JPH0726074Y2 - Double coated tablet manufacturing equipment - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial field of application] The present invention relates to a tablet for use as a medicine, which is used for producing a double-coated tablet having two core tablets containing another drug therein. The present invention relates to a manufacturing device.

[Prior Art] Generally, when taking, two kinds of medicinal effects are operated separately at different times, or the medicinal effects are changed by changing places such as the stomach and intestines in the body so that the medicinal effects are complicated. A tablet that expects is required.

Therefore, conventionally, the first powder is put into a die hole of a die arranged on a turntable, and a preformed core tablet is supplied onto the die to form a second powder.
There is a dry-coated tablet which is filled with the above powder and compression-molded by an upper punch and a lower punch (for example, see Japanese Patent Application No. 59-177146).

As shown in FIG. 8 and FIG. 9, the dry-coated tablet 31 covers one kernel tablet 33 with a jacket 32.

And, such a dry-coated tablet is, for example, a rotary disk having a mortar, a powder supply means for supplying powder onto the rotary disk, and a part of this powder is placed in the mortar by using the rotation of the rotary disk. A first feedstock to be supplied, a parts feeder (vibration type component feeder) for supplying a core tablet onto the powder in the die introduced by the first feedstock, and a rotary disk in the die to which the core tablet is supplied. A second feedstock for supplying the above powder by using the rotation of the rotary disc, and an upper and lower punches inserted into the upper end of the die passing through the second feedstock and pressed from above and below. It can be manufactured by using a double-coated tablet manufacturing device comprising a compression roll for molding the powder in the die.

[Problems to be Solved by the Invention] In a dry-coated tablet, the powder amount of the core tablet and the powder amount of the envelope are determined according to the intended use (weight ratio 1: 1).
, Etc. are also required), and the kernel lock must be located in the center of the outer cover, but as shown in FIG. 9, there is a problem in that defects occur due to misalignment or inclination of the kernel lock. There is.

That is, if the core tablet 33 is inclined with respect to the outer cover 32 even if the center is not displaced, the wall thickness X of the outer cover 32 covering the core lock 33 becomes thin, which hinders the effect when taken. Needless to say, cracks are likely to occur from the thin portion and the product tends to be defective.

The dry-coated tablet is manufactured by the rotary powder compression molding machine as described above in order to efficiently mass-produce the tablet.
Despite having the ability to make 1100 or more tablets per minute, if the core tablets are put in, there is a problem that the basic ability will not be exhibited and the production efficiency will deteriorate.

That is, to supply the core tablets into the die of the molding machine, as described above, the parts feeder (vibration type parts supply machine) is used, but the core tablets are large, such as long, to ensure the desired weight. In this case, the feeding speed of the parts feeder is significantly reduced, and the entire molding machine must be operated in accordance with this slow feeding speed. For example, in the case of a modified core tablet such as a cylindrical shape as shown in FIG. 9,
It is necessary to align them in the parts feeder and take them out one by one in the longitudinal direction and in a tilted posture. Therefore, it is indispensable to attach a number of attachments in the feed groove of the parts feeder and arrange the nuclear locks in a certain direction, but as the number of attachments increases, the feeding of the nuclear locks stops at that position and the progress is hindered. Therefore, the take-out speed becomes slow. As a result, for example, there is a problem that only about 200 pieces can be fed per minute.

It is an object of the present invention to provide a double-coated tablet manufacturing apparatus capable of efficiently manufacturing a dry-coated tablet without reducing the weight (volume) ratio of the core tablet to the weight of the jacket. I am trying.

[Means for Solving the Problems] In order to achieve the above-mentioned object, a device for producing double-coated tablets according to the present invention comprises a rotating plate having a mortar, and a powder supplying unit for supplying powder onto the rotating plate. A first feedstock for supplying a part of this powder into the die by utilizing the rotation of a rotary disc, and a nuclear tablet supply for dropping two core tablets onto the powder in the die introduced by the first feedstock. Mechanism, a second feedstock for supplying the powder on the rotary disc into the mortar into which the two core tablets have been dropped, by utilizing the rotation of the rotary disc, and the upper end of the mortar passing through the second feedstock. An apparatus for producing a double-nucleated tablet, comprising: an upper punch inserted into the die and a lower punch previously inserted into the lower end of the die, pressed from above and below to form a powder in the die. And the kernel lock supply mechanism has a circular shape in plan view (hereinafter, abbreviated as "round shape"). Oscillating parts feeder that feeds equal weight kernel tablets into two rows of feed pipes while aligning with two rows of guides, and transports while holding two kernel tablets fed through the two rows of feed pipes Further, the present invention is characterized in that it is provided with a nuclear supply plate which is sequentially introduced into the die passing through the first feedstock.

[Operation] Since two round-shaped core tablets having a weight of half of the total weight of the core tablet components to be incorporated are supplied into the die, the supply speed by the vibration type component feeder is reasonably maintained. Can be improved. That is, since the round core tablet has no directionality, it is easy to align, and a complicated alignment attachment that causes a reduction in speed is unnecessary.
Therefore, the nuclear lock can be supplied to the die at high speed by the vibration type component supply machine. Particularly, in the present invention, since the core tablets are aligned by the two rows of guides and fed into the two rows of feed pipes, the weight of core tablets supplied per hour can be significantly increased. Therefore, the operating speed of the entire manufacturing apparatus can be reasonably improved, and the production efficiency can be improved.

Further, in the present invention, since two nuclear locks sent out from the two rows of feed pipes are transferred while being held by the nuclear feed board and are fed into the die, the feeding is more accurate. Can be done in timing.

Further, since the core tablet is a relatively small round shape, even if the core tablet supplied into the die is slightly inclined, the variation in the wall thickness X with the outer cover is reduced. Therefore, it is possible to prevent the production of the dry-coated tablet from cracking.

[Embodiment] An embodiment will be described with reference to the drawings. FIG. 1 to FIG. 4 show an embodiment, FIG. 1 is a plan view of an essential part of the apparatus, and FIG. The tablet is a plan view, FIG. 3 is a semi-longitudinal front view of FIG. 2, and FIG. 4 is a left side view of FIG.

The double barrel-coated tablet 1, which is a flat, oval and approximately barrel-shaped tablet,
Inside, two flat round tablets 3 having a circular shape in a plan view are provided.

A manufacturing apparatus for manufacturing this double-coated tablet 1 comprises a rotary disk 4 having a mortar 5, a powder supplying means 30 for supplying powder 7 onto the rotary disk 4, and a part of the powder 7. Turntable 4
Feeds 6 to be supplied into the die 5 by utilizing the rotation of the
And a nuclear tablet supply mechanism 40 for dropping the two nuclear tablets 3 onto the powder 7 in the die 5 introduced by the first feed shoe 6.
And a second feedstock 9 for supplying the powder 7 on the turntable 4 into the mortar 5 into which the two core tablets 3 have been dropped, by utilizing the rotation of the turntable 4, and the second feedstock 9. A compression roll for pressing the upper punch (not shown) and the lower punch (not shown) inserted into the upper end of the mortar 5 that has passed through the mold from above and below to form the powder 7 in the mortar 5.
It has 10 and.

More specifically, as shown in FIG. 1, the turntable 4 is provided with a plurality of dies 5 near the peripheral edge thereof at a predetermined pitch and is adapted to rotate in the direction of the arrow in the figure.
As is well known, the tip of the lower punch (not shown) is always inserted into the lower end of the die hole of the die 5. The lower pestle is guided by a guide rail (not shown), and is moved up and down by a necessary amount as the turntable 4 rotates. As is well known, an upper punch (not shown) is arranged above each die 5, so that the tip of the upper punch can be inserted into the die 5 after the die 5 has passed through the second feed shoe 9. Has become. Then, after the upper punch and the lower punch have passed through the compression roll 10, the upper punch is removed from the die 5.

The powder supply means 30 has the same structure as the conventional one,
The powder stored in the hopper (not shown) is supplied to the disk surface of the rotary disk 4 from the powder dropping port 18 in appropriate amounts.

The first and second feedstocks 6 and 9 have the same structure as the conventional one, and the fixed guide plates 6a and 9a are used to rotate the rotary disc 4
It is configured so that the powder 7 moving along with the powder can be collected on the mortar 5.

The nuclear lock supply mechanism 40 includes a vibrating component feeder 11 for feeding the same (equal weight) nuclear locks 3 having a circular shape in a plan view into the two rows of feed pipes 12 while aligning them with the two rows of guides 25, and two rows. 2 of the core tablets 3 supplied through the supply pipe 12 of the present invention are transferred while being held and sequentially dropped into the mortar 5 that has passed through the first feed shoe 6. Each supply board 8
Is a disc-shaped member having a plurality of pairs of holding holes 24 corresponding to the outlets of the two rows of the feeding pipes 12 near the outer periphery.
It rotates in the direction of the arrow in the figure. The lower end of the holding hole 24 is normally closed, and is opened only when the holding hole 24 is located right above the mortar 5. Incidentally, 13 is a timing hole for synchronization, and 14 is a timing photoelectric tube. Reference numeral 15 denotes a nuclear detection phototube for detecting whether or not the nuclear lock 3 is held in the holding hole 24. Reference numeral 19 is a detection device which is a color-based sensor for detecting whether or not the core lock 3 is properly supplied from the core lock supply mechanism 40 into the die 5, and 50 is the detection device 19
It is a selection and extraction mechanism that sorts good products and defective products based on the detection and storage results by

After being compressed, the sorting and taking-out mechanism 50 moves the turntable 4 by raising the lower punch.
It is for taking out the double-coated tablet 1 exposed above to the outside, and a take-out damper 17, a chute 20 for guiding non-defective products which is continuous with the take-out damper 17, and a can that is provided at the end of the chute 20. 22, an exclusion damper 16 disposed in front of the take-out damper 17, and the exclusion damper 16
And a solenoid 23 for operating the elimination damper 16. Solenoid 23
Is operated based on the information detected and stored by the detection device 19, and the exclusion damper 16 is lowered onto the turntable 4 only when the approaching dry-coated tablet 1 is defective. Good products can be guided to the elimination chute 21.

With such a structure, the dry-coated tablets can be sequentially and continuously manufactured by the operation according to the conventional manufacturing apparatus.
Since 40 small round core tablets are supplied into the mortar 5 by two, the manufacturing efficiency can be greatly improved. That is, since the round core tablet 3 has no directionality, it can be easily aligned by the vibrating component feeder 11, and a complicated alignment attachment that causes a decrease in speed is unnecessary. Therefore, the nuclear lock can be supplied to the die 5 at high speed by the vibrating component feeder 11. In particular, in this apparatus, the core tablets 3 are aligned by the two rows of guides 25 and fed into the two rows of the feed pipes 12, so that the weight of the core tablets supplied per hour can be greatly increased. Therefore, the operating speed of the entire manufacturing apparatus can be reasonably improved, and the production efficiency can be improved.

As an example, the round-shaped core lock 3 is provided with the vibration-type component feeder.
When sending by 11, it is possible to supply about 2400 pieces per minute. Since this core tablet 3 is half the weight of the conventional cylindrical deformable core tablet 33, the conventional core tablet 33
If converted to the supply rate of 1, the supply capacity will be about 1200 pieces per minute. Therefore, in view of the fact that the limit of the supply speed at the time of feeding the irregular shaped core lock 33 by the vibration type component feeder is about 200 pieces per minute as described above, the core lock supply by the present device. You can see how good your ability is. Therefore, in this apparatus, the operating speed of the entire manufacturing apparatus can be significantly increased as compared with the conventional one, and the production efficiency can be dramatically improved.

5 to 7 show a round core tablet 3 having a spherical shape. According to the manufacturing apparatus described above, such a nuclear tablet 3
It is needless to say that the double-coated tablets having the above can also be efficiently produced in the same manner.

[Effects of the Invention] As described above, the present invention replaces the deformable type nuclear lock, which is difficult to align and difficult to improve the feeding speed,
Since two round core tablets can be supplied by using two rows of guides and two rows of feed pipes, a core tablet of a desired weight can be reliably and rapidly introduced into the die, and the device The effect that the whole operating speed can be reasonably increased to efficiently produce a double-coated tablet having no cracks or the like can be produced.

[Brief description of drawings]

FIG. 1 is a plan view of an essential part of the entire manufacturing apparatus, FIGS. 2 and 5 are plan views of a dry-coated tablet, FIGS. 3 and 6 are semi-longitudinal front views, FIGS. 4 and 7 are left sides. FIG. 8 is a plan view, FIG. 8 is a plan view showing a conventional dry-coated tablet, and FIG. 9 is a semi-longitudinal front view of FIG. 1 ... Nucleated tablet, 2 ... Coat, 3 ... Nuclear tablet, 4 ... Rotary disk, 5 ...
Mortar, 6 ... First feedstock, 7 ... Powder, 8 ... Nuclear supply board,
9 ... 2nd feed shoe, 10 ... Compression roll, 11 ... Oscillation type component feeder, 12 ... Feeding pipe, 13 ... Timing hole, 14 ... Timing photoelectric tube, 15 ... Nuclear detection photoelectric tube, 16 ... Exclusion damper, 17 ... Take out Damper, 18 ... Powder outlet, 19 ... Detection device, 20 ... Chute, 21 ... Exclusion chute, 22 ... Can, 23 ...
Solenoid, 24 ... Retaining hole, 25 ... Guide, 30 ... Powder supply means, 40 ... Core lock supply mechanism, 50 ... Sorting and ejecting mechanism

Claims (1)

[Scope of utility model registration request] 1. A rotary disk (4) having a mortar (5), and powder supply means (30) for supplying powder (7) onto the rotary disk (4).
And a first feedstock (6) for supplying a part of the powder (7) into the mortar (5) by utilizing the rotation of the rotating disk (4),
The mortar (5) introduced by this first feedstock (6)
A nuclear tablet supply mechanism (40) for dropping two core tablets (3) onto the powder (7) inside, and a rotating disk (4) in a mortar (5) into which two core tablets (3) have been dropped. ) A second feedstock (9) for supplying the above powder (7) by using the rotation of the rotary disk (4) and an upper end of the die (5) passing through the second feedstock (9). A double roll provided with an inserted upper punch and a compression roll (10) for pressing the lower punch previously inserted in the lower end of the die from above and below to form the powder (7) in the die (5). A nuclear tablet manufacturing apparatus, wherein the nuclear tablet supply mechanism (40) arranges the nuclear tablets (3) having a circular shape in plan view and having the same weight by means of the two rows of guides (25) and the two rows of feed pipes. The vibrating parts feeder (11) sent to (12) and the two core tablets (3) supplied through the two rows of feed pipes (12) are transferred while being held first. Apparatus for manufacturing a double-nucleated tablet, characterized in that Idoshu (6) is made by including the mortar (5) introduced sequentially to nuclear supply board into a (8) passes through.