JPS6173669A - Serum purification apparatus - Google Patents
Serum purification apparatusInfo
- Publication number
- JPS6173669A JPS6173669A JP59195832A JP19583284A JPS6173669A JP S6173669 A JPS6173669 A JP S6173669A JP 59195832 A JP59195832 A JP 59195832A JP 19583284 A JP19583284 A JP 19583284A JP S6173669 A JPS6173669 A JP S6173669A
- Authority
- JP
- Japan
- Prior art keywords
- plasma
- blood
- primary filter
- amount
- pump
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- External Artificial Organs (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明は、ポアサイズの異なる一次フイルター及び二次
フィルターの２種のフィルターを使用し、一次フィルタ
ーによって血液を血球成分と血漿成分に分離し、同時に
二次フィルターによって血漿を大分子量物質と小分子量
物質に分け、大分子量物質を廃棄し、補充血漿液を注入
する形式の血漿浄化装置の改良に関する。Detailed Description of the Invention (Industrial Application Field) The present invention uses two types of filters, a primary filter and a secondary filter, with different pore sizes, and the primary filter separates blood into blood cell components and plasma components. The present invention relates to an improvement in a plasma purification device that simultaneously separates plasma into large molecular weight substances and small molecular weight substances using a secondary filter, discards the large molecular weight substances, and injects supplementary plasma fluid.
（従来技術と問題点）
治療医学の進歩に伴って、ｆｆ１れた血漿浄化技術の必
要性が益々増大してきた。(Prior Art and Problems) With the progress of therapeutic medicine, the need for ff1 plasma purification technology has been increasing.
現在行われている血漿浄化方法では、図２に示すように
、一次フィルター（２）における動脈圧（Ｐｌ）と血漿
圧（Ｐｌ）を測定し、 （ｈ −Ｐｌ ）の１１！２間
圧力差を一定に保持するように１作動される。In the currently used plasma purification method, as shown in Figure 2, arterial pressure (Pl) and plasma pressure (Pl) are measured in the primary filter (2), and the pressure difference between 11!2 of (h - Pl) is measured. 1 is operated to hold constant.
血漿ポンプ（３）は動脈圧（Ｐ、）及び血ａ ｆＥ（Ｐ
ｌ）のそれぞれの圧力モニターとａｌＪ１器（４）で連
結しており、（ｐｌ−Ｐｚ ）の１１２１１３Ｉ圧カ差
が一定に保Ｉ−Ｙされるように血漿ポンプの回転がル制
御される。The plasma pump (3) pumps arterial pressure (P, ) and blood a fE (P
It is connected to each of the pressure monitors (1) by an alJ1 device (4), and the rotation of the plasma pump is controlled so that the pressure difference (pl-Pz) is kept constant.
しかし、この従来法においては、センサーによって測定
される一次フイルターの膜間圧力差は平均値的なもので
、′Ｘ際の圧力分布は一様でなく、局部的に異常に上昇
していることがあり、溶血が発生する恐れが多分にあり
危険であった。However, in this conventional method, the transmembrane pressure difference of the primary filter measured by the sensor is an average value, and the pressure distribution at 'X' is not uniform and may locally increase abnormally. This was dangerous because there was a high risk of hemolysis occurring.
（発明の目的）
本発明は、このような一次フィルターにおけるＲ血の危
険のない、血漿詐化装置を提供するものである。OBJECTS OF THE INVENTION The present invention provides a plasma fraud device without the risk of R blood in such a primary filter.
（発明の構成と作用）
本発明の骨子は、一次フィルターから抜き出す血漿量を
、一次フィルターに供給される血液量に比例するように
制御した点にある。(Structure and operation of the invention) The gist of the invention is that the amount of plasma extracted from the primary filter is controlled so as to be proportional to the amount of blood supplied to the primary filter.
本発明の装置においては、図１に示すように、人体より
抜き出された血液は血液ポンプ（１）で一次フィルター
（２）へ移送され、血球成分と血漿成分に分離される６
分離した血漿成分は血漿ポンプ（３）で抜き出される。In the device of the present invention, as shown in FIG. 1, blood extracted from the human body is transferred to a primary filter (2) by a blood pump (1) and separated into blood cell components and plasma components (6).
The separated plasma components are extracted by a plasma pump (3).
その際、一次フィルター（２）から抜き出す血漿量は、
血液ポンプ（１）で移送される血液量に比例した量にな
るように制御器（４）によって血漿ポンプ（３）の回転
を制御する。At that time, the amount of plasma extracted from the primary filter (2) is
The rotation of the plasma pump (3) is controlled by the controller (4) so that the amount of blood transferred by the blood pump (1) is proportional to the amount of blood transferred.
実際には、血漿ポンプの回転数の血液ポンプの回転数に
対する比すなわちｍ全ｄを
０−１ までの適当値に設定しておけば、血液の流量の
変化に応じて、血漿ポンプの筺贋は自動的に：ｌ！ｌ整
される。In reality, if the ratio of the rotational speed of the plasma pump to the rotational speed of the blood pump, that is, mtotal d, is set to an appropriate value between 0 and 1, the failure of the plasma pump will occur in response to changes in the blood flow rate. is automatically :l! l will be adjusted.
本発明の装こにおいても、安全運転の必要上、各部圧力
は従来′Ａ２１と同様モニターするが、その圧力に応じ
て流量調整を行わない点が従来装置と異なっている。In the device of the present invention, pressures at various parts are monitored in the same way as in the conventional 'A21' for the sake of safe operation, but the device differs from the conventional device in that the flow rate is not adjusted in accordance with the pressure.
（発明の効果）
本発明によれば、一次フィルターにおける膜間圧力差が
異常に高くなることがないので、溶血の発生が防止でき
る０本発明の装置は、血液流呈が少量の時に、特に有効
に作動する。(Effects of the Invention) According to the present invention, since the intermembrane pressure difference in the primary filter does not become abnormally high, the occurrence of hemolysis can be prevented. It works effectively.
図１は１本発明装置のブロック図０図２は、従来装置の
ブロック図である。
１血液ポンプ Ｐ１動脈圧
２一次フィルター Ｐ２血漿圧３血漿ポンプ
４制ＷμFIG. 1 is a block diagram of an apparatus according to the present invention. FIG. 2 is a block diagram of a conventional apparatus. 1 blood pump P1 arterial pressure 2 primary filter P2 plasma pressure 3 plasma pump 4 control Wμ
Claims (1)
の２種のフィルターを使用し、一次フィルターによつて
血液を血球成分と血漿成分に分離し、同時に二次フィル
ターによつて血漿を大分子量物質と小分子量物質に分画
する形式の血漿浄化装置において、一次フィルターから
抜き出す血漿量を、一次フィルターに供給される血液量
に比例するように、制御したことを特徴とする装置。Two types of filters, a primary filter and a secondary filter, with different pore sizes are used.The primary filter separates blood into blood cell components and plasma components, and at the same time, the secondary filter separates plasma into large molecular weight substances and small molecular weight substances. 1. A plasma purification device of the type that fractionates blood into two, characterized in that the amount of plasma extracted from the primary filter is controlled so as to be proportional to the amount of blood supplied to the primary filter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59195832A JPS6173669A (en) | 1984-09-20 | 1984-09-20 | Serum purification apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59195832A JPS6173669A (en) | 1984-09-20 | 1984-09-20 | Serum purification apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6173669A true JPS6173669A (en) | 1986-04-15 |
Family
ID=16347750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59195832A Expired - Lifetime JPS6173669A (en) | 1984-09-20 | 1984-09-20 | Serum purification apparatus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6173669A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56145859A (en) * | 1980-04-16 | 1981-11-12 | Kuraray Co | Treating device for blood |
| JPS5878668A (en) * | 1981-11-04 | 1983-05-12 | 株式会社クラレ | Blood treating apparatus |
-
1984
- 1984-09-20 JP JP59195832A patent/JPS6173669A/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56145859A (en) * | 1980-04-16 | 1981-11-12 | Kuraray Co | Treating device for blood |
| JPS5878668A (en) * | 1981-11-04 | 1983-05-12 | 株式会社クラレ | Blood treating apparatus |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term | ||
| S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
| R370 | Written measure of declining of transfer procedure |
Free format text: JAPANESE INTERMEDIATE CODE: R370 |