JPS6156202B2 - - Google Patents
Info
- Publication number
- JPS6156202B2 JPS6156202B2 JP17019083A JP17019083A JPS6156202B2 JP S6156202 B2 JPS6156202 B2 JP S6156202B2 JP 17019083 A JP17019083 A JP 17019083A JP 17019083 A JP17019083 A JP 17019083A JP S6156202 B2 JPS6156202 B2 JP S6156202B2
- Authority
- JP
- Japan
- Prior art keywords
- temperature
- organ
- perfusion
- perfusate
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000000056 organ Anatomy 0.000 claims description 46
- 230000010412 perfusion Effects 0.000 claims description 29
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 16
- 239000008280 blood Substances 0.000 claims description 16
- 210000004369 blood Anatomy 0.000 claims description 16
- 238000007710 freezing Methods 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 230000008014 freezing Effects 0.000 claims description 12
- 210000003240 portal vein Anatomy 0.000 claims description 9
- 238000010257 thawing Methods 0.000 claims description 9
- 239000002577 cryoprotective agent Substances 0.000 claims description 8
- 210000003462 vein Anatomy 0.000 claims description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- 210000001367 artery Anatomy 0.000 claims description 6
- 230000036760 body temperature Effects 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 210000004204 blood vessel Anatomy 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 239000012530 fluid Substances 0.000 claims description 2
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 description 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 7
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 description 6
- 230000006378 damage Effects 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000007798 antifreeze agent Substances 0.000 description 4
- 238000002054 transplantation Methods 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 230000002528 anti-freeze Effects 0.000 description 2
- 230000008081 blood perfusion Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- VOPWNXZWBYDODV-UHFFFAOYSA-N Chlorodifluoromethane Chemical compound FC(F)Cl VOPWNXZWBYDODV-UHFFFAOYSA-N 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000000082 organ preservation Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17019083A JPS6061503A (ja) | 1983-09-14 | 1983-09-14 | 臓器の保存方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17019083A JPS6061503A (ja) | 1983-09-14 | 1983-09-14 | 臓器の保存方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6061503A JPS6061503A (ja) | 1985-04-09 |
| JPS6156202B2 true JPS6156202B2 (US06521211-20030218-C00004.png) | 1986-12-01 |
Family
ID=15900343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17019083A Granted JPS6061503A (ja) | 1983-09-14 | 1983-09-14 | 臓器の保存方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6061503A (US06521211-20030218-C00004.png) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6442205U (US06521211-20030218-C00004.png) * | 1987-04-25 | 1989-03-14 | ||
| JPH0417443Y2 (US06521211-20030218-C00004.png) * | 1987-01-26 | 1992-04-20 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0511317B1 (en) * | 1990-01-17 | 1998-04-22 | The Regents Of The University Of California | Composition to improve survival of biological materials |
| KR100767811B1 (ko) | 2006-10-25 | 2007-10-17 | 강원대학교산학협력단 | 이식 장기의 체외 관류방법 |
| JP2013075888A (ja) * | 2011-09-15 | 2013-04-25 | Tokyo Metropolitan Univ | 臓器保存装置 |
-
1983
- 1983-09-14 JP JP17019083A patent/JPS6061503A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0417443Y2 (US06521211-20030218-C00004.png) * | 1987-01-26 | 1992-04-20 | ||
| JPS6442205U (US06521211-20030218-C00004.png) * | 1987-04-25 | 1989-03-14 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6061503A (ja) | 1985-04-09 |
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