the supernatant liquid and inspecting and analyzing this precipitated part.

In this method, in order to obtain highly accurate analytical results, it is necessary to ensure that the purity of the analyte (precipitated material) that has reacted with the reagent is high. The steps of washing and centrifugation are performed repeatedly.However, in the past, the removal of the supernatant after washing and centrifugation was done entirely manually or manually using simple equipment. Particularly when using a reagent in the form of particulates as described above, the removal of the supernatant liquid required skill, resulting in poor workability.

(Object of the Invention) The present invention has been made in view of the above-mentioned problems, and an object thereof is to provide a separator that performs a reliable separation process and has good workability.

(Structure of the Invention) The above object of the present invention is to provide a large number of receptors in which an analyte reacted with a reagent is precipitated. a station lifter that holds the stored racks and can be moved up and down; a head that has a pipe for both suction and water injection that enters into the receiver above the station lifter; and a head that is entirely tiltable;
It is characterized by comprising a transfer means that allows the rack to be freely transferred to the station lifter, and a control means that controls the movement of each operating means, and that the test object is separated from the supernatant liquid and washed. Achieved by separator.

(Embodiment) Hereinafter, one embodiment of the present invention illustrated in the drawings will be described.

FIG. 1 is a schematic front view showing the separator of this embodiment, and FIG. 2 is a partially enlarged view showing the main parts of the separation process.

As shown in FIG. 1, the separator 1 is equipped with at least a spatula (4) and operating controls on a stand (2). Nell 7 and rack 8
Transport means (not shown), etc. are provided. The head 4 has, for example, 50 units on its upper side that are used for both suction and water injection, e.
Eves 5 (hereinafter simply referred to as "nosoips") are regularly arranged downward at appropriate intervals, and racks 8 are arranged on the lower side.
A station lifter 6 is provided for holding. Then, the spatula P4 is supported on the stand 2 by the holding part 3.
For example, the tilt angle and speed of the head can be reliably controlled by a drive mechanism using a high-precision pulse motor or worm gear provided in the holding section 3.

In addition, the means for transporting the rack 8 holding a large number (for example, 50) of receptors 9 (test tubes, etc.) containing specimens may be, for example, a transiro belt conveyor, or a speed controllable motor may be used to transport the rack 8. It is possible to control the speed to 1.

The station lifter 6 can be freely raised to the upper side of the head or lowered to the lower side by a mechanism using, for example, a Zeel screw or a stepping motor. In addition, in the above-mentioned frame 2, for example, a water supply tank, a drainage tank,
The blower motor, pump, and other parts of the drive system are housed inside.

The operation of the separator 1 configured as generally described above will be described below.

First, a reagent in the form of particulates is poured into blood that has entered a plurality of receptors 9 to cause a reaction for a desired test or analysis to produce a test substance. Thereafter, the specimen 12 (see FIG. 2) is precipitated by centrifugation. on the other hand,
Turn on the power to the separator 1, turn on the automatic operation switch, and perform mode settings, cleaning settings, and cycle settings. Thereafter, the receivers 9 are taken out from the centrifuge and housed in a fixed number (50 samples) and clamps, and the rack 8 is placed on the belt conveyor of the separator 1 (the position shown in FIG. 1). Thereafter, the conveyor switch is turned on and the belt conveyor sets the rack 8 on the station lifter 6. At this time, the station lifter 6 is moved to its home position by pressing the rest switch and is lower than the position shown in FIG. It is in a state of descent. Therefore, the rack 8 transferred by the belt conveyor is slid onto the station lifter 6 from the conveyor.
Ru. Furthermore, since this sliding is configured to be performed extremely smoothly, rattling of the rack 8 is avoided.
This prevents troubles such as mixing of the supernatant liquid produced by centrifugation and the precipitate layer (test substance).

The rack 8 moved onto the station lifter 6 is fixed with a clamp. Continuing with station lifter 6
As the head rises, the entire head tilts as shown by the dashed line f in FIG. 1, and the pipe 5 performs suction and water injection with good timing.

The process using the e-build 5 will be explained in more detail with reference to FIG. 2.

As shown in FIG. 2, a supernatant 11 and a sample 12 (
The precipitate layer) contains separated blood. As the station lifter 6 moves upward to the head, the receiver 9
The vibrator 5 enters inside. Incidentally, the tube 5 is in a state where it can suck water into the cup 1 by the operation of the water suction pump. Also, the entire head is tilted counterclockwise (in the direction of the arrow) at an appropriate timing in conjunction with the rise of the station lifter 6.

As the station lifter 6 rises and the entire head tilts, the vibrator 5 reaches the supernatant liquid 11.
moves into the receptor 9 by a set amount while sucking up the supernatant liquid 11 from its tip. Further, the tip of the pipe 5 is appropriately tapered so as to be in contact with the inner surface of the receiver 9. Therefore, it is ensured that the supernatant liquid 1 is removed while leaving the sample 12 behind.
Send only 1 to the drainage tank. Further, after the suction of the supernatant liquid 11 is completed, the water injection valve provided in the head 4 is operated, and a certain amount (the set amount) of water is poured in with appropriate force by the ove 5. Water is poured at an appropriate inclination angle θ when the head 4 returns clockwise (in the direction of arrow B), or when the head 4 returns vertically. As a result, the specimen 12 is stirred, the water injected contains no impurities, and the specimen 12 is washed.

After the suction/water injection process is completed, the station lifter 6 performs a predetermined operation such as lowering to the lower side of the head, and the rack 8 is taken out from the head 4. Then, the receiver 9 is centrifuged again to precipitate the specimen 12.

By repeating the above steps a set number of times, the test object 12
The purity of this product increases, making it possible to perform highly accurate testing and analysis.

Although the above explanation deals with the case where there is only one rack 8, the conveyor holds multiple racks at a constant interval f.
Since it is constructed so that it can be processed continuously using a plurality of racks 8, a large number of specimens can be processed quickly.

(Effects of the Invention) As explained above, according to the separator of the present invention, it is possible to accurately and quickly perform the cleaning and separation processing steps for a large number of specimens, and also to remove the receiver containing the specimens. Since the transfer of the sample is carried out smoothly, it is possible to perform processing with significantly higher work efficiency than in the past, and it is also possible to easily prepare samples that do not contain impurities and are suitable for high-precision inspection and analysis. and can be obtained quickly.

[Brief explanation of drawings]

FIG. 1 is a schematic front view of a separator according to an embodiment of the present invention, and FIG. 2 is a partially enlarged view showing the main parts of the separation process. DESCRIPTION OF SYMBOLS 1... Separator, 2... Frame, 3... Holding part, 4...
...Head, 5...Nozobe for both suction and water injection, 6...
Station lifter, 7...control no sonnel,
8... Rack, 9... Receptor, Jl... Supernatant liquid,
12...Test object.

Claims (1)

[Claims] It has a station lifter that holds a rack containing a large number of receptors containing precipitated specimens that have reacted with reagents and can be moved up and down, and has a dual function of suction and water injection that enters into the receptors above the station lifter. The head has a pipe and can be tilted as a whole, a transfer means that allows the rack to be transferred to the station lifter, and a control means that controls the movement of each operating means. A separator characterized by separating from fresh liquid and cleaning.