JPS6125559A - Nucleus tablet detector of rotary type nucleus provided tablet pressing machine - Google Patents
Nucleus tablet detector of rotary type nucleus provided tablet pressing machineInfo
- Publication number
- JPS6125559A JPS6125559A JP14629984A JP14629984A JPS6125559A JP S6125559 A JPS6125559 A JP S6125559A JP 14629984 A JP14629984 A JP 14629984A JP 14629984 A JP14629984 A JP 14629984A JP S6125559 A JPS6125559 A JP S6125559A
- Authority
- JP
- Japan
- Prior art keywords
- tablet
- powder
- nucleus
- mortar
- color
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/32—Discharging presses
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Glanulating (AREA)
- Sorting Of Articles (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
(産業上の利用分野)
この発明は、核錠の有無を判別して無核錠剤を完全に排
除することができる医薬等の有核錠剤を製造する回転式
有核錠剤機に関するものである。Detailed Description of the Invention (Field of Industrial Application) This invention is a rotary cored tablet for producing cored tablets for pharmaceuticals, etc., which can determine the presence or absence of cored tablets and completely eliminate non-core tablets. It concerns tablet machines.
(従来の技術)
一般に1医薬等に用いる有核錠剤を製造するには、回転
盤に多数配設された臼の中に、第1の粉末を入れ、次に
その粉末の上に碩錠が核錠供給装wによル装置され、そ
の核錠の一五から丈に第2の粉本を充填した後、上杵と
下杵とにより圧縮へれて成形品である有核錠剤を侍るも
のでるる。(Prior art) Generally, in order to manufacture dry-coated tablets used for pharmaceuticals, etc., a first powder is placed in a large number of dies arranged on a rotary disk, and then a small tablet is placed on top of the powder. After filling the core tablet with a second powder to the length of 15 mm, the core tablet is compressed with an upper punch and a lower punch to form a cored tablet as a molded product. It comes out.
従来、との核錠が臼の中に%給された°ということは全
く確認できなかったもので、もし確認Qようとすれば、
製品である有核錠剤を錠剤機から我シ出しだ後、その全
数を重量差等により、無核錠がないことを選別しなけれ
ばならrlまた、その碩縦は小さくなる傾向にあシ、重
量差等の選別は不可能となるものでるり、臼の中に載置
された核錠を直接確認できる本発明は有効なものである
。In the past, it was impossible to confirm that the core lock was fed into the mortar at all, but if you tried to confirm it,
After taking out the dry-coated tablets as a product from the tablet machine, all of them must be sorted to determine whether there are any non-coated tablets, based on weight differences, etc. In addition, the size of the tablets tends to become smaller; Since it is impossible to sort out the difference in weight, etc., the present invention is effective because it allows the core tablets placed in the mortar to be directly confirmed.
(発明が解決しようとする問題点)
医薬等に用いる有核錠剤は、その接縦と周シの錠剤部と
は異種の薬剤から形成されており、それを服用した場合
に体内の2個所以上において作用するものであるが、そ
の有核錠剤を製造する回転式有核錠剤機においては、高
速で回転する回転盤の臼の中に接縦を供給しなければな
らず、その方法としては、回転盤と同期する多数の孔を
有する円板に予め接縦を保持しておき、臼の上方よシそ
の破錠乞/個つつ落し込むようになっている。(Problems to be Solved by the Invention) In dry-coated tablets used for medicine, etc., the vertical and circumferential portions of the tablet are made of different types of drugs, and when the tablet is taken, two or more locations in the body may be affected. However, in a rotary dry-coated tablet machine that manufactures dry-coated tablets, it is necessary to supply a tangent into the mortar of a rotary disk that rotates at high speed, and the method for doing so is as follows: A circular plate with a large number of holes that synchronizes with the rotary disk is held vertically in advance, and the lock is dropped into the upper part of the mortar.
しかしながら、その回転式有核錠剤機が停止した場合に
は慣性によシ接縦が円板の孔よシ飛び出し、これは、円
板の孔に接縦が予め保持されていることを検出器等で確
認した後においても起シうるものでアシ、実際に接縦が
臼の中に供給されていないKも係わらず正常な有核錠剤
であると処理される恐れがある。However, when the rotary cored tablet machine stops, the tangential edge pops out of the hole in the disc due to inertia, which indicates that the tangential edge is previously held in the hole in the disk. This may occur even after confirmation by, etc., and there is a risk that K, which has not actually been fed into the mortar, may be treated as a normal dry-coated tablet.
業だ、IL錠の傷や静電気の影響の為に、予め円板に供
給された接縦が、正常に臼の中に供給されず、即ち全く
供給されなかったシ、供給するタイミングが狂い接縦が
破壊されて飛び出してし筐うものであり、このような接
縦力;入っていない無接縦が製品である有核錠剤の中に
混入することは、その有核錠剤の性買上絶無にしなけれ
ばならないという間融があった。Unfortunately, due to the scratches on the IL lock and the effects of static electricity, the tangent that had been supplied to the disk in advance was not properly fed into the mortar, that is, it was not fed at all, and the timing of the feed was out of order, causing the contact. The vertical part is broken and pops out of the case, and such vertical force; if the unattached vertical part is mixed into the product, a dry-coated tablet, it is absolutely impossible to buy the dry-coated tablet. There was a moment when I had to do something.
(問題点を解決するための手段)
このような問題を解決するために、この発明の構成は、
回転gl(りに配設された臼(2)の臼孔に、第7の粉
末(5りを入れ、該粉末(5a)の上に接縦(7)を1
!L置し、該接縦(7)を被うように第2の粉末(5b
)を充填した後、上杵(17)と下杵(3)とにより圧
縮して有核錠剤uDを製造する回転式有核錠剤機におい
て、第1の粉末(5a)の上に接縦(7)を載置した後
、第2の粉末(5b)を充填するまでの間に色別センサ
ー(4)を配役し、該色別センサー■で粉末(5a)と
接縦(7)の色差を検出することによシ接縦(7)の有
無を判別して無核錠剤を排除するようにした事を特徴と
する回転式有核錠剤機である。(Means for Solving the Problems) In order to solve such problems, the configuration of the present invention is as follows.
Put the seventh powder (5) into the mortar hole of the mortar (2) installed in the rotating gl, and place 1 of the powder (7) vertically on top of the powder (5a).
! Place the second powder (5b) so as to cover the tangent (7).
) is filled and then compressed by an upper punch (17) and a lower punch (3) to produce a dry-coated tablet uD. After placing the powder (7) and before filling the second powder (5b), a color-specific sensor (4) is installed, and the color-specific sensor (■) detects the color difference between the powder (5a) and the tangent (7). This rotary tablet machine with tablets is characterized in that it detects the presence or absence of the clasp (7) and rejects tablets without a core.
(作用) 上記の技術的手段は次の様に作用する。(effect) The above technical means works as follows.
第1の粉末(5a)が入った臼(2)K核縦(7)が供
給即ち載置され、次に第2の粉末(5b)を供給すべく
回転盤(1)は回転するのであるが、その第2の粉末(
5b)が供給される前の位置において、粉末(5a)と
接縦(7)の色の差を色別センサー1fiKよって判別
し、所定の色差を有すれば正常と認識し、もし接縦が載
置されていなければ、その色差を有しないので無接縦と
認識記憶して、良品である刊核錠剤とは別に不良品とし
て排出するものである。The mortar (2) containing the first powder (5a) and the K core vertical (7) are supplied or placed, and then the rotary disk (1) is rotated to supply the second powder (5b). However, the second powder (
At the position before powder 5b) is supplied, the color difference between the powder (5a) and the tangent (7) is determined by the color sensor 1fiK, and if there is a predetermined color difference, it is recognized as normal, and if the tangent is If it is not placed, the color difference is not present, so it is recognized and memorized as having no tangent, and it is discharged as a defective product separately from the good printed core tablets.
なお、色別センサー(4)は、回転する臼(2)と同期
しておシ、たとえ接縦(7)に使用された粉末と第1に
臼(2)の中に入れられる粉末が同色でめったとしても
、接縦t’/) K打錠されたものは少し濃い色となる
為に、その色差を瞬間的に検知し得るものである。In addition, the color-coded sensor (4) feeds the powder in synchronization with the rotating mortar (2), even if the powder used for the vertical grinding (7) and the powder initially put into the mortar (2) are of the same color. Even if it happens, the color difference can be detected instantaneously because the tablets compressed with the vertical t'/)K are a little darker in color.
(実施例)
この発明の一実施例を図面にりいて税関すれば、(1)
は円周上に臼(2)が等間隔に多数配設された回転盤で
ある。(Example) If an example of this invention is shown in the drawings and customs is carried out, (1)
is a rotary disk on which a large number of dies (2) are arranged at equal intervals on the circumference.
(6)は破錠(7)を臼(2)■孔中に俗し込んで供給
するための回転盤(りと同調する破錠供給円板で69、
該破錠供給円板(6)は、その孔中にフィダー@から給
送パイプu3を通って送られてくる接縦(7)を予め保
持しておき、接縦(l)が保持されていることを破錠検
知光電管Uωにより検出し、もし、この接縦(7)が保
持されていない場合には、タイミング光電管u51とタ
イミング孔Umとによる信号か記憶されることにより、
この無接縦となる臼(2)■位置が記憶され、無核錠剤
は排除ダンパーu&により無接縦シュート(ハ)に取シ
出さnる。(6) is a lock-breaking supply disk synchronized with the rotary disk (69) for feeding the broken lock (7) into the hole of the mortar (2).
The lock-breaking supply disc (6) holds in its hole in advance the tangential length (7) sent from the feeder @ through the feeding pipe u3, and the tangential length (l) is held. It is detected by the broken lock detection phototube Uω, and if this tangent (7) is not held, the signal from the timing phototube u51 and the timing hole Um is memorized.
This vertical position of the die (2) is memorized, and the non-nucleated tablet is ejected into the vertical chute (c) by the removal damper u&.
(5a)は臼(2)の孔中に入れられる第1の粉末であ
シ、該粉末(5a)は、粉本落し口u印より溶下し、第
1フイドンユ(4)によシ定量を臼(2)の中に供給き
れる。(5a) is the first powder that is put into the hole of the mortar (2), and the powder (5a) melts down from the powder droplet U mark and is quantitatively determined by the first feeder (4). can be fed into the mortar (2).
(5りは、臼(2)の孔中に上記第1の粉末(5a)が
入シ、次に1核錠(°l)が供給された後、第2フイド
ンユ(811cよシ充填される第2の粉末である。(5) The first powder (5a) is put into the hole of the mortar (2), then one core tablet (°l) is supplied, and then the second powder (811c) is filled. This is the second powder.
(3)け下杵、Uηは上杵、(9)は下杵(8)と上杵
υηを上下よシ圧縮する為の圧縮ロールである。(3) The lower punch, Uη is the upper punch, and (9) is the compression roll for vertically compressing the lower punch (8) and the upper punch υη.
tillは正常に接縦(7)を有して成形された有核錠
剤であり、該有核錠剤11は、ダンパーuO)、シュー
)01)により回転盤(1)の外に取9出され受出(支
)の中に落下する。till is a dry-coated tablet that is normally formed with a vertical axis (7), and the dry-coated tablet 11 is taken out of the rotary disk (1) by a damper uO) and a shoe)01). It falls into the Ude (support).
圓は接縦t’/Jが供給された後節2の粉末が充填され
るlでの間の位置に配設された色別センサーであシ、該
色別センサー囚は、色別信号を発信し受信する検出部(
渉)と、その信号を増幅したシ制御をおこなう制御部(
20a)と、信号を照射するファイバーs (200)
と、安定化電源(#i)とから成るものである。The circle is a color-coded sensor disposed at a position between 1, which is filled with the powder of the rear node 2, which is supplied with the vertical axis t'/J, and the color-coded sensor outputs a color-coded signal. Detection unit that sends and receives signals (
control section (which amplifies the signal and performs control)
20a) and a fiber s (200) for irradiating the signal.
and a stabilized power supply (#i).
この色別センサー(イ)は、通常回転盤(1)の臼(2
)の孔に第1の粉末(5a)が入れられ、次に接縦(′
l)が破錠供給円板(6)によシその粉末(5a)の上
に供給即ち戦mさnた臼(2)の中を色別信号が照射す
ることにより、その粉末(5a)と接縦(7)との色差
を受けて判別し、接縦(7)が供給されていることを認
識し、もし、接縦(7)が載置されていない場合は、色
差がないので接縦(°7)が供給されていないと判2す
し、記憶装置(2)K記憶aせる。This color-coded sensor (A) normally
) is filled with the first powder (5a), and then the tangential and vertical holes ('
l) is fed by the tablet-breaking supply disc (6) onto the powder (5a), i.e., by illuminating the powder (5a) in the mortar (2) with a color-coded signal. It is determined based on the color difference between the tangent and vertical (7), and it recognizes that the tangent and vertical (7) are supplied. If the tangent and vertical (7) are not placed, there is no color difference. It is determined that the tangent (°7) is not supplied, and the memory device (2) K is stored.
そして、この無接縦は、上記記憶装置(2)に接続され
たソレノイド(至)が作動することによシ、排除ダンパ
ーu81を作動させ、無接縦シュート(至)で回転盤(
1)外に排除きれる。Then, this non-tangential vertical chute is operated by operating the solenoid connected to the storage device (2), which activates the exclusion damper u81, and the non-tangential vertical chute (to) operates the rotary disk (
1) It can be excluded outside.
(光力の効果)
以上に説明したように、来光(7)は、接縦が回転盤の
臼の中に供給されるその供給工程後に、色別センサーに
よって直接その臼の中を検知して接縦の有無を判別し得
るものであり、無接縦を完全に排除できるので、他に無
接縦と有核錠剤の選別装置も必要なく、無接縦が有核錠
剤の中に混入することの全くないという医薬等に用いら
れる有核錠剤の性質上重要な品質管理ができる等の効果
を有するものである。(Effect of light power) As explained above, Raikou (7) uses color-coded sensors to directly detect the inside of the mortar after the feeding process in which the tangent is supplied into the mortar of the rotary disk. It is possible to determine the presence or absence of a tangent by using the method, and since it can completely eliminate ungrafted grains, there is no need for any other device to separate the grainless grains from the hard-coated tablets. This has the effect of enabling quality control, which is important due to the nature of dry-coated tablets used for medicines, etc., which require no additional processing.
図面はこの光力による回転式有核錠剤機を示すものであ
シ、第7図は平面図、第2図は正常に有核錠剤が製造さ
れる場合の臼の中の状態等を説明する断面図、第3図は
不良品である無接縦が製造される場合の臼の中の状態等
を説明する断面図である。
図面をておいて、(1)は回転盤、(2)は臼、(3)
は下杵、(4)は第7′ンイドシユ、(5a)(5b)
は粉末、(6)は破錠供給円板、l’/)は接縦、(8
)は第2フイトシユ、(9)は圧縮ロール、Uωはダン
パー、III)は有核錠剤、じはフィダー、u3は給送
パイプ、0りはタイミング孔、(151はタイミング光
電管、u6)は破錠検知光電管、叩は上杵、1榎は排除
ダンパー、(19)は粉末落し口、−ば色別センサー、
(20a)は制御部、(20b)は検出部、(20C)
は7フイバ一部、(20d)は安定化電源、711はン
ユート、困は受出、暖)は無核錠ンユート、(至)はソ
レノイド、IIl!51は記憶装置を示すものである。The drawings show this rotary dry-coated tablet machine using light power. Fig. 7 is a plan view, and Fig. 2 explains the state inside the mortar when normally producing dry-coated tablets. The cross-sectional view and FIG. 3 are cross-sectional views illustrating the state inside the mortar when a defective unjointed vertical piece is manufactured. Based on the drawings, (1) is the turntable, (2) is the mortar, and (3)
(4) is the 7th pestle, (5a) (5b)
is the powder, (6) is the tablet-breaking supply disk, l'/) is the tangent, (8
) is the second fixture, (9) is the compression roll, Uω is the damper, III) is the dry-coated tablet, U is the feeder, u3 is the feeding pipe, 0 is the timing hole, (151 is the timing phototube, u6) is the broken Lock detection phototube, knock is the upper pestle, 1 is the exclusion damper, (19) is the powder outlet, - is the color-coded sensor,
(20a) is a control unit, (20b) is a detection unit, (20C)
is a part of 7 fiber, (20d) is a stabilized power supply, 711 is a power supply, trouble is a reception, warm) is a nuclear-free lock power supply, (to) is a solenoid, IIl! 51 indicates a storage device.
Claims (1)
の粉末(5a)を入れ、該粉末(5a)の上に核錠(7
)を載置し、該核錠(7)を被うように第2の粉末(5
b)を充填した後、上杵(17)と下杵(3)とにより
圧縮して有核錠剤(11)を製造する回転式有核錠剤機
において、第1の粉末(5a)の上に核錠(7)を載置
した後、第2の粉末(5b)を充填するまでの間に色別
センサー(20)を配設し、該色別センサー(20)で
粉末(5a)と核錠(7)の色差を検出することにより
核錠(7)の有無を判別して無核錠剤を排除するように
した事を特徴とする回転式有核錠剤機。1. Insert the first
Powder (5a) is placed on top of the powder (5a).
), and the second powder (5) is placed so as to cover the core tablet (7).
After filling b), in a rotary dry-coated tablet machine that produces a dry-coated tablet (11) by compressing with an upper punch (17) and a lower punch (3), on top of the first powder (5a) After placing the core tablet (7) and before filling the second powder (5b), a color-coded sensor (20) is provided, and the color-coded sensor (20) detects the powder (5a) and core. A rotary cored tablet machine characterized in that the presence or absence of a cored tablet (7) is determined by detecting a color difference between the tablets (7), and non-core tablets are excluded.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14629984A JPS6125559A (en) | 1984-07-13 | 1984-07-13 | Nucleus tablet detector of rotary type nucleus provided tablet pressing machine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14629984A JPS6125559A (en) | 1984-07-13 | 1984-07-13 | Nucleus tablet detector of rotary type nucleus provided tablet pressing machine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6125559A true JPS6125559A (en) | 1986-02-04 |
JPH0246274B2 JPH0246274B2 (en) | 1990-10-15 |
Family
ID=15404535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14629984A Granted JPS6125559A (en) | 1984-07-13 | 1984-07-13 | Nucleus tablet detector of rotary type nucleus provided tablet pressing machine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6125559A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0473456A2 (en) * | 1990-08-31 | 1992-03-04 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | A rotary powder compression molding machine |
JPH09206358A (en) * | 1996-02-06 | 1997-08-12 | Kikusui Seisakusho:Kk | Rotary tablet maker for tablet with nucleus |
WO2017002799A1 (en) * | 2015-06-29 | 2017-01-05 | 株式会社ダイセル | Production method for easy-to-take solid preparation (nucleated tablet), and easy-to-take solid preparation |
-
1984
- 1984-07-13 JP JP14629984A patent/JPS6125559A/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0473456A2 (en) * | 1990-08-31 | 1992-03-04 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | A rotary powder compression molding machine |
JPH09206358A (en) * | 1996-02-06 | 1997-08-12 | Kikusui Seisakusho:Kk | Rotary tablet maker for tablet with nucleus |
WO2017002799A1 (en) * | 2015-06-29 | 2017-01-05 | 株式会社ダイセル | Production method for easy-to-take solid preparation (nucleated tablet), and easy-to-take solid preparation |
CN107708649A (en) * | 2015-06-29 | 2018-02-16 | 株式会社大赛璐 | The manufacture method of easy taking solid pharmaceutical preparation (having chip agent) and easy taking solid pharmaceutical preparation |
TWI690333B (en) * | 2015-06-29 | 2020-04-11 | 日商大賽璐股份有限公司 | Manufacturing method of easy-to-take solid preparation (with nuclear ingot) and easy-to-take solid preparation |
US10959916B2 (en) | 2015-06-29 | 2021-03-30 | Daicel Corporation | Production method for easy-to-take solid preparation (nucleated tablet), and easy-to-take solid preparation |
Also Published As
Publication number | Publication date |
---|---|
JPH0246274B2 (en) | 1990-10-15 |
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