JPS6148482B2 - - Google Patents
Info
- Publication number
- JPS6148482B2 JPS6148482B2 JP13910577A JP13910577A JPS6148482B2 JP S6148482 B2 JPS6148482 B2 JP S6148482B2 JP 13910577 A JP13910577 A JP 13910577A JP 13910577 A JP13910577 A JP 13910577A JP S6148482 B2 JPS6148482 B2 JP S6148482B2
- Authority
- JP
- Japan
- Prior art keywords
- drug
- angina
- administration
- administered
- spasmus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000004004 anti-anginal agent Substances 0.000 claims description 4
- 229940124345 antianginal agent Drugs 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 2
- -1 propoxy(propoxy)-1H-indazole Chemical compound 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 14
- 229940079593 drug Drugs 0.000 description 14
- 239000003814 drug Substances 0.000 description 14
- HNNIWKQLJSNAEQ-UHFFFAOYSA-N Benzydamine hydrochloride Chemical compound Cl.C12=CC=CC=C2C(OCCCN(C)C)=NN1CC1=CC=CC=C1 HNNIWKQLJSNAEQ-UHFFFAOYSA-N 0.000 description 7
- 229960001689 benzydamine hydrochloride Drugs 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 239000003826 tablet Substances 0.000 description 7
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 206010010904 Convulsion Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 210000004351 coronary vessel Anatomy 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 235000019359 magnesium stearate Nutrition 0.000 description 3
- 230000003449 preventive effect Effects 0.000 description 3
- 229920002261 Corn starch Polymers 0.000 description 2
- CNBGNNVCVSKAQZ-UHFFFAOYSA-N benzydamine Chemical compound C12=CC=CC=C2C(OCCCN(C)C)=NN1CC1=CC=CC=C1 CNBGNNVCVSKAQZ-UHFFFAOYSA-N 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 235000010980 cellulose Nutrition 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000008120 corn starch Substances 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000008298 dragée Substances 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 230000000302 ischemic effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 description 2
- 239000007940 sugar coated tablet Substances 0.000 description 2
- 239000000829 suppository Substances 0.000 description 2
- 206010002388 Angina unstable Diseases 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 208000007814 Unstable Angina Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
- 230000001760 anti-analgesic effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 229960000333 benzydamine Drugs 0.000 description 1
- 238000002586 coronary angiography Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000007941 film coated tablet Substances 0.000 description 1
- 239000007888 film coating Substances 0.000 description 1
- 238000009501 film coating Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- 230000000004 hemodynamic effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 201000004332 intermediate coronary syndrome Diseases 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 239000003158 myorelaxant agent Substances 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 description 1
- 229960001597 nifedipine Drugs 0.000 description 1
- 238000010606 normalization Methods 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229960003712 propranolol Drugs 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 230000002966 stenotic effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13910577A JPS5473130A (en) | 1977-11-19 | 1977-11-19 | Antiistenocardia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13910577A JPS5473130A (en) | 1977-11-19 | 1977-11-19 | Antiistenocardia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5473130A JPS5473130A (en) | 1979-06-12 |
| JPS6148482B2 true JPS6148482B2 (cg-RX-API-DMAC7.html) | 1986-10-24 |
Family
ID=15237590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13910577A Granted JPS5473130A (en) | 1977-11-19 | 1977-11-19 | Antiistenocardia |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5473130A (cg-RX-API-DMAC7.html) |
-
1977
- 1977-11-19 JP JP13910577A patent/JPS5473130A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5473130A (en) | 1979-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR0164435B1 (ko) | 비만증 치료용 약제학적 조성물 | |
| JP2005515966A5 (cg-RX-API-DMAC7.html) | ||
| BG97108A (bg) | Използване на дифенилбутил пиперазинкарбоксамид при лечение на смущения,предизвикани от злоупотреба с вещества | |
| BG65856B1 (bg) | Използване на антагонисти на централни канабиноидни рецептори за получаване на лекарствени средства за улесняване спирането на консумацията на тютюн | |
| JP2002541097A (ja) | 線維筋痛症及び関連症状の治療におけるフルピルチン | |
| JP2007518755A (ja) | モノアミン神経伝達物質再取り込み阻害剤及びｎ−メチル−ｄ−アスパラギン酸（ｎｍｄａ）受容体アンタゴニストを含む医薬組成物 | |
| KR101951220B1 (ko) | 조합 als 치료법 | |
| JP2010065060A (ja) | 心不全処置のための複合治療 | |
| WO2020249602A1 (en) | Methods for treating pulmonary arterial hypertension | |
| JPS59112948A (ja) | コレステロ−ルレベル低下剤 | |
| JP2005533830A5 (cg-RX-API-DMAC7.html) | ||
| JP2004525143A5 (cg-RX-API-DMAC7.html) | ||
| JP2022177119A5 (cg-RX-API-DMAC7.html) | ||
| EP2830605B1 (en) | A combination medicament comprising phenylephrine and paracetamol | |
| WO1997006139A1 (en) | Inhibitor for narcotic analgetic dependence/resistance acquisition | |
| JP2001508769A (ja) | アレンドロン酸塩及び胃排出を促進する薬剤を含有する医薬組成物 | |
| KR890014109A (ko) | 의약제 | |
| JPS6148482B2 (cg-RX-API-DMAC7.html) | ||
| WO1997006800A1 (en) | Remedy for anxiety neurosis | |
| TW201806599A (zh) | 用於快速開始抗抑鬱作用之給藥方案 | |
| JP6420923B1 (ja) | 医薬 | |
| CA2612179A1 (en) | A pharmaceutical composition comprising loratadine and its use to treat patients with upper respiratory mucosal congestion | |
| JP2003513888A (ja) | 神経疾患治療用医薬品 | |
| CN1537006A (zh) | 含有米尔塔扎平和对乙酰氨基酚或一种非甾类消炎药的用于治疗头痛的联合用药物 | |
| WO2000021534A1 (en) | Pharmaceutical combination of ibuprofen-lysine and domperidone for treating migraine |