JPS621410A - Precision filter device - Google Patents

Abstract

PURPOSE:To provide a device having a large filter area per unit cubic volume, comparatively free from clog or choke up, capable of removing germs and fine grains by installing a removable hollow fiber filter element inside the cartridge filter housing for precision filtration. CONSTITUTION:Both upper and lower ends of hollow fiber bundle are fixed to the liquid density with the fixed resin 12 and 13, being supported and protected by the support member 10 placed between the resin 12 and 13. The first cap 11 is mounted on the resin 12 located on the opening side of the hollow fiber 14. The hollow fiber filter element 4 thus assembled is set in the cartridge housing 1, having the first cap 11 and its support 7 removable under the condition of liquid denseness. The liquid to be filtered is fed into the housing 1 from the inlet 5, passes through the hole 16 of the support 10, and passes the surface of hollow fiber 14 through into the fine, small holes of hollow fiber, fine grains and microorganisms being filtrated and removed during the process. The filtered liquid flows through the inside of hollow fiber, the opening end 17, the inside of the first cap 11 and is discharged out of the outlet 6.

Description

Detailed Description of the Invention [Field of Industrial Application] The present invention relates to a precision filtration device for the purpose of sterilization and removal of particulates, in which a hollow fiber filtration element is removably attached to the housing of a cartridge filter. .

[Prior art] Filters conventionally used for precision filtration are disk types using membranes (for example, disk types manufactured by Hall Corporation, FM Incorporated, Millibore Co., Ltd., etc.). or,
Cartridge types in which a membrane is incorporated into the cartridge in a pleated manner, or a matrix such as Cotton is incorporated into the cartridge housing (e.g., Pall Corporation, FM Incorporated, Millibore Corporation, Sarsitorius Gesellschaft Mitsut. beschlenktel e
Cartridge types such as those manufactured by Haftsung, Gelman Science Inc., and Fuji Photo Film Co., Ltd. are the main types.

[Problems to be Solved by the Invention] In precision filtration, a disk type filter with high reliability of filtration accuracy is easily clogged because the amount of permeation per unit volume of the filter body is small. In addition, the amount of permeation per unit volume of the filter is lower than that of the disk type.
Large cartridge-type filters that use a matrix such as cotton as a filtration element have a fibrous irregular network structure and can remove fine particles and microorganisms on the μm order, but smaller ones Particulates and microorganisms can easily pass through, so they can be used as pre-filters, but they are not suitable as final filters. Like disc-type filters, membrane filters with pleated membranes are not suitable as final filters. It can be used as a final filter because it can remove particulates and microorganisms due to the uniform pore size, but since the membrane is folded into pleats, there is a high possibility of pinholes forming in the folds, reducing reliability. It was missing.

In addition, conventional filtration devices using hollow fibers are mainly used in the field of parallel filtration, such as ultrafiltration devices, dialysis devices, and reverse osmosis devices, and many have integrated filtration elements and housings. . Furthermore, a filtration device using hollow fibers in the field of vertical filtration is composed of a hollow fiber bundle and a ring-shaped holder at one end thereof, as disclosed in Japanese Patent Application Laid-Open No. 58-141801. Because there is no support to support the hollow fiber bundle, the strength of the hollow fiber bundle in the longitudinal direction is weak, making it difficult to use precision filtration cartridge filters such as those manufactured by Ball Corporation and FM Inc. mentioned above. could not be installed and used in the housing.

Therefore, an object of the present invention is to provide a precision filtration device that has a large filtration area per unit volume and is capable of sterilization and removal of particulates without clogging.

[Means for Solving the Problems] In order to achieve the above object, the present invention provides a fluid C! ! A removable filtration element is installed in the cartridge housing of a cartridge filter for filtration. and a support that holds the outer periphery of the hollow fiber bundle, at least one of the hollow fiber bundles being open at the end of each hollow fiber, and connecting the fluid flow path formed in the housing to the hollow fiber bundle. Each hollow membrane isolates at least two chambers, and the support body is located in the middle of the fluid flow path and has a structure that does not substantially block the flow of fluid, so that the filter body has a high permeation amount per unit volume. It was filtered as ll1cll.

[Example] Next, the present invention will be specifically explained with reference to the drawings.

Hollow fiber filtration element 4 showing the first embodiment of the present invention in Figure @1
is set within the cartridge housing l. The cartridge housing 1 is made by Pall Corporation,
Mc! The cartridge housing 1, which is one of the E-filtration applicable cartridge housings (for 10 inches), is composed of a lid body 2 and a housing 3. The OM body 2 has a fluid inlet 5 and a fluid outlet 6.
have. The hollow fiber filtration element 4 is attached to the holding part 7 of the lid body 2.
and the cartridge housing 1 by the holding part 8 of the housing 3.
The set is kept within.

The hollow fiber filtering element 4 is composed of a hollow fiber bundle 9 in which a large number of hollow fibers 14 are aligned, a support 10 on the outer periphery of the hollow fiber bundle 9, and a first gap body 11 provided at one end of the hollow fiber bundle. Hollow fiber bundle 9
The upper and lower M ends of are fixed resin (botting agent) 12.13
It is fixed in a liquid-tight state. As shown in FIG. 2, the upper part of each hollow fiber 14 is open at the end face of the fixed resin 12, and closed at the end face of the lower fixed resin 13. A support 10 is present between the fixed resins 12 and 13 to protect and support the hollow fiber bundle 9. The first cap body 11 is attached in a liquid-tight manner to the fixed resin 12 on the side where the end of the hollow fiber 14 is open. An O-ring 15 is attached to the neck of the first cap body 11, so that the first cap body 11 and the holding portion 7 can be removably connected in a liquid-tight manner. The support body 10 has a large number of communication holes 16.

The liquid to be filtered is led into the cartridge housing l from the fluid inlet 5 and passes through the micropores of the hollow fibers from the outer surface of the hollow fibers 14 through MAAlB2 of the support 10, and at this time, the liquid contained in the liquid to be filtered is Filters and sterilizes fine particles and microorganisms. The filtrate is hollow fiber! 4 through the hollow fiber open end 1
7 through the inner chamber of the $1 cap body 11 to the fluid outlet 6
is discharged from. However, the flow method of the liquid to be filtered can also be reversed.

Another example of the hollow fiber filter element 21 is shown in Fig. 7fS3.
Both ends of the hollow fiber bundle 9 are fixed in a liquid-tight manner with a fixing resin 12.18. Each hollow fiber 1 (both ends of which are fixed resin 12.
Openings (17, 19) are formed on the end face of 18. Further, the first cap body 11'' is attached to the upper part of the fixed resin 12, and the second cap body 20 is attached to the lower part of the fixed resin 18, respectively, in a liquid-tight state.

FIG. 4 shows a second embodiment of the precision filtration system in which hollow fiber filtration elements 4.21 shown in FIGS. This device is designed to be used as a The first cap body 11' of the hollow fiber filter element 21 is removably connected to the holding part 37 in a liquid-tight manner. The first cap body 11 of the hollow fiber filtration element 4 is removably connected to the second cap body 20 of the hollow fiber filtration element 21 in a liquid-tight state. The liquid to be filtered is fluid inflow 03
5 into the housing 31, passes through the communication hole 16 of the support 10 of the hollow fiber filtration element 21.4, passes through the fine pores of each hollow membrane from the surface of each hollow fiber bundle 9, and at this time, the Filters and sterilizes fine particles and microorganisms contained in the filtrate.

The filtrate filtered and sterilized by the hollow fiber filtration element 4 passes through the hollow fiber, passes through the inner chambers of the cab body 11 and the second cap body 20, and then passes through the hollow fiber filtration element 4. The fluid passes through the hollow system of 21, passes through the inner chamber of the first cap body 11', and is discharged from the fluid outlet 36. Similarly, the filtrate that has been filtered and sterilized by the hollow fiber filtration element 21 passes through the hollow fibers of the hollow fiber filtration element 21, passes through the first cap body 11', and is discharged from the fluid outlet 38. Ru. In this case, there is no problem even if the flow direction of the filtered liquid is reversed, and
20 inch precision filtration cartridge housing 31
A 20-inch hollow fiber filter element can also be used.

FIG. 5 shows a hollow fiber filtration element 51 showing an embodiment of 'S3.
The hollow fiber bundle 9, the support body 10, the first gear, the bushing body 52, the second cap body 53, the if packing 54. 2nd patch skin 5
Consists of 5. Both ends of the hollow fiber bundle 9 are fixed resin 5B,
57 and is fixed in a liquid-tight state. Both ends of the hollow fiber 14 are open (5B, 58) at the end faces of the fixed resins 5G, 57. The first cap body 5 is attached to the end face of the fixed resin 5B, 57.
2. The second cap body 53 is attached in a liquid-tight state. A first gasket 54 and a second gasket 55 are installed on the first cap body 52 and the second cap body 53, respectively.

This hollow fiber filtering element 51 is set in the cartridge housing l, and the first carrier, filter body 52 and holding part 7 are
It is liquid-tightly sealed with a gasket 54.

Further, the second cap body 53 and the holding portion 8 are liquid-tightly sealed by a second gasket 55. The liquid to be filtered.

The fluid is introduced into the cartridge housing 1 from the fluid inlet 5, passes through the communication hole 16 of the support 10, and passes through the micropores of the hollow fiber from the outer surface of the hollow fiber 14. At this time, the fluid contained in the liquid to be filtered is Filters and sterilizes particulates and microorganisms. The filtrate passes through the interior of the hollow fiber 14, passes through the hollow fiber open end 58, passes through the inner chamber of the first cap body 52, and is discharged from the fluid outlet 6. In addition, a hollow fiber filtration element 51 is installed inside the 20-inch precision filtration cartridge housing 31 shown in FIG.
It is also possible to set two in series. In this case, the flow direction of the liquid to be filtered may also be reversed.

The WSG diagram shows a third embodiment in which a protector is arranged around the outer periphery of the hollow fiber bundle, and a hollow fiber filter element 71 in this embodiment.
are hollow fibers 9 and supports 10. ! 1 cap body 72, 2nd cap body 73, 1st packing 74, 2nd packing 75,
It is composed of a hollow fiber bundle protector 80.

The outer periphery of the hollow fiber bundle 9 is covered with a hollow fiber bundle protector 80, and the outer periphery is further covered with a support 10. When inserting and setting the hollow fiber bundle 9 into the support 10, the hollow fiber protector 80 protects the hollow fiber outer wall from the support! By avoiding direct contact with 0, it is possible to prevent pinholes from occurring. Furthermore, when the liquid to be filtered flows from the outside to the inside of the hollow fibers, the hollow fiber bundle protector 80 functions as a filtration membrane for forward application, causing clogging of the micropores of the hollow fibers. It becomes possible to make it difficult. Although one embodiment of a hollow fiber filtration element having a hollow fiber bundle protector 80 has been shown, a hollow fiber bundle protector may also be installed in a hollow fiber filtration element as shown in FIGS. 2 and 3. It is possible.

Further, FIG. 7 shows the structure of a hollow fiber filtration element 81 equipped with double support bodies, inside and outside.This hollow fiber filtration element 81 consists of a hollow fiber bundle 80. It is composed of a support body 84, a first cap body 82, and an O-ring 83. A first support 85 exists on the outer periphery of the inner hollow fiber bundle 90, an outer hollow fiber bundle 90' exists on the outer periphery of the first support, and a second support 85 exists on the outer periphery of the outer hollow fiber bundle. There are 84.

Both ends of the hollow fiber bundle 90.80' are fixed in a liquid-tight manner with a fixing resin 88.8S. Fixed resin 88 of hollow fiber 81
The end face of the fixed resin 89 is open (S2), and the end face of the fixed resin 89 is closed.

A first resin is attached to the fixed resin 88 having the opening side end surface of the hollow fiber 91.
The carburetor 7 cab body 82 is attached in a liquid-tight manner. The first cap body 82 has an O-ring 83. This hollow fiber filtration element 81 is installed in the cartridge housing 1 for precision filtration.
Precision filtration can be carried out by setting the Since the supports 84 and 85 are present in two places, inside and outside the hollow fiber bundle, the overall strength of the hollow fiber filtration element 81 can be increased, and it is easy to operate and can be used in a cart as shown in FIG. Lee 7
It is possible to provide a hollow fiber filtration element that can more reliably set the hollow fiber filtration element 81 in the housing 1 in a liquid-tight state. The hollow fiber filtration element 81 having dual inner and outer supports is one example, and the types shown in FIGS. 3, 5, and 6 having dual inner and outer supports may also be considered. It will be done.

Further, FIG. 8 shows a fourth embodiment. This embodiment incorporates a hollow fiber filtration element 101 having double inner and outer supports to form a precision filtration device.

The hollow fiber filtration element 101 is composed of a hollow fiber bundle 10B, a first support 102, and a second support 103. The first support body 102 exists in the center, and the outside of the R1 support body 102 is
A hollow fiber bundle 106 is present around the periphery. There is a second support 103 on the outer periphery of the hollow fiber bundle 108 . Both ends of the hollow fiber bundle 106 are fixed in a liquid-tight manner with fixing resins 108 and 109. One end of the hollow fiber 107 is open (112), and the other end is closed. The first support body 102 has a communication hole 104 and an opening of the hollow fiber 107 (1
12) It has an opening 113 on the end side. Further, the $1 support 102 passes through the fixed resin 108, and the opening 113 of the first support communicates with the communication hole 104. Furthermore, the first support body 102 is fixed in a liquid-tight manner with a fixed resin 108. An O-ring 110 is provided near the open end 113 of the first support 102 . Furthermore, fixed resin 1
08 has an O-ring 111 on its outer peripheral surface. A communication hole 105 is present in the second support.

The hollow fiber filtration element 101 described above is set in the cartridge housing 1 for precision filtration, and the open end of the first support 102 is connected to the holding part 7 in a liquid-tight manner by a ring 110. ing.

The fixed resin 108 is set in the housing 3 in a liquid-tight state by an O-ring 111. The object to be filtered is introduced into the hollow fiber from the fluid inlet 5 and passes through the micropores in the hollow fiber wall, thereby filtering and sterilizing particulates and microorganisms contained in the liquid to be filtered. The filtrate that has passed through all the small holes in the hollow fiber wall passes through the inner holes of the R1 support 102 and is discharged from the fluid outlet. In this case, as before, the flow of the liquid to be filtered can also be reversed.

Note that the filtration element of a normal cartridge filter has an axial length A of 22 to 30 cm, so in order to use it in a 20-inch precision filtration cartridge housing as shown in FIG. Either two filtration elements having a length of 100 mm are used, or the axial length of the filtration elements is approximately 2A.

Although not shown, in the case of cartridge housings for 30-inch and 40-inch precision filtration, cartridge housings with axial lengths of 3A and 4A are used, or filtration housings with axial length A are used. The elements are used in three or four stages. By creating a module divided into several upper and lower stages like this, you can replace only the clogged filtration element.
It has good workability and can be done at low cost.

The same can be said of the embodiment shown in FIG. 11, which will be described later.

The filtration element 121 in FIG. 9 includes a hollow fiber bundle 9 and a support 1.
Consists of 0. Both ends of the hollow fiber bundle 9 are fixed in a liquid-tight manner with fixing resins 126 and 127. Hollow fiber 1
4 is open at the end surface of the fixed resin 126 and closed at the end surface of the fixed resin 127. An O-ring 125 is installed on the outer peripheral wall of the fixed resin 12G. The end face of the fixed resin 128 is sliced with a knife to open the end of the hollow fiber, so it is difficult to form a horizontal surface, and sealing with an O-ring at the end face as in conventional dialyzers lacks reliability. However, by sealing the outer peripheral wall of the fixed resin 126 with an O-ring, a more reliable liquid-tight connection can be achieved. Further, the support body 10 has a large number of communication holes 16. To set this filter element 121 in the cartridge housing 1,
A first connection cap body 122 is used. When setting the filtration element 121 in the cartridge housing 1 using the first connection cap body 122, the first connection cap body 122 as shown in FIG.
An O-ring 128 is attached to the c-type cap body 122.

It can be connected liquid-tightly to the lid body 2. The fluid flow is the same as described in FIG. In this case, the filtration element becomes clogged and the flow rate cannot be maintained, and when replacing the filtration element, only the filtration element 121 needs to be replaced, and the first connection cap body 122 is replaced in the same way as the cartridge housing. Since it can be reused, it has the advantage of being low cost.

Furthermore, another embodiment of the hollow fiber filter element is shown in FIG. 10, and the filter element 131 is composed of a hollow fiber bundle 9 and a support body 10. Both ends of the hollow fiber bundle 9 are fixed with resin 138 and 13.
7, it is fixed in a liquid-tight state. Both ends of the hollow fiber 14 are open at the end faces of the fixed resins 136 and 137. There are O-rings 135 and 134 on the outer peripheral walls of the fixed resin 13B and 137.
are installed respectively. Further, the support body 10 has a large number of communication holes 18. In order to set this filtering element 131 in the cartridge housing 1, the first connecting cap body 132 and the second connecting cap body 13 are attached to the upper and lower fixed resins.
3 can be removably fitted and used in the same manner as the filter element 121. Furthermore, since the filter element 131 is open at both ends, it can also be used in two rows as shown in FIG. A third straight cap body 138 is used to connect the two tree arrays. Furthermore, the first
Connection carrier, push body 132. The second connection cap body 133 is used by setting it in the cartridge housing in the same manner as described above. In FIG. 11, an example is shown in which filter elements 131, 131' of a rotary valve between both ends are connected in a two-way row, but instead of the filter element 131' of a rotary valve between both ends.
A filter element 131 of a rotary valve between both ends using a filter element 121 of a rotary valve between one end and a filter element 121 of a rotary valve between one end.
In any of these cases, each connection cap body can be replaced with a cartridge/
Since it can be reused like X-Ujifugu, it can realize low cost.

Furthermore, another embodiment of the connection cap body is shown in FIG.
The 1g1 connection cap body 182 has a packing material 168, and there are various types of cartridge housings that can maintain a liquid-tight state with this packing material 168 when connecting with the cartridge housing. It is more convenient to use this first connection cap body 162. In this way, if a connection cap body suitable for the cartridge housing is selected, only the low-cost filtering element needs to be replaced the next time, which is highly economical.

Regarding the above-mentioned method of connecting the filtration element and the connection cap body, the case where the O-ring is set on the filtration element side has been described, but the O-ring is set on the connection cap body. Good too.

Several embodiments of hollow fiber filtration elements have been described above, but 1. The invention is not limited to this.

The outer diameter of the hollow fiber of the present invention is preferably sooμm or less.If the area to be filtered is the same, if the outer diameter of the hollow fiber is 5QOμm or more, the hollow fiber will be easily soaked and the filtration amount will be small. As a result, the filtration accuracy decreases due to a decrease in the amount of filtration and the occurrence of pinholes.

The pore diameter of the micropores in the hollow fiber wall needs to be small in order to remove and sterilize particulates and microorganisms contained in the liquid to be filtered. The average pore diameter is preferably in the range of 0.01 to 1 #Lm, more preferably in the range of 0.1 to 0.5 μm. If the average pore size exceeds 1 μm, fine particles and microorganisms will not be effectively removed by filtration, and if the average pore size exceeds 0.
．． When the temperature is below 0 i p, m, filtration and sterilization of particulates and microorganisms are completed, but the filtration speed of the filtrate becomes slow and filtration takes time, making it impractical. Although there is no particular limitation, it is preferable to use olefin polymers whose main components are polyethylene, polypropylene, etc. Olefin polymers are inexpensive, have excellent chemical resistance, and have little eluate, so they are suitable for filtration elements. There is.

In addition, when water-repellent resin such as olefin-based polypropylene is used as the hollow fiber material, hydrophilic treatment such as corona treatment, oxidizing agent treatment, surfactant treatment, etc. may be performed on the inner and/or outer surface of the hollow fiber as necessary. However, by removably joining the cap of the hollow fiber filtration element to the hollow fiber bundle, the cap can be reused when replacing the hollow fiber filtration element, reducing costs. can.

Next, an experimental example will be shown to clarify the effects of the present invention.

[Experiment example] Outer diameter 300 JLm, inner diameter 200pm, porosity 40$,
Made of polyprolene with an average pore diameter of 0.2 μm [Mitsubishi Chemical Industries*
1 Co., Ltd. 4800J] (MI-25, density -0.90
5) ] 18,000 hollow fibers were bundled to create the hollow fiber filtration element shown in Figure 2. The effective filtration area was approximately 2.2 m.
It is.

The hollow fiber filtration element has an outer diameter of φ70+nm and a length of 250m.
It has a cylindrical shape of m. Fixed resin 12.13, support 10
The material of the cap body 11 is polypropylene. Two O-rings made of silicone rubber were attached to the cap body 11. As shown in 1ttz, this hollow fiber filtration element was assembled into a cartridge housing (IZXP) manufactured by FM Inc., and water at 20°C was directed from the outside to the inside of the hollow fiber at a rate of 0.3 kg/crn'.
When measured by the filtration flow rate, an average of 30 filtration flows per minute.

Comparative Example 1 Same pleated membrane L/7 cartridge FCC-22 (average pore diameter 0.22#Lm, effective filtration surface 10.42rn', dimensions: outer diameter = 70mm, length 250mm) manufactured by Fuji Photo Film Co., Ltd. When I measured the filtration flow rate of a cartridge housing (IZMP) manufactured by MF Inc., an average of 8.5 sentences flowed per minute.

Comparative Example 2 Milia Corporation's pleated membrane cartridge Duravore TPIO" (average pore diameter 0.22 m,
An effective filtration area of 0.7rn', dimensions: outer diameter = 70mm, length 250mm) was installed in the same way in the cartridge housing (IZ14P) of FM Inc., and the filtration flow rate was measured, and an average of 11 sentences per minute was obtained. The amount flowed.

[Effects of the Invention] Since the precision filtration device of the present invention uses a hollow fiber filtration element, it is possible to increase the effective filtration area with the same volume compared to a pleated membrane cartridge, so the filtration flow rate can be increased. It can be taken.

In pleated membrane cartridges, the membrane is folded into pleats, so pinholes often occur at the creases, making the filtration accuracy unreliable.However, the hollow fiber filtration element of the present invention has Since pinholes are less likely to occur and pinholes can be easily inspected and repaired, a stable filtration device with highly reliable filtration accuracy can be provided.

[Brief explanation of the drawing]

FIG. 1 is a sectional view of the first embodiment of the precision filtration device of the present invention, FIGS. 2 and 3 are sectional views of the filter element, and FIG. 4 is a sectional view of the second embodiment. FIG. 5 is a cross-sectional view of another filter element, FIG. 6 is a cross-sectional view of the third embodiment, and FIG. 7 to 9 are cross-sectional views of another filtering element, FIG. 10 is a cross-sectional view of a fourth embodiment using the filtering element of FIG. 9, and FIG. 11 is a cross-sectional view of yet another filtering element. Fig. 12 is a sectional view of a fifth embodiment using the filter element shown in Fig. 11. 1... Housing, 2. 3... Casing, 4... Filter element, 5...・Fluid inlet, 6...Fluid outlet, 7,
8... Holding part, 9... Hollow fiber bundle, 10.85.10
4...Support body, 11°11'...Cap body, 12
．． 13... Fixed resin, 20... Connection cap body, 8
0...protective body.

Claims (1)

[Claims] 1. A cartridge filter for filtration in which a filtration element is removably attached to a cartridge housing having a fluid inlet and an outlet, the filtration element having an inner surface and an outer surface connected to each other. It is composed of a large number of hollow fibers formed from hollow membranes having interconnected micropores and a support that holds the outer periphery of the hollow fiber bundle, and at least one of the hollow fiber bundles is open at the end of each hollow fiber. , the fluid flow path formed in the housing is separated into at least two chambers by each hollow membrane of the hollow fiber bundle, and the support is present in the middle of the fluid flow path and substantially restricts the flow of the fluid. A precision filtration device characterized by a structure that does not block the flow. 2. The precision filtration device according to claim 1, wherein the hollow fibers have an outer diameter of 500 μm or less. 3. The precision filtration device according to claim 1 or 2, wherein the average pore diameter of the micropores of the hollow membrane is in the range of 0.01 to 1 μm. 4. The precision filtration device according to claim 1, 2, or 3, wherein the hollow fibers are formed of an olefin polymer. 5. The precision filtration device according to any one of claims 1 to 4, wherein the inner and/or outer surfaces of the hollow fibers are subjected to a hydrophilic treatment. 6. The precision filtration device according to any one of claims 1 to 5, wherein a hollow fiber bundle protector having pores with a pore diameter of 1 μm or more is arranged between the hollow fiber bundle and the support. . 7. The axial length of the filter element A is 22cm to 30cm
A precision filtration device according to any one of claims 1 to 6. 8. A removable filtration element is installed in the cartridge housing of the cartridge filter for precision filtration, which has a fluid inlet and an outlet. A large number of hollow fibers are formed,
It is composed of a support body that holds the outer periphery of the hollow fiber bundle, and a cap body that is attached to one side of the hollow fiber bundle and can be detached from the cartridge housing, and the cap body is attached to the end of the hollow fiber bundle in a liquid-tight manner. A precision filtration device according to claim 1, which is joined. 9. The precision filtration device according to claim 8, wherein the cap body has a sealing member at the connection portion with the cartridge housing. 10. The precision filtration device according to claim 8 or 9, wherein the cap body is removable from the end of the hollow fiber bundle. 11. At least one end of the hollow fiber bundle is liquid-tightly fixed with a resin, and the end of each hollow fiber is open, and a sealing member is provided on the outer peripheral wall near the end.
The precision filtration device according to any one of Items 9 and 10.