JPS6040303B2 - Double filtration plasma exchanger - Google Patents
Double filtration plasma exchangerInfo
- Publication number
- JPS6040303B2 JPS6040303B2 JP55098238A JP9823880A JPS6040303B2 JP S6040303 B2 JPS6040303 B2 JP S6040303B2 JP 55098238 A JP55098238 A JP 55098238A JP 9823880 A JP9823880 A JP 9823880A JP S6040303 B2 JPS6040303 B2 JP S6040303B2
- Authority
- JP
- Japan
- Prior art keywords
- molecular weight
- filter
- pump
- amount
- flow rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000001914 filtration Methods 0.000 title claims description 34
- 239000000126 substance Substances 0.000 claims description 29
- 210000004369 blood Anatomy 0.000 claims description 23
- 239000008280 blood Substances 0.000 claims description 23
- 239000012530 fluid Substances 0.000 claims description 12
- 210000000601 blood cell Anatomy 0.000 claims description 10
- 238000000926 separation method Methods 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 3
- 239000000306 component Substances 0.000 description 8
- 239000012528 membrane Substances 0.000 description 8
- 238000004820 blood count Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 208000007536 Thrombosis Diseases 0.000 description 3
- 238000009795 derivation Methods 0.000 description 3
- 206010019663 Hepatic failure Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000012503 blood component Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 208000007903 liver failure Diseases 0.000 description 2
- 231100000835 liver failure Toxicity 0.000 description 2
- 108010088751 Albumins Proteins 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000004715 ethylene vinyl alcohol Substances 0.000 description 1
- 238000002637 fluid replacement therapy Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 238000001631 haemodialysis Methods 0.000 description 1
- 230000000322 hemodialysis Effects 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- RZXDTJIXPSCHCI-UHFFFAOYSA-N hexa-1,5-diene-2,5-diol Chemical compound OC(=C)CCC(O)=C RZXDTJIXPSCHCI-UHFFFAOYSA-N 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 235000015205 orange juice Nutrition 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
Description
【発明の詳細な説明】
本発明は、二重ロ過型血数分離交換を安全にかつ安定し
て行なうための装置に関するものである。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a device for safely and stably performing double filtration type blood count separation and exchange.
啓不全、肝不全、自己免疫疾患等の治療法として近時血
数分離交換法が知られている。Recently, a blood count separation and exchange method has been known as a treatment for liver failure, liver failure, autoimmune diseases, and the like.
この方法は一般に血液透析と同じような手法により、閉
鎖体外循環回路中で血数を連続的に分離し、血球成分を
体内に返還する方法であるが、この場合廃棄される血嫌
中には高分子量の毒素等と結合した状態で低分子量有効
成分が含まれており、これをも除去すると、それだけ多
くの補液が必要となる。このため従来からこうした高分
子量物質を効率的に除共しようとする試みが種々行なわ
れており「中でも：重ロ過型血糠分離交換法が注目を集
めている。この方法は分子量ｃｕｔ‐ｏｆｆの異なる２
種類のロ過器を用い、第１のロ過器で血激成分と血球成
分とに分離した後、この血凝成分を第２のロ過器で高分
子量物質と低分子量物質とに分離し高分子量物質だけを
選択的に除去すると共に、低分子量物質は体内に返還さ
せる方法である。本発明はこのような方法をシステム化
するにあたって、閉鎖体外循環回路内の圧力や流量を自
動的にコントロールするとともに、適量の補液を供給し
、安全にかつ安定した二重ロ選型血数分離交換を行ない
得る装置を提供しようとするものである。This method is generally similar to hemodialysis, in which blood is continuously separated in a closed extracorporeal circulation circuit and blood cell components are returned to the body, but in this case, the discarded blood contains Low-molecular-weight active ingredients are contained in a state bound to high-molecular-weight toxins, and if these are also removed, more fluid replacement will be required. For this reason, various attempts have been made to efficiently remove these high molecular weight substances.Among them, the heavy filtration type blood bran separation and exchange method is attracting attention.This method is a molecular weight cut-off method. 2 different
After separating blood clot components into blood clot components and blood cell components in the first filter, the blood clot components are separated into high molecular weight substances and low molecular weight substances in the second filter. This method selectively removes high molecular weight substances while returning low molecular weight substances to the body. In systematizing such a method, the present invention automatically controls the pressure and flow rate in the closed extracorporeal circulation circuit, supplies an appropriate amount of replacement fluid, and performs safe and stable double selection type blood count separation. The aim is to provide a device that can perform the exchange.
第１図は本発明の一実施例を示したものでｔその構成を
作用と共に説明すると「まず患者から血液導入口１を通
してポンプＭ．により血液を導入し「一旦血液貯留器４
に貯留する。FIG. 1 shows an embodiment of the present invention.The structure and operation thereof will be explained as follows.First, blood is introduced from the patient through the blood inlet 1 by the pump M.
to be stored.
該血液貯留器４には圧力計Ｐ．が設けられており、続く
第ｌｏ過器５での目詰りその他の要因により異常高圧と
なるのをモニタ−している。この第１ロ過器５はポリビ
ニルアルコール膜等のロ過膜２によって仕切られており
、血液貯留器４から導入された血液は、血液導入側のポ
ンプＭ．の陽圧と、血数導出回路８１こ設けられたポン
プＭ２による陰圧により、前記ロ過膜２を介して血球成
分と血祭成分とに分離される。The blood reservoir 4 is equipped with a pressure gauge P. is provided to monitor abnormally high pressure caused by clogging in the subsequent LO filter 5 or other factors. This first filtration device 5 is partitioned by a filtration membrane 2 such as a polyvinyl alcohol membrane, and the blood introduced from the blood reservoir 4 is passed through a pump M on the blood introduction side. The blood is separated into blood cell components and blood cell components via the filtration membrane 2 by the positive pressure of the blood count deriving circuit 81 and the negative pressure of the pump M2 provided in the blood count deriving circuit 81.
ここで分離された血嫌成分は血糠導出回路８に設けられ
た皿競貯留器７及び９を通って第２ロ過器に送られるこ
とになるが、この分離された血競の圧力が設定圧を外れ
たような場合（例えば異常な陰圧を生じた場合）溶血等
を起す危険性がある。そこで本発明では、この第１ロ過
器６から第２ロ過器１１に至る血液導出回路８、本実施
例では前記ポンプＭ２の手前に設けられた血数貯留器７
に圧力計Ｐ２を設け、第１ロ過器５から導出される皿凝
の圧力を感知すると共に、この圧力計Ｐ２との連動制御
により前記ポンプＭ２の回転数を自動的に変え、もしく
は自動的にスイッチをＯＮ−ＯＦＦせしめることで、圧
力計Ｐ２が設定圧または設定圧以上となるように流量調
整するものである。The blood components separated here are sent to the second filtration device through the dish reservoirs 7 and 9 provided in the blood bran deriving circuit 8, but the pressure of the separated blood bran is If the set pressure is exceeded (for example, if abnormal negative pressure occurs), there is a risk of hemolysis, etc. Therefore, in the present invention, a blood lead-out circuit 8 from the first filter 6 to the second filter 11 is provided, and in this embodiment, a blood count reservoir 7 is provided in front of the pump M2.
A pressure gauge P2 is provided at the pump M2 to sense the pressure of the plate coagulated from the first filter 5, and the rotation speed of the pump M2 is automatically changed or automatically controlled in conjunction with the pressure gauge P2. By turning the switch ON and OFF, the flow rate is adjusted so that the pressure gauge P2 is at or above the set pressure.
例えばポンプＭ，による流量を１０Ｑ舷／分とした場合
、圧力計Ｐ２が−４０脚Ｈｇの設定氏となるようにポン
プＭ２の流量を１５〜２仇鷹／分にコントロールするも
のである。一方、前記第２０過器１１は内部がエチレン
ビニルアルコール膜等のロ過膜１０で仕切られてり、該
第２ロ過器１１に導入された皿酸は前記ポンプＭ２と後
記排出回路１２に設けられたポンプＭ８との流量差によ
って生ずる賜圧により、高分子量物質と低分子量物質と
に分離される。For example, if the flow rate of the pump M is 10 Q/min, the flow rate of the pump M2 is controlled to 15-2 Q/min so that the pressure gauge P2 is set at -40 Hg. On the other hand, the inside of the 20th filtration device 11 is partitioned by a filtration membrane 10 such as an ethylene vinyl alcohol membrane, and the dish acid introduced into the second filtration device 11 is transferred to the pump M2 and a discharge circuit 12 described later. Due to the pressure generated by the difference in flow rate with the provided pump M8, the substance is separated into a high molecular weight substance and a low molecular weight substance.
分離された高分子量物質は排出回路１２を通って導出さ
れ、貯留容器１３に排出されるが、この場合ポンプＭ２
と舷の流量がアンバランスになると第２０過器亀軍に異
常な圧力が加わり、安定したロ過・分離作用が得られな
い。そこで本発明ではポンプＭ２とＭ３の流量比を連動
制御して第２ロ過器１１における血酸導入量と高分子量
物質排出量の流量比を所定値に調整しているものである
。The separated high molecular weight substance is led out through the discharge circuit 12 and discharged into the storage container 13, but in this case, the pump M2
If the flow rate on the ship's side becomes unbalanced, abnormal pressure will be applied to the 20th filter unit, making it impossible to obtain stable filtration and separation effects. Therefore, in the present invention, the flow rate ratio of the pumps M2 and M3 is controlled in conjunction with each other to adjust the flow rate ratio between the amount of blood acid introduced into the second filter 11 and the amount of high molecular weight substances discharged to a predetermined value.
例えば前記ポンプＭ２の流量が１５〜２０脚／分であっ
た場合、ポンプＭ３の流量はその１夕３〜１′４良Ｐち
３〜５柳／分となるように自動的に制御されることにな
る。なお「図中Ｐ３は前記血嬢貯留器９に設けられた圧
力計であり、第２ロ過器１１もこ高圧が加わるとロ過膜
１０等がパンクする危険性があるため、この圧力計Ｐ３
でモニターしている。他方、前記第２ロ過器亀１で分離
された低分子量物質は導出回路１６を通って血液貯留器
１４に送られ、前記第１ロ過器１５から導出回路１７を
通って送られる血球成分と合流した後、患者の体内に返
還されることになる。For example, if the flow rate of pump M2 is 15 to 20 per minute, the flow rate of pump M3 is automatically controlled to be 3 to 1'4 per minute or 3 to 5 per minute. It turns out. Note that P3 in the figure is a pressure gauge installed in the blood reservoir 9, and if high pressure is applied to the second filtration device 11, there is a risk that the filtration membrane 10 etc. will be punctured.
is being monitored. On the other hand, the low molecular weight substances separated in the second filtration device 1 are sent to the blood reservoir 14 through the derivation circuit 16, and the blood cell components are sent from the first filtration device 15 through the derivation circuit 17. After merging with the patient, it will be returned to the patient's body.
また、前記第２０過器１ １において除去された血磯分
を補うため、補液容器１ ６からアルプミンやＨＥＳ等
の総液を導入回路１８を通して血液貯留器専科こ送って
いる。本発明ではこの補綴を導入するに際し、前記導入
回路１８に設けられた補液導入用のポンプＭと前記高分
子量物質の排出回路１２に設けられたポンプＭ３との運
動制御により高分子量物質の導出量と橘液の注入量とが
等量となるように流量調整するものである。例えば前記
したごと〈ポンプＭ３の流量が３〜５凧／分の場合、ポ
ンプＭ４もこれと同じ流量となるよう調整されるもので
あり、これにより補液は過不足なく血液貯留器１４に注
入されることになる。なお、本実施例では前記血液貯留
器１４に圧力計Ｐ４が設けられており、患者の状態（貧
血等）やシャントでのトラブルをモニターしている。本
発明による場合、上記した各ポンプＭ２，地，Ｍ４の連
動制御手段は電気的制御であってもよいが、他の手段と
して第２図に示すごとく、回路８のチューブ８ａと回路
１２，１８のチューフ１２ａ，１８ａの内蓬を変え、例
えばチューブ８ａの内蓬を８帆、チューブ１２ａ，１８
ａの内径を４脚として同一駆動ローラ２０でこれらチュ
ーブを同時にしごくようにすると、各チューブの径に応
じて流量調整が可能となる。In addition, in order to supplement the amount of blood removed in the 20th transducer 11, total fluids such as albumin and HES are sent from the replacement fluid container 16 to the blood reservoir through the introduction circuit 18. In the present invention, when introducing this prosthesis, the amount of high-molecular weight substances drawn out is controlled by the motion control of the pump M for introducing replacement fluid provided in the introduction circuit 18 and the pump M3 provided in the high-molecular weight substance discharge circuit 12. The flow rate is adjusted so that the amount of injected orange juice and the amount of citrus juice injected are equal. For example, as mentioned above, if the flow rate of pump M3 is 3 to 5 kites/min, pump M4 is adjusted to have the same flow rate, so that the replacement fluid is injected into the blood reservoir 14 in just the right amount. That will happen. In this embodiment, the blood reservoir 14 is provided with a pressure gauge P4 to monitor the patient's condition (anemia, etc.) and troubles with the shunt. According to the present invention, the interlocking control means for the pumps M2, M4, and M4 may be electrically controlled, but as another means, as shown in FIG. For example, change the inner length of the tube 8a to 8 sails, and change the inner length of the tubes 12a, 18a to 8.
If the inner diameter of a is made into four legs and the same driving roller 20 is used to simultaneously squeeze these tubes, it becomes possible to adjust the flow rate according to the diameter of each tube.
以上説明したものは本発明の一例であり、第１ロ過器５
や第２ロ過器ｌｉは中空糸型その他のタイプを用いても
よく、また他の機器類も本発明の趣旨に従って変更可能
である。What has been explained above is an example of the present invention, and the first filter 5
A hollow fiber type or other type may be used for the second filter li, and other devices may also be modified according to the spirit of the present invention.
このような本発明によれば、二重ロ過型血数分離を行な
うにあたり、第１ロ過器と第２ロ過器及び橋液回路を備
えた閉鎖体外循環回路内におし・て、血液成分や補液の
流量さらにはロ過膜の圧力が常に所定値となるように連
動制御されるため、きわめて安全で安定した治療が可能
となり、システム全体をコンパクト化できる。According to the present invention, when performing double filtration type blood count separation, the system is placed in a closed extracorporeal circulation circuit equipped with a first filtration device, a second filtration device, and a bridge liquid circuit, Since the flow rates of blood components and replacement fluids as well as the pressure of the filtration membrane are controlled in conjunction so that they always remain at predetermined values, extremely safe and stable treatment is possible, and the entire system can be made more compact.
また第２ロ過器の血液導入側に圧力計を設けることで、
第２ロ過器のロ過膜にに加わる圧力を常にモニタするこ
とができ、前記連動制御とあいまって安全性が向上する
、等その効果のすぐれた発明である。In addition, by installing a pressure gauge on the blood introduction side of the second filter,
This invention has excellent effects, such as being able to constantly monitor the pressure applied to the filtration membrane of the second filtration device, and improving safety in combination with the interlocking control described above.
第１図は本発明に係る装置の−実施例を示した概留図、
第２図は本発明の他の実施例を示した概留図である。
図中、５は第１ロ過器、８は血競導出回路、１１は第２
ロ過器、１２は高分子量物質排出回路、１５は低分子量
物質導出回路、１８は補液導入回路、Ｍ，，Ｍ２，Ｍ３
，Ｍ４はポンプ「Ｐ，，Ｐ２，Ｐ３，Ｐ４は圧力計を示
す。
第１図
第２図FIG. 1 is a schematic diagram showing an embodiment of the device according to the present invention;
FIG. 2 is a schematic diagram showing another embodiment of the present invention. In the figure, 5 is the first filter, 8 is the blood pressure deriving circuit, and 11 is the second filter.
filtration device, 12 is a high molecular weight substance discharge circuit, 15 is a low molecular weight substance derivation circuit, 18 is a replacement fluid introduction circuit, M, , M2, M3
, M4 is the pump P, , P2, P3, P4 are pressure gauges. Fig. 1 Fig. 2
Claims (1)
を備え、体内から導出した血液を第１のロ過器で血球成
分と血漿成分とに分離し、この血漿成分をさらに第２の
ロ過器で高分子量物質と低分子量物質とに分離するとと
もに、前記血球成分と低分子量物質を合流させ、補液を
加えた後、体内に返還する二重ロ過型血漿分離交換装置
において、該閉鎖体外循環回路中の前記第１ロ過器から
第２ロ過器に至る回路の途中に送液ポンプを設け、かつ
前記第２ロ過器の高分子量物質排出回路に前記ポンプと
の連動制御により、第２ロ過器の血漿導入量と高分子量
物質排出量の流量比が所定値となるよう流量調整可能な
ポンプを設け、しかも補液導入回路に前記第２濾過器の
高分子量物質排出回路に設けられたポンプとの連動制御
によつて該高分子量物質排出量と補液注入量が等量とな
るように流量調整可能なポンプを設けたことを特徴とす
る二重ロ過型血漿分離交換装置。 ２ 閉鎖体外循環回路中に第１のロ過器と第２のロ過器
を備え、体内から導出した血液を第１のロ過器で血球成
分と血漿成分とに分離し、この血漿成分をさらに第２の
ロ過器で高分子量物質と低分子量物質とに分離するとと
もに、前記血球成分と低分子量物質を合流させ、補液を
加えた後、体内に返還する二重ロ過型血漿分離交換装置
において、該閉鎖体外循環回路中の前記第１ロ過器から
第２ロ過器に至る回路の途中に送液ポンプを設け、かつ
前記第２ロ過器の高分子量物質排出回路に前記ポンプと
の連動制御により、第２ロ過器の血漿導入量と高分子量
物質排出量の流量比が所定値となるよう流量調整可能な
ポンプを設け、しかも補液導入回路に前記第２濾過器の
高分子量物質排出回路に設けられたポンプとの連動制御
によつて該高分子量物質排量と補液注入量が等量となる
ように流量調整可能なポンプを設けるとともに、前記第
２ロ過器の血漿成分導入側に圧力計を設けたことを特徴
とする二重ロ過型血漿分離交換装置。[Scope of Claims] 1. A closed extracorporeal circulation circuit is provided with a first filter and a second filter, and the first filter separates blood drawn from the body into blood cell components and plasma components. Then, this plasma component is further separated into high-molecular weight substances and low-molecular weight substances in a second filter, and the blood cell components and low-molecular weight substances are combined and, after adding replacement fluid, are returned to the body. In the filtration type plasma separation and exchange device, a liquid sending pump is provided in the middle of the circuit from the first filtration device to the second filtration device in the closed extracorporeal circulation circuit, and the second filtration device has a high molecular weight The substance discharge circuit is provided with a pump whose flow rate can be adjusted so that the flow rate ratio between the amount of plasma introduced into the second filtration device and the amount of high molecular weight substance discharged becomes a predetermined value by interlocking control with the pump; The feature is that a pump is provided that can adjust the flow rate so that the amount of the high molecular weight substance discharged and the amount of replacement fluid injected are equal by interlocking control with the pump provided in the high molecular weight substance discharge circuit of the second filter. A double filtration type plasma separation and exchange device. 2 A closed extracorporeal circulation circuit is provided with a first filter and a second filter, the blood drawn from the body is separated into a blood cell component and a plasma component by the first filter, and the plasma component is separated into a blood cell component and a plasma component. Furthermore, a second filtration device separates high-molecular weight substances and low-molecular weight substances, and the blood cell components and low-molecular weight substances are combined and, after adding replacement fluid, are returned to the body.Double filtration type plasma separation exchange In the apparatus, a liquid feeding pump is provided in the circuit from the first filter to the second filter in the closed extracorporeal circulation circuit, and the pump is provided in the high molecular weight substance discharge circuit of the second filter. A pump that can adjust the flow rate so that the flow rate ratio between the amount of plasma introduced into the second filtration device and the amount of high molecular weight substance discharged becomes a predetermined value is provided in the replacement fluid introduction circuit by interlocking control with the second filtration device. A pump is provided that can adjust the flow rate so that the amount of the high molecular weight substance discharged and the amount of replacement fluid injected are equal to each other by interlocking control with a pump provided in the molecular weight substance discharge circuit, and the plasma of the second filtration device is A double filtration type plasma separation and exchange device characterized by a pressure gauge installed on the component introduction side.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55098238A JPS6040303B2 (en) | 1980-07-18 | 1980-07-18 | Double filtration plasma exchanger |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55098238A JPS6040303B2 (en) | 1980-07-18 | 1980-07-18 | Double filtration plasma exchanger |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5722765A JPS5722765A (en) | 1982-02-05 |
| JPS6040303B2 true JPS6040303B2 (en) | 1985-09-10 |
Family
ID=14214373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP55098238A Expired JPS6040303B2 (en) | 1980-07-18 | 1980-07-18 | Double filtration plasma exchanger |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6040303B2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5930723U (en) * | 1982-08-21 | 1984-02-25 | 日立建機株式会社 | Wheel-type hydraulic excavator travel speed control device |
| JPS5996033U (en) * | 1982-12-21 | 1984-06-29 | 泉工医科工業株式会社 | blood processing equipment |
| JPS6099263A (en) * | 1983-11-02 | 1985-06-03 | 帝人株式会社 | Blood treating apparatus |
| JPS6113967A (en) * | 1984-06-29 | 1986-01-22 | 堀口 幸夫 | Artificial kidney apparatus |
| JPH0733936Y2 (en) * | 1988-05-11 | 1995-08-02 | 日立建機株式会社 | Wheel type hydraulic shovel running speed control device |
-
1980
- 1980-07-18 JP JP55098238A patent/JPS6040303B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5722765A (en) | 1982-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS583705B2 (en) | Double filtration plasma exchange device | |
| US4350594A (en) | Blood purification using plural ultrafiltration stages | |
| US4828543A (en) | Extracorporeal circulation apparatus | |
| US6083187A (en) | Method and apparatus for treating blood | |
| EP0223126B1 (en) | A system for the collection, treatment and return of a patient's blood | |
| WO1995007110A1 (en) | Blood pumping and processing system | |
| JPH04230853A (en) | Separation of blood plasma | |
| JPS6040303B2 (en) | Double filtration plasma exchanger | |
| US10500325B2 (en) | Wearable filtrating artificial kidney device | |
| JPS6040302B2 (en) | Double filtration plasma exchanger | |
| JPH06114102A (en) | Blood dialysis and filtration device | |
| JPS6327023B2 (en) | ||
| JPH059008Y2 (en) | ||
| JPH0244759Y2 (en) | ||
| JPH01104272A (en) | Blood treatment apparatus | |
| JPS60259270A (en) | Serum separation and replacement apparatus | |
| JPS6327024B2 (en) | ||
| JPS64940Y2 (en) | ||
| JPH0225407Y2 (en) | ||
| JPS60256465A (en) | Blood treating apparatus | |
| JPS62281956A (en) | Blood component removing apparatus | |
| JPH0359706B2 (en) | ||
| JPS6099263A (en) | Blood treating apparatus | |
| JPS62137062A (en) | Double filtering type blood treatment apparatus | |
| JPH043985B2 (en) |