JPS6136726B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a deodorant composition, and more particularly to a composition for reducing armpit odor. It is well known that the unpleasant odor produced in the axilla is due to bacterial decomposition of apocrine gland sweat. There are numerous products on the market to treat the problem of foul-smelling sweating, and the most common product forms are lotions, which are usually applied from a roll-on applicator.
and aerosols. Many of these products contain ingredients that reduce the amount of sweat secreted, ie, they are antiperspirants. Most antiperspirants used are astringent aluminum compounds, and the use of aluminum hydroxychloride is very common. Astringent aluminum compounds also have a deodorizing effect on secreted sweat. The present invention relates to a composition having only a deodorizing effect,
That is, they do not obstruct the flow of sweat to any appreciable extent. The composition and method of action of deodorizers can be found in the "Handbook".
of Non-Prescription Drugs”, 1973 edition, no.
209 pages, Griffenhagen (GB
Griffenhagen) and LL Hawkins
“Deodorants” by Joseph R. Robinson, Washington State American Pharmaceutical Association, ed.
and Antiperspirants”. This article presents the active ingredients used in many trade name deodorant products. Many explanations for the causes of unpleasant body odors state that these are caused by the bacterial breakdown of apocrine sweat (e.g. Wells et al.
and Lubows' “Cosmehics and the
Cosmetics Science and
Technology” 2nd edition, Volume 2 (1972) No. 400
page). Many practical products are based on the use of fungicides such as hexachlorophene and various quaternary ammonium compounds. However, methods to overcome body odor have been proposed in the past. For example, the use of ion exchange resins to adsorb odorants found in axillary sweat has been suggested (U.S. Pat. No. 2,653,902;
(1953), J.invest.Derm. 23 411 (1954), and
J.Soc.Cosmet.Chemists. 7 256 (1956))
Products that use ion exchange resins as deodorizers are not commercially available (see "Cosmetics Science and
Technology”, 2nd edition, Volume 2 (1972), No. 403
page). Another method consists of masking unpleasant body odors with pleasant gradients (“Formulation and
"Function of Cosmetics" by Dr.Jelinetsk
Stephen Jellinek) (1970), No. 291
page). The use of antibiotics has also been suggested (“Cosmetics Science and Technology”) Part 2
Edition, Volume 2 (1972), p. 402). Other recently suggested deodorizing compounds are calcium, aluminum, magnesium or zinc salts of unsaturated aliphatic hydroxycarboxylic acids having at least 17 carbon atoms, such as zinc ricinoleate (UK Patent Specification No. 1282889); Esters of aliphatic or cycloaliphatic alcohols having 1 to 6 carbon atoms and mono- or dibasic aliphatic acids having 2 to 4 carbon atoms (UK Patent Specification No. 1487293): esters of certain alkanediphosphonic acids _C1 - _C6 alkyl ester (UK Patent Specification No. 1524167);
and the dimeric and trimeric zinc and magnesium salts of certain polycarboxylic acids, such as linoleic and linolenic acids (GB 2014453). As far as commercially available body deodorizers are concerned, these are primarily based on the use of disinfectants;
Continuous use of this agent is thought to be potentially damaging to the natural skin function (see GB Patent Specifications Nos. 1282889, 1487293, 1524167 and 2014453). It is an object of the present invention to provide novel deodorant compositions for reducing armpit odor in the form of lotions, gels or aerosols containing active ingredients that are neither astringents nor antibacterial agents. It is also an object to provide a composition having active ingredients capable of providing a deodorizing effect over a significant period of time, about 24 hours or more, and which is colorless, odorless and free of undesirable side effects. According to the present invention, a suspension comprising (a) a particulate deodorant active substance and (b) a liquid or gel-like medium containing less than 80% by weight of water as a carrier, without inhibiting the secretion of sweat. A deodorant composition for reducing axillary odor is provided, wherein the deodorant active ingredient is magnesium oxide, magnesium carbonate, lanthanum oxide or a mixture thereof. It will be understood from the foregoing that the deodorant composition of the present invention is also different from antiperspirant compositions that have a deodorizing effect. The active ingredients of the composition according to the invention have only a deodorizing effect. The deodorant compositions of the present invention therefore contain oxides, hydroxides or carbonates of zinc, magnesium or aluminum to inhibit the harmful corrosive effects of antiperspirant aluminum compounds on textiles. This differs from the aqueous antiperspirant compositions described in No. The compositions of the invention also differ from body powders or dusting powders which usually consist of a talc base and also contain other powdered ingredients such as magnesium carbonate (Harry's Cosmeticology).
Revised by JB Willkinnson (1973)
), p. 249). Magnesium carbonate is included in this preparation as a carrier for the fragrance (The Principles and Practice of Modern
"Cosmetics" by RG Harry, 1st edition (1948) Volume 2, p. 183 and "Perfume
Cosmetics and Soaps” Pouchier (WA
Poucher), 2nd edition (1925), Volume 1, No. 179
page). The deodorizing effect of talcum powders containing large surface area magnesium carbonates or oxides as well as other powders with large surface areas is based solely on the adsorption properties of large surface area powders, as described in "Der Schweiss" by HP Fiedler (1968). , p. 416, but the deodorizing effect of this powder has not been found. The ability to absorb and bind specific odorants is necessary and butylamine and ethyl mercaptan have been suggested as model compounds to assess the absorption potential of body deodorant actives (UK Patent Specification No. 2014453). In fact, it has been suggested to add a deodorizing agent effective against body odor to a powder containing a certain proportion of magnesium carbonate (British Patent Specifications Nos. 1,282,889 and 1,524,167). The deodorizing composition of the invention may be in the form of a lotion, the liquid medium as carrier for products of this type being usually a volatile alcohol, preferably ethanol or water and mixtures thereof, the amount of water being is preferably less than 60% by weight of the carrier medium. Other suitable carrier liquid media are well known to those skilled in the art. Deodorant lotions are typically applied to the skin from a roll-on applicator, but can be applied from other applicators; the liquid phase also typically provides the desired skin feel and retains the deodorant actives on the skin. Contains emollients to help. especially isopropyl myristate or other fatty acid esters,
For example, dibutyl phthalate and diisopropyl adipate are suitable, but other substances well known to those skilled in the art, such as cetyl alcohol, can also be used. A thickening agent is desirably included to help maintain the deodorant powder in suspension in the lotion. Preferably hydrophobic clays or colloidal silicas are used for this purpose. Hydrophobic clays are commercially available under the trade name Bentone, such as Bentone-34 or Bentobe-38. The preferred colloidal silica is
Aerosil200 (product name) and Cab-O-sil M-5
(Product name) and other grade products. Also included are cellulose derivatives, such as hydroxypropylcellulose (eg Klucel M). Roll-on compositions according to the invention are typically 10-
It contains 30% deodorant active, 1-30% emollient, 0.5 to 5% suspending agent, and the remainder consists essentially of alcohol or hydroalcohol. This deodorant active powder may also be incorporated into a vanishing cream base. These products primarily consist of water in which fatty substances such as cetyl alcohol or stearic acid are emulsified. The deodorizer products of the present invention in gel form include the usual ingredients providing a bar base in which the particulate deodorizer active ingredients are dispersed. The base typically comprises an alcohol or other aqueous alcohol thickened to form a gel with sodium stearate or other hardeners. The gel preferably also contains substances that improve skin feel, such as glycerol. These compositions usually contain about 10 to 30% by weight of powdered deodorant active ingredient. The deodorant composition may also be in the form of an aerosol;
The composition is packaged in an aerosol container with a gaseous propellant. This aerosol composition is of the type in which a powder is suspended in a liquid vehicle containing a mixture of a liquid medium as a carrier and a liquefied gaseous propellant. Aerosol compositions of the powder suspension type are well known to those skilled in the art. Liquid media as conventional carriers and liquefied propellants can be used in the aerosol compositions of the present invention, along with conventional suspending agents often included in these products to aid in suspending the active powdered ingredients. In particular, the formulation of antiperspirant powder suspension aerosols is well known and can be achieved by replacing the powdered antiperspirant active ingredient of this product with a powder of one or more of the deodorant active compounds mentioned above. The formulation of the deodorant product of the present invention is then accomplished. Aerosol powder suspension products in which the active powder ingredient is a deodorant are disclosed in British Patent Specification No.
Described in No. 1476117. In the products described in this prior specification, the deodorant active is an alkali metal bicarbonate. The deodorizing product according to the invention is a powder of magnesium oxide, magnesium carbonate, lanthanum oxide or a mixture thereof, as described in British Patent Specification No.
It can be made by substituting the sodium bicarbonate in the example of No. 1476117. The amount of powdered deodorizer active present in the aerosol compositions of the invention varies over a wide range, but is usually within the range of 0.5 to 15% by weight of the composition. A preferred amount is about 1 to about 10%, especially 1.5 to 5% by weight of the aerosol composition. The deodorant powder desirably consists of particles of 100 microns or less in diameter, and preferably consists of particles of essentially 100 microns or less in diameter.
Consisting of particles having dimensions between 70 and 70 microns. Liquid media as carriers are described, for example, in U.S. Pat.
As suggested in US Pat. No. 3,968,203, it may be a non-volatile, non-hygroscopic liquid. Liquid media as carriers with emollient properties are particularly useful, and many of these are illustrated in GB 1393860. Particularly preferred are fatty acid esters such as diisopropyl myristate and those shown in US Pat. No. 4,045,548, such as dibutyl phthalate and diisopropyl adipate. Various other liquid media as carriers for powder suspension aerosols are described in U.S. Patent No. 3,974,270.
No. 3949066, No. 3833721 and No. 3833720 and British Patent Specification No. 1411547, No. 1369872,
No. 1341748, No. 1300260 and No. 1476117. Volatile liquid media that can be used, such as ethanol, are also described in South African Patent Specification No. 75/
3576 and the use of volatile silicones is described in British Patent No. 1467676. The weight ratio of deodorant active to liquid medium as carrier can vary over a wide range and is from 0.01 to 3 parts, preferably from 0.04 to 1 part, of powder per part by weight of liquid medium. The liquefied propellant may be a hydrocarbon, a halogenated hydrocarbon or a mixture thereof. Examples of materials suitable for use as propellants are given in the aforementioned patents and include trichlorofluoromethane, dichlorodifluoromethane, dichlorotetrafluoroethane, monochlorodifluoromethane, trichlorotrifluoroethane, propane, butane, 1,1-difluoroethane, Contains 1,1-difluoro-1-chloroethane, dichloromonofluoromethane, methylene chloride and isobutane, singly or in admixture. Trichlorofluoromethane, dichlorodifluoromethane, dichlorotetraloroethane and isobutane, used alone or in mixtures, are preferred. It is common practice for aerosol powder spray compositions to include substances that assist in suspending the powder in the liquid vehicle. The substances prevent compaction of the powder and they also act as thickening or gelling agents for liquid vehicles. Hydrophobic clays and colloidal silicas are particularly suitable. Hydrophobic clays are Bentone, e.g. Bentone-34
or Bentone-38, and their use as suspending agents is disclosed in U.S. Pat.
It is described in many patent specifications including No. 3773683. Suitable colloidal silicas include Aerosil 200 (trade name) and Cab-O-sil M-5 (trade name) and other grades. The use of hydrophobic clays and colloidal silica to suspend powders in the manufacture of aerosol deodorant sprays is also described in British Patent Specification No. 1476117. Recently it has been shown that the expression of perspiration on the skin can be limited without the use of astringent antiperspirants by the application of solid particulate hygroscopic polymers that have the ability to absorb an amount of water at least equal to their own weight. British Patent Specifications No. 1485373, No. 1501862 and No.
Disclosed in No. 2003730. This water-swellable absorbent polymer can be included in the deodorizing composition of the invention described above which utilizes an anhydrous or substantially anhydrous carrier medium. Anionic polyelectrolyte absorbent materials are e.g. crosslinked etherified starches as described in German Patent Application No. 2702781 or US Pat. No. 4,117,222: US Pat. No. 3,589,364;
Sodium carboxymethyl cellulose cross-linked as described in U.S. Pat. No. 3,936,441 or No. 3,965,091; polyelectrolyte internally esterified as described in U.S. Pat. No. 3,678,031; Starch-acrylonitrile graft copolymer as described;
or polyacrylates crosslinked with polyamide/epichlorohydrin materials as described in German Patent Application No. 2614662; or U.S. Pat.
It is a potassium salt of polyacrylic acid crosslinked with aluminum ions as described in No. 4090013. These are insoluble in water to an extent of at least 40% by weight. According to another aspect of the invention, the powder comprises a mixture of a liquid propellant and a liquid medium as carrier, characterized in that the powder comprises a water-absorbing anionic polyelectrolyte and magnesium oxide, magnesium carbonate, lanthanum oxide or mixtures thereof. Powder suspension type aerosol products are provided in which the powder is suspended in a liquid vehicle. These aerosol compositions are preferably 0.5
or 15% by weight of a water-absorbing anionic polyelectrolyte and
Contains 0.5 to 15% by weight of deodorant active powder. This water-absorbing anionic polyelectrolyte can also be included in the anhydrous or substantially anhydrous lotion, cream or gel type deodorant products of the present invention. In this product the polyelectrolyte may be present in an amount of 10 to 30% by weight, preferably 15 to 25% by weight. Deodorant compositions according to the invention preferably also include fragrance, but also other optional minor ingredients. Fragrances are generally included in amounts ranging from 0.1 to 2% by weight. The invention is illustrated by the following examples, in which percentages are by weight. The deodorization test set forth in the Examples was conducted on a panel of approximately 24 or more subjects over five consecutive days as described below. Deodorization Test Day 1 After cleaning and drying both axillae of the panelists, the operator applies a placebo aerosol product to each axilla (2 seconds spray from approximately 15 cm). Next, give the panelists a clean shirt or blouse. Placebo % Isopropyl Myristate 1.0 Fragrance 0.44 Propellant (same as in Example 1) Day 2 to 100.0 Panelist's shirt or blouse removed and arms raised above head Each evaluator (there will be at least three) should be a panelist. sniff both armpits of the patient to determine which side has a stronger armpit odor and give a score indicating whether the right or left armpit has a stronger odor or whether this odor is equally strong. Record. Panelists then evaluate their own axilla in the same manner. After these evaluations, the process from day 1 is repeated. Day 3 Repeat the odor evaluation from day 2. Repeat the washing and spraying of Day 1 again, but instead of applying the placebo, apply the test and control products. In one preselected group of panelists, the test product was applied to the left axilla, the control product was applied to the right axilla, and in the remaining panelists (a group of substantially the same size as the previous group). Apply the test product to the right armpit and the control product to the left armpit. Apply the test and control products in the same manner and in normal consumer usage. For aerosol products, apply in the same manner as for placebos. Day 4 Repeat the operations from day 3. Day 5 Repeat the evaluation done on day 2. A merit score for the test product is calculated from the evaluation (score) obtained in the above test to indicate the magnitude of the difference in deodorizing effect between the test product and the control product. The test side in the second and third day evaluations refers to the side of the panelist's axilla on both sides to which the test product is applied on the third and fourth days, and the side on which the test product is applied on the second day. The control side in the evaluation on the third day refers to the side of the panelist's axilla on both sides to which the control product is applied on the third and fourth days. The test side for evaluations on days 4 and 5 refers to the side of the panelist's bilateral axilla to which the test product is applied, and the control side for evaluations on days 4 and 5 refers to the side of the panelist's bilateral axilla to which the test product is applied. Refers to the side of the axilla to which the control product is applied. Merit Score The merit score associated with the test product is given by the formula: 100/T(A-B-C+D), where A is the rating (score) of the test side having a stronger odor when the placebo is applied on both sides. is the number of B is the number of scores for the control side which has a stronger odor when the placebo is applied bilaterally. C is the number of ratings (scores) of the test side having a stronger odor when the test and control products are applied. D is the number of ratings (scores) of the control side having a stronger odor when the test and control products are applied. T is the total number of evaluations (scores) including those where the odors on both sides are judged to be equal. This merit score is thus determined by the percentage decrease in observations on the test side with a stronger odor (100/T(A-C)) and the percentage increase in observations on the control side with a stronger odor (100/T(D)). -B)). This merit score therefore indicates the magnitude of the difference in deodorizing effectiveness between the test product and the control product. The larger the value of the merit score, the greater the difference in deodorizing effect, indicating that the product has a more excellent deodorizing effect. The practical method of calculating merit scores is explained below using specific numbers. Let's say there are 100 panelists. The evaluation on the second day of the test (evaluation applied to both sides only for the placebo) will have a total of 200 evaluations (100 people x 2 = 200 scores) based on the panelists' own evaluations and the evaluators' evaluations. Assume that there are 80 evaluations (scores) in which the test side has a stronger odor (A = 80), and 120 evaluations in which the control side has a stronger odor (B = 120). The evaluation on the third day of the test (evaluation applied to both sides only for the placebo) was the same as on the second day, with the total number of evaluations (scores)
There will be 200. Of these, there were 110 evaluations (scores) where the test side considered the odor to be strong (A =
110), there are 90 evaluations (scores) indicating that the odor is stronger on the control side (B = 90). The total number of evaluations on the fourth day of the study (evaluation of application of the test product on one side and application of the control product on the other side) will be 200, the same as on the second day. Assume that there is one evaluation (score) in which the test side has a strong odor (C = 1), one evaluation (score) in which both sides have the same odor, and an evaluation (score) in which the odor is strong on the control side (C = 1). Suppose that the score) is 198 (D=198). The total number of evaluations (applying the test product on one side and the control product on the other side) on the fifth day of the study will be 200, the same as on the second day. Of these, there were 5 evaluations (scores) in which the test side was considered to have a strong odor (C = 5), 6 evaluations (scores) in which both sides were judged to have the same odor, and evaluations (scores) in which the control side was judged to have a strong odor. Assume that 189 is hot (D
=189). Therefore, A is 80 + 110 = 190, and B is 120
+90=210, C is 1+5=6, and D is
198+189=387, T=200×4=190+210+
6+387+7 (same odor on both sides)=800. Calculate the merit score by inserting this into the formula that adds the above merit score: Merit score = 100/800 (190-210-6 + 387
)≒45 As a result of the above, this merit score is 45. Significance Test If the distribution of placebo scores on days 2 and 3 are not significantly different at the 5% level, they are merged and the same is done for days 4 and 5; The merged scores for days 4 and 5 are then compared to the merged scores for days 2 and 3. All significance tests were performed using Komogorov-Smirnov analysis (see “Nonparametic
Statistics for the Behavioral Sciences,” International Student Edition, Siegel (S.
Siegel), pp. 127-136, published by McGraw-Hill Kogakusha). All score merits of 20 or higher cited below were statistically significant at the 5% level. Example 1 An aerosol deodorizer spray was prepared with the following composition: % Magnesium Oxide (Heavy) 4.5 Isopropyl Myristate 6.0 Pyrogenic Silica (Aerosil 200) 0.45 Propellant Up to 100.0 This magnesium oxide has an average particle size of approximately 40 microns. and consisted essentially of particles within the range of 10 to 70 microns. Its surface area was approximately 25 m ² /g. The same magnesium oxide was used in subsequent examples. The propellant consisted of a mixture of equal weight parts of propellant 11 (trichlorofluoromethane) and propellant 12 (dichlorodifluoromethane). The composition was prepared by first creating a suspension concentrate by mixing and homogenizing all ingredients except the propellant. The concentrate was placed in a container, which was then sealed with a suitable aerosol valve and pressurized with a propellant. The above products were tested for deodorizing properties in the above deodorization test using Control Product A having the following composition as a control product. Control Product A % Industrial Methylated Spirits 15.0 Isopropyl Militate 0.6 Propellant ¹ Same as in Example ¹ up to 100.0. The product of Example 1 had a merit score of 45. In a second deodorization test conducted as described above except that a placebo product was used as a control, Example 1 had a merit score of 56. Example 2 An aerosol deodorizer spray was made as in Example 1 except that the magnesium oxide was replaced with the same weight of basic magnesium carbonate. In a deodorization test using a placebo product as a control product, the product of this example had a merit score of 31. Example 3 An aerosol deodorizer spray was made with the following composition: % Magnesium Oxide 1.5 Industrial Methylated Spirits 3.0 Hydrophobic Clay (Bentone 38) 0.3 Cetyl Alcohol 0.5 Dipropylene Glycol 0.3 Aqueous Ethyl Alcohol (92% Alcohol) 0.15 Water Absorption Polymer 1.0 Isopropyl myristate 2.0 Propellant ¹ Up to 100.0 Same as in Example ¹ Water-absorbing polymer was “Permasorb 30 Cosmetic Grade” from National Starch and Chemical Company.
It was commercially available under the trade name. It is a potassium salt of polyacrylic acid cross-linked with aluminum ions and is commonly referred to in U.S. Pat. No. 4,090,013
It is stated in the specification of the No. The composition was prepared by first combining isopropyl myristate, dipropylene glycol, cetyl alcohol, and Bentone 38 in a high shear mixer to form a gel. Aqueous ethanol was added to stiffen the gel while continuing to shear the mixture. The water-absorbing polymer was incorporated into the gel until a smooth cream was formed and the same was true for magnesium oxide. The final mixture along with technical methylated spirits was added to an aerosol container, which was sealed with an aerosol valve and pressurized with a propellant. The products were tested in a deodorization test using Control Product A as a control. The product of the invention had a merit score of 29. The product of this example was also compared in a deodorization test to a conventional antiperspirant/deodorant aerosol powder spray based on aluminum chlorohydrate. This product, referred to herein as Control Product B, had the following composition: Control Product B % Aluminum Chlorhydrate 3.75 Isopropyl Myristate 4.92 Pyrogenic Silica (Aerosol 200) ^0.31 Propellant ¹ Up to 100.00 in Example 1 Same as the thing. The product of the invention had a merit score of 1 and there was no significant difference in deodorization between the two products. The product of this example was modified to contain 0.44% fragrance.
It was compared to a similarly modified control product B containing the same amount of the same fragrance in a consumer study using a panel of 700 subjects over a six week period. There was no statistically significant difference between the deodorizing properties of the two products. In the consumer test mentioned, the following test product used was essentially the same as the Example 3 product with some modifications, but using zinc ricinoleate (commercially available under the trade name "Grillocin HY65") instead of magnesium oxide. It can be said that it is a thing. This product was found to be significantly inferior in deodorizing properties compared to the control product. Examples of other suitable water-absorbing polymers which can be used in place of the aforementioned polymers are crosslinked carboxymethyl starch, which is described in German Patent Application No. 2702781, commercially available from Sumitomo Chemical under the trade name Hydrogel S-50 cross-linked saponified copolymer of acrylic acid and vinyl ester, and XD-
It is a crosslinked acrylic polymer commercially available as 857.01. Example 4 An aerosol deodorizer spray was made having the following composition. % Magnesium Oxide 2.0 Isopropyl Myristate 3.0 Cetyl Alcohol 0.5 Aqueous Ethanol (92% Ethanol) 0.3 Hydrophobic Clay (Bentone 38) 0.6 Industrial Methylated Spirits 25.0 Propellant ¹ Up to 100.0 ¹ Same as in Example 1 and Example 3 This product was made by a method similar to that described above for the product. The products were tested for deodorization using the test method described above for Control Product A. The product of this invention is 36
It had a merit score of . Example 5 An aerosol deodorizer spray was made with the following composition: % Magnesium Oxide 2.0 Isopropyl Myristate 2.0 Pyrogenic Silica (Aerosil 200) 0.4 Industrial Methylated Spirits 19.0 Water 52.25 Dimethyl Ether Up to 100.0 Process as described in Example 1 The final step is pressurization of the aerosol container with dimethyl ether propellant. This product was tested for deodorization using the test method described above for Control Product A. The product of the invention had a merit score of 25. Example 6 A deodorant cream was made with the following composition: % Magnesium Oxide 20.0 Glycerol Monostearate 15.0 Sorbitone Monostearate (Span 60) 2.0 Polyoxyethylene Sorbitone Monostearate (Tween 60) 3.0 Glycerin 10.0 Titanium Dioxide 0.5 Water up to 100.0 The three monostearate compounds were first melted and to this mixture a hot mixture of glycerin, 35% water (based on the total amount of the composition) and titanium dioxide was added with stirring. The resulting mixture was allowed to cool before magnesium oxide and remaining water were added with stirring. This mixture was then homogenized. This product was tested for deodorization against Control Product A using the test process described above. The product of the invention had a merit score of 22. Example 7 A deodorizer roll-on product was made with the following composition: % Magnesium Oxide 20.0 Isopropyl Myristate 20.0 Hydrophobic Clay (Bentone 38) 2.0 Cetyl Alcohol 2.0 Aqueous Ethanol (92% Ethanol) 1.0 Industrial Methylated Spirits up to 100.0 The composition was prepared by first mixing isopropyl myristate, Bentone 38 (trade name) and cetyl alcohol in a high shear mixer to form a gel. While continuing to shear the mixture, aqueous ethanol was added to stiffen the gel. Magnesium oxide was then mixed into the gel until a smooth cream was formed. This mixture was then mixed with industrial methylated spirits and filled into a roll-on applicator. This product was tested for deodorization against Roll-on Control Product C using the test process described above.
Control Product C had the following composition: Control Product C % Isopropyl Myristate 25.0 Hydrophobic Clay (Bentone 38) 2.5 Cetyl Alcohol 2.5 Aqueous Ethanol (92% Ethanol) 1.3 Industrial Methylated Spirits Up to 100.0 In the deodorization test The product of the invention had a merit score of 48. Example 8 Below is the composition of a roll-on deodorizer product based on lanthanum oxide. % Lanthanum Oxide 20.0 Isopropyl Myristate 20.0 Hydrophobic Clay (Bentone38) 2.0 Cetyl Alcohol 2.0 Aqueous Ethanol (92% Ethanol) 1.0 Industrial Methylated Spirits Up to 100.0 In the deodorization test, this product has a merit score of 38. Ta. Example 9 This is a deodorizer product of the invention in the form of a bar. % Magnesium Oxide 20.0 Water Absorbing Polymer ¹ 15.0 Sodium Stearate 5.0 Glycerin 3.0 Ethylene Glycol Monoethyl Ether 2.5 Industrial Methylated Spirits ¹ to 100.0 Same as in Example 3. Various other comparative tests were performed. Comparative Test A product identical to that of Example 1 except containing sodium bicarbonate instead of magnesium oxide was compared to Control Product A. The product containing sodium bicarbonate had a merit score of 23. Comparative Test A body powder containing 97% talc and 3% light magnesium oxide was compared to a control product based solely on talc. The magnesium oxide containing powder had a merit score of -11 and was significantly worse than the control product. Comparative Test In this study the control product was the placebo product described above and the test product had the following composition: % Isopropyl Myristate 9.0 Pyrogenic Silica (Aerosil 200) 1.5 Propellant ¹ up to 100.0 as in ^Example 1 The test product had a merit score of -17 and was significantly worse than the control product. Comparative Test A product identical to that of Example 3, with one modification, by substituting magnesium oxide with zinc ricinoleate (commercially available under the trade name "Grillocin HY65"), was compared with Control Product A in a deodorization test. The test product containing zinc ricinoleate as the deodorant active had a merit score of -3 and there was no significant difference in deodorizing properties between the two products. The compatibility of deodorant actives and water-absorbing polymers can be determined by the following test. Compatibility test 0.1 for 1 g of water-absorbing polymer and 2 g of deodorant active substance
A slurry was prepared by adding 40 ml of molar sodium chloride solution. The slurry thus formed was left to equilibrate for 1 h, after which the sample was transferred to a weighed sintered glass tube (weight W ₁ ), then placed in a centrifuge tube and subjected to MSE Super Minor Bench standard swing-arm centrifugation. Centrifuged at 3000 rpm for 1.25 hours in a machine. The sintered tube was then reweighed (weight W ₂ ) and placed in a vacuum oven at 60° C. until dry to dryness (weight W ₃ ). The retention performance (RC ₁ ) of a polymer in the presence of a deodorant active is given by the following formula: W ₂ −W ₃ /W ₃ −W ₁ The retention performance (RC 1 ) of a polymer in the absence of a deodorizer active is given by: ₂ ) is determined in a similar way. Effective absorbency (EA) of the polymer is 100X due to the presence of deodorizer actives
It is given by RC ₁ /RC ₂ . Table 1 shows the retention performance of the polymer shown in Example 3 in the presence of magnesium oxide as the deodorizer active.

[Table] Polymer A is “Permasorb 30 Cosmetic
It is an absorbent known as "Grade" (trade name). Polymer B is a crosslinked carboxymethyl starch as described in German Patent Application No. 2702781. Polymer C is an absorbent known as "Hydrogel S-50" (trade name). Polymer D is an absorbent known as "Polymer XD-857.01" (trade name). Retention capacity and effective absorption values for Polymers A and B in combination with various other deodorant actives of the invention are shown in the table. This table contains data for the widely used deodorant actives aluminum chlorohydrate and zinc phenolsulfonate.

Table: Luphonate The present invention thus provides a formulation of a composition containing a polymer for absorbing perspiration and a non-bactericidal deodorizing active that provides a combination that exhibits both good deodorizing properties and relatively high absorbency. provide

Claims (1)

[Claims] 1. (a) Particulate deodorizer active substance, and (b) 80 as a carrier.
A deodorant composition for reducing body odor in the axilla without inhibiting sweat secretion, comprising a suspension comprising a liquid or gel medium containing less than % by weight of water, wherein said deodorant active ingredient is A deodorizing composition comprising magnesium oxide, magnesium carbonate, lanthanum oxide, or a mixture thereof. 2. A deodorant composition according to claim 1, wherein the deodorant active powder is present in an amount of 0.5 to 30% by weight. 3. The deodorizer active substance is magnesium oxide,
A deodorizing composition according to claim 1 or 2. 4. The deodorizing composition according to claim 1 or 2, wherein the deodorant active substance is basic magnesium carbonate. 5 Claims 1 to 4, which usually also include a gaseous propellant and are in the form of a deodorant spray.
The deodorizing composition according to any one of paragraphs. 6. A deodorizing composition according to any one of claims 1 to 6, wherein the liquid medium as carrier is a lower alcohol or an aqueous alcohol and is in the form of a lotion. 7. A deodorizing composition according to claim 6, which also contains a thickening agent and is packaged in a roll-on applicator. 8. A suspension comprising (a) a particulate deodorant active substance, (b) a substantially anhydrous liquid or gel medium as a carrier, and (c) a water-absorbing anionic polyelectrolyte, which inhibits sweat secretion. 1. A deodorant composition for reducing body odor in the axilla without causing the body odor, characterized in that the deodorant active ingredient is magnesium oxide, magnesium carbonate, lanthanum oxide or a mixture thereof. 9. A deodorizing composition according to claim 8, wherein the water-absorbing polyelectrolyte amounts to 0.5 to 30% by weight of the composition. 10. A deodorant composition according to claim 8, wherein the deodorant active powder is present in an amount of 0.5 to 30% by weight. 11. The deodorant composition according to any one of claims 8 to 10, wherein the deodorant active substance is magnesium oxide. 12. The deodorizing composition according to any one of claims 8 to 10, wherein the deodorant active substance is basic magnesium carbonate. 13. A deodorizing composition according to any one of claims 8 to 12, which also normally comprises a gaseous propellant and is in the form of a deodorant spray. 14. A deodorizing composition according to any one of claims 8 to 12, wherein the liquid medium as a single substance is a lower alcohol and is in the form of a lotion. 15. The deodorizing composition of claim 14, which also contains a thickening agent and is packaged in a roll-on applicator.